| Dataset | Tahoe Therapeutics Tahoe 100M Perturbation Atlas |
| Category | transcriptomics |
| Type | cell type |
| Description | Erlotinib perturbation in NCI-H1573 cell line (Tahoe Therapeutics) |
| Similar Terms | |
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200 genes differentially expressed following the Erlotinib_NCI-H1573 drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| TXNRD1 | thioredoxin reductase 1 | 0.184878 |
| LRP1B | low density lipoprotein receptor-related protein 1B | 0.15934 |
| ERO1A | endoplasmic reticulum oxidoreductase 1 alpha | 0.141021 |
| FTH1 | ferritin, heavy polypeptide 1 | 0.130776 |
| AKR1C1 | aldo-keto reductase family 1, member C1 | 0.106717 |
| FAM13A | family with sequence similarity 13, member A | 0.0755707 |
| GCLC | glutamate-cysteine ligase, catalytic subunit | 0.0645446 |
| FTL | ferritin, light polypeptide | 0.0629145 |
| NAMPT | nicotinamide phosphoribosyltransferase | 0.0554993 |
| SLC38A1 | solute carrier family 38, member 1 | 0.0513454 |
| PDE4D | phosphodiesterase 4D, cAMP-specific | 0.0388321 |
| CPE | carboxypeptidase E | 0.0365345 |
| CYP24A1 | cytochrome P450, family 24, subfamily A, polypeptide 1 | 0.0356011 |
| NR3C1 | nuclear receptor subfamily 3, group C, member 1 (glucocorticoid receptor) | 0.0354763 |
| B2M | beta-2-microglobulin | 0.0349741 |
| RNF145 | ring finger protein 145 | 0.0340908 |
| GBE1 | glucan (1,4-alpha-), branching enzyme 1 | 0.0333459 |
| LIMCH1 | LIM and calponin homology domains 1 | 0.0322482 |
| YBX3 | Y box binding protein 3 | 0.0305293 |
| CAV1 | caveolin 1, caveolae protein, 22kDa | 0.0291514 |
| BIRC3 | baculoviral IAP repeat containing 3 | 0.0285688 |
| ZNF292 | zinc finger protein 292 | 0.0274953 |
| ALCAM | activated leukocyte cell adhesion molecule | 0.0264496 |
| FHIP1A | FHF complex subunit HOOK interacting protein 1A | 0.0262735 |
| TPD52 | tumor protein D52 | 0.0260911 |
| CLU | clusterin | 0.0259403 |
| TENT5A | terminal nucleotidyltransferase 5A | 0.0256427 |
| ARRDC3 | arrestin domain containing 3 | 0.0252269 |
| CCNL1 | cyclin L1 | 0.0251306 |
| REL | v-rel avian reticuloendotheliosis viral oncogene homolog | 0.0244417 |
| CAMTA1 | calmodulin binding transcription activator 1 | 0.0236693 |
| TAF1D | TATA box binding protein (TBP)-associated factor, RNA polymerase I, D, 41kDa | 0.0230847 |
| PIR | pirin (iron-binding nuclear protein) | 0.0226729 |
| TMF1 | TATA element modulatory factor 1 | 0.0222427 |
| SPTSSA | serine palmitoyltransferase, small subunit A | 0.0220256 |
| FNDC3B | fibronectin type III domain containing 3B | 0.0217995 |
| GCLM | glutamate-cysteine ligase, modifier subunit | 0.0215381 |
| CPEB2 | cytoplasmic polyadenylation element binding protein 2 | 0.0204497 |
| KDM5B | lysine (K)-specific demethylase 5B | 0.020122 |
| ZBTB20 | zinc finger and BTB domain containing 20 | 0.0198863 |
| ARID2 | AT rich interactive domain 2 (ARID, RFX-like) | 0.0198319 |
| TKT | transketolase | 0.0194109 |
| KYNU | kynureninase | 0.0190692 |
| GPRC5A | G protein-coupled receptor, class C, group 5, member A | 0.0190163 |
| LITAF | lipopolysaccharide-induced TNF factor | 0.0188664 |
| TMTC2 | transmembrane and tetratricopeptide repeat containing 2 | 0.0188192 |
| RPS6 | ribosomal protein S6 | 0.0187661 |
| ASCC3 | activating signal cointegrator 1 complex subunit 3 | 0.0185971 |
| AKAP9 | A kinase (PRKA) anchor protein 9 | 0.0184901 |
| MXI1 | MAX interactor 1, dimerization protein | 0.0180495 |
| MGAT4C | MGAT4 family, member C | 0.017724 |
| ROBO1 | roundabout, axon guidance receptor, homolog 1 (Drosophila) | 0.0176093 |
| RPL11 | ribosomal protein L11 | 0.0172841 |
| KMT2C | lysine (K)-specific methyltransferase 2C | 0.0171112 |
| NQO1 | NAD(P)H dehydrogenase, quinone 1 | 0.0169991 |
| DNAJC3 | DnaJ (Hsp40) homolog, subfamily C, member 3 | 0.0168803 |
| UGDH | UDP-glucose 6-dehydrogenase | 0.0162042 |
| PER2 | period circadian clock 2 | 0.0161358 |
| PDK3 | pyruvate dehydrogenase kinase, isozyme 3 | 0.0159937 |
| AHR | aryl hydrocarbon receptor | 0.0159191 |
| THOC2 | THO complex 2 | 0.0159002 |
| KDM2A | lysine (K)-specific demethylase 2A | 0.0156775 |
| SLC7A11 | solute carrier family 7 (anionic amino acid transporter light chain, xc- system), member 11 | 0.0151634 |
| HILPDA | hypoxia inducible lipid droplet-associated | 0.0148264 |
| CYP1B1 | cytochrome P450, family 1, subfamily B, polypeptide 1 | 0.014722 |
| IRS2 | insulin receptor substrate 2 | 0.0147009 |
| MLF1 | myeloid leukemia factor 1 | 0.0145951 |
| RPLP0 | ribosomal protein, large, P0 | 0.0144903 |
| SF3B1 | splicing factor 3b, subunit 1, 155kDa | 0.0144037 |
| RBPJ | recombination signal binding protein for immunoglobulin kappa J region | 0.0142188 |
| SLC6A6 | solute carrier family 6 (neurotransmitter transporter), member 6 | 0.0141148 |
| BCL9L | B-cell CLL/lymphoma 9-like | 0.0139301 |
| MGAT5 | mannosyl (alpha-1,6-)-glycoprotein beta-1,6-N-acetyl-glucosaminyltransferase | 0.0138396 |
| DENND4A | DENN/MADD domain containing 4A | 0.0137773 |
| MAP3K4 | mitogen-activated protein kinase kinase kinase 4 | 0.013541 |
| SQSTM1 | sequestosome 1 | 0.0133334 |
| RLF | rearranged L-myc fusion | 0.0133017 |
| UBAC2 | UBA domain containing 2 | 0.0132323 |
| ABCC2 | ATP-binding cassette, sub-family C (CFTR/MRP), member 2 | 0.0131476 |
| TMBIM6 | transmembrane BAX inhibitor motif containing 6 | 0.0129696 |
| ANKRD12 | ankyrin repeat domain 12 | 0.0129562 |
| ZBTB1 | zinc finger and BTB domain containing 1 | 0.0129092 |
| DSPP | dentin sialophosphoprotein | 0.0127266 |
| ZMYND8 | zinc finger, MYND-type containing 8 | 0.0126781 |
| TPR | translocated promoter region, nuclear basket protein | 0.0125375 |
| NR4A2 | nuclear receptor subfamily 4, group A, member 2 | 0.0124903 |
| KIAA0319 | KIAA0319 | 0.0124333 |
| ADGRF1 | adhesion G protein-coupled receptor F1 | 0.0122387 |
| BBX | bobby sox homolog (Drosophila) | 0.0120237 |
| GPHN | gephyrin | 0.0120138 |
| HSPD1 | heat shock 60kDa protein 1 (chaperonin) | 0.0120032 |
| SEC31A | SEC31 homolog A (S. cerevisiae) | 0.0119652 |
| EGLN3 | egl-9 family hypoxia-inducible factor 3 | 0.0119531 |
| NGLY1 | N-glycanase 1 | 0.0118402 |
| TOMM20 | translocase of outer mitochondrial membrane 20 homolog (yeast) | 0.0118396 |
| BRWD1 | bromodomain and WD repeat domain containing 1 | 0.0117814 |
| MSMO1 | methylsterol monooxygenase 1 | 0.0117089 |
| PTGS2 | prostaglandin-endoperoxide synthase 2 (prostaglandin G/H synthase and cyclooxygenase) | 0.0117059 |
| TTC3 | tetratricopeptide repeat domain 3 | 0.011683 |
| GSTP1 | glutathione S-transferase pi 1 | 0.0116564 |
| Symbol | Name | Standardized Value |
|---|---|---|
| GAPDH | glyceraldehyde-3-phosphate dehydrogenase | -0.166946 |
| LAMC2 | laminin, gamma 2 | -0.130896 |
| THSD4 | thrombospondin, type I, domain containing 4 | -0.121035 |
| MCL1 | myeloid cell leukemia 1 | -0.100271 |
| TMSB10 | thymosin beta 10 | -0.0997615 |
| ITGB1 | integrin, beta 1 (fibronectin receptor, beta polypeptide, antigen CD29 includes MDF2, MSK12) | -0.0893958 |
| PKM | pyruvate kinase, muscle | -0.0888206 |
| PITPNC1 | phosphatidylinositol transfer protein, cytoplasmic 1 | -0.0876597 |
| ACTG1 | actin gamma 1 | -0.0839937 |
| CEACAM6 | carcinoembryonic antigen-related cell adhesion molecule 6 (non-specific cross reacting antigen) | -0.0833026 |
| UBC | ubiquitin C | -0.0733792 |
| KCNMA1 | potassium channel, calcium activated large conductance subfamily M alpha, member 1 | -0.0730516 |
| MT2A | metallothionein 2A | -0.0712848 |
| STC1 | stanniocalcin 1 | -0.069315 |
| SLTM | SAFB-like, transcription modulator | -0.0692344 |
| ASPH | aspartate beta-hydroxylase | -0.0684328 |
| AHNAK | AHNAK nucleoprotein | -0.068088 |
| SEMA3C | sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3C | -0.0659257 |
| PTPRM | protein tyrosine phosphatase, receptor type, M | -0.0649 |
| ANXA2 | annexin A2 | -0.0646244 |
| PHLDA1 | pleckstrin homology-like domain, family A, member 1 | -0.0599434 |
| S100A10 | S100 calcium binding protein A10 | -0.0598367 |
| HERC4 | HECT and RLD domain containing E3 ubiquitin protein ligase 4 | -0.0578736 |
| GRAMD1B | GRAM domain containing 1B | -0.0563615 |
| LAMA4 | laminin, alpha 4 | -0.054584 |
| SAMD4A | sterile alpha motif domain containing 4A | -0.053855 |
| NDRG1 | N-myc downstream regulated 1 | -0.0534789 |
| ENO1 | enolase 1, (alpha) | -0.0527392 |
| SCEL | sciellin | -0.0514152 |
| OSMR | oncostatin M receptor | -0.0513797 |
| SHANK2 | SH3 and multiple ankyrin repeat domains 2 | -0.0500976 |
| PTMA | prothymosin, alpha | -0.0481105 |
| EGFR | epidermal growth factor receptor | -0.0471412 |
| BCAR3 | breast cancer anti-estrogen resistance 3 | -0.0471307 |
| CEACAM5 | carcinoembryonic antigen-related cell adhesion molecule 5 | -0.0438385 |
| MAP3K20 | mitogen-activated protein kinase kinase kinase 20 | -0.0430727 |
| KRT18 | keratin 18, type I | -0.0428499 |
| HSPA5 | heat shock 70kDa protein 5 (glucose-regulated protein, 78kDa) | -0.0413808 |
| ITGA2 | integrin, alpha 2 (CD49B, alpha 2 subunit of VLA-2 receptor) | -0.0404545 |
| CDCP1 | CUB domain containing protein 1 | -0.0404503 |
| ELL2 | elongation factor, RNA polymerase II, 2 | -0.0402517 |
| DOCK5 | dedicator of cytokinesis 5 | -0.039848 |
| LOC112694756 | uncharaterized LOC112694756 | -0.0397003 |
| RPS27A | ribosomal protein S27a | -0.0392606 |
| NABP1 | nucleic acid binding protein 1 | -0.0386735 |
| AKAP13 | A kinase (PRKA) anchor protein 13 | -0.0380736 |
| PPP6R3 | protein phosphatase 6, regulatory subunit 3 | -0.036375 |
| CALM1 | calmodulin 1 (phosphorylase kinase, delta) | -0.0362803 |
| ENSA | endosulfine alpha | -0.0360107 |
| CD55 | CD55 molecule, decay accelerating factor for complement (Cromer blood group) | -0.0357594 |
| SRGAP1 | SLIT-ROBO Rho GTPase activating protein 1 | -0.0356352 |
| PDLIM5 | PDZ and LIM domain 5 | -0.0352661 |
| TOP1 | topoisomerase (DNA) I | -0.0352548 |
| LAMB3 | laminin, beta 3 | -0.034783 |
| MYO1D | myosin ID | -0.0342544 |
| AGAP1 | ArfGAP with GTPase domain, ankyrin repeat and PH domain 1 | -0.034036 |
| EGR1 | early growth response 1 | -0.0337628 |
| KRT8 | keratin 8, type II | -0.0332042 |
| MACF1 | microtubule-actin crosslinking factor 1 | -0.0328798 |
| TANC2 | tetratricopeptide repeat, ankyrin repeat and coiled-coil containing 2 | -0.0327972 |
| VCL | vinculin | -0.0325386 |
| SEMA4B | sema domain, immunoglobulin domain (Ig), transmembrane domain (TM) and short cytoplasmic domain, (semaphorin) 4B | -0.0323193 |
| PARD3 | par-3 family cell polarity regulator | -0.0322781 |
| FZR1 | fizzy/cell division cycle 20 related 1 (Drosophila) | -0.0322082 |
| ERRFI1 | ERBB receptor feedback inhibitor 1 | -0.031932 |
| USP53 | ubiquitin specific peptidase 53 | -0.0317077 |
| KRT7 | keratin 7, type II | -0.0316065 |
| TPT1 | tumor protein, translationally-controlled 1 | -0.0315191 |
| PGK1 | phosphoglycerate kinase 1 | -0.0313988 |
| PLEC | plectin | -0.031385 |
| PYGL | phosphorylase, glycogen, liver | -0.0313842 |
| CCND1 | cyclin D1 | -0.0313702 |
| LPP | LIM domain containing preferred translocation partner in lipoma | -0.031288 |
| BMAL2 | basic helix-loop-helix ARNT like 2 | -0.0304387 |
| GNB1 | guanine nucleotide binding protein (G protein), beta polypeptide 1 | -0.0303255 |
| CSNK1E | casein kinase 1, epsilon | -0.030224 |
| MYL12A | myosin, light chain 12A, regulatory, non-sarcomeric | -0.0301918 |
| MYO1E | myosin IE | -0.03013 |
| RASA2 | RAS p21 protein activator 2 | -0.0297406 |
| MYH9 | myosin, heavy chain 9, non-muscle | -0.0296984 |
| ARPC2 | actin related protein 2/3 complex, subunit 2, 34kDa | -0.0294408 |
| PABPC1 | poly(A) binding protein, cytoplasmic 1 | -0.0293914 |
| TRIP12 | thyroid hormone receptor interactor 12 | -0.0292393 |
| ATP11A | ATPase, class VI, type 11A | -0.0289763 |
| INTS6 | integrator complex subunit 6 | -0.0283315 |
| CSNK1A1 | casein kinase 1, alpha 1 | -0.0282579 |
| ABL2 | ABL proto-oncogene 2, non-receptor tyrosine kinase | -0.0280745 |
| CAPN2 | calpain 2, (m/II) large subunit | -0.0278493 |
| CEMIP | cell migration inducing protein, hyaluronan binding | -0.0271552 |
| MAML3 | mastermind-like 3 (Drosophila) | -0.0271297 |
| RTN4 | reticulon 4 | -0.0270419 |
| IFI6 | interferon, alpha-inducible protein 6 | -0.0266697 |
| LMO7 | LIM domain 7 | -0.0263718 |
| TPM4 | tropomyosin 4 | -0.0262892 |
| LRRFIP1 | leucine rich repeat (in FLII) interacting protein 1 | -0.0262286 |
| ATP2B1 | ATPase, Ca++ transporting, plasma membrane 1 | -0.0261264 |
| SRRM2 | serine/arginine repetitive matrix 2 | -0.0259533 |
| LGALS12 | lectin, galactoside-binding, soluble, 12 | -0.0259277 |
| SMAD3 | SMAD family member 3 | -0.0259138 |
| JMJD1C | jumonji domain containing 1C | -0.0257919 |
