| Dataset | Tahoe Therapeutics Tahoe 100M Perturbation Atlas |
| Category | transcriptomics |
| Type | cell type |
| Description | Erlotinib perturbation in HepG2/C3A cell line (Tahoe Therapeutics) |
| Similar Terms | |
| Downloads & Tools |
200 genes differentially expressed following the Erlotinib_HepG2/C3A drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| AKAP12 | A kinase (PRKA) anchor protein 12 | 0.0773909 |
| DSPP | dentin sialophosphoprotein | 0.0609893 |
| TRIM26 | tripartite motif containing 26 | 0.0557395 |
| HSP90AB1 | heat shock protein 90kDa alpha (cytosolic), class B member 1 | 0.0539446 |
| PLCB1 | phospholipase C, beta 1 (phosphoinositide-specific) | 0.0370338 |
| ITGA2 | integrin, alpha 2 (CD49B, alpha 2 subunit of VLA-2 receptor) | 0.0342887 |
| EHBP1 | EH domain binding protein 1 | 0.0331097 |
| EIF3A | eukaryotic translation initiation factor 3, subunit A | 0.0317831 |
| HSPD1 | heat shock 60kDa protein 1 (chaperonin) | 0.0312739 |
| SERINC1 | serine incorporator 1 | 0.0309806 |
| SPTBN1 | spectrin, beta, non-erythrocytic 1 | 0.0281975 |
| RPS12 | ribosomal protein S12 | 0.027533 |
| RPL11 | ribosomal protein L11 | 0.0256521 |
| MAML2 | mastermind-like 2 (Drosophila) | 0.0255044 |
| RAI14 | retinoic acid induced 14 | 0.023234 |
| MALRD1 | MAM and LDL receptor class A domain containing 1 | 0.0229154 |
| ARHGAP9 | Rho GTPase activating protein 9 | 0.0227058 |
| NRIP1 | nuclear receptor interacting protein 1 | 0.021952 |
| PLXDC2 | plexin domain containing 2 | 0.0217802 |
| VMP1 | vacuole membrane protein 1 | 0.0215543 |
| MTSS1 | metastasis suppressor 1 | 0.0208498 |
| KIF5B | kinesin family member 5B | 0.020778 |
| HNRNPU | heterogeneous nuclear ribonucleoprotein U (scaffold attachment factor A) | 0.0204766 |
| DSTN | destrin (actin depolymerizing factor) | 0.0203826 |
| RERE | arginine-glutamic acid dipeptide (RE) repeats | 0.0202802 |
| SET | SET nuclear proto-oncogene | 0.0190996 |
| APLP2 | amyloid beta (A4) precursor-like protein 2 | 0.0190935 |
| EEF1B2 | eukaryotic translation elongation factor 1 beta 2 | 0.0186172 |
| RPS17 | ribosomal protein S17 | 0.0183379 |
| RPL26 | ribosomal protein L26 | 0.0175728 |
| GBE1 | glucan (1,4-alpha-), branching enzyme 1 | 0.0174597 |
| AHR | aryl hydrocarbon receptor | 0.0172569 |
| MAGI2 | membrane associated guanylate kinase, WW and PDZ domain containing 2 | 0.0169726 |
| BZW1 | basic leucine zipper and W2 domains 1 | 0.0168972 |
| LRMDA | leucine rich melanocyte differentiation associated | 0.0168789 |
| UGDH | UDP-glucose 6-dehydrogenase | 0.0167057 |
| RSL1D1 | ribosomal L1 domain containing 1 | 0.0166599 |
| ENKUR | enkurin, TRPC channel interacting protein | 0.0166356 |
| HS2ST1 | heparan sulfate 2-O-sulfotransferase 1 | 0.016625 |
| UACA | uveal autoantigen with coiled-coil domains and ankyrin repeats | 0.0163251 |
| HNRNPM | heterogeneous nuclear ribonucleoprotein M | 0.0162867 |
| CNKSR3 | CNKSR family member 3 | 0.0160756 |
| GOLGB1 | golgin B1 | 0.0158558 |
| STAT1 | signal transducer and activator of transcription 1, 91kDa | 0.015535 |
| EPAS1 | endothelial PAS domain protein 1 | 0.0155169 |
| TBL1XR1 | transducin (beta)-like 1 X-linked receptor 1 | 0.0151675 |
| MYO1E | myosin IE | 0.0151416 |
| OSBPL8 | oxysterol binding protein-like 8 | 0.0151161 |
| PTPRN2 | protein tyrosine phosphatase, receptor type, N polypeptide 2 | 0.0150757 |
| VCL | vinculin | 0.0149583 |
| CRY1 | cryptochrome circadian clock 1 | 0.014777 |
| TNFAIP3 | tumor necrosis factor, alpha-induced protein 3 | 0.0146995 |
| FAM107B | family with sequence similarity 107, member B | 0.0146773 |
| SELENOP | selenoprotein P | 0.0144418 |
| IFRD1 | interferon-related developmental regulator 1 | 0.0143517 |
| ITSN2 | intersectin 2 | 0.0138708 |
| LMCD1 | LIM and cysteine-rich domains 1 | 0.0137774 |
| SPIRE1 | spire-type actin nucleation factor 1 | 0.0137016 |
| RC3H1 | ring finger and CCCH-type domains 1 | 0.0136557 |
| RB1CC1 | RB1-inducible coiled-coil 1 | 0.0134653 |
| FOS | FBJ murine osteosarcoma viral oncogene homolog | 0.0134018 |
| PHF3 | PHD finger protein 3 | 0.0133295 |
| PAWR | PRKC, apoptosis, WT1, regulator | 0.0133202 |
| RPL37A | ribosomal protein L37a | 0.0132904 |
| SKI | SKI proto-oncogene | 0.0129891 |
| ABCB1 | ATP-binding cassette, sub-family B (MDR/TAP), member 1 | 0.0129473 |
| NAP1L1 | nucleosome assembly protein 1-like 1 | 0.0128973 |
| UTRN | utrophin | 0.0128161 |
| HIPK2 | homeodomain interacting protein kinase 2 | 0.0127798 |
| SESTD1 | SEC14 and spectrin domains 1 | 0.0127114 |
| PLAC8 | placenta-specific 8 | 0.0127068 |
| SORL1 | sortilin-related receptor, L(DLR class) A repeats containing | 0.0126396 |
| SMAD3 | SMAD family member 3 | 0.0125928 |
| MYO6 | myosin VI | 0.0124901 |
| MORF4L2 | mortality factor 4 like 2 | 0.0123421 |
| SLC20A1 | solute carrier family 20 (phosphate transporter), member 1 | 0.0123331 |
| VPS37A | vacuolar protein sorting 37 homolog A (S. cerevisiae) | 0.0123021 |
| NKD1 | naked cuticle homolog 1 (Drosophila) | 0.0122285 |
| RBBP6 | retinoblastoma binding protein 6 | 0.0121765 |
| TBC1D22A | TBC1 domain family, member 22A | 0.0121451 |
| ELOF1 | elongation factor 1 homolog (S. cerevisiae) | 0.0121219 |
| RAPGEF5 | Rap guanine nucleotide exchange factor (GEF) 5 | 0.011999 |
| HADHA | hydroxyacyl-CoA dehydrogenase/3-ketoacyl-CoA thiolase/enoyl-CoA hydratase (trifunctional protein), alpha subunit | 0.0119934 |
| ANKRD11 | ankyrin repeat domain 11 | 0.0119912 |
| DDAH1 | dimethylarginine dimethylaminohydrolase 1 | 0.0119275 |
| SEPTIN9 | septin 9 | 0.0118316 |
| SERPINB9 | serpin peptidase inhibitor, clade B (ovalbumin), member 9 | 0.0118283 |
| SPSB1 | splA/ryanodine receptor domain and SOCS box containing 1 | 0.0117571 |
| TXNRD1 | thioredoxin reductase 1 | 0.0117279 |
| ASXL1 | additional sex combs like transcriptional regulator 1 | 0.0117251 |
| PITPNC1 | phosphatidylinositol transfer protein, cytoplasmic 1 | 0.0117015 |
| MAP4K4 | mitogen-activated protein kinase kinase kinase kinase 4 | 0.0115298 |
| XRN2 | 5'-3' exoribonuclease 2 | 0.0114804 |
| SOX5 | SRY (sex determining region Y)-box 5 | 0.0114778 |
| HNRNPDL | heterogeneous nuclear ribonucleoprotein D-like | 0.0114187 |
| TNS3 | tensin 3 | 0.0112374 |
| MBD5 | methyl-CpG binding domain protein 5 | 0.0111927 |
| NFE2L1 | nuclear factor, erythroid 2-like 1 | 0.0111664 |
| FKTN | fukutin | 0.0111569 |
| LRRTM4 | leucine rich repeat transmembrane neuronal 4 | 0.0111564 |
| Symbol | Name | Standardized Value |
|---|---|---|
| IGF2 | insulin-like growth factor 2 | -0.534059 |
| SERPINA1 | serpin peptidase inhibitor, clade A (alpha-1 antiproteinase, antitrypsin), member 1 | -0.383809 |
| MT2A | metallothionein 2A | -0.163107 |
| SERPINE1 | serpin peptidase inhibitor, clade E (nexin, plasminogen activator inhibitor type 1), member 1 | -0.134583 |
| C3 | complement component 3 | -0.127213 |
| TIMP1 | TIMP metallopeptidase inhibitor 1 | -0.110902 |
| GAPDH | glyceraldehyde-3-phosphate dehydrogenase | -0.109703 |
| FN1 | fibronectin 1 | -0.105223 |
| SERPINA3 | serpin peptidase inhibitor, clade A (alpha-1 antiproteinase, antitrypsin), member 3 | -0.0937827 |
| PABPC1 | poly(A) binding protein, cytoplasmic 1 | -0.0811916 |
| HSP90B1 | heat shock protein 90kDa beta (Grp94), member 1 | -0.0591733 |
| APOB | apolipoprotein B | -0.0577621 |
| FTL | ferritin, light polypeptide | -0.0571281 |
| TPT1 | tumor protein, translationally-controlled 1 | -0.0536074 |
| A2M | alpha-2-macroglobulin | -0.051185 |
| ENO1 | enolase 1, (alpha) | -0.0504673 |
| NDRG1 | N-myc downstream regulated 1 | -0.049753 |
| APOA2 | apolipoprotein A-II | -0.0441642 |
| ROBO1 | roundabout, axon guidance receptor, homolog 1 (Drosophila) | -0.0423419 |
| AHSG | alpha-2-HS-glycoprotein | -0.0402925 |
| P4HA1 | prolyl 4-hydroxylase, alpha polypeptide I | -0.0389361 |
| ERO1A | endoplasmic reticulum oxidoreductase 1 alpha | -0.0376451 |
| WDR45B | WD repeat domain 45B | -0.0376262 |
| SDC4 | syndecan 4 | -0.0371915 |
| P4HB | prolyl 4-hydroxylase, beta polypeptide | -0.0361698 |
| ELL2 | elongation factor, RNA polymerase II, 2 | -0.0343904 |
| PDIA3 | protein disulfide isomerase family A, member 3 | -0.0334825 |
| PGK1 | phosphoglycerate kinase 1 | -0.0332053 |
| PTTG1IP | pituitary tumor-transforming 1 interacting protein | -0.0330162 |
| TMSB10 | thymosin beta 10 | -0.0330157 |
| LOC112694756 | uncharaterized LOC112694756 | -0.0317912 |
| GOLGA4 | golgin A4 | -0.0312058 |
| PLIN2 | perilipin 2 | -0.0312012 |
| PKM | pyruvate kinase, muscle | -0.0304946 |
| PARD3 | par-3 family cell polarity regulator | -0.0297329 |
| RPL32 | ribosomal protein L32 | -0.0296392 |
| ERRFI1 | ERBB receptor feedback inhibitor 1 | -0.0287297 |
| HELZ | helicase with zinc finger | -0.0282411 |
| PEG3 | paternally expressed 3 | -0.0280136 |
| KCMF1 | potassium channel modulatory factor 1 | -0.0276315 |
| CALR | calreticulin | -0.0266165 |
| RPLP0 | ribosomal protein, large, P0 | -0.0263026 |
| FAM162A | family with sequence similarity 162, member A | -0.026202 |
| PCBP2 | poly(rC) binding protein 2 | -0.0257317 |
| TRAM1 | translocation associated membrane protein 1 | -0.0256753 |
| GLG1 | golgi glycoprotein 1 | -0.0256742 |
| DDIT4 | DNA-damage-inducible transcript 4 | -0.025291 |
| UBR5 | ubiquitin protein ligase E3 component n-recognin 5 | -0.0252887 |
| RPS5 | ribosomal protein S5 | -0.0250978 |
| ADAM9 | ADAM metallopeptidase domain 9 | -0.0250207 |
| WSB1 | WD repeat and SOCS box containing 1 | -0.0246673 |
| BRD4 | bromodomain containing 4 | -0.0245847 |
| HMGA1 | high mobility group AT-hook 1 | -0.024426 |
| MYO1B | myosin IB | -0.024022 |
| PTMA | prothymosin, alpha | -0.0239101 |
| RREB1 | ras responsive element binding protein 1 | -0.0238351 |
| S100A9 | S100 calcium binding protein A9 | -0.0236535 |
| UBE2D2 | ubiquitin-conjugating enzyme E2D 2 | -0.023619 |
| TMEM123 | transmembrane protein 123 | -0.0235474 |
| EXT1 | exostosin glycosyltransferase 1 | -0.0235096 |
| TAX1BP1 | Tax1 (human T-cell leukemia virus type I) binding protein 1 | -0.0234898 |
| APOA1 | apolipoprotein A-I | -0.0234862 |
| CTSB | cathepsin B | -0.0230922 |
| GNAS | GNAS complex locus | -0.0228542 |
| TSC22D2 | TSC22 domain family, member 2 | -0.0228464 |
| PNRC1 | proline-rich nuclear receptor coactivator 1 | -0.0224171 |
| CCNL1 | cyclin L1 | -0.0219347 |
| SETD5 | SET domain containing 5 | -0.0218477 |
| FBF1 | Fas (TNFRSF6) binding factor 1 | -0.0218053 |
| WDFY2 | WD repeat and FYVE domain containing 2 | -0.0216265 |
| RDX | radixin | -0.0214884 |
| CYB5R3 | cytochrome b5 reductase 3 | -0.0214131 |
| SCD | stearoyl-CoA desaturase (delta-9-desaturase) | -0.0214038 |
| KPNB1 | karyopherin (importin) beta 1 | -0.0212954 |
| MT1X | metallothionein 1X | -0.0212475 |
| HNRNPA1 | heterogeneous nuclear ribonucleoprotein A1 | -0.0211926 |
| TM4SF1 | transmembrane 4 L six family member 1 | -0.0211731 |
| ARHGAP12 | Rho GTPase activating protein 12 | -0.0211298 |
| MARCKS | myristoylated alanine-rich protein kinase C substrate | -0.0209347 |
| LMAN1 | lectin, mannose-binding, 1 | -0.0209122 |
| PLOD2 | procollagen-lysine, 2-oxoglutarate 5-dioxygenase 2 | -0.02083 |
| RPL8 | ribosomal protein L8 | -0.0208299 |
| STAU1 | staufen double-stranded RNA binding protein 1 | -0.0206314 |
| SFTPA2 | surfactant protein A2 | -0.0204238 |
| VEZT | vezatin, adherens junctions transmembrane protein | -0.0200589 |
| CNOT1 | CCR4-NOT transcription complex, subunit 1 | -0.0199726 |
| FBXO42 | F-box protein 42 | -0.019961 |
| ZMYND8 | zinc finger, MYND-type containing 8 | -0.0199548 |
| DOCK4 | dedicator of cytokinesis 4 | -0.0198628 |
| NPEPPS | aminopeptidase puromycin sensitive | -0.0198077 |
| UBA6 | ubiquitin-like modifier activating enzyme 6 | -0.01956 |
| KIF21A | kinesin family member 21A | -0.0195027 |
| UGP2 | UDP-glucose pyrophosphorylase 2 | -0.0194248 |
| RBPJ | recombination signal binding protein for immunoglobulin kappa J region | -0.0193875 |
| MAP4K3 | mitogen-activated protein kinase kinase kinase kinase 3 | -0.0191104 |
| RPL35A | ribosomal protein L35a | -0.0187741 |
| XPO1 | exportin 1 | -0.0187589 |
| PIK3C2A | phosphatidylinositol-4-phosphate 3-kinase, catalytic subunit type 2 alpha | -0.018485 |
| ABAT | 4-aminobutyrate aminotransferase | -0.0184707 |
| RPS13 | ribosomal protein S13 | -0.018403 |
