| Dataset | Tahoe Therapeutics Tahoe 100M Perturbation Atlas |
| Category | transcriptomics |
| Type | cell type |
| Description | Erlotinib perturbation in KATO III cell line (Tahoe Therapeutics) |
| Similar Terms | |
| Downloads & Tools |
200 genes differentially expressed following the Erlotinib_KATO III drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| B2M | beta-2-microglobulin | 0.071664 |
| RALGAPA2 | Ral GTPase activating protein, alpha subunit 2 (catalytic) | 0.0696663 |
| TOP2A | topoisomerase (DNA) II alpha 170kDa | 0.0691197 |
| DSPP | dentin sialophosphoprotein | 0.0655019 |
| ZNF292 | zinc finger protein 292 | 0.0581244 |
| CTNNA1 | catenin (cadherin-associated protein), alpha 1, 102kDa | 0.0550278 |
| TMSB4X | thymosin beta 4, X-linked | 0.0534176 |
| FOS | FBJ murine osteosarcoma viral oncogene homolog | 0.0527193 |
| SAMD12 | sterile alpha motif domain containing 12 | 0.0510628 |
| PARP14 | poly (ADP-ribose) polymerase family, member 14 | 0.0489718 |
| RNF213 | ring finger protein 213 | 0.0487987 |
| EZR | ezrin | 0.0463088 |
| YWHAZ | tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, zeta | 0.0446485 |
| SYNE2 | spectrin repeat containing, nuclear envelope 2 | 0.0434715 |
| TPI1 | triosephosphate isomerase 1 | 0.038828 |
| HSP90AB1 | heat shock protein 90kDa alpha (cytosolic), class B member 1 | 0.0387339 |
| CEACAM5 | carcinoembryonic antigen-related cell adhesion molecule 5 | 0.0386578 |
| AHR | aryl hydrocarbon receptor | 0.0383718 |
| SPATS2L | spermatogenesis associated, serine-rich 2-like | 0.0375719 |
| RAD51B | RAD51 paralog B | 0.0367789 |
| TIPARP | TCDD-inducible poly(ADP-ribose) polymerase | 0.0364446 |
| TAX1BP1 | Tax1 (human T-cell leukemia virus type I) binding protein 1 | 0.0363606 |
| RSF1 | remodeling and spacing factor 1 | 0.0355893 |
| ZC3H12B | zinc finger CCCH-type containing 12B | 0.0346756 |
| ADD3 | adducin 3 (gamma) | 0.034024 |
| SERINC1 | serine incorporator 1 | 0.0332833 |
| PRRC2C | proline-rich coiled-coil 2C | 0.0330263 |
| ITM2B | integral membrane protein 2B | 0.0321475 |
| NF1 | neurofibromin 1 | 0.0320394 |
| MTUS1 | microtubule associated tumor suppressor 1 | 0.0319337 |
| FNBP1L | formin binding protein 1-like | 0.0318756 |
| CALM2 | calmodulin 2 (phosphorylase kinase, delta) | 0.031524 |
| PPARG | peroxisome proliferator-activated receptor gamma | 0.0309216 |
| CD2AP | CD2-associated protein | 0.0303346 |
| PLSCR1 | phospholipid scramblase 1 | 0.0302384 |
| RAD21 | RAD21 homolog (S. pombe) | 0.0298225 |
| CBX3 | chromobox homolog 3 | 0.0297066 |
| THOC2 | THO complex 2 | 0.02885 |
| APLP2 | amyloid beta (A4) precursor-like protein 2 | 0.02868 |
| SPTBN1 | spectrin, beta, non-erythrocytic 1 | 0.0285145 |
| RSBN1L | round spermatid basic protein 1-like | 0.0285012 |
| ETV6 | ets variant 6 | 0.0282733 |
| ADAM10 | ADAM metallopeptidase domain 10 | 0.0281981 |
| TNFRSF10B | tumor necrosis factor receptor superfamily, member 10b | 0.0280462 |
| CLMN | calmin (calponin-like, transmembrane) | 0.0273152 |
| EIF2AK2 | eukaryotic translation initiation factor 2-alpha kinase 2 | 0.0268915 |
| DSTN | destrin (actin depolymerizing factor) | 0.0263484 |
| BNIP3L | BCL2/adenovirus E1B 19kDa interacting protein 3-like | 0.026013 |
| EXOC1 | exocyst complex component 1 | 0.0258793 |
| NFE2L1 | nuclear factor, erythroid 2-like 1 | 0.025654 |
| LIMA1 | LIM domain and actin binding 1 | 0.0255616 |
| BCLAF1 | BCL2-associated transcription factor 1 | 0.0254033 |
| HNRNPA2B1 | heterogeneous nuclear ribonucleoprotein A2/B1 | 0.0253777 |
| LY6E | lymphocyte antigen 6 complex, locus E | 0.0253751 |
| CDK6 | cyclin-dependent kinase 6 | 0.0251071 |
| MSI2 | musashi RNA-binding protein 2 | 0.0244246 |
| TMBIM6 | transmembrane BAX inhibitor motif containing 6 | 0.0241483 |
| YAP1 | Yes-associated protein 1 | 0.0241064 |
| ANLN | anillin, actin binding protein | 0.0235638 |
| NAMPT | nicotinamide phosphoribosyltransferase | 0.0235398 |
| PDIA6 | protein disulfide isomerase family A, member 6 | 0.0234479 |
| BBX | bobby sox homolog (Drosophila) | 0.0233973 |
| ASH1L | ash1 (absent, small, or homeotic)-like (Drosophila) | 0.0233793 |
| PTBP3 | polypyrimidine tract binding protein 3 | 0.0233095 |
| TANC1 | tetratricopeptide repeat, ankyrin repeat and coiled-coil containing 1 | 0.0232755 |
| AGR3 | anterior gradient 3 | 0.0232108 |
| RPL26 | ribosomal protein L26 | 0.0231478 |
| NUCKS1 | nuclear casein kinase and cyclin-dependent kinase substrate 1 | 0.023086 |
| TXNIP | thioredoxin interacting protein | 0.0229565 |
| ARFGEF1 | ADP-ribosylation factor guanine nucleotide-exchange factor 1 (brefeldin A-inhibited) | 0.0227317 |
| UACA | uveal autoantigen with coiled-coil domains and ankyrin repeats | 0.022606 |
| CXADR | coxsackie virus and adenovirus receptor | 0.0222459 |
| TPD52 | tumor protein D52 | 0.0222133 |
| ROCK2 | Rho-associated, coiled-coil containing protein kinase 2 | 0.0218862 |
| AKAP9 | A kinase (PRKA) anchor protein 9 | 0.0216134 |
| ST14 | suppression of tumorigenicity 14 (colon carcinoma) | 0.021607 |
| MLEC | malectin | 0.0215544 |
| YWHAG | tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, gamma | 0.0215229 |
| CKAP5 | cytoskeleton associated protein 5 | 0.0214455 |
| ATRX | alpha thalassemia/mental retardation syndrome X-linked | 0.0214317 |
| LPP | LIM domain containing preferred translocation partner in lipoma | 0.0211875 |
| TBC1D5 | TBC1 domain family, member 5 | 0.0211133 |
| ITGA6 | integrin, alpha 6 | 0.0210926 |
| PRELID2 | PRELI domain containing 2 | 0.0209542 |
| IFI27 | interferon, alpha-inducible protein 27 | 0.0209356 |
| ZBTB20 | zinc finger and BTB domain containing 20 | 0.0209119 |
| ZFP36 | ZFP36 ring finger protein | 0.0207938 |
| CLDN7 | claudin 7 | 0.0207544 |
| H1-0 | H1.0 linker histone | 0.0205908 |
| CNKSR3 | CNKSR family member 3 | 0.0204824 |
| ASPM | asp (abnormal spindle) homolog, microcephaly associated (Drosophila) | 0.0203921 |
| XAF1 | XIAP associated factor 1 | 0.0203839 |
| PTPN12 | protein tyrosine phosphatase, non-receptor type 12 | 0.0202341 |
| XPO1 | exportin 1 | 0.0202308 |
| CCDC146 | coiled-coil domain containing 146 | 0.020135 |
| MEF2A | myocyte enhancer factor 2A | 0.0201002 |
| ZNF654 | zinc finger protein 654 | 0.0200577 |
| GOLM2 | golgi membrane protein 2 | 0.0200035 |
| EHBP1 | EH domain binding protein 1 | 0.0199041 |
| BIRC2 | baculoviral IAP repeat containing 2 | 0.0198435 |
| Symbol | Name | Standardized Value |
|---|---|---|
| HSPA5 | heat shock 70kDa protein 5 (glucose-regulated protein, 78kDa) | -0.200807 |
| AGR2 | anterior gradient 2 | -0.094136 |
| HSP90B1 | heat shock protein 90kDa beta (Grp94), member 1 | -0.0923397 |
| NDRG1 | N-myc downstream regulated 1 | -0.0734135 |
| P4HB | prolyl 4-hydroxylase, beta polypeptide | -0.0639651 |
| PABPC1 | poly(A) binding protein, cytoplasmic 1 | -0.0623668 |
| TPT1 | tumor protein, translationally-controlled 1 | -0.0563004 |
| HM13 | histocompatibility (minor) 13 | -0.0550666 |
| ATXN1 | ataxin 1 | -0.0522048 |
| KLHL29 | kelch-like family member 29 | -0.0518902 |
| GMDS | GDP-mannose 4,6-dehydratase | -0.0516805 |
| ITGA2 | integrin, alpha 2 (CD49B, alpha 2 subunit of VLA-2 receptor) | -0.04991 |
| LMO7 | LIM domain 7 | -0.0496592 |
| CEMIP | cell migration inducing protein, hyaluronan binding | -0.0467546 |
| BCL2L1 | BCL2-like 1 | -0.046367 |
| ANXA2 | annexin A2 | -0.0448277 |
| CTNNB1 | catenin (cadherin-associated protein), beta 1, 88kDa | -0.0436322 |
| PDIA4 | protein disulfide isomerase family A, member 4 | -0.0432513 |
| CLTC | clathrin, heavy chain (Hc) | -0.0410314 |
| TMSB10 | thymosin beta 10 | -0.0406416 |
| SLC20A2 | solute carrier family 20 (phosphate transporter), member 2 | -0.0404533 |
| CDK13 | cyclin-dependent kinase 13 | -0.0399744 |
| INTS6 | integrator complex subunit 6 | -0.0397082 |
| EMP1 | epithelial membrane protein 1 | -0.0384638 |
| AREG | amphiregulin | -0.0381859 |
| PGK1 | phosphoglycerate kinase 1 | -0.0378868 |
| ATP1B1 | ATPase, Na+/K+ transporting, beta 1 polypeptide | -0.0376287 |
| TNFRSF21 | tumor necrosis factor receptor superfamily, member 21 | -0.0367252 |
| COPB2 | coatomer protein complex, subunit beta 2 (beta prime) | -0.035333 |
| MBNL2 | muscleblind-like splicing regulator 2 | -0.03494 |
| HMGCS1 | 3-hydroxy-3-methylglutaryl-CoA synthase 1 (soluble) | -0.0345677 |
| POTEF | POTE ankyrin domain family, member F | -0.0345156 |
| GAPDH | glyceraldehyde-3-phosphate dehydrogenase | -0.0343518 |
| FTL | ferritin, light polypeptide | -0.0342358 |
| ACTG1 | actin gamma 1 | -0.0341177 |
| AHNAK | AHNAK nucleoprotein | -0.0339363 |
| RAB7A | RAB7A, member RAS oncogene family | -0.0336798 |
| SLC7A11 | solute carrier family 7 (anionic amino acid transporter light chain, xc- system), member 11 | -0.0334638 |
| ARHGAP29 | Rho GTPase activating protein 29 | -0.0329414 |
| PTMA | prothymosin, alpha | -0.0325035 |
| CD55 | CD55 molecule, decay accelerating factor for complement (Cromer blood group) | -0.0318595 |
| HDLBP | high density lipoprotein binding protein | -0.0314482 |
| RABGEF1 | RAB guanine nucleotide exchange factor (GEF) 1 | -0.0312389 |
| WDR45B | WD repeat domain 45B | -0.0307522 |
| PKM | pyruvate kinase, muscle | -0.0298535 |
| FRMD5 | FERM domain containing 5 | -0.0295108 |
| SLCO1B3-SLCO1B7 | SLCO1B3-SLCO1B7 readthrough | -0.0294446 |
| RPL38 | ribosomal protein L38 | -0.0288472 |
| ZSWIM6 | zinc finger, SWIM-type containing 6 | -0.0288364 |
| PPIB | peptidylprolyl isomerase B (cyclophilin B) | -0.0283319 |
| KRT8 | keratin 8, type II | -0.0280915 |
| RPS16 | ribosomal protein S16 | -0.0280607 |
| C6ORF132 | chromosome 6 open reading frame 132 | -0.0275221 |
| FLNB | filamin B, beta | -0.0273801 |
| SEC31A | SEC31 homolog A (S. cerevisiae) | -0.027341 |
| CALU | calumenin | -0.0272564 |
| PTPRK | protein tyrosine phosphatase, receptor type, K | -0.0268565 |
| PLEC | plectin | -0.0266727 |
| RAB1A | RAB1A, member RAS oncogene family | -0.0266469 |
| MCL1 | myeloid cell leukemia 1 | -0.0263069 |
| PMM2 | phosphomannomutase 2 | -0.0259943 |
| PDIA3 | protein disulfide isomerase family A, member 3 | -0.0258795 |
| CUX1 | cut-like homeobox 1 | -0.025725 |
| VCL | vinculin | -0.0255989 |
| SLCO1B3 | solute carrier organic anion transporter family, member 1B3 | -0.0254098 |
| KCNIP4 | Kv channel interacting protein 4 | -0.025318 |
| RPS29 | ribosomal protein S29 | -0.0251781 |
| ATF7IP2 | activating transcription factor 7 interacting protein 2 | -0.0250946 |
| ZNF207 | zinc finger protein 207 | -0.0242402 |
| EFNB2 | ephrin-B2 | -0.0240258 |
| MORF4L2 | mortality factor 4 like 2 | -0.0238839 |
| CHCHD2 | coiled-coil-helix-coiled-coil-helix domain containing 2 | -0.0233773 |
| LARP1B | La ribonucleoprotein domain family, member 1B | -0.0233475 |
| INSIG1 | insulin induced gene 1 | -0.0232808 |
| ADIPOR2 | adiponectin receptor 2 | -0.0230327 |
| CMIP | c-Maf inducing protein | -0.0229556 |
| CAPN8 | calpain 8 | -0.0226886 |
| PDXDC1 | pyridoxal-dependent decarboxylase domain containing 1 | -0.022647 |
| HMGA1 | high mobility group AT-hook 1 | -0.022586 |
| AAK1 | AP2 associated kinase 1 | -0.0225432 |
| DSG2 | desmoglein 2 | -0.0224475 |
| STX5 | syntaxin 5 | -0.0223996 |
| POLR2A | polymerase (RNA) II (DNA directed) polypeptide A, 220kDa | -0.022309 |
| CATSPERB | catsper channel auxiliary subunit beta | -0.022255 |
| STAU1 | staufen double-stranded RNA binding protein 1 | -0.0222419 |
| POF1B | premature ovarian failure, 1B | -0.0220088 |
| RPL35A | ribosomal protein L35a | -0.0219862 |
| TFRC | transferrin receptor | -0.0218807 |
| ARCN1 | archain 1 | -0.0218751 |
| KDM3A | lysine (K)-specific demethylase 3A | -0.0217388 |
| MCU | mitochondrial calcium uniporter | -0.0217017 |
| SND1 | staphylococcal nuclease and tudor domain containing 1 | -0.0214721 |
| COTL1 | coactosin-like F-actin binding protein 1 | -0.0214083 |
| SLC2A1 | solute carrier family 2 (facilitated glucose transporter), member 1 | -0.0213885 |
| PPP1R10 | protein phosphatase 1, regulatory subunit 10 | -0.0211743 |
| PDIA5 | protein disulfide isomerase family A, member 5 | -0.0211529 |
| FLNA | filamin A, alpha | -0.0210276 |
| DLC1 | DLC1 Rho GTPase activating protein | -0.0210217 |
| ANXA3 | annexin A3 | -0.0206511 |
| GNB1 | guanine nucleotide binding protein (G protein), beta polypeptide 1 | -0.0206253 |
