| Dataset | Tahoe Therapeutics Tahoe 100M Perturbation Atlas |
| Category | transcriptomics |
| Type | cell type |
| Description | Erlotinib perturbation in NCI-H2122 cell line (Tahoe Therapeutics) |
| Similar Terms | |
| Downloads & Tools |
200 genes differentially expressed following the Erlotinib_NCI-H2122 drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| RPS6 | ribosomal protein S6 | 0.0891408 |
| HSP90B1 | heat shock protein 90kDa beta (Grp94), member 1 | 0.0862492 |
| VIM | vimentin | 0.0751232 |
| HSP90AB1 | heat shock protein 90kDa alpha (cytosolic), class B member 1 | 0.0733048 |
| KTN1 | kinectin 1 (kinesin receptor) | 0.0691367 |
| ZNF292 | zinc finger protein 292 | 0.0646371 |
| GARS1 | glycyl-tRNA synthetase 1 | 0.0587736 |
| RPS8 | ribosomal protein S8 | 0.0560303 |
| CANX | calnexin | 0.0554104 |
| PTMA | prothymosin, alpha | 0.0523129 |
| CD55 | CD55 molecule, decay accelerating factor for complement (Cromer blood group) | 0.0522968 |
| SUCO | SUN domain containing ossification factor | 0.0503809 |
| RTN4 | reticulon 4 | 0.0502774 |
| CXCL8 | chemokine (C-X-C motif) ligand 8 | 0.0500199 |
| RBPJ | recombination signal binding protein for immunoglobulin kappa J region | 0.0493855 |
| RPL26 | ribosomal protein L26 | 0.0487754 |
| EEF2 | eukaryotic translation elongation factor 2 | 0.0481318 |
| WAC | WW domain containing adaptor with coiled-coil | 0.0467916 |
| HDAC9 | histone deacetylase 9 | 0.0448016 |
| TTC3 | tetratricopeptide repeat domain 3 | 0.0441588 |
| EIF1 | eukaryotic translation initiation factor 1 | 0.0437205 |
| RB1CC1 | RB1-inducible coiled-coil 1 | 0.0435057 |
| ENO1 | enolase 1, (alpha) | 0.0430167 |
| RPLP0 | ribosomal protein, large, P0 | 0.0426093 |
| LDHA | lactate dehydrogenase A | 0.0415751 |
| PTBP3 | polypyrimidine tract binding protein 3 | 0.0409589 |
| DTNA | dystrobrevin, alpha | 0.040919 |
| PRRC2C | proline-rich coiled-coil 2C | 0.0390873 |
| PABPC1 | poly(A) binding protein, cytoplasmic 1 | 0.0387162 |
| UBR5 | ubiquitin protein ligase E3 component n-recognin 5 | 0.0384135 |
| RNF145 | ring finger protein 145 | 0.0382474 |
| AKT3 | v-akt murine thymoma viral oncogene homolog 3 | 0.0381565 |
| DSTN | destrin (actin depolymerizing factor) | 0.0372546 |
| TPM4 | tropomyosin 4 | 0.0368885 |
| PSME4 | proteasome (prosome, macropain) activator subunit 4 | 0.03679 |
| FOXJ3 | forkhead box J3 | 0.0365978 |
| SPAG9 | sperm associated antigen 9 | 0.0364395 |
| BZW1 | basic leucine zipper and W2 domains 1 | 0.036428 |
| TFG | TRK-fused gene | 0.0362059 |
| UBA6 | ubiquitin-like modifier activating enzyme 6 | 0.0354152 |
| FAM13A | family with sequence similarity 13, member A | 0.0346082 |
| NAMPT | nicotinamide phosphoribosyltransferase | 0.0345517 |
| PSMA6 | proteasome (prosome, macropain) subunit, alpha type, 6 | 0.0341084 |
| PPP1R12A | protein phosphatase 1, regulatory subunit 12A | 0.0338809 |
| HSPD1 | heat shock 60kDa protein 1 (chaperonin) | 0.0337866 |
| RHOBTB3 | Rho-related BTB domain containing 3 | 0.0336549 |
| STC1 | stanniocalcin 1 | 0.0336293 |
| NDRG1 | N-myc downstream regulated 1 | 0.0335914 |
| EHBP1 | EH domain binding protein 1 | 0.0334816 |
| RPL35 | ribosomal protein L35 | 0.0332343 |
| PPFIBP1 | PTPRF interacting protein, binding protein 1 (liprin beta 1) | 0.0332008 |
| P4HA1 | prolyl 4-hydroxylase, alpha polypeptide I | 0.0331693 |
| HNRNPK | heterogeneous nuclear ribonucleoprotein K | 0.032852 |
| RBM39 | RNA binding motif protein 39 | 0.0328512 |
| RYBP | RING1 and YY1 binding protein | 0.0326587 |
| ATP13A3 | ATPase type 13A3 | 0.0324857 |
| ERC2 | ELKS/RAB6-interacting/CAST family member 2 | 0.032324 |
| CSDE1 | cold shock domain containing E1, RNA-binding | 0.0318989 |
| ENAH | enabled homolog (Drosophila) | 0.0309887 |
| PHIP | pleckstrin homology domain interacting protein | 0.0309792 |
| GPHN | gephyrin | 0.0309126 |
| RUNX1 | runt-related transcription factor 1 | 0.0304811 |
| ERRFI1 | ERBB receptor feedback inhibitor 1 | 0.0304759 |
| ERO1A | endoplasmic reticulum oxidoreductase 1 alpha | 0.0304064 |
| H3-3B | H3.3 histone B | 0.0302121 |
| ASPH | aspartate beta-hydroxylase | 0.0301223 |
| LAMB1 | laminin, beta 1 | 0.029877 |
| MEMO1 | mediator of cell motility 1 | 0.0297608 |
| SERPINE1 | serpin peptidase inhibitor, clade E (nexin, plasminogen activator inhibitor type 1), member 1 | 0.0296378 |
| PPP2R5E | protein phosphatase 2, regulatory subunit B', epsilon isoform | 0.0295414 |
| CAVIN1 | caveolae associated protein 1 | 0.0295257 |
| GNPDA1 | glucosamine-6-phosphate deaminase 1 | 0.0294365 |
| MDM2 | MDM2 proto-oncogene, E3 ubiquitin protein ligase | 0.0293127 |
| EPB41L2 | erythrocyte membrane protein band 4.1-like 2 | 0.0291223 |
| CDC73 | cell division cycle 73 | 0.0288439 |
| NFAT5 | nuclear factor of activated T-cells 5, tonicity-responsive | 0.0287053 |
| GOLT1B | golgi transport 1B | 0.0285593 |
| HNRNPU | heterogeneous nuclear ribonucleoprotein U (scaffold attachment factor A) | 0.0285197 |
| PAN3 | PAN3 poly(A) specific ribonuclease subunit | 0.0283214 |
| RPS27 | ribosomal protein S27 | 0.0281131 |
| YWHAE | tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, epsilon | 0.0278804 |
| MAGI2 | membrane associated guanylate kinase, WW and PDZ domain containing 2 | 0.0276407 |
| BHLHE40 | basic helix-loop-helix family, member e40 | 0.0274487 |
| SEMA3A | sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3A | 0.027429 |
| MARCHF7 | membrane associated ring-CH-type finger 7 | 0.0272131 |
| DST | dystonin | 0.0270153 |
| PNISR | PNN-interacting serine/arginine-rich protein | 0.0270025 |
| MXI1 | MAX interactor 1, dimerization protein | 0.026907 |
| DYRK1A | dual-specificity tyrosine-(Y)-phosphorylation regulated kinase 1A | 0.0268691 |
| FAM133B | family with sequence similarity 133, member B | 0.0268104 |
| MMAB | methylmalonic aciduria (cobalamin deficiency) cblB type | 0.0267968 |
| TPR | translocated promoter region, nuclear basket protein | 0.0264435 |
| RLF | rearranged L-myc fusion | 0.0259605 |
| USP3 | ubiquitin specific peptidase 3 | 0.0256636 |
| CNOT4 | CCR4-NOT transcription complex, subunit 4 | 0.0256256 |
| PRKCI | protein kinase C, iota | 0.0252419 |
| HNRNPA1 | heterogeneous nuclear ribonucleoprotein A1 | 0.0251134 |
| RPL35A | ribosomal protein L35a | 0.0250633 |
| SLMAP | sarcolemma associated protein | 0.0248746 |
| TOP1 | topoisomerase (DNA) I | 0.0248561 |
| Symbol | Name | Standardized Value |
|---|---|---|
| IGF2 | insulin-like growth factor 2 | -0.121217 |
| MT2A | metallothionein 2A | -0.102013 |
| FBF1 | Fas (TNFRSF6) binding factor 1 | -0.067272 |
| SERPINA1 | serpin peptidase inhibitor, clade A (alpha-1 antiproteinase, antitrypsin), member 1 | -0.0638158 |
| FTL | ferritin, light polypeptide | -0.0627684 |
| MACF1 | microtubule-actin crosslinking factor 1 | -0.0595013 |
| AKAP12 | A kinase (PRKA) anchor protein 12 | -0.0570863 |
| ANXA2 | annexin A2 | -0.0532693 |
| RNF213 | ring finger protein 213 | -0.0529483 |
| PDE10A | phosphodiesterase 10A | -0.0515245 |
| KANSL1 | KAT8 regulatory NSL complex subunit 1 | -0.0473243 |
| GPC6 | glypican 6 | -0.04639 |
| SVIL | supervillin | -0.0462738 |
| NALF1 | NALCN channel auxiliary factor 1 | -0.0453358 |
| SIPA1L3 | signal-induced proliferation-associated 1 like 3 | -0.0438745 |
| ITGA2 | integrin, alpha 2 (CD49B, alpha 2 subunit of VLA-2 receptor) | -0.0433225 |
| SMYD3 | SET and MYND domain containing 3 | -0.0413516 |
| MYO1E | myosin IE | -0.0398793 |
| SASH1 | SAM and SH3 domain containing 1 | -0.0392229 |
| ERBIN | erbb2 interacting protein | -0.0388277 |
| KYNU | kynureninase | -0.0385702 |
| RAB10 | RAB10, member RAS oncogene family | -0.0378864 |
| KMT2C | lysine (K)-specific methyltransferase 2C | -0.0377275 |
| PATJ | PATJ crumbs cell polarity complex component | -0.0365518 |
| BRIP1 | BRCA1 interacting protein C-terminal helicase 1 | -0.0364516 |
| LMO7 | LIM domain 7 | -0.036405 |
| ARHGAP26 | Rho GTPase activating protein 26 | -0.0360542 |
| SMAD3 | SMAD family member 3 | -0.0356621 |
| PTPRM | protein tyrosine phosphatase, receptor type, M | -0.0353117 |
| EFNA5 | ephrin-A5 | -0.0335567 |
| SEMA5A | sema domain, seven thrombospondin repeats (type 1 and type 1-like), transmembrane domain (TM) and short cytoplasmic domain, (semaphorin) 5A | -0.0335049 |
| TAOK3 | TAO kinase 3 | -0.0334374 |
| NPC1 | Niemann-Pick disease, type C1 | -0.0334254 |
| TAS2R14 | taste receptor, type 2, member 14 | -0.0334083 |
| KIF13A | kinesin family member 13A | -0.0333896 |
| SUPT3H | suppressor of Ty 3 homolog (S. cerevisiae) | -0.0333102 |
| PAPPA | pregnancy-associated plasma protein A, pappalysin 1 | -0.0330701 |
| PARP14 | poly (ADP-ribose) polymerase family, member 14 | -0.032975 |
| SLC39A11 | solute carrier family 39, member 11 | -0.0325131 |
| STK4 | serine/threonine kinase 4 | -0.0320975 |
| NRG1 | neuregulin 1 | -0.0317596 |
| PDIA3 | protein disulfide isomerase family A, member 3 | -0.0316097 |
| SMCHD1 | structural maintenance of chromosomes flexible hinge domain containing 1 | -0.030965 |
| CPE | carboxypeptidase E | -0.0309343 |
| BBX | bobby sox homolog (Drosophila) | -0.0305841 |
| PHLDB2 | pleckstrin homology-like domain, family B, member 2 | -0.0304257 |
| RICTOR | RPTOR independent companion of MTOR, complex 2 | -0.0302597 |
| AKAP13 | A kinase (PRKA) anchor protein 13 | -0.0302177 |
| RPS16 | ribosomal protein S16 | -0.0301857 |
| MAP3K13 | mitogen-activated protein kinase kinase kinase 13 | -0.0299391 |
| ZBTB20 | zinc finger and BTB domain containing 20 | -0.0295729 |
| ANKRD17 | ankyrin repeat domain 17 | -0.0289795 |
| MMP12 | matrix metallopeptidase 12 | -0.0288228 |
| SOD2 | superoxide dismutase 2, mitochondrial | -0.0285059 |
| RBM15 | RNA binding motif protein 15 | -0.0282791 |
| GSK3B | glycogen synthase kinase 3 beta | -0.0278671 |
| CALM1 | calmodulin 1 (phosphorylase kinase, delta) | -0.0278284 |
| PRKCA | protein kinase C, alpha | -0.0276599 |
| RERE | arginine-glutamic acid dipeptide (RE) repeats | -0.0276359 |
| MAP7 | microtubule-associated protein 7 | -0.0276153 |
| NCOA3 | nuclear receptor coactivator 3 | -0.0275359 |
| LPP | LIM domain containing preferred translocation partner in lipoma | -0.0275325 |
| C3 | complement component 3 | -0.0274816 |
| KIAA1217 | KIAA1217 | -0.0273883 |
| ZC3HAV1 | zinc finger CCCH-type, antiviral 1 | -0.0272818 |
| CDK17 | cyclin-dependent kinase 17 | -0.0268428 |
| TPD52 | tumor protein D52 | -0.0268182 |
| N4BP2L2 | NEDD4 binding protein 2-like 2 | -0.0267446 |
| SEPTIN11 | septin 11 | -0.026726 |
| ALCAM | activated leukocyte cell adhesion molecule | -0.0265225 |
| STK24 | serine/threonine kinase 24 | -0.0262748 |
| RPL38 | ribosomal protein L38 | -0.0261554 |
| ZNF609 | zinc finger protein 609 | -0.026085 |
| SPTBN1 | spectrin, beta, non-erythrocytic 1 | -0.0257633 |
| HNRNPH1 | heterogeneous nuclear ribonucleoprotein H1 (H) | -0.0256066 |
| RBMS1 | RNA binding motif, single stranded interacting protein 1 | -0.0256042 |
| LOXL2 | lysyl oxidase-like 2 | -0.0254137 |
| IGF2BP2 | insulin-like growth factor 2 mRNA binding protein 2 | -0.0253883 |
| ECE1 | endothelin converting enzyme 1 | -0.0250517 |
| UGCG | UDP-glucose ceramide glucosyltransferase | -0.0248266 |
| BPTF | bromodomain PHD finger transcription factor | -0.0247536 |
| MBD5 | methyl-CpG binding domain protein 5 | -0.02472 |
| RNF19A | ring finger protein 19A, RBR E3 ubiquitin protein ligase | -0.0245397 |
| UBR4 | ubiquitin protein ligase E3 component n-recognin 4 | -0.024374 |
| JMJD1C | jumonji domain containing 1C | -0.024311 |
| PDXDC1 | pyridoxal-dependent decarboxylase domain containing 1 | -0.0241698 |
| LRCH3 | leucine-rich repeats and calponin homology (CH) domain containing 3 | -0.0240756 |
| EGFR | epidermal growth factor receptor | -0.0239299 |
| CTNNB1 | catenin (cadherin-associated protein), beta 1, 88kDa | -0.0237465 |
| SDC4 | syndecan 4 | -0.0237416 |
| UBE2E2 | ubiquitin-conjugating enzyme E2E 2 | -0.0236389 |
| BIRC6 | baculoviral IAP repeat containing 6 | -0.0235111 |
| INTS6 | integrator complex subunit 6 | -0.0233125 |
| DSPP | dentin sialophosphoprotein | -0.0231681 |
| ATOSA | atos homolog A | -0.0230968 |
| YWHAB | tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, beta | -0.0230966 |
| FBXO11 | F-box protein 11 | -0.0230779 |
| FOXO3 | forkhead box O3 | -0.0229452 |
| SLC25A37 | solute carrier family 25 (mitochondrial iron transporter), member 37 | -0.0228099 |
| KHDC4 | KH domain containing 4, pre-mRNA splicing factor | -0.0227134 |
