| Dataset | Tahoe Therapeutics Tahoe 100M Perturbation Atlas |
| Category | transcriptomics |
| Type | cell type |
| Description | Erlotinib perturbation in NCI-H2030 cell line (Tahoe Therapeutics) |
| Similar Terms | |
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200 genes differentially expressed following the Erlotinib_NCI-H2030 drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| TXNRD1 | thioredoxin reductase 1 | 0.0974064 |
| AKAP12 | A kinase (PRKA) anchor protein 12 | 0.0845467 |
| GRAMD1B | GRAM domain containing 1B | 0.0821301 |
| POTEF | POTE ankyrin domain family, member F | 0.0793451 |
| HSP90AB1 | heat shock protein 90kDa alpha (cytosolic), class B member 1 | 0.0667044 |
| ROBO2 | roundabout, axon guidance receptor, homolog 2 (Drosophila) | 0.0646 |
| FTH1 | ferritin, heavy polypeptide 1 | 0.0603605 |
| ANKRD11 | ankyrin repeat domain 11 | 0.036599 |
| MTHFD2 | methylenetetrahydrofolate dehydrogenase (NADP+ dependent) 2, methenyltetrahydrofolate cyclohydrolase | 0.0315074 |
| APLP2 | amyloid beta (A4) precursor-like protein 2 | 0.0309299 |
| MSN | moesin | 0.0300924 |
| EEF2 | eukaryotic translation elongation factor 2 | 0.0297977 |
| BNIP3L | BCL2/adenovirus E1B 19kDa interacting protein 3-like | 0.0274929 |
| LOC102724023 | ES1 protein homolog, mitochondrial | 0.0261529 |
| MCFD2 | multiple coagulation factor deficiency 2 | 0.0256502 |
| EIF2S2 | eukaryotic translation initiation factor 2, subunit 2 beta, 38kDa | 0.0249243 |
| RPS2 | ribosomal protein S2 | 0.0240956 |
| RPS6 | ribosomal protein S6 | 0.0237389 |
| MYADM | myeloid-associated differentiation marker | 0.023523 |
| CENPF | centromere protein F, 350/400kDa | 0.0234894 |
| STC2 | stanniocalcin 2 | 0.0229973 |
| THSD4 | thrombospondin, type I, domain containing 4 | 0.0219739 |
| CITED2 | Cbp/p300-interacting transactivator, with Glu/Asp-rich carboxy-terminal domain, 2 | 0.0217143 |
| HNRNPDL | heterogeneous nuclear ribonucleoprotein D-like | 0.0213864 |
| HDGF | hepatoma-derived growth factor | 0.0210773 |
| DARS1 | aspartyl-tRNA synthetase 1 | 0.0210481 |
| TBC1D8 | TBC1 domain family, member 8 (with GRAM domain) | 0.020691 |
| VIM | vimentin | 0.0205588 |
| EEF1A1 | eukaryotic translation elongation factor 1 alpha 1 | 0.0204445 |
| PPP3CA | protein phosphatase 3, catalytic subunit, alpha isozyme | 0.0198302 |
| AXL | AXL receptor tyrosine kinase | 0.0197382 |
| TPM3 | tropomyosin 3 | 0.0192058 |
| MAP1B | microtubule-associated protein 1B | 0.0191842 |
| CBX3 | chromobox homolog 3 | 0.0191636 |
| RPL3 | ribosomal protein L3 | 0.0188573 |
| IER2 | immediate early response 2 | 0.0186244 |
| EDIL3 | EGF-like repeats and discoidin I-like domains 3 | 0.018089 |
| EIF3A | eukaryotic translation initiation factor 3, subunit A | 0.0180731 |
| ATF4 | activating transcription factor 4 | 0.017658 |
| TBC1D5 | TBC1 domain family, member 5 | 0.0173889 |
| TIMP1 | TIMP metallopeptidase inhibitor 1 | 0.0173298 |
| TMBIM6 | transmembrane BAX inhibitor motif containing 6 | 0.0171581 |
| CSDE1 | cold shock domain containing E1, RNA-binding | 0.0170552 |
| IL6 | interleukin 6 | 0.0170162 |
| RACK1 | receptor for activated C kinase 1 | 0.0161931 |
| MIER1 | mesoderm induction early response 1, transcriptional regulator | 0.0160668 |
| CTNNA1 | catenin (cadherin-associated protein), alpha 1, 102kDa | 0.015854 |
| ITGA6 | integrin, alpha 6 | 0.0156246 |
| CDC42BPA | CDC42 binding protein kinase alpha (DMPK-like) | 0.0153772 |
| BABAM2 | BRISC and BRCA1 A complex member 2 | 0.015219 |
| SLC7A11 | solute carrier family 7 (anionic amino acid transporter light chain, xc- system), member 11 | 0.0150945 |
| RNF145 | ring finger protein 145 | 0.0150743 |
| PDLIM5 | PDZ and LIM domain 5 | 0.0149852 |
| SRGN | serglycin | 0.0149021 |
| TCEA1 | transcription elongation factor A (SII), 1 | 0.0147136 |
| ANKRD12 | ankyrin repeat domain 12 | 0.0147034 |
| FOXP1 | forkhead box P1 | 0.0146974 |
| YWHAG | tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, gamma | 0.014692 |
| UACA | uveal autoantigen with coiled-coil domains and ankyrin repeats | 0.0145907 |
| UBXN4 | UBX domain protein 4 | 0.0144909 |
| NCEH1 | neutral cholesterol ester hydrolase 1 | 0.014476 |
| ANP32B | acidic (leucine-rich) nuclear phosphoprotein 32 family, member B | 0.0143376 |
| DSTN | destrin (actin depolymerizing factor) | 0.014002 |
| STK24 | serine/threonine kinase 24 | 0.0139356 |
| YWHAH | tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, eta | 0.0134623 |
| CDCP1 | CUB domain containing protein 1 | 0.0133691 |
| LRRFIP1 | leucine rich repeat (in FLII) interacting protein 1 | 0.0133579 |
| MARCHF4 | membrane associated ring-CH-type finger 4 | 0.0131201 |
| ATL3 | atlastin GTPase 3 | 0.0130182 |
| SRSF5 | serine/arginine-rich splicing factor 5 | 0.0128441 |
| SUPT16H | suppressor of Ty 16 homolog (S. cerevisiae) | 0.0127971 |
| SLK | STE20-like kinase | 0.0127733 |
| COX16 | COX16 cytochrome c oxidase assembly homolog (S. cerevisiae) | 0.0125127 |
| AUP1 | ancient ubiquitous protein 1 | 0.0124829 |
| EEF1G | eukaryotic translation elongation factor 1 gamma | 0.0124825 |
| ATP5F1A | ATP synthase F1 subunit alpha | 0.0123525 |
| FBXL5 | F-box and leucine-rich repeat protein 5 | 0.0122862 |
| PCED1B | PC-esterase domain containing 1B | 0.0121585 |
| HLA-A | major histocompatibility complex, class I, A | 0.0119976 |
| BNIP3 | BCL2/adenovirus E1B 19kDa interacting protein 3 | 0.0119554 |
| ATRX | alpha thalassemia/mental retardation syndrome X-linked | 0.011945 |
| ATP11A | ATPase, class VI, type 11A | 0.0119259 |
| IGF2BP2 | insulin-like growth factor 2 mRNA binding protein 2 | 0.0118486 |
| PNN | pinin, desmosome associated protein | 0.0117769 |
| INHBA | inhibin, beta A | 0.0117107 |
| SET | SET nuclear proto-oncogene | 0.0116436 |
| ZNF638 | zinc finger protein 638 | 0.0116417 |
| HDGFL3 | HDGF like 3 | 0.0115931 |
| CXCL8 | chemokine (C-X-C motif) ligand 8 | 0.0115605 |
| SMC4 | structural maintenance of chromosomes 4 | 0.0115049 |
| KIFC3 | kinesin family member C3 | 0.0114108 |
| EPRS1 | glutamyl-prolyl-tRNA synthetase 1 | 0.0113405 |
| IRF2BPL | interferon regulatory factor 2 binding protein-like | 0.0112462 |
| SMC1A | structural maintenance of chromosomes 1A | 0.0112064 |
| VMP1 | vacuole membrane protein 1 | 0.0111397 |
| EGLN1 | egl-9 family hypoxia-inducible factor 1 | 0.0109846 |
| PRKN | parkin RBR E3 ubiquitin protein ligase | 0.0109183 |
| KTN1 | kinectin 1 (kinesin receptor) | 0.010881 |
| RAD51B | RAD51 paralog B | 0.0107555 |
| RPS27 | ribosomal protein S27 | 0.0107499 |
| Symbol | Name | Standardized Value |
|---|---|---|
| GAPDH | glyceraldehyde-3-phosphate dehydrogenase | -0.225644 |
| HSPA5 | heat shock 70kDa protein 5 (glucose-regulated protein, 78kDa) | -0.223517 |
| PM20D1 | peptidase M20 domain containing 1 | -0.184538 |
| FTL | ferritin, light polypeptide | -0.165053 |
| ERO1A | endoplasmic reticulum oxidoreductase 1 alpha | -0.160918 |
| MT2A | metallothionein 2A | -0.151969 |
| TM4SF1 | transmembrane 4 L six family member 1 | -0.137128 |
| PTMA | prothymosin, alpha | -0.0899023 |
| HSP90B1 | heat shock protein 90kDa beta (Grp94), member 1 | -0.0897469 |
| RPL23 | ribosomal protein L23 | -0.0715178 |
| PARD3 | par-3 family cell polarity regulator | -0.0684636 |
| AHNAK | AHNAK nucleoprotein | -0.0658778 |
| RBM39 | RNA binding motif protein 39 | -0.0639184 |
| RPL19 | ribosomal protein L19 | -0.0629672 |
| TMSB10 | thymosin beta 10 | -0.0620434 |
| TPT1 | tumor protein, translationally-controlled 1 | -0.0615668 |
| IER3 | immediate early response 3 | -0.0603241 |
| APP | amyloid beta (A4) precursor protein | -0.059613 |
| RAB1A | RAB1A, member RAS oncogene family | -0.0571477 |
| S100A10 | S100 calcium binding protein A10 | -0.057088 |
| RPS4Y1 | ribosomal protein S4, Y-linked 1 | -0.0561835 |
| ACTG1 | actin gamma 1 | -0.0527525 |
| ANXA2 | annexin A2 | -0.0523325 |
| FGB | fibrinogen beta chain | -0.049933 |
| C15ORF48 | chromosome 15 open reading frame 48 | -0.0495956 |
| EIF3H | eukaryotic translation initiation factor 3, subunit H | -0.0495732 |
| MKLN1 | muskelin 1, intracellular mediator containing kelch motifs | -0.049381 |
| AP2B1 | adaptor-related protein complex 2, beta 1 subunit | -0.0491739 |
| SAMD4A | sterile alpha motif domain containing 4A | -0.047771 |
| FUS | FUS RNA binding protein | -0.0473325 |
| KDM3A | lysine (K)-specific demethylase 3A | -0.0461923 |
| DSCAM | Down syndrome cell adhesion molecule | -0.0450332 |
| ELL2 | elongation factor, RNA polymerase II, 2 | -0.0448276 |
| STAU1 | staufen double-stranded RNA binding protein 1 | -0.042323 |
| CALR | calreticulin | -0.0417478 |
| HNRNPH1 | heterogeneous nuclear ribonucleoprotein H1 (H) | -0.0403546 |
| BASP1 | brain abundant, membrane attached signal protein 1 | -0.0403273 |
| RERE | arginine-glutamic acid dipeptide (RE) repeats | -0.0400606 |
| POLR2A | polymerase (RNA) II (DNA directed) polypeptide A, 220kDa | -0.0400603 |
| STAT3 | signal transducer and activator of transcription 3 (acute-phase response factor) | -0.0400475 |
| CFLAR | CASP8 and FADD-like apoptosis regulator | -0.0397736 |
| GNAS | GNAS complex locus | -0.0392269 |
| CRIM1 | cysteine rich transmembrane BMP regulator 1 (chordin-like) | -0.039178 |
| ZFAND3 | zinc finger, AN1-type domain 3 | -0.0385462 |
| KHDC4 | KH domain containing 4, pre-mRNA splicing factor | -0.0379101 |
| FMNL2 | formin-like 2 | -0.0378235 |
| NEDD4L | neural precursor cell expressed, developmentally down-regulated 4-like, E3 ubiquitin protein ligase | -0.0375858 |
| DENND4A | DENN/MADD domain containing 4A | -0.0370613 |
| PLOD2 | procollagen-lysine, 2-oxoglutarate 5-dioxygenase 2 | -0.036892 |
| IGF2 | insulin-like growth factor 2 | -0.036345 |
| ASPH | aspartate beta-hydroxylase | -0.0362713 |
| NOP58 | NOP58 ribonucleoprotein | -0.0361788 |
| TFPI | tissue factor pathway inhibitor (lipoprotein-associated coagulation inhibitor) | -0.0358207 |
| TFPI2 | tissue factor pathway inhibitor 2 | -0.0355439 |
| CAVIN1 | caveolae associated protein 1 | -0.0353593 |
| RHEB | Ras homolog enriched in brain | -0.0346791 |
| ITGB1 | integrin, beta 1 (fibronectin receptor, beta polypeptide, antigen CD29 includes MDF2, MSK12) | -0.0345535 |
| USP3 | ubiquitin specific peptidase 3 | -0.033554 |
| YWHAE | tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, epsilon | -0.0335114 |
| RAD21 | RAD21 homolog (S. pombe) | -0.0334793 |
| EIF4A2 | eukaryotic translation initiation factor 4A2 | -0.0334077 |
| MARCHF6 | membrane associated ring-CH-type finger 6 | -0.0332937 |
| STC1 | stanniocalcin 1 | -0.0331869 |
| RPS24 | ribosomal protein S24 | -0.0331064 |
| HNRNPA2B1 | heterogeneous nuclear ribonucleoprotein A2/B1 | -0.0325468 |
| TRIO | trio Rho guanine nucleotide exchange factor | -0.0321472 |
| KYNU | kynureninase | -0.0321405 |
| PKM | pyruvate kinase, muscle | -0.0319794 |
| FNDC3B | fibronectin type III domain containing 3B | -0.0317493 |
| SF3B2 | splicing factor 3b, subunit 2, 145kDa | -0.0315438 |
| GNB1 | guanine nucleotide binding protein (G protein), beta polypeptide 1 | -0.0314054 |
| UBR5 | ubiquitin protein ligase E3 component n-recognin 5 | -0.0308893 |
| NAMPT | nicotinamide phosphoribosyltransferase | -0.0308854 |
| ARIH1 | ariadne RBR E3 ubiquitin protein ligase 1 | -0.030758 |
| RPL35A | ribosomal protein L35a | -0.0303069 |
| PUM2 | pumilio RNA-binding family member 2 | -0.0302012 |
| DYNC1H1 | dynein, cytoplasmic 1, heavy chain 1 | -0.0292266 |
| CFDP1 | craniofacial development protein 1 | -0.0290435 |
| SPTBN1 | spectrin, beta, non-erythrocytic 1 | -0.0289789 |
| ARL6IP1 | ADP-ribosylation factor-like 6 interacting protein 1 | -0.028895 |
| NEGR1 | neuronal growth regulator 1 | -0.0288432 |
| HMGB1 | high mobility group box 1 | -0.0288117 |
| AHR | aryl hydrocarbon receptor | -0.0284797 |
| YBX1 | Y box binding protein 1 | -0.0284249 |
| SIPA1L1 | signal-induced proliferation-associated 1 like 1 | -0.0283652 |
| ANLN | anillin, actin binding protein | -0.0283555 |
| CNOT1 | CCR4-NOT transcription complex, subunit 1 | -0.0282413 |
| PABPC1 | poly(A) binding protein, cytoplasmic 1 | -0.0282274 |
| RPL34 | ribosomal protein L34 | -0.0280463 |
| SOD2 | superoxide dismutase 2, mitochondrial | -0.0279019 |
| NCOR1 | nuclear receptor corepressor 1 | -0.0278981 |
| RPS15 | ribosomal protein S15 | -0.0277587 |
| CDK12 | cyclin-dependent kinase 12 | -0.0277078 |
| MACF1 | microtubule-actin crosslinking factor 1 | -0.0276074 |
| LANCL1 | LanC lantibiotic synthetase component C-like 1 (bacterial) | -0.0275694 |
| ARPC2 | actin related protein 2/3 complex, subunit 2, 34kDa | -0.0275364 |
| ABL2 | ABL proto-oncogene 2, non-receptor tyrosine kinase | -0.027348 |
| VDAC1 | voltage-dependent anion channel 1 | -0.0273222 |
| BTBD7 | BTB (POZ) domain containing 7 | -0.0272887 |
| MYL12B | myosin, light chain 12B, regulatory | -0.0272705 |
