| Dataset | Tahoe Therapeutics Tahoe 100M Perturbation Atlas |
| Category | transcriptomics |
| Type | cell type |
| Description | Erlotinib perturbation in COLO 205 cell line (Tahoe Therapeutics) |
| Similar Terms | |
| Downloads & Tools |
200 genes differentially expressed following the Erlotinib_COLO 205 drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| MACC1 | metastasis associated in colon cancer 1 | 0.0925673 |
| VMP1 | vacuole membrane protein 1 | 0.0821398 |
| RUNX1 | runt-related transcription factor 1 | 0.0621827 |
| RALGAPA2 | Ral GTPase activating protein, alpha subunit 2 (catalytic) | 0.0612239 |
| PTBP3 | polypyrimidine tract binding protein 3 | 0.0573216 |
| ZNF292 | zinc finger protein 292 | 0.0515488 |
| SNTB1 | syntrophin, beta 1 (dystrophin-associated protein A1, 59kDa, basic component 1) | 0.0502077 |
| VCL | vinculin | 0.0501227 |
| ARHGEF12 | Rho guanine nucleotide exchange factor (GEF) 12 | 0.0495294 |
| FNDC3B | fibronectin type III domain containing 3B | 0.0493501 |
| TOP2A | topoisomerase (DNA) II alpha 170kDa | 0.0454839 |
| ADAM10 | ADAM metallopeptidase domain 10 | 0.0423371 |
| LCN2 | lipocalin 2 | 0.0405419 |
| IFNGR1 | interferon gamma receptor 1 | 0.0402143 |
| CDC42BPA | CDC42 binding protein kinase alpha (DMPK-like) | 0.0400648 |
| STK24 | serine/threonine kinase 24 | 0.039685 |
| FTH1 | ferritin, heavy polypeptide 1 | 0.0364423 |
| ANXA1 | annexin A1 | 0.03636 |
| UBR2 | ubiquitin protein ligase E3 component n-recognin 2 | 0.0362235 |
| MBOAT2 | membrane bound O-acyltransferase domain containing 2 | 0.0360783 |
| SIPA1L1 | signal-induced proliferation-associated 1 like 1 | 0.0356277 |
| DSPP | dentin sialophosphoprotein | 0.0347187 |
| NFAT5 | nuclear factor of activated T-cells 5, tonicity-responsive | 0.0340475 |
| EREG | epiregulin | 0.0331111 |
| B4GALT5 | UDP-Gal:betaGlcNAc beta 1,4- galactosyltransferase, polypeptide 5 | 0.0328263 |
| EPS8 | epidermal growth factor receptor pathway substrate 8 | 0.0298953 |
| GBE1 | glucan (1,4-alpha-), branching enzyme 1 | 0.0297749 |
| PDZD8 | PDZ domain containing 8 | 0.0289539 |
| UBE2K | ubiquitin-conjugating enzyme E2K | 0.0289525 |
| MAP3K1 | mitogen-activated protein kinase kinase kinase 1, E3 ubiquitin protein ligase | 0.028803 |
| SPIDR | scaffolding protein involved in DNA repair | 0.0285548 |
| PCCA | propionyl CoA carboxylase, alpha polypeptide | 0.028466 |
| NR6A1 | nuclear receptor subfamily 6, group A, member 1 | 0.0283736 |
| ETV6 | ets variant 6 | 0.0283049 |
| DIAPH3 | diaphanous-related formin 3 | 0.0281384 |
| FHIP1A | FHF complex subunit HOOK interacting protein 1A | 0.02805 |
| YAP1 | Yes-associated protein 1 | 0.0277806 |
| TNFRSF21 | tumor necrosis factor receptor superfamily, member 21 | 0.0274059 |
| MAN1A1 | mannosidase, alpha, class 1A, member 1 | 0.0273415 |
| EGLN1 | egl-9 family hypoxia-inducible factor 1 | 0.0270401 |
| KTN1 | kinectin 1 (kinesin receptor) | 0.0269014 |
| UACA | uveal autoantigen with coiled-coil domains and ankyrin repeats | 0.0263219 |
| CMPK1 | cytidine monophosphate (UMP-CMP) kinase 1, cytosolic | 0.026187 |
| PPP1CB | protein phosphatase 1, catalytic subunit, beta isozyme | 0.0257714 |
| TBC1D5 | TBC1 domain family, member 5 | 0.0256891 |
| ARHGAP5 | Rho GTPase activating protein 5 | 0.0255112 |
| CCNL1 | cyclin L1 | 0.0254758 |
| CCDC14 | coiled-coil domain containing 14 | 0.0247898 |
| SSH2 | slingshot protein phosphatase 2 | 0.0243214 |
| HELZ | helicase with zinc finger | 0.0242551 |
| FHIT | fragile histidine triad | 0.024001 |
| GIGYF2 | GRB10 interacting GYF protein 2 | 0.0238644 |
| DENND4C | DENN/MADD domain containing 4C | 0.0238433 |
| MATR3 | matrin 3 | 0.0237281 |
| ERBIN | erbb2 interacting protein | 0.0237183 |
| TBPL1 | TBP-like 1 | 0.0231247 |
| SAMD12 | sterile alpha motif domain containing 12 | 0.0229854 |
| TJP1 | tight junction protein 1 | 0.0227171 |
| SCAPER | S-phase cyclin A-associated protein in the ER | 0.0226776 |
| PCM1 | pericentriolar material 1 | 0.0226072 |
| PDK3 | pyruvate dehydrogenase kinase, isozyme 3 | 0.0224911 |
| YBX3 | Y box binding protein 3 | 0.0223188 |
| SIPA1L2 | signal-induced proliferation-associated 1 like 2 | 0.0222352 |
| RTN4 | reticulon 4 | 0.0221329 |
| LIMA1 | LIM domain and actin binding 1 | 0.0220611 |
| TBK1 | TANK-binding kinase 1 | 0.0216448 |
| CXCL8 | chemokine (C-X-C motif) ligand 8 | 0.0216341 |
| CENPF | centromere protein F, 350/400kDa | 0.0214921 |
| RPL12 | ribosomal protein L12 | 0.0213869 |
| TAS2R14 | taste receptor, type 2, member 14 | 0.0211169 |
| TBL1XR1 | transducin (beta)-like 1 X-linked receptor 1 | 0.0210395 |
| RASSF6 | Ras association (RalGDS/AF-6) domain family member 6 | 0.0208628 |
| CAMTA1 | calmodulin binding transcription activator 1 | 0.0204956 |
| SAA2-SAA4 | SAA2-SAA4 readthrough | 0.0203733 |
| PELI1 | pellino E3 ubiquitin protein ligase 1 | 0.0201048 |
| PDS5B | PDS5 cohesin associated factor B | 0.0200679 |
| WWOX | WW domain containing oxidoreductase | 0.0200566 |
| USP24 | ubiquitin specific peptidase 24 | 0.0200559 |
| RRM2 | ribonucleotide reductase M2 | 0.0199148 |
| KIF5B | kinesin family member 5B | 0.0198838 |
| TPX2 | TPX2, microtubule-associated | 0.0198533 |
| UBAC2 | UBA domain containing 2 | 0.0197884 |
| BRCA1 | breast cancer 1, early onset | 0.0197203 |
| TXNRD1 | thioredoxin reductase 1 | 0.019515 |
| HS2ST1 | heparan sulfate 2-O-sulfotransferase 1 | 0.0194286 |
| RIPK2 | receptor-interacting serine-threonine kinase 2 | 0.0194218 |
| BCLAF1 | BCL2-associated transcription factor 1 | 0.0191875 |
| PACSIN2 | protein kinase C and casein kinase substrate in neurons 2 | 0.0191264 |
| DSTN | destrin (actin depolymerizing factor) | 0.0191009 |
| THOC2 | THO complex 2 | 0.0189588 |
| TRIO | trio Rho guanine nucleotide exchange factor | 0.0189139 |
| IL6ST | interleukin 6 signal transducer | 0.0188609 |
| GPHN | gephyrin | 0.0188251 |
| BBX | bobby sox homolog (Drosophila) | 0.0187249 |
| ANLN | anillin, actin binding protein | 0.0186447 |
| PTP4A2 | protein tyrosine phosphatase type IVA, member 2 | 0.0185707 |
| CLASP1 | cytoplasmic linker associated protein 1 | 0.0184672 |
| WDFY3 | WD repeat and FYVE domain containing 3 | 0.0184655 |
| PTEN | phosphatase and tensin homolog | 0.0184473 |
| KMT2C | lysine (K)-specific methyltransferase 2C | 0.0183464 |
| Symbol | Name | Standardized Value |
|---|---|---|
| TPT1 | tumor protein, translationally-controlled 1 | -0.159988 |
| NDRG1 | N-myc downstream regulated 1 | -0.130476 |
| EPSTI1 | epithelial stromal interaction 1 (breast) | -0.122677 |
| HSP90B1 | heat shock protein 90kDa beta (Grp94), member 1 | -0.114254 |
| RNF213 | ring finger protein 213 | -0.109949 |
| EGR1 | early growth response 1 | -0.109547 |
| SCD | stearoyl-CoA desaturase (delta-9-desaturase) | -0.108751 |
| HLA-B | major histocompatibility complex, class I, B | -0.101179 |
| INTS6 | integrator complex subunit 6 | -0.0991246 |
| DSCAM | Down syndrome cell adhesion molecule | -0.0966539 |
| SQSTM1 | sequestosome 1 | -0.0934843 |
| GAPDH | glyceraldehyde-3-phosphate dehydrogenase | -0.0820569 |
| TXNIP | thioredoxin interacting protein | -0.0819896 |
| AHI1 | Abelson helper integration site 1 | -0.0801819 |
| PKM | pyruvate kinase, muscle | -0.0799324 |
| GOLGB1 | golgin B1 | -0.0777195 |
| LYZ | lysozyme | -0.0756817 |
| MBNL2 | muscleblind-like splicing regulator 2 | -0.0741878 |
| HSPA5 | heat shock 70kDa protein 5 (glucose-regulated protein, 78kDa) | -0.0729221 |
| N4BP2L2 | NEDD4 binding protein 2-like 2 | -0.070885 |
| ANXA2 | annexin A2 | -0.0671286 |
| PTMA | prothymosin, alpha | -0.0664639 |
| P4HB | prolyl 4-hydroxylase, beta polypeptide | -0.0660891 |
| RAB7A | RAB7A, member RAS oncogene family | -0.0638916 |
| RRBP1 | ribosome binding protein 1 | -0.0630951 |
| ZMYND8 | zinc finger, MYND-type containing 8 | -0.062749 |
| PABPC1 | poly(A) binding protein, cytoplasmic 1 | -0.0627323 |
| CALR | calreticulin | -0.0602341 |
| LMO7 | LIM domain 7 | -0.0601807 |
| MORF4L2 | mortality factor 4 like 2 | -0.0563465 |
| PGK1 | phosphoglycerate kinase 1 | -0.0559454 |
| HDLBP | high density lipoprotein binding protein | -0.054879 |
| SREBF2 | sterol regulatory element binding transcription factor 2 | -0.0533452 |
| TMC5 | transmembrane channel-like 5 | -0.0531907 |
| MUC20 | mucin 20, cell surface associated | -0.0528416 |
| HM13 | histocompatibility (minor) 13 | -0.0501246 |
| SEC31A | SEC31 homolog A (S. cerevisiae) | -0.0495055 |
| GNAS | GNAS complex locus | -0.0488239 |
| UGDH | UDP-glucose 6-dehydrogenase | -0.0475821 |
| RIGI | RNA sensor RIG-I | -0.0470178 |
| ZKSCAN1 | zinc finger with KRAB and SCAN domains 1 | -0.0469975 |
| BTBD9 | BTB (POZ) domain containing 9 | -0.0460423 |
| SDC4 | syndecan 4 | -0.0452636 |
| MPHOSPH8 | M-phase phosphoprotein 8 | -0.0449521 |
| IRF1 | interferon regulatory factor 1 | -0.0448913 |
| MCU | mitochondrial calcium uniporter | -0.0438147 |
| RPL19 | ribosomal protein L19 | -0.0435153 |
| GCLC | glutamate-cysteine ligase, catalytic subunit | -0.0426666 |
| H1-0 | H1.0 linker histone | -0.0425403 |
| RBM39 | RNA binding motif protein 39 | -0.0422471 |
| TNFRSF10B | tumor necrosis factor receptor superfamily, member 10b | -0.0417739 |
| HLA-C | major histocompatibility complex, class I, C | -0.0413044 |
| IFI27 | interferon, alpha-inducible protein 27 | -0.0410257 |
| PCK1 | phosphoenolpyruvate carboxykinase 1 (soluble) | -0.0409861 |
| DNAJC15 | DnaJ (Hsp40) homolog, subfamily C, member 15 | -0.0409471 |
| ERO1A | endoplasmic reticulum oxidoreductase 1 alpha | -0.0405598 |
| AHNAK | AHNAK nucleoprotein | -0.0404945 |
| RPL34 | ribosomal protein L34 | -0.0402605 |
| MX2 | MX dynamin-like GTPase 2 | -0.0399805 |
| EIF1 | eukaryotic translation initiation factor 1 | -0.0399082 |
| KIAA1217 | KIAA1217 | -0.0386803 |
| SEMA4B | sema domain, immunoglobulin domain (Ig), transmembrane domain (TM) and short cytoplasmic domain, (semaphorin) 4B | -0.0382196 |
| HCN1 | hyperpolarization activated cyclic nucleotide gated potassium channel 1 | -0.0377058 |
| AP3B1 | adaptor-related protein complex 3, beta 1 subunit | -0.0370318 |
| ARL6IP1 | ADP-ribosylation factor-like 6 interacting protein 1 | -0.0369628 |
| FNDC3A | fibronectin type III domain containing 3A | -0.0368253 |
| ATP1B1 | ATPase, Na+/K+ transporting, beta 1 polypeptide | -0.0366565 |
| COPB2 | coatomer protein complex, subunit beta 2 (beta prime) | -0.036366 |
| WSB1 | WD repeat and SOCS box containing 1 | -0.0360787 |
| ERN1 | endoplasmic reticulum to nucleus signaling 1 | -0.0360575 |
| RPL35A | ribosomal protein L35a | -0.0358283 |
| EIF2AK3 | eukaryotic translation initiation factor 2-alpha kinase 3 | -0.0357444 |
| MLPH | melanophilin | -0.0356603 |
| S100A6 | S100 calcium binding protein A6 | -0.0356035 |
| ANKHD1 | ankyrin repeat and KH domain containing 1 | -0.0354179 |
| RPL7L1 | ribosomal protein L7-like 1 | -0.0349808 |
| TFRC | transferrin receptor | -0.0346806 |
| STAT3 | signal transducer and activator of transcription 3 (acute-phase response factor) | -0.0345994 |
| C6ORF132 | chromosome 6 open reading frame 132 | -0.0343331 |
| SPAG9 | sperm associated antigen 9 | -0.0342858 |
| EZR | ezrin | -0.0339606 |
| FDPS | farnesyl diphosphate synthase | -0.0338651 |
| STAU1 | staufen double-stranded RNA binding protein 1 | -0.0332948 |
| IFI6 | interferon, alpha-inducible protein 6 | -0.0328466 |
| AGR2 | anterior gradient 2 | -0.0327037 |
| ATP2C2 | ATPase, Ca++ transporting, type 2C, member 2 | -0.0325177 |
| TUT7 | terminal uridylyl transferase 7 | -0.0324019 |
| DHRS3 | dehydrogenase/reductase (SDR family) member 3 | -0.0322055 |
| COPB1 | coatomer protein complex, subunit beta 1 | -0.0320105 |
| PRRC2C | proline-rich coiled-coil 2C | -0.0319765 |
| DDIT3 | DNA-damage-inducible transcript 3 | -0.0318322 |
| GCC2 | GRIP and coiled-coil domain containing 2 | -0.0318128 |
| SMIM14 | small integral membrane protein 14 | -0.0314972 |
| TMSB10 | thymosin beta 10 | -0.0309456 |
| ZSWIM6 | zinc finger, SWIM-type containing 6 | -0.0308739 |
| VDAC1 | voltage-dependent anion channel 1 | -0.0308497 |
| SBNO1 | strawberry notch homolog 1 (Drosophila) | -0.0305158 |
| SRRM2 | serine/arginine repetitive matrix 2 | -0.0303495 |
| GNPDA1 | glucosamine-6-phosphate deaminase 1 | -0.0303444 |
| B2M | beta-2-microglobulin | -0.0301891 |
