| Dataset | Tahoe Therapeutics Tahoe 100M Perturbation Atlas |
| Category | transcriptomics |
| Type | cell type |
| Description | Erlotinib perturbation in MIA PaCa-2 cell line (Tahoe Therapeutics) |
| Similar Terms | |
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200 genes differentially expressed following the Erlotinib_MIA PaCa-2 drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| TXNRD1 | thioredoxin reductase 1 | 0.100759 |
| BZW1 | basic leucine zipper and W2 domains 1 | 0.0552284 |
| HSP90AB1 | heat shock protein 90kDa alpha (cytosolic), class B member 1 | 0.0457405 |
| UAP1 | UDP-N-acetylglucosamine pyrophosphorylase 1 | 0.0444042 |
| HSPA5 | heat shock 70kDa protein 5 (glucose-regulated protein, 78kDa) | 0.0331591 |
| YWHAG | tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, gamma | 0.0331404 |
| EREG | epiregulin | 0.0323698 |
| EIF3A | eukaryotic translation initiation factor 3, subunit A | 0.0317937 |
| ANXA1 | annexin A1 | 0.0302825 |
| GARS1 | glycyl-tRNA synthetase 1 | 0.0288566 |
| RPS2 | ribosomal protein S2 | 0.0275767 |
| UPP1 | uridine phosphorylase 1 | 0.0250203 |
| RPL26 | ribosomal protein L26 | 0.024663 |
| BNIP3L | BCL2/adenovirus E1B 19kDa interacting protein 3-like | 0.0241857 |
| CXCL8 | chemokine (C-X-C motif) ligand 8 | 0.0235245 |
| RACK1 | receptor for activated C kinase 1 | 0.0226863 |
| RPS12 | ribosomal protein S12 | 0.0209674 |
| WDR43 | WD repeat domain 43 | 0.0208824 |
| TMSB4X | thymosin beta 4, X-linked | 0.0206034 |
| NPM1 | nucleophosmin (nucleolar phosphoprotein B23, numatrin) | 0.0198324 |
| EEF1A1 | eukaryotic translation elongation factor 1 alpha 1 | 0.0188169 |
| RSRC2 | arginine/serine-rich coiled-coil 2 | 0.018148 |
| SERINC1 | serine incorporator 1 | 0.0181005 |
| TAF1D | TATA box binding protein (TBP)-associated factor, RNA polymerase I, D, 41kDa | 0.0180034 |
| GLS2 | glutaminase 2 (liver, mitochondrial) | 0.017899 |
| ASAP2 | ArfGAP with SH3 domain, ankyrin repeat and PH domain 2 | 0.0175607 |
| ERC1 | ELKS/RAB6-interacting/CAST family member 1 | 0.0174791 |
| TNFRSF10D | tumor necrosis factor receptor superfamily, member 10d, decoy with truncated death domain | 0.0172125 |
| CAMTA1 | calmodulin binding transcription activator 1 | 0.0172099 |
| ATP13A3 | ATPase type 13A3 | 0.0169052 |
| RABGEF1 | RAB guanine nucleotide exchange factor (GEF) 1 | 0.0168803 |
| CTNNA1 | catenin (cadherin-associated protein), alpha 1, 102kDa | 0.0168094 |
| PSME4 | proteasome (prosome, macropain) activator subunit 4 | 0.016433 |
| RASA2 | RAS p21 protein activator 2 | 0.0156265 |
| ZEB1 | zinc finger E-box binding homeobox 1 | 0.0152755 |
| TCEA1 | transcription elongation factor A (SII), 1 | 0.0149621 |
| KCNMA1 | potassium channel, calcium activated large conductance subfamily M alpha, member 1 | 0.0146371 |
| TBC1D22A | TBC1 domain family, member 22A | 0.0145642 |
| KPNA4 | karyopherin alpha 4 (importin alpha 3) | 0.014325 |
| EIF1 | eukaryotic translation initiation factor 1 | 0.0143083 |
| RPS8 | ribosomal protein S8 | 0.0142767 |
| VMP1 | vacuole membrane protein 1 | 0.0140396 |
| CRY1 | cryptochrome circadian clock 1 | 0.0138256 |
| SLC16A1 | solute carrier family 16 (monocarboxylate transporter), member 1 | 0.0133969 |
| RECQL | RecQ helicase-like | 0.0133857 |
| FER | fer (fps/fes related) tyrosine kinase | 0.01316 |
| DNAJC25 | DnaJ (Hsp40) homolog, subfamily C , member 25 | 0.0131223 |
| RPS6KA3 | ribosomal protein S6 kinase, 90kDa, polypeptide 3 | 0.0129683 |
| TRA2B | transformer 2 beta homolog (Drosophila) | 0.0129072 |
| KIAA1958 | KIAA1958 | 0.0128256 |
| NEK7 | NIMA-related kinase 7 | 0.0127614 |
| EXOC6B | exocyst complex component 6B | 0.0125368 |
| SBF2 | SET binding factor 2 | 0.0125262 |
| ASCC3 | activating signal cointegrator 1 complex subunit 3 | 0.0124483 |
| SEC61A1 | Sec61 alpha 1 subunit (S. cerevisiae) | 0.0123664 |
| ZBTB21 | zinc finger and BTB domain containing 21 | 0.012273 |
| TRIO | trio Rho guanine nucleotide exchange factor | 0.0122287 |
| RTN4 | reticulon 4 | 0.0121393 |
| GMDS | GDP-mannose 4,6-dehydratase | 0.0121342 |
| PPME1 | protein phosphatase methylesterase 1 | 0.012094 |
| DHX9 | DEAH (Asp-Glu-Ala-His) box helicase 9 | 0.0120011 |
| RNF145 | ring finger protein 145 | 0.0119117 |
| ANO6 | anoctamin 6 | 0.0119019 |
| TMEM167A | transmembrane protein 167A | 0.0118638 |
| PNN | pinin, desmosome associated protein | 0.0117949 |
| TFRC | transferrin receptor | 0.0117774 |
| ASH1L | ash1 (absent, small, or homeotic)-like (Drosophila) | 0.0116825 |
| SLCO1B3 | solute carrier organic anion transporter family, member 1B3 | 0.0116537 |
| MAN1A2 | mannosidase, alpha, class 1A, member 2 | 0.0115827 |
| EZR | ezrin | 0.0115055 |
| SMAP1 | small ArfGAP 1 | 0.0112287 |
| YWHAE | tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, epsilon | 0.0110728 |
| PHF3 | PHD finger protein 3 | 0.0110194 |
| BRD2 | bromodomain containing 2 | 0.010914 |
| AHCTF1 | AT hook containing transcription factor 1 | 0.0107566 |
| MGAT5 | mannosyl (alpha-1,6-)-glycoprotein beta-1,6-N-acetyl-glucosaminyltransferase | 0.0106373 |
| ADARB1 | adenosine deaminase, RNA-specific, B1 | 0.0106293 |
| ALG13 | ALG13, UDP-N-acetylglucosaminyltransferase subunit | 0.0106117 |
| SF1 | splicing factor 1 | 0.0104791 |
| POU2F1 | POU class 2 homeobox 1 | 0.010453 |
| TMEM41B | transmembrane protein 41B | 0.0104285 |
| NUP58 | nucleoporin 58 | 0.010387 |
| RALGAPA2 | Ral GTPase activating protein, alpha subunit 2 (catalytic) | 0.0103772 |
| POM121 | POM121 transmembrane nucleoporin | 0.0102168 |
| RAPGEF6 | Rap guanine nucleotide exchange factor (GEF) 6 | 0.0101532 |
| RPN1 | ribophorin I | 0.0100884 |
| EIF3E | eukaryotic translation initiation factor 3, subunit E | 0.0100617 |
| SERBP1 | SERPINE1 mRNA binding protein 1 | 0.0100298 |
| ETS1 | v-ets avian erythroblastosis virus E26 oncogene homolog 1 | 0.00999932 |
| HIBADH | 3-hydroxyisobutyrate dehydrogenase | 0.00998105 |
| PYGB | phosphorylase, glycogen; brain | 0.00993918 |
| FOS | FBJ murine osteosarcoma viral oncogene homolog | 0.00980972 |
| SENP5 | SUMO1/sentrin specific peptidase 5 | 0.00976557 |
| SSR3 | signal sequence receptor, gamma (translocon-associated protein gamma) | 0.00958369 |
| DICER1 | dicer 1, ribonuclease type III | 0.0095646 |
| ABI1 | abl-interactor 1 | 0.00942485 |
| BCLAF1 | BCL2-associated transcription factor 1 | 0.0093728 |
| TOP2B | topoisomerase (DNA) II beta 180kDa | 0.00937141 |
| AGTPBP1 | ATP/GTP binding protein 1 | 0.00933324 |
| AREG | amphiregulin | 0.00930405 |
| Symbol | Name | Standardized Value |
|---|---|---|
| GAPDH | glyceraldehyde-3-phosphate dehydrogenase | -0.288746 |
| PTMA | prothymosin, alpha | -0.269948 |
| VIM | vimentin | -0.218995 |
| MT2A | metallothionein 2A | -0.195167 |
| CD44 | CD44 molecule (Indian blood group) | -0.13357 |
| SEMA3A | sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3A | -0.111326 |
| TP63 | tumor protein p63 | -0.109136 |
| HSP90AA1 | heat shock protein 90kDa alpha (cytosolic), class A member 1 | -0.0993086 |
| PABPC1 | poly(A) binding protein, cytoplasmic 1 | -0.0992855 |
| DST | dystonin | -0.0794476 |
| MT1E | metallothionein 1E | -0.0699552 |
| FTL | ferritin, light polypeptide | -0.0665802 |
| RASSF8 | Ras association (RalGDS/AF-6) domain family (N-terminal) member 8 | -0.0654873 |
| TXNIP | thioredoxin interacting protein | -0.0630566 |
| TMSB10 | thymosin beta 10 | -0.0621925 |
| NFAT5 | nuclear factor of activated T-cells 5, tonicity-responsive | -0.060645 |
| EIF2AK2 | eukaryotic translation initiation factor 2-alpha kinase 2 | -0.0585405 |
| RNF213 | ring finger protein 213 | -0.0584753 |
| WARS1 | tryptophanyl-tRNA synthetase 1 | -0.0569616 |
| PGK1 | phosphoglycerate kinase 1 | -0.0562904 |
| RIGI | RNA sensor RIG-I | -0.0546269 |
| ACTG1 | actin gamma 1 | -0.0543457 |
| NUCKS1 | nuclear casein kinase and cyclin-dependent kinase substrate 1 | -0.0540033 |
| HLA-B | major histocompatibility complex, class I, B | -0.0521077 |
| PTPRF | protein tyrosine phosphatase, receptor type, F | -0.0501122 |
| STAT1 | signal transducer and activator of transcription 1, 91kDa | -0.049878 |
| DLG1 | discs, large homolog 1 (Drosophila) | -0.0489471 |
| SERPINE1 | serpin peptidase inhibitor, clade E (nexin, plasminogen activator inhibitor type 1), member 1 | -0.0489332 |
| WSB1 | WD repeat and SOCS box containing 1 | -0.0489163 |
| HSP90B1 | heat shock protein 90kDa beta (Grp94), member 1 | -0.0487066 |
| PSD3 | pleckstrin and Sec7 domain containing 3 | -0.0459278 |
| SERPINA3 | serpin peptidase inhibitor, clade A (alpha-1 antiproteinase, antitrypsin), member 3 | -0.0458447 |
| IL1RAPL1 | interleukin 1 receptor accessory protein-like 1 | -0.0450955 |
| TOP2A | topoisomerase (DNA) II alpha 170kDa | -0.0450872 |
| TSC22D1 | TSC22 domain family, member 1 | -0.0448682 |
| ERO1A | endoplasmic reticulum oxidoreductase 1 alpha | -0.0446663 |
| EPHA4 | EPH receptor A4 | -0.0437769 |
| ENO2 | enolase 2 (gamma, neuronal) | -0.0428925 |
| CADM2 | cell adhesion molecule 2 | -0.0418894 |
| SLC38A2 | solute carrier family 38, member 2 | -0.0416162 |
| SRGAP1 | SLIT-ROBO Rho GTPase activating protein 1 | -0.0408944 |
| RPL35A | ribosomal protein L35a | -0.0405636 |
| ZMYND8 | zinc finger, MYND-type containing 8 | -0.0404808 |
| AHNAK | AHNAK nucleoprotein | -0.0404587 |
| IFITM1 | interferon induced transmembrane protein 1 | -0.0402654 |
| DPYD | dihydropyrimidine dehydrogenase | -0.0401951 |
| MT1X | metallothionein 1X | -0.0390434 |
| CALR | calreticulin | -0.0390332 |
| PARP14 | poly (ADP-ribose) polymerase family, member 14 | -0.0388758 |
| VCL | vinculin | -0.038444 |
| ARL6IP1 | ADP-ribosylation factor-like 6 interacting protein 1 | -0.0384424 |
| ECE1 | endothelin converting enzyme 1 | -0.037652 |
| ENO1 | enolase 1, (alpha) | -0.0372864 |
| SEMA3C | sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3C | -0.0369328 |
| DDX60L | DEAD (Asp-Glu-Ala-Asp) box polypeptide 60-like | -0.0365988 |
| EHBP1 | EH domain binding protein 1 | -0.036385 |
| IFIT2 | interferon-induced protein with tetratricopeptide repeats 2 | -0.0357765 |
| IMMP2L | IMP2 inner mitochondrial membrane peptidase-like (S. cerevisiae) | -0.035632 |
| IFI6 | interferon, alpha-inducible protein 6 | -0.0352577 |
| SLC25A36 | solute carrier family 25 (pyrimidine nucleotide carrier), member 36 | -0.0350249 |
| ADGRG6 | adhesion G protein-coupled receptor G6 | -0.0347829 |
| IFIH1 | interferon induced with helicase C domain 1 | -0.0345546 |
| SMURF2 | SMAD specific E3 ubiquitin protein ligase 2 | -0.0340834 |
| SCD | stearoyl-CoA desaturase (delta-9-desaturase) | -0.0337416 |
| SMURF1 | SMAD specific E3 ubiquitin protein ligase 1 | -0.0331382 |
| PHLDB2 | pleckstrin homology-like domain, family B, member 2 | -0.0324432 |
| KPNB1 | karyopherin (importin) beta 1 | -0.0324163 |
| PHLDA1 | pleckstrin homology-like domain, family A, member 1 | -0.0321669 |
| RPS19 | ribosomal protein S19 | -0.0319756 |
| BCAR3 | breast cancer anti-estrogen resistance 3 | -0.0319638 |
| MBNL2 | muscleblind-like splicing regulator 2 | -0.0318627 |
| PTPN12 | protein tyrosine phosphatase, non-receptor type 12 | -0.0318325 |
| TPM4 | tropomyosin 4 | -0.0317429 |
| PKM | pyruvate kinase, muscle | -0.0313139 |
| NCEH1 | neutral cholesterol ester hydrolase 1 | -0.0310402 |
| WNK1 | WNK lysine deficient protein kinase 1 | -0.0305051 |
| HMGA1 | high mobility group AT-hook 1 | -0.0304411 |
| ZDHHC14 | zinc finger, DHHC-type containing 14 | -0.0303903 |
| TRIP12 | thyroid hormone receptor interactor 12 | -0.0298762 |
| SP100 | SP100 nuclear antigen | -0.029872 |
| VDAC1 | voltage-dependent anion channel 1 | -0.0297126 |
| RPL8 | ribosomal protein L8 | -0.0295307 |
| XPO1 | exportin 1 | -0.0290181 |
| S100A10 | S100 calcium binding protein A10 | -0.0290141 |
| GNB1 | guanine nucleotide binding protein (G protein), beta polypeptide 1 | -0.0287671 |
| CENPF | centromere protein F, 350/400kDa | -0.0285701 |
| NFKBIA | nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor, alpha | -0.0285104 |
| TAF15 | TAF15 RNA polymerase II, TATA box binding protein (TBP)-associated factor, 68kDa | -0.0284365 |
| SRRM2 | serine/arginine repetitive matrix 2 | -0.0282259 |
| ANXA2 | annexin A2 | -0.028219 |
| BIRC3 | baculoviral IAP repeat containing 3 | -0.0281191 |
| LRCH3 | leucine-rich repeats and calponin homology (CH) domain containing 3 | -0.0279734 |
| RAD51B | RAD51 paralog B | -0.0278496 |
| KMT2A | lysine (K)-specific methyltransferase 2A | -0.0276896 |
| CDK6 | cyclin-dependent kinase 6 | -0.0274829 |
| EGR1 | early growth response 1 | -0.0271722 |
| FMNL2 | formin-like 2 | -0.0268682 |
| SDC4 | syndecan 4 | -0.0267168 |
| GLG1 | golgi glycoprotein 1 | -0.0266105 |
| GCLM | glutamate-cysteine ligase, modifier subunit | -0.0265838 |
