| Dataset | Tahoe Therapeutics Tahoe 100M Perturbation Atlas |
| Category | transcriptomics |
| Type | cell type |
| Description | Erlotinib perturbation in NCI-H2347 cell line (Tahoe Therapeutics) |
| Similar Terms | |
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200 genes differentially expressed following the Erlotinib_NCI-H2347 drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| HSP90AB1 | heat shock protein 90kDa alpha (cytosolic), class B member 1 | 0.156352 |
| POTEF | POTE ankyrin domain family, member F | 0.12969 |
| APLP2 | amyloid beta (A4) precursor-like protein 2 | 0.115383 |
| TOP2A | topoisomerase (DNA) II alpha 170kDa | 0.111841 |
| RACK1 | receptor for activated C kinase 1 | 0.0969945 |
| GOLGA4 | golgin A4 | 0.0729725 |
| CCNL1 | cyclin L1 | 0.0666132 |
| RPS12 | ribosomal protein S12 | 0.0631299 |
| RPLP0 | ribosomal protein, large, P0 | 0.05697 |
| NPM1 | nucleophosmin (nucleolar phosphoprotein B23, numatrin) | 0.0559841 |
| CALM2 | calmodulin 2 (phosphorylase kinase, delta) | 0.0558366 |
| MBOAT2 | membrane bound O-acyltransferase domain containing 2 | 0.0537642 |
| ARRDC3 | arrestin domain containing 3 | 0.0526973 |
| FAM13A | family with sequence similarity 13, member A | 0.0524371 |
| TMBIM6 | transmembrane BAX inhibitor motif containing 6 | 0.0519039 |
| FNDC3B | fibronectin type III domain containing 3B | 0.0508306 |
| CD47 | CD47 molecule | 0.0501458 |
| GPRC5A | G protein-coupled receptor, class C, group 5, member A | 0.0484061 |
| MAL2 | mal, T-cell differentiation protein 2 (gene/pseudogene) | 0.0474737 |
| RPL9 | ribosomal protein L9 | 0.0474438 |
| FHIP1A | FHF complex subunit HOOK interacting protein 1A | 0.047349 |
| RPS6 | ribosomal protein S6 | 0.0469811 |
| RPL30 | ribosomal protein L30 | 0.0469486 |
| DSTN | destrin (actin depolymerizing factor) | 0.0464284 |
| TOP1 | topoisomerase (DNA) I | 0.0463875 |
| PCBP2 | poly(rC) binding protein 2 | 0.0461252 |
| RPS23 | ribosomal protein S23 | 0.0448014 |
| ANXA5 | annexin A5 | 0.0443015 |
| BZW1 | basic leucine zipper and W2 domains 1 | 0.0439925 |
| RPL12 | ribosomal protein L12 | 0.043872 |
| BNIP3L | BCL2/adenovirus E1B 19kDa interacting protein 3-like | 0.0436143 |
| MSN | moesin | 0.0431772 |
| HSP90AA1 | heat shock protein 90kDa alpha (cytosolic), class A member 1 | 0.0431301 |
| LDHB | lactate dehydrogenase B | 0.0424332 |
| ECT2 | epithelial cell transforming 2 | 0.0414537 |
| CKAP5 | cytoskeleton associated protein 5 | 0.0399459 |
| HNRNPDL | heterogeneous nuclear ribonucleoprotein D-like | 0.0397218 |
| SLC2A3 | solute carrier family 2 (facilitated glucose transporter), member 3 | 0.0390687 |
| EZR | ezrin | 0.0389835 |
| VEGFA | vascular endothelial growth factor A | 0.0387825 |
| RPS2 | ribosomal protein S2 | 0.0381368 |
| RPS17 | ribosomal protein S17 | 0.0377712 |
| EIF3E | eukaryotic translation initiation factor 3, subunit E | 0.037459 |
| TFG | TRK-fused gene | 0.0369186 |
| RNF145 | ring finger protein 145 | 0.0367281 |
| RPS8 | ribosomal protein S8 | 0.0366601 |
| NACA | nascent polypeptide-associated complex alpha subunit | 0.0359984 |
| GARS1 | glycyl-tRNA synthetase 1 | 0.0355099 |
| RPL11 | ribosomal protein L11 | 0.0350804 |
| UBA6 | ubiquitin-like modifier activating enzyme 6 | 0.0350681 |
| RBM25 | RNA binding motif protein 25 | 0.0350674 |
| CBX3 | chromobox homolog 3 | 0.03504 |
| NAMPT | nicotinamide phosphoribosyltransferase | 0.0347233 |
| SLMAP | sarcolemma associated protein | 0.0342699 |
| TPM3 | tropomyosin 3 | 0.0342371 |
| ANXA1 | annexin A1 | 0.0339521 |
| FTH1 | ferritin, heavy polypeptide 1 | 0.0335236 |
| CXCL8 | chemokine (C-X-C motif) ligand 8 | 0.0334467 |
| ADAM9 | ADAM metallopeptidase domain 9 | 0.032689 |
| ITGB1 | integrin, beta 1 (fibronectin receptor, beta polypeptide, antigen CD29 includes MDF2, MSK12) | 0.0322471 |
| BHLHE40 | basic helix-loop-helix family, member e40 | 0.0319137 |
| TM9SF3 | transmembrane 9 superfamily member 3 | 0.0318594 |
| TXNRD1 | thioredoxin reductase 1 | 0.0315896 |
| PRRC2C | proline-rich coiled-coil 2C | 0.0315763 |
| ZFP36L1 | ZFP36 ring finger protein-like 1 | 0.0311488 |
| MSMO1 | methylsterol monooxygenase 1 | 0.0310972 |
| CTNNA1 | catenin (cadherin-associated protein), alpha 1, 102kDa | 0.0307848 |
| CLINT1 | clathrin interactor 1 | 0.0306348 |
| GPBP1 | GC-rich promoter binding protein 1 | 0.0298688 |
| RPL37A | ribosomal protein L37a | 0.0296902 |
| SEPTIN7 | septin 7 | 0.0296038 |
| BIRC3 | baculoviral IAP repeat containing 3 | 0.0294449 |
| RPL17-C18ORF32 | RPL17-C18orf32 readthrough | 0.0294172 |
| CENPF | centromere protein F, 350/400kDa | 0.0291692 |
| EIF4G2 | eukaryotic translation initiation factor 4 gamma, 2 | 0.0291623 |
| PEG10 | paternally expressed 10 | 0.0290119 |
| EEF2 | eukaryotic translation elongation factor 2 | 0.0290098 |
| KTN1 | kinectin 1 (kinesin receptor) | 0.0287837 |
| RPL7 | ribosomal protein L7 | 0.0286393 |
| AREG | amphiregulin | 0.028541 |
| SREK1 | splicing regulatory glutamine/lysine-rich protein 1 | 0.028297 |
| PDIA3 | protein disulfide isomerase family A, member 3 | 0.0275236 |
| SMC4 | structural maintenance of chromosomes 4 | 0.0273135 |
| KIF5B | kinesin family member 5B | 0.0272359 |
| TMEM41B | transmembrane protein 41B | 0.0271142 |
| HDGF | hepatoma-derived growth factor | 0.0271122 |
| BCLAF1 | BCL2-associated transcription factor 1 | 0.0269654 |
| RPL5 | ribosomal protein L5 | 0.0269002 |
| TMSB4X | thymosin beta 4, X-linked | 0.0266487 |
| HMGB2 | high mobility group box 2 | 0.0266462 |
| HIF1A | hypoxia inducible factor 1, alpha subunit (basic helix-loop-helix transcription factor) | 0.0264072 |
| TCEA1 | transcription elongation factor A (SII), 1 | 0.0263988 |
| DNAJC5 | DnaJ (Hsp40) homolog, subfamily C, member 5 | 0.0261923 |
| SUCO | SUN domain containing ossification factor | 0.026162 |
| UBC | ubiquitin C | 0.0261517 |
| CYP51A1 | cytochrome P450, family 51, subfamily A, polypeptide 1 | 0.0258207 |
| CD46 | CD46 molecule, complement regulatory protein | 0.0256585 |
| ACTR3 | ARP3 actin-related protein 3 homolog (yeast) | 0.025585 |
| TMED10 | transmembrane emp24-like trafficking protein 10 (yeast) | 0.0254365 |
| FOS | FBJ murine osteosarcoma viral oncogene homolog | 0.0251719 |
| Symbol | Name | Standardized Value |
|---|---|---|
| PTMA | prothymosin, alpha | -0.17293 |
| HSPA5 | heat shock 70kDa protein 5 (glucose-regulated protein, 78kDa) | -0.17192 |
| ACTG1 | actin gamma 1 | -0.141064 |
| AHNAK | AHNAK nucleoprotein | -0.114542 |
| FTL | ferritin, light polypeptide | -0.114158 |
| SAMD4A | sterile alpha motif domain containing 4A | -0.11179 |
| LPP | LIM domain containing preferred translocation partner in lipoma | -0.097747 |
| LAMC2 | laminin, gamma 2 | -0.0850965 |
| EXT1 | exostosin glycosyltransferase 1 | -0.0844319 |
| FBXO32 | F-box protein 32 | -0.0715672 |
| TMSB10 | thymosin beta 10 | -0.0710289 |
| ZSWIM6 | zinc finger, SWIM-type containing 6 | -0.0661782 |
| TM4SF1 | transmembrane 4 L six family member 1 | -0.0657523 |
| PGK1 | phosphoglycerate kinase 1 | -0.0640077 |
| PARP14 | poly (ADP-ribose) polymerase family, member 14 | -0.0633653 |
| PLEC | plectin | -0.0630365 |
| WSB1 | WD repeat and SOCS box containing 1 | -0.0630125 |
| ITGA2 | integrin, alpha 2 (CD49B, alpha 2 subunit of VLA-2 receptor) | -0.0599016 |
| SDC4 | syndecan 4 | -0.0570086 |
| ALCAM | activated leukocyte cell adhesion molecule | -0.0559242 |
| PABPC1 | poly(A) binding protein, cytoplasmic 1 | -0.0558598 |
| LAMB3 | laminin, beta 3 | -0.055725 |
| S100A10 | S100 calcium binding protein A10 | -0.0556306 |
| RNF213 | ring finger protein 213 | -0.0550611 |
| ANXA2 | annexin A2 | -0.0544163 |
| CTSB | cathepsin B | -0.0537321 |
| IFI16 | interferon, gamma-inducible protein 16 | -0.0523298 |
| KRT7 | keratin 7, type II | -0.0516302 |
| GAPDH | glyceraldehyde-3-phosphate dehydrogenase | -0.0508041 |
| CALR | calreticulin | -0.0504876 |
| GNB1 | guanine nucleotide binding protein (G protein), beta polypeptide 1 | -0.0481428 |
| CCND1 | cyclin D1 | -0.0467321 |
| RPL8 | ribosomal protein L8 | -0.046691 |
| H1-0 | H1.0 linker histone | -0.0455474 |
| EFNA5 | ephrin-A5 | -0.0447721 |
| MX2 | MX dynamin-like GTPase 2 | -0.0424007 |
| MARCHF6 | membrane associated ring-CH-type finger 6 | -0.042388 |
| VCL | vinculin | -0.0423298 |
| IGFBP3 | insulin-like growth factor binding protein 3 | -0.0406402 |
| PLAU | plasminogen activator, urokinase | -0.0406344 |
| GNAS | GNAS complex locus | -0.0406286 |
| RAB7A | RAB7A, member RAS oncogene family | -0.0406176 |
| NEDD4L | neural precursor cell expressed, developmentally down-regulated 4-like, E3 ubiquitin protein ligase | -0.0391134 |
| TEAD1 | TEA domain family member 1 (SV40 transcriptional enhancer factor) | -0.0390705 |
| RIGI | RNA sensor RIG-I | -0.0385851 |
| ARID4B | AT rich interactive domain 4B (RBP1-like) | -0.0385667 |
| SMURF2 | SMAD specific E3 ubiquitin protein ligase 2 | -0.0385494 |
| DSG2 | desmoglein 2 | -0.0383541 |
| ZNF207 | zinc finger protein 207 | -0.0382488 |
| PGBD5 | piggyBac transposable element derived 5 | -0.0379736 |
| MCU | mitochondrial calcium uniporter | -0.0375876 |
| SVIL | supervillin | -0.0375671 |
| MAP3K13 | mitogen-activated protein kinase kinase kinase 13 | -0.0372236 |
| ZC3HAV1 | zinc finger CCCH-type, antiviral 1 | -0.0368544 |
| MICAL3 | microtubule associated monooxygenase, calponin and LIM domain containing 3 | -0.0365185 |
| KDM5B | lysine (K)-specific demethylase 5B | -0.0361432 |
| DDX60L | DEAD (Asp-Glu-Ala-Asp) box polypeptide 60-like | -0.036023 |
| SH3KBP1 | SH3-domain kinase binding protein 1 | -0.0360142 |
| ABL2 | ABL proto-oncogene 2, non-receptor tyrosine kinase | -0.0354802 |
| FBXO34 | F-box protein 34 | -0.0354534 |
| ABTB2 | ankyrin repeat and BTB (POZ) domain containing 2 | -0.0354029 |
| ARIH1 | ariadne RBR E3 ubiquitin protein ligase 1 | -0.0351715 |
| LOC112694756 | uncharaterized LOC112694756 | -0.0346436 |
| KDM3A | lysine (K)-specific demethylase 3A | -0.0346264 |
| ARHGAP20 | Rho GTPase activating protein 20 | -0.0344439 |
| ZBTB20 | zinc finger and BTB domain containing 20 | -0.0340454 |
| LMO7 | LIM domain 7 | -0.0334041 |
| ARHGEF3 | Rho guanine nucleotide exchange factor (GEF) 3 | -0.0327234 |
| RAB1A | RAB1A, member RAS oncogene family | -0.0326174 |
| RAB5A | RAB5A, member RAS oncogene family | -0.0325592 |
| SOX4 | SRY (sex determining region Y)-box 4 | -0.0325162 |
| RBM47 | RNA binding motif protein 47 | -0.0323874 |
| MT2A | metallothionein 2A | -0.0321919 |
| FBXO11 | F-box protein 11 | -0.0316533 |
| CTNND1 | catenin (cadherin-associated protein), delta 1 | -0.0316215 |
| HNRNPH1 | heterogeneous nuclear ribonucleoprotein H1 (H) | -0.0312459 |
| HLA-B | major histocompatibility complex, class I, B | -0.0311887 |
| NF1 | neurofibromin 1 | -0.0310688 |
| ETV6 | ets variant 6 | -0.031026 |
| MED13 | mediator complex subunit 13 | -0.0307416 |
| TPT1 | tumor protein, translationally-controlled 1 | -0.0305318 |
| CD2AP | CD2-associated protein | -0.0300016 |
| TIMP2 | TIMP metallopeptidase inhibitor 2 | -0.0299639 |
| UBR5 | ubiquitin protein ligase E3 component n-recognin 5 | -0.0299607 |
| PKM | pyruvate kinase, muscle | -0.0298379 |
| ASH1L | ash1 (absent, small, or homeotic)-like (Drosophila) | -0.0297373 |
| ACTN4 | actinin, alpha 4 | -0.0295552 |
| HNRNPU | heterogeneous nuclear ribonucleoprotein U (scaffold attachment factor A) | -0.0295527 |
| G0S2 | G0/G1 switch 2 | -0.0294537 |
| RBM39 | RNA binding motif protein 39 | -0.0294178 |
| LMNA | lamin A/C | -0.0292801 |
| TNFRSF21 | tumor necrosis factor receptor superfamily, member 21 | -0.0291277 |
| CAVIN1 | caveolae associated protein 1 | -0.0289539 |
| SPATS2L | spermatogenesis associated, serine-rich 2-like | -0.0288632 |
| SPSB1 | splA/ryanodine receptor domain and SOCS box containing 1 | -0.0283014 |
| INTS6 | integrator complex subunit 6 | -0.0282702 |
| UBE2H | ubiquitin-conjugating enzyme E2H | -0.0280586 |
| AHNAK2 | AHNAK nucleoprotein 2 | -0.0279782 |
| STAU1 | staufen double-stranded RNA binding protein 1 | -0.027951 |
| IFI6 | interferon, alpha-inducible protein 6 | -0.0278944 |
