| Dataset | Tahoe Therapeutics Tahoe 100M Perturbation Atlas |
| Category | transcriptomics |
| Type | cell type |
| Description | Erlotinib perturbation in NCI-H1792 cell line (Tahoe Therapeutics) |
| Similar Terms | |
| Downloads & Tools |
200 genes differentially expressed following the Erlotinib_NCI-H1792 drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| PDE4D | phosphodiesterase 4D, cAMP-specific | 0.102581 |
| RBMS3 | RNA binding motif, single stranded interacting protein 3 | 0.0959462 |
| CXCL8 | chemokine (C-X-C motif) ligand 8 | 0.0700086 |
| GBE1 | glucan (1,4-alpha-), branching enzyme 1 | 0.0699164 |
| GPRC5A | G protein-coupled receptor, class C, group 5, member A | 0.0669916 |
| HSP90AB1 | heat shock protein 90kDa alpha (cytosolic), class B member 1 | 0.0609633 |
| EFNA5 | ephrin-A5 | 0.0597325 |
| ANXA1 | annexin A1 | 0.0580431 |
| TAS2R14 | taste receptor, type 2, member 14 | 0.0506122 |
| AKAP12 | A kinase (PRKA) anchor protein 12 | 0.0499222 |
| AKAP9 | A kinase (PRKA) anchor protein 9 | 0.0429628 |
| CD44 | CD44 molecule (Indian blood group) | 0.0429472 |
| AGAP1 | ArfGAP with GTPase domain, ankyrin repeat and PH domain 1 | 0.0422143 |
| USP34 | ubiquitin specific peptidase 34 | 0.041598 |
| GPHN | gephyrin | 0.0414626 |
| NHS | Nance-Horan syndrome (congenital cataracts and dental anomalies) | 0.0385324 |
| UACA | uveal autoantigen with coiled-coil domains and ankyrin repeats | 0.0382433 |
| PRELID2 | PRELI domain containing 2 | 0.0376185 |
| KCNMA1 | potassium channel, calcium activated large conductance subfamily M alpha, member 1 | 0.0368204 |
| NAV2 | neuron navigator 2 | 0.0360455 |
| SEC31A | SEC31 homolog A (S. cerevisiae) | 0.0353178 |
| FNDC3B | fibronectin type III domain containing 3B | 0.0351914 |
| PTPRR | protein tyrosine phosphatase, receptor type, R | 0.034541 |
| ANO6 | anoctamin 6 | 0.0337025 |
| TMSB4X | thymosin beta 4, X-linked | 0.0336053 |
| DLG1 | discs, large homolog 1 (Drosophila) | 0.0334452 |
| ATXN1 | ataxin 1 | 0.0332271 |
| TMTC2 | transmembrane and tetratricopeptide repeat containing 2 | 0.0330704 |
| NBAS | neuroblastoma amplified sequence | 0.0327314 |
| MAML2 | mastermind-like 2 (Drosophila) | 0.032371 |
| NCOA7 | nuclear receptor coactivator 7 | 0.0316192 |
| TBC1D5 | TBC1 domain family, member 5 | 0.0312893 |
| SCFD1 | sec1 family domain containing 1 | 0.0304101 |
| FAM13A | family with sequence similarity 13, member A | 0.0294759 |
| LRRC49 | leucine rich repeat containing 49 | 0.0292591 |
| GOLGB1 | golgin B1 | 0.0291415 |
| MYOF | myoferlin | 0.0290428 |
| SLC41A2 | solute carrier family 41 (magnesium transporter), member 2 | 0.0288313 |
| TRIO | trio Rho guanine nucleotide exchange factor | 0.0282785 |
| NUS1 | nuclear undecaprenyl pyrophosphate synthase 1 homolog (S. cerevisiae) | 0.028098 |
| ASCC3 | activating signal cointegrator 1 complex subunit 3 | 0.0279303 |
| RPS24 | ribosomal protein S24 | 0.0278884 |
| RPLP0 | ribosomal protein, large, P0 | 0.0269886 |
| ZCCHC7 | zinc finger, CCHC domain containing 7 | 0.0269133 |
| MON2 | MON2 homolog (S. cerevisiae) | 0.0268588 |
| GPC6 | glypican 6 | 0.026365 |
| RACK1 | receptor for activated C kinase 1 | 0.0261614 |
| ZSWIM6 | zinc finger, SWIM-type containing 6 | 0.0256014 |
| TXNRD1 | thioredoxin reductase 1 | 0.0254877 |
| RUNX1 | runt-related transcription factor 1 | 0.0254848 |
| ZBTB20 | zinc finger and BTB domain containing 20 | 0.0254146 |
| ZNF638 | zinc finger protein 638 | 0.0250847 |
| RB1CC1 | RB1-inducible coiled-coil 1 | 0.0247135 |
| BZW1 | basic leucine zipper and W2 domains 1 | 0.0245193 |
| FER | fer (fps/fes related) tyrosine kinase | 0.0244897 |
| BCAS3 | breast carcinoma amplified sequence 3 | 0.0243547 |
| EXOC6B | exocyst complex component 6B | 0.024184 |
| EXOC4 | exocyst complex component 4 | 0.0241137 |
| LIMCH1 | LIM and calponin homology domains 1 | 0.024095 |
| MAGI2 | membrane associated guanylate kinase, WW and PDZ domain containing 2 | 0.0240306 |
| LDHA | lactate dehydrogenase A | 0.02395 |
| DENND1A | DENN/MADD domain containing 1A | 0.0236912 |
| FBXL13 | F-box and leucine-rich repeat protein 13 | 0.0236808 |
| GMDS | GDP-mannose 4,6-dehydratase | 0.0235614 |
| VPS13B | vacuolar protein sorting 13 homolog B (yeast) | 0.023418 |
| TBC1D22A | TBC1 domain family, member 22A | 0.0229226 |
| HERC4 | HECT and RLD domain containing E3 ubiquitin protein ligase 4 | 0.0227952 |
| HSPD1 | heat shock 60kDa protein 1 (chaperonin) | 0.0227657 |
| RARB | retinoic acid receptor, beta | 0.0226863 |
| CACNA2D3 | calcium channel, voltage-dependent, alpha 2/delta subunit 3 | 0.0225433 |
| ALCAM | activated leukocyte cell adhesion molecule | 0.0225247 |
| NBEAL1 | neurobeachin-like 1 | 0.0225003 |
| PTPRM | protein tyrosine phosphatase, receptor type, M | 0.0224009 |
| MIB1 | mindbomb E3 ubiquitin protein ligase 1 | 0.0219691 |
| RPS6 | ribosomal protein S6 | 0.0218854 |
| ANKIB1 | ankyrin repeat and IBR domain containing 1 | 0.0217703 |
| SEPTIN9 | septin 9 | 0.021673 |
| BIRC3 | baculoviral IAP repeat containing 3 | 0.0216022 |
| MBD5 | methyl-CpG binding domain protein 5 | 0.021574 |
| IL1RAP | interleukin 1 receptor accessory protein | 0.0215282 |
| BPTF | bromodomain PHD finger transcription factor | 0.0215246 |
| TAF1D | TATA box binding protein (TBP)-associated factor, RNA polymerase I, D, 41kDa | 0.0211214 |
| MYO9A | myosin IXA | 0.0207702 |
| ITPR2 | inositol 1,4,5-trisphosphate receptor, type 2 | 0.0207518 |
| PHF3 | PHD finger protein 3 | 0.0206446 |
| ARHGAP24 | Rho GTPase activating protein 24 | 0.0205239 |
| KMT2C | lysine (K)-specific methyltransferase 2C | 0.0204869 |
| HIVEP2 | human immunodeficiency virus type I enhancer binding protein 2 | 0.0204499 |
| PTPRK | protein tyrosine phosphatase, receptor type, K | 0.0204382 |
| PTGS2 | prostaglandin-endoperoxide synthase 2 (prostaglandin G/H synthase and cyclooxygenase) | 0.0204309 |
| EXT1 | exostosin glycosyltransferase 1 | 0.0203637 |
| SMAD3 | SMAD family member 3 | 0.0202973 |
| XRN1 | 5'-3' exoribonuclease 1 | 0.0201707 |
| UTRN | utrophin | 0.0201025 |
| RPS12 | ribosomal protein S12 | 0.0196791 |
| GNGT1 | guanine nucleotide binding protein (G protein), gamma transducing activity polypeptide 1 | 0.0196784 |
| SPIDR | scaffolding protein involved in DNA repair | 0.0196767 |
| HDAC9 | histone deacetylase 9 | 0.0196281 |
| FOSB | FBJ murine osteosarcoma viral oncogene homolog B | 0.0195461 |
| AHR | aryl hydrocarbon receptor | 0.0189049 |
| Symbol | Name | Standardized Value |
|---|---|---|
| TMSB10 | thymosin beta 10 | -0.150883 |
| GAPDH | glyceraldehyde-3-phosphate dehydrogenase | -0.124278 |
| MT2A | metallothionein 2A | -0.0805534 |
| NDRG1 | N-myc downstream regulated 1 | -0.0801537 |
| PTMA | prothymosin, alpha | -0.078954 |
| LOX | lysyl oxidase | -0.0729476 |
| IGFBP3 | insulin-like growth factor binding protein 3 | -0.0677915 |
| WSB1 | WD repeat and SOCS box containing 1 | -0.0617771 |
| HIF1A | hypoxia inducible factor 1, alpha subunit (basic helix-loop-helix transcription factor) | -0.0592779 |
| NRP1 | neuropilin 1 | -0.0569823 |
| FN1 | fibronectin 1 | -0.0526162 |
| RBPJ | recombination signal binding protein for immunoglobulin kappa J region | -0.0511339 |
| PTPN12 | protein tyrosine phosphatase, non-receptor type 12 | -0.0505118 |
| STC1 | stanniocalcin 1 | -0.0504326 |
| HMGA2 | high mobility group AT-hook 2 | -0.0468255 |
| FTL | ferritin, light polypeptide | -0.0466443 |
| GLCCI1 | glucocorticoid induced 1 | -0.0464604 |
| PHLDA1 | pleckstrin homology-like domain, family A, member 1 | -0.0455533 |
| ITGA2 | integrin, alpha 2 (CD49B, alpha 2 subunit of VLA-2 receptor) | -0.0452347 |
| ERO1A | endoplasmic reticulum oxidoreductase 1 alpha | -0.0446468 |
| PABPC1 | poly(A) binding protein, cytoplasmic 1 | -0.0443126 |
| TIMP1 | TIMP metallopeptidase inhibitor 1 | -0.0441468 |
| MAP4K4 | mitogen-activated protein kinase kinase kinase kinase 4 | -0.0432688 |
| LMAN1 | lectin, mannose-binding, 1 | -0.0427633 |
| UBE2H | ubiquitin-conjugating enzyme E2H | -0.0414599 |
| ITGB1 | integrin, beta 1 (fibronectin receptor, beta polypeptide, antigen CD29 includes MDF2, MSK12) | -0.0405671 |
| HSP90B1 | heat shock protein 90kDa beta (Grp94), member 1 | -0.0384011 |
| EGR1 | early growth response 1 | -0.0381545 |
| ABCA1 | ATP-binding cassette, sub-family A (ABC1), member 1 | -0.036339 |
| WDR45B | WD repeat domain 45B | -0.0361707 |
| ZEB2 | zinc finger E-box binding homeobox 2 | -0.0350591 |
| ENO2 | enolase 2 (gamma, neuronal) | -0.0348973 |
| RAB27B | RAB27B, member RAS oncogene family | -0.0345856 |
| HMGA1 | high mobility group AT-hook 1 | -0.0343443 |
| P4HB | prolyl 4-hydroxylase, beta polypeptide | -0.0343214 |
| SERPINE1 | serpin peptidase inhibitor, clade E (nexin, plasminogen activator inhibitor type 1), member 1 | -0.0335024 |
| OXSR1 | oxidative stress responsive 1 | -0.0314852 |
| TGM2 | transglutaminase 2 | -0.0311672 |
| CD55 | CD55 molecule, decay accelerating factor for complement (Cromer blood group) | -0.0311283 |
| UBR5 | ubiquitin protein ligase E3 component n-recognin 5 | -0.0302227 |
| SPRED2 | sprouty-related, EVH1 domain containing 2 | -0.0294267 |
| B4GALT5 | UDP-Gal:betaGlcNAc beta 1,4- galactosyltransferase, polypeptide 5 | -0.0284255 |
| NUMB | numb homolog (Drosophila) | -0.0282253 |
| SMURF1 | SMAD specific E3 ubiquitin protein ligase 1 | -0.027945 |
| WAC | WW domain containing adaptor with coiled-coil | -0.0278134 |
| PLAUR | plasminogen activator, urokinase receptor | -0.0278031 |
| SS18 | synovial sarcoma translocation, chromosome 18 | -0.027572 |
| KPNB1 | karyopherin (importin) beta 1 | -0.027144 |
| CSGALNACT1 | chondroitin sulfate N-acetylgalactosaminyltransferase 1 | -0.027119 |
| PPFIBP1 | PTPRF interacting protein, binding protein 1 (liprin beta 1) | -0.0271031 |
| IFI6 | interferon, alpha-inducible protein 6 | -0.0270833 |
| TFPI2 | tissue factor pathway inhibitor 2 | -0.0269252 |
| RAB7A | RAB7A, member RAS oncogene family | -0.026795 |
| WASF2 | WAS protein family, member 2 | -0.0266036 |
| S100A6 | S100 calcium binding protein A6 | -0.0265688 |
| RAB6A | RAB6A, member RAS oncogene family | -0.0258821 |
| SPAG9 | sperm associated antigen 9 | -0.0257565 |
| GNB1 | guanine nucleotide binding protein (G protein), beta polypeptide 1 | -0.0257472 |
| CALR | calreticulin | -0.0252228 |
| HILPDA | hypoxia inducible lipid droplet-associated | -0.0251745 |
| ITCH | itchy E3 ubiquitin protein ligase | -0.024943 |
| RAP1B | RAP1B, member of RAS oncogene family | -0.0249031 |
| SOX4 | SRY (sex determining region Y)-box 4 | -0.0248181 |
| KTN1 | kinectin 1 (kinesin receptor) | -0.0248118 |
| RPS19 | ribosomal protein S19 | -0.0246379 |
| MTSS1 | metastasis suppressor 1 | -0.0245689 |
| GRB10 | growth factor receptor-bound protein 10 | -0.0245504 |
| FTH1 | ferritin, heavy polypeptide 1 | -0.0244034 |
| CA12 | carbonic anhydrase XII | -0.0241776 |
| PARP8 | poly (ADP-ribose) polymerase family, member 8 | -0.0241523 |
| HLA-B | major histocompatibility complex, class I, B | -0.0240556 |
| MYO1B | myosin IB | -0.0240105 |
| KMT2E | lysine (K)-specific methyltransferase 2E | -0.0238272 |
| MYO10 | myosin X | -0.0237832 |
| RAB1A | RAB1A, member RAS oncogene family | -0.0236962 |
| RICTOR | RPTOR independent companion of MTOR, complex 2 | -0.0236258 |
| H1-0 | H1.0 linker histone | -0.0234108 |
| MAP2K1 | mitogen-activated protein kinase kinase 1 | -0.0233576 |
| CTNND1 | catenin (cadherin-associated protein), delta 1 | -0.0231659 |
| TINAGL1 | tubulointerstitial nephritis antigen-like 1 | -0.0231474 |
| PGK1 | phosphoglycerate kinase 1 | -0.0230724 |
| RIOK3 | RIO kinase 3 | -0.0230582 |
| ITGB3 | integrin, beta 3 (platelet glycoprotein IIIa, antigen CD61) | -0.0224315 |
| NPEPPS | aminopeptidase puromycin sensitive | -0.0224146 |
| SNX9 | sorting nexin 9 | -0.02239 |
| DDX17 | DEAD (Asp-Glu-Ala-Asp) box helicase 17 | -0.0223841 |
| ARID4B | AT rich interactive domain 4B (RBP1-like) | -0.0223574 |
| BMPR2 | bone morphogenetic protein receptor, type II (serine/threonine kinase) | -0.0222331 |
| FOXO3 | forkhead box O3 | -0.022013 |
| SEMA3A | sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3A | -0.0215639 |
| SETD5 | SET domain containing 5 | -0.0214604 |
| PAFAH1B1 | platelet-activating factor acetylhydrolase 1b, regulatory subunit 1 (45kDa) | -0.0212675 |
| NR3C1 | nuclear receptor subfamily 3, group C, member 1 (glucocorticoid receptor) | -0.021252 |
| AFF4 | AF4/FMR2 family, member 4 | -0.0212285 |
| GPAT3 | glycerol-3-phosphate acyltransferase 3 | -0.021057 |
| B2M | beta-2-microglobulin | -0.0209877 |
| ARL4C | ADP-ribosylation factor-like 4C | -0.0205442 |
| CDCP1 | CUB domain containing protein 1 | -0.0204765 |
| RAI1 | retinoic acid induced 1 | -0.0204506 |
| POLD4 | polymerase (DNA-directed), delta 4, accessory subunit | -0.0201633 |
