| Dataset | Tahoe Therapeutics Tahoe 100M Perturbation Atlas |
| Category | transcriptomics |
| Type | cell type |
| Description | Erlotinib perturbation in LS 180 cell line (Tahoe Therapeutics) |
| Similar Terms | |
| Downloads & Tools |
200 genes differentially expressed following the Erlotinib_LS 180 drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| GAPDH | glyceraldehyde-3-phosphate dehydrogenase | 0.251298 |
| HSP90AB1 | heat shock protein 90kDa alpha (cytosolic), class B member 1 | 0.16261 |
| HSPA5 | heat shock 70kDa protein 5 (glucose-regulated protein, 78kDa) | 0.126391 |
| HSP90B1 | heat shock protein 90kDa beta (Grp94), member 1 | 0.121975 |
| FTH1 | ferritin, heavy polypeptide 1 | 0.108154 |
| LDHA | lactate dehydrogenase A | 0.100036 |
| EREG | epiregulin | 0.0999068 |
| RPS6 | ribosomal protein S6 | 0.0944524 |
| TXNIP | thioredoxin interacting protein | 0.0827033 |
| GOLGA4 | golgin A4 | 0.0817152 |
| DSPP | dentin sialophosphoprotein | 0.0816487 |
| FAM13A | family with sequence similarity 13, member A | 0.0811214 |
| HSPD1 | heat shock 60kDa protein 1 (chaperonin) | 0.0749079 |
| RPS12 | ribosomal protein S12 | 0.0736025 |
| RPS2 | ribosomal protein S2 | 0.0678779 |
| MDM2 | MDM2 proto-oncogene, E3 ubiquitin protein ligase | 0.0645358 |
| RPL12 | ribosomal protein L12 | 0.0636075 |
| EEF2 | eukaryotic translation elongation factor 2 | 0.0616738 |
| AREG | amphiregulin | 0.0616102 |
| GPRC5A | G protein-coupled receptor, class C, group 5, member A | 0.0612336 |
| EIF1 | eukaryotic translation initiation factor 1 | 0.0602309 |
| TNFRSF10B | tumor necrosis factor receptor superfamily, member 10b | 0.0591708 |
| FOS | FBJ murine osteosarcoma viral oncogene homolog | 0.0589256 |
| RPS8 | ribosomal protein S8 | 0.0552265 |
| RPLP0 | ribosomal protein, large, P0 | 0.0548976 |
| EZR | ezrin | 0.054456 |
| KIF5B | kinesin family member 5B | 0.0533364 |
| RPL26 | ribosomal protein L26 | 0.0533336 |
| P4HA1 | prolyl 4-hydroxylase, alpha polypeptide I | 0.0512342 |
| GDF15 | growth differentiation factor 15 | 0.0511234 |
| DDIT4 | DNA-damage-inducible transcript 4 | 0.0490525 |
| ZNF292 | zinc finger protein 292 | 0.048108 |
| MLEC | malectin | 0.0458184 |
| RACK1 | receptor for activated C kinase 1 | 0.0445596 |
| RPS3 | ribosomal protein S3 | 0.0440507 |
| RPLP1 | ribosomal protein, large, P1 | 0.0439384 |
| SLC12A2 | solute carrier family 12 (sodium/potassium/chloride transporter), member 2 | 0.0423244 |
| RNF43 | ring finger protein 43 | 0.0414546 |
| RPL11 | ribosomal protein L11 | 0.0413433 |
| RBPJ | recombination signal binding protein for immunoglobulin kappa J region | 0.0410416 |
| CANX | calnexin | 0.0407758 |
| DSTN | destrin (actin depolymerizing factor) | 0.0403255 |
| TIPARP | TCDD-inducible poly(ADP-ribose) polymerase | 0.0399622 |
| ANXA1 | annexin A1 | 0.0398713 |
| RNF145 | ring finger protein 145 | 0.039685 |
| PTBP3 | polypyrimidine tract binding protein 3 | 0.0392351 |
| GARS1 | glycyl-tRNA synthetase 1 | 0.0390245 |
| GFPT1 | glutamine--fructose-6-phosphate transaminase 1 | 0.0375579 |
| NPM1 | nucleophosmin (nucleolar phosphoprotein B23, numatrin) | 0.037321 |
| EPCAM | epithelial cell adhesion molecule | 0.0366922 |
| KMT2E | lysine (K)-specific methyltransferase 2E | 0.0365875 |
| RPS19 | ribosomal protein S19 | 0.0359565 |
| APLP2 | amyloid beta (A4) precursor-like protein 2 | 0.0353204 |
| B2M | beta-2-microglobulin | 0.0352058 |
| FHIP1A | FHF complex subunit HOOK interacting protein 1A | 0.0350324 |
| TXNRD1 | thioredoxin reductase 1 | 0.0349964 |
| RPL37A | ribosomal protein L37a | 0.0346906 |
| RPL7 | ribosomal protein L7 | 0.034193 |
| ENO1 | enolase 1, (alpha) | 0.0336247 |
| MXI1 | MAX interactor 1, dimerization protein | 0.0334775 |
| RPL13A | ribosomal protein L13a | 0.0331723 |
| FTL | ferritin, light polypeptide | 0.0330422 |
| LOC102724023 | ES1 protein homolog, mitochondrial | 0.032406 |
| EPRS1 | glutamyl-prolyl-tRNA synthetase 1 | 0.0323434 |
| PRELID2 | PRELI domain containing 2 | 0.0318286 |
| PABPC1 | poly(A) binding protein, cytoplasmic 1 | 0.031786 |
| TMBIM6 | transmembrane BAX inhibitor motif containing 6 | 0.0317428 |
| LOC112694756 | uncharaterized LOC112694756 | 0.0316486 |
| RPS27 | ribosomal protein S27 | 0.0313905 |
| LIMA1 | LIM domain and actin binding 1 | 0.0311865 |
| UBC | ubiquitin C | 0.0308403 |
| TRIM2 | tripartite motif containing 2 | 0.0307147 |
| RPL18 | ribosomal protein L18 | 0.0306913 |
| MUC13 | mucin 13, cell surface associated | 0.0304837 |
| NAMPT | nicotinamide phosphoribosyltransferase | 0.0302458 |
| ANKRD11 | ankyrin repeat domain 11 | 0.0298948 |
| KTN1 | kinectin 1 (kinesin receptor) | 0.0297325 |
| TM9SF3 | transmembrane 9 superfamily member 3 | 0.0290226 |
| RAB3GAP1 | RAB3 GTPase activating protein subunit 1 (catalytic) | 0.0287625 |
| TGFBR2 | transforming growth factor, beta receptor II (70/80kDa) | 0.0287475 |
| RPS23 | ribosomal protein S23 | 0.0287388 |
| NEK7 | NIMA-related kinase 7 | 0.028545 |
| PTEN | phosphatase and tensin homolog | 0.0284078 |
| VEGFA | vascular endothelial growth factor A | 0.0280356 |
| RLF | rearranged L-myc fusion | 0.0279975 |
| YWHAZ | tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, zeta | 0.0277292 |
| RPL23 | ribosomal protein L23 | 0.0277287 |
| AKAP9 | A kinase (PRKA) anchor protein 9 | 0.0276536 |
| MTHFD2 | methylenetetrahydrofolate dehydrogenase (NADP+ dependent) 2, methenyltetrahydrofolate cyclohydrolase | 0.0276371 |
| GPBP1 | GC-rich promoter binding protein 1 | 0.0274885 |
| TAF1D | TATA box binding protein (TBP)-associated factor, RNA polymerase I, D, 41kDa | 0.0274197 |
| VMP1 | vacuole membrane protein 1 | 0.027277 |
| MBNL2 | muscleblind-like splicing regulator 2 | 0.0267767 |
| RPL32 | ribosomal protein L32 | 0.0267682 |
| WDR45B | WD repeat domain 45B | 0.0264942 |
| TPD52 | tumor protein D52 | 0.0260853 |
| CSDE1 | cold shock domain containing E1, RNA-binding | 0.026057 |
| PTPRR | protein tyrosine phosphatase, receptor type, R | 0.02601 |
| PCDHB16 | protocadherin beta 16 | 0.0260067 |
| EIF3A | eukaryotic translation initiation factor 3, subunit A | 0.0259936 |
| Symbol | Name | Standardized Value |
|---|---|---|
| NPSR1 | neuropeptide S receptor 1 | -0.169221 |
| CD55 | CD55 molecule, decay accelerating factor for complement (Cromer blood group) | -0.154884 |
| GMDS | GDP-mannose 4,6-dehydratase | -0.11169 |
| GRIN2B | glutamate receptor, ionotropic, N-methyl D-aspartate 2B | -0.109995 |
| NALF1 | NALCN channel auxiliary factor 1 | -0.0965379 |
| ONECUT3 | one cut homeobox 3 | -0.0920132 |
| GREB1L | growth regulation by estrogen in breast cancer-like | -0.0850907 |
| ANTXR2 | anthrax toxin receptor 2 | -0.0836186 |
| ASPH | aspartate beta-hydroxylase | -0.0782001 |
| CEMIP | cell migration inducing protein, hyaluronan binding | -0.0743775 |
| ACTG1 | actin gamma 1 | -0.0705189 |
| AGAP1 | ArfGAP with GTPase domain, ankyrin repeat and PH domain 1 | -0.0703048 |
| PITPNC1 | phosphatidylinositol transfer protein, cytoplasmic 1 | -0.0693192 |
| TMSB10 | thymosin beta 10 | -0.0684514 |
| FLNB | filamin B, beta | -0.0661165 |
| AHNAK | AHNAK nucleoprotein | -0.0657121 |
| PTPRK | protein tyrosine phosphatase, receptor type, K | -0.062451 |
| PSD3 | pleckstrin and Sec7 domain containing 3 | -0.0618866 |
| ALCAM | activated leukocyte cell adhesion molecule | -0.058352 |
| SLC35F3 | solute carrier family 35, member F3 | -0.0580961 |
| FAT1 | FAT atypical cadherin 1 | -0.0544041 |
| LAMA4 | laminin, alpha 4 | -0.0506582 |
| TPT1 | tumor protein, translationally-controlled 1 | -0.0503233 |
| MAML3 | mastermind-like 3 (Drosophila) | -0.0499932 |
| EGFR | epidermal growth factor receptor | -0.0499541 |
| ST3GAL1 | ST3 beta-galactoside alpha-2,3-sialyltransferase 1 | -0.0491518 |
| ACTN4 | actinin, alpha 4 | -0.0471325 |
| ITGA6 | integrin, alpha 6 | -0.0458193 |
| KRT8 | keratin 8, type II | -0.044599 |
| MYO1E | myosin IE | -0.0430384 |
| PTMA | prothymosin, alpha | -0.0421119 |
| MUC5AC | mucin 5AC, oligomeric mucus/gel-forming | -0.0418909 |
| IMMP2L | IMP2 inner mitochondrial membrane peptidase-like (S. cerevisiae) | -0.0415712 |
| VCL | vinculin | -0.0411339 |
| MPRIP | myosin phosphatase Rho interacting protein | -0.0407268 |
| DCBLD2 | discoidin, CUB and LCCL domain containing 2 | -0.0405125 |
| EXT1 | exostosin glycosyltransferase 1 | -0.0404596 |
| SAMD5 | sterile alpha motif domain containing 5 | -0.0404481 |
| RNF217 | ring finger protein 217 | -0.0402516 |
| BACE2 | beta-site APP-cleaving enzyme 2 | -0.0382209 |
| B4GALNT3 | beta-1,4-N-acetyl-galactosaminyl transferase 3 | -0.0369676 |
| FERMT1 | fermitin family member 1 | -0.0360176 |
| PPP3CA | protein phosphatase 3, catalytic subunit, alpha isozyme | -0.0359153 |
| SH3D19 | SH3 domain containing 19 | -0.0352769 |
| SVIL | supervillin | -0.035268 |
| DDX5 | DEAD (Asp-Glu-Ala-Asp) box helicase 5 | -0.0348432 |
| PARD3 | par-3 family cell polarity regulator | -0.0347245 |
| CEACAM5 | carcinoembryonic antigen-related cell adhesion molecule 5 | -0.0347068 |
| NAB1 | NGFI-A binding protein 1 (EGR1 binding protein 1) | -0.03455 |
| LPP | LIM domain containing preferred translocation partner in lipoma | -0.0343605 |
| SMYD3 | SET and MYND domain containing 3 | -0.034027 |
| EHBP1 | EH domain binding protein 1 | -0.0326079 |
| GNB1 | guanine nucleotide binding protein (G protein), beta polypeptide 1 | -0.0316114 |
| RAD51B | RAD51 paralog B | -0.0313364 |
| LRCH1 | leucine-rich repeats and calponin homology (CH) domain containing 1 | -0.0311563 |
| MACF1 | microtubule-actin crosslinking factor 1 | -0.0307781 |
| ATP1B1 | ATPase, Na+/K+ transporting, beta 1 polypeptide | -0.0300636 |
| SOX4 | SRY (sex determining region Y)-box 4 | -0.0300189 |
| ITGA2 | integrin, alpha 2 (CD49B, alpha 2 subunit of VLA-2 receptor) | -0.0296263 |
| CMIP | c-Maf inducing protein | -0.0295745 |
| SLCO1B3-SLCO1B7 | SLCO1B3-SLCO1B7 readthrough | -0.0293455 |
| IGF1R | insulin-like growth factor 1 receptor | -0.0290436 |
| F3 | coagulation factor III (thromboplastin, tissue factor) | -0.0288263 |
| FRMD5 | FERM domain containing 5 | -0.0285594 |
| DENND1A | DENN/MADD domain containing 1A | -0.0285265 |
| SLCO1B3 | solute carrier organic anion transporter family, member 1B3 | -0.0284757 |
| RAB10 | RAB10, member RAS oncogene family | -0.0281126 |
| FUT8 | fucosyltransferase 8 (alpha (1,6) fucosyltransferase) | -0.0278891 |
| ABR | active BCR-related | -0.027789 |
| PDE4D | phosphodiesterase 4D, cAMP-specific | -0.0276022 |
| RCOR1 | REST corepressor 1 | -0.027449 |
| KRT18 | keratin 18, type I | -0.0273449 |
| MED13 | mediator complex subunit 13 | -0.0273427 |
| SLC2A1 | solute carrier family 2 (facilitated glucose transporter), member 1 | -0.0269991 |
| MYH9 | myosin, heavy chain 9, non-muscle | -0.0269981 |
| HNRNPU | heterogeneous nuclear ribonucleoprotein U (scaffold attachment factor A) | -0.0269017 |
| TFF1 | trefoil factor 1 | -0.026829 |
| PMEPA1 | prostate transmembrane protein, androgen induced 1 | -0.0268218 |
| PDLIM5 | PDZ and LIM domain 5 | -0.0267429 |
| PHLDB2 | pleckstrin homology-like domain, family B, member 2 | -0.0265538 |
| HSPG2 | heparan sulfate proteoglycan 2 | -0.0259328 |
| CCND1 | cyclin D1 | -0.0257299 |
| FHIT | fragile histidine triad | -0.0256021 |
| MGAT5 | mannosyl (alpha-1,6-)-glycoprotein beta-1,6-N-acetyl-glucosaminyltransferase | -0.0253493 |
| OSBPL10 | oxysterol binding protein-like 10 | -0.0252822 |
| MSI2 | musashi RNA-binding protein 2 | -0.0251035 |
| DIAPH2 | diaphanous-related formin 2 | -0.0249879 |
| HMGB1 | high mobility group box 1 | -0.0249189 |
| PLEC | plectin | -0.0248313 |
| BCAT1 | branched chain amino-acid transaminase 1, cytosolic | -0.0244286 |
| LSAMP | limbic system-associated membrane protein | -0.0244022 |
| MT2A | metallothionein 2A | -0.0243992 |
| SLC5A3 | solute carrier family 5 (sodium/myo-inositol cotransporter), member 3 | -0.0243258 |
| DIP2B | DIP2 disco-interacting protein 2 homolog B (Drosophila) | -0.0240983 |
| EFNB2 | ephrin-B2 | -0.0239475 |
| ANO1 | anoctamin 1, calcium activated chloride channel | -0.0238777 |
| KDM4C | lysine (K)-specific demethylase 4C | -0.0237296 |
| VCAN | versican | -0.0233141 |
| ANKRD10 | ankyrin repeat domain 10 | -0.0232384 |
| ASAP2 | ArfGAP with SH3 domain, ankyrin repeat and PH domain 2 | -0.0231543 |
