| Dataset | Tahoe Therapeutics Tahoe 100M Perturbation Atlas |
| Category | transcriptomics |
| Type | cell type |
| Description | Erlotinib perturbation in NCI-H596 cell line (Tahoe Therapeutics) |
| Similar Terms | |
| Downloads & Tools |
200 genes differentially expressed following the Erlotinib_NCI-H596 drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| ITGA6 | integrin, alpha 6 | 0.145064 |
| P4HA1 | prolyl 4-hydroxylase, alpha polypeptide I | 0.105148 |
| PDE10A | phosphodiesterase 10A | 0.0963776 |
| TXNRD1 | thioredoxin reductase 1 | 0.0960871 |
| HSP90AB1 | heat shock protein 90kDa alpha (cytosolic), class B member 1 | 0.0854492 |
| NALF1 | NALCN channel auxiliary factor 1 | 0.0852151 |
| RERE | arginine-glutamic acid dipeptide (RE) repeats | 0.0818883 |
| ENO1 | enolase 1, (alpha) | 0.0811229 |
| GNAS | GNAS complex locus | 0.078782 |
| GBE1 | glucan (1,4-alpha-), branching enzyme 1 | 0.0769338 |
| TOP1 | topoisomerase (DNA) I | 0.0745168 |
| MMAB | methylmalonic aciduria (cobalamin deficiency) cblB type | 0.0714559 |
| HSP90AA1 | heat shock protein 90kDa alpha (cytosolic), class A member 1 | 0.0657148 |
| RPL12 | ribosomal protein L12 | 0.065441 |
| HSPA5 | heat shock 70kDa protein 5 (glucose-regulated protein, 78kDa) | 0.0650114 |
| GARS1 | glycyl-tRNA synthetase 1 | 0.063335 |
| RBM33 | RNA binding motif protein 33 | 0.0630673 |
| BHLHE40 | basic helix-loop-helix family, member e40 | 0.0594534 |
| SMC4 | structural maintenance of chromosomes 4 | 0.0593525 |
| PKN2 | protein kinase N2 | 0.0576271 |
| PKM | pyruvate kinase, muscle | 0.0564609 |
| FNDC3A | fibronectin type III domain containing 3A | 0.0551626 |
| PTK2 | protein tyrosine kinase 2 | 0.0547948 |
| EXT1 | exostosin glycosyltransferase 1 | 0.0506496 |
| CDC42BPA | CDC42 binding protein kinase alpha (DMPK-like) | 0.050151 |
| COL5A2 | collagen, type V, alpha 2 | 0.0498572 |
| NPM1 | nucleophosmin (nucleolar phosphoprotein B23, numatrin) | 0.0486306 |
| ETNK1 | ethanolamine kinase 1 | 0.0477492 |
| ZNF638 | zinc finger protein 638 | 0.0464789 |
| RABGAP1L | RAB GTPase activating protein 1-like | 0.0454201 |
| TENM3 | teneurin transmembrane protein 3 | 0.045338 |
| PLCB1 | phospholipase C, beta 1 (phosphoinositide-specific) | 0.0441419 |
| ARHGEF12 | Rho guanine nucleotide exchange factor (GEF) 12 | 0.04267 |
| CADPS2 | Ca++-dependent secretion activator 2 | 0.0418129 |
| TRA2A | transformer 2 alpha homolog (Drosophila) | 0.0414246 |
| YAP1 | Yes-associated protein 1 | 0.0405755 |
| ZNF292 | zinc finger protein 292 | 0.0402432 |
| SYT1 | synaptotagmin I | 0.0400738 |
| PSD3 | pleckstrin and Sec7 domain containing 3 | 0.0394373 |
| TTC3 | tetratricopeptide repeat domain 3 | 0.0392792 |
| SPTBN1 | spectrin, beta, non-erythrocytic 1 | 0.0388739 |
| SMCHD1 | structural maintenance of chromosomes flexible hinge domain containing 1 | 0.038768 |
| MRTFA | myocardin related transcription factor A | 0.0385891 |
| FNIP1 | folliculin interacting protein 1 | 0.0385732 |
| FTL | ferritin, light polypeptide | 0.0375745 |
| RNF145 | ring finger protein 145 | 0.0364969 |
| P4HB | prolyl 4-hydroxylase, beta polypeptide | 0.0364095 |
| SNX13 | sorting nexin 13 | 0.0362071 |
| MKLN1 | muskelin 1, intracellular mediator containing kelch motifs | 0.0346779 |
| FAF1 | Fas (TNFRSF6) associated factor 1 | 0.0345052 |
| RNF213 | ring finger protein 213 | 0.0337451 |
| DYRK1A | dual-specificity tyrosine-(Y)-phosphorylation regulated kinase 1A | 0.0335627 |
| CLTC | clathrin, heavy chain (Hc) | 0.0329899 |
| PRRC2C | proline-rich coiled-coil 2C | 0.0329204 |
| KDM2A | lysine (K)-specific demethylase 2A | 0.0311056 |
| EPS8 | epidermal growth factor receptor pathway substrate 8 | 0.0305902 |
| ELL2 | elongation factor, RNA polymerase II, 2 | 0.0291176 |
| ZBTB20 | zinc finger and BTB domain containing 20 | 0.0283226 |
| USP34 | ubiquitin specific peptidase 34 | 0.0266905 |
| INHBA | inhibin, beta A | 0.0260545 |
| CMIP | c-Maf inducing protein | 0.0250328 |
| DLG1 | discs, large homolog 1 (Drosophila) | 0.0242642 |
| NCOA2 | nuclear receptor coactivator 2 | 0.0242209 |
| MYCBP2 | MYC binding protein 2, E3 ubiquitin protein ligase | 0.024115 |
| RPS3 | ribosomal protein S3 | 0.0240799 |
| PGK1 | phosphoglycerate kinase 1 | 0.0239952 |
| PPFIA1 | protein tyrosine phosphatase, receptor type, f polypeptide (PTPRF), interacting protein (liprin), alpha 1 | 0.0238465 |
| ANKRD11 | ankyrin repeat domain 11 | 0.023256 |
| CCNI | cyclin I | 0.0231982 |
| MMP1 | matrix metallopeptidase 1 | 0.0231686 |
| PIK3C2A | phosphatidylinositol-4-phosphate 3-kinase, catalytic subunit type 2 alpha | 0.0218593 |
| ERC2 | ELKS/RAB6-interacting/CAST family member 2 | 0.0203392 |
| KMT2E | lysine (K)-specific methyltransferase 2E | 0.019665 |
| ZFAND3 | zinc finger, AN1-type domain 3 | 0.0179445 |
| RPL11 | ribosomal protein L11 | 0.0173124 |
| MIER1 | mesoderm induction early response 1, transcriptional regulator | 0.0169952 |
| H3-3B | H3.3 histone B | 0.0168344 |
| TM9SF3 | transmembrane 9 superfamily member 3 | 0.0167853 |
| SLTM | SAFB-like, transcription modulator | 0.0158508 |
| TAX1BP1 | Tax1 (human T-cell leukemia virus type I) binding protein 1 | 0.0156921 |
| BIRC6 | baculoviral IAP repeat containing 6 | 0.015541 |
| SERPINE1 | serpin peptidase inhibitor, clade E (nexin, plasminogen activator inhibitor type 1), member 1 | 0.0146468 |
| MACF1 | microtubule-actin crosslinking factor 1 | 0.0136074 |
| POTEF | POTE ankyrin domain family, member F | 0.0133496 |
| IGF2 | insulin-like growth factor 2 | 0.0117723 |
| NCOA3 | nuclear receptor coactivator 3 | 0.0114506 |
| CARD16 | caspase recruitment domain family, member 16 | 0.0113049 |
| SQSTM1 | sequestosome 1 | 0.0112586 |
| LRRFIP1 | leucine rich repeat (in FLII) interacting protein 1 | 0.0111169 |
| ERRFI1 | ERBB receptor feedback inhibitor 1 | 0.0106927 |
| TBC1D22A | TBC1 domain family, member 22A | 0.00947431 |
| HMGA2 | high mobility group AT-hook 2 | 0.00905388 |
| RPL26 | ribosomal protein L26 | 0.00899315 |
| TPT1 | tumor protein, translationally-controlled 1 | 0.00854515 |
| RTN3 | reticulon 3 | 0.00710672 |
| ARB2A | ARB2 cotranscriptional regulator A | 0.00678354 |
| CD44 | CD44 molecule (Indian blood group) | 0.0061579 |
| UBE2D3 | ubiquitin-conjugating enzyme E2D 3 | 0.00611663 |
| ARID4B | AT rich interactive domain 4B (RBP1-like) | 0.00348584 |
| CENPF | centromere protein F, 350/400kDa | 0.00213677 |
| Symbol | Name | Standardized Value |
|---|---|---|
| GAPDH | glyceraldehyde-3-phosphate dehydrogenase | -0.197892 |
| VIM | vimentin | -0.185285 |
| ERO1A | endoplasmic reticulum oxidoreductase 1 alpha | -0.138074 |
| NAV2 | neuron navigator 2 | -0.11787 |
| GPC6 | glypican 6 | -0.10074 |
| PDE4D | phosphodiesterase 4D, cAMP-specific | -0.0913686 |
| PTMA | prothymosin, alpha | -0.0891077 |
| MT2A | metallothionein 2A | -0.0807964 |
| NAP1L1 | nucleosome assembly protein 1-like 1 | -0.0795953 |
| EIF1 | eukaryotic translation initiation factor 1 | -0.0727157 |
| CD55 | CD55 molecule, decay accelerating factor for complement (Cromer blood group) | -0.0723692 |
| EFNA5 | ephrin-A5 | -0.0722855 |
| MCL1 | myeloid cell leukemia 1 | -0.0708899 |
| TRIO | trio Rho guanine nucleotide exchange factor | -0.0679113 |
| MAML2 | mastermind-like 2 (Drosophila) | -0.0674382 |
| IGFBP3 | insulin-like growth factor binding protein 3 | -0.0669676 |
| RBPJ | recombination signal binding protein for immunoglobulin kappa J region | -0.0620066 |
| NKD1 | naked cuticle homolog 1 (Drosophila) | -0.0594355 |
| AKAP12 | A kinase (PRKA) anchor protein 12 | -0.0575585 |
| DST | dystonin | -0.0570576 |
| NF1 | neurofibromin 1 | -0.0568132 |
| RPS12 | ribosomal protein S12 | -0.056726 |
| MAGI2 | membrane associated guanylate kinase, WW and PDZ domain containing 2 | -0.0561424 |
| SETD5 | SET domain containing 5 | -0.0545755 |
| RLF | rearranged L-myc fusion | -0.0540884 |
| SEMA3A | sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3A | -0.0539181 |
| TANC2 | tetratricopeptide repeat, ankyrin repeat and coiled-coil containing 2 | -0.0504723 |
| TMSB10 | thymosin beta 10 | -0.0491384 |
| JMJD1C | jumonji domain containing 1C | -0.0465571 |
| RUNX1 | runt-related transcription factor 1 | -0.043512 |
| MYOF | myoferlin | -0.0434923 |
| RPL35A | ribosomal protein L35a | -0.043176 |
| RPL19 | ribosomal protein L19 | -0.0428361 |
| HELZ | helicase with zinc finger | -0.0406378 |
| HNRNPA2B1 | heterogeneous nuclear ribonucleoprotein A2/B1 | -0.0367831 |
| ARIH1 | ariadne RBR E3 ubiquitin protein ligase 1 | -0.0361415 |
| RPS21 | ribosomal protein S21 | -0.0354045 |
| SLC38A2 | solute carrier family 38, member 2 | -0.0350923 |
| RPS6 | ribosomal protein S6 | -0.0339304 |
| RPL23 | ribosomal protein L23 | -0.0337533 |
| PTPN12 | protein tyrosine phosphatase, non-receptor type 12 | -0.0336322 |
| EGR1 | early growth response 1 | -0.0320939 |
| MDGA2 | MAM domain containing glycosylphosphatidylinositol anchor 2 | -0.031052 |
| SPAG9 | sperm associated antigen 9 | -0.030586 |
| AKAP9 | A kinase (PRKA) anchor protein 9 | -0.0303745 |
| FN1 | fibronectin 1 | -0.0303531 |
| CDH13 | cadherin 13 | -0.0302352 |
| DCBLD2 | discoidin, CUB and LCCL domain containing 2 | -0.0272525 |
| PITPNC1 | phosphatidylinositol transfer protein, cytoplasmic 1 | -0.0271835 |
| INTS6 | integrator complex subunit 6 | -0.0269322 |
| RAD51B | RAD51 paralog B | -0.0266208 |
| UBA6 | ubiquitin-like modifier activating enzyme 6 | -0.0265124 |
| NAMPT | nicotinamide phosphoribosyltransferase | -0.0254337 |
| PDLIM5 | PDZ and LIM domain 5 | -0.0252355 |
| PTPRM | protein tyrosine phosphatase, receptor type, M | -0.0245211 |
| SND1 | staphylococcal nuclease and tudor domain containing 1 | -0.0235582 |
| FMNL2 | formin-like 2 | -0.0230559 |
| IGF2BP2 | insulin-like growth factor 2 mRNA binding protein 2 | -0.0229066 |
| ANKRD12 | ankyrin repeat domain 12 | -0.0223249 |
| HSP90B1 | heat shock protein 90kDa beta (Grp94), member 1 | -0.0220887 |
| SEC31A | SEC31 homolog A (S. cerevisiae) | -0.0212598 |
| HDLBP | high density lipoprotein binding protein | -0.020823 |
| RBM39 | RNA binding motif protein 39 | -0.0204865 |
| LPP | LIM domain containing preferred translocation partner in lipoma | -0.0200778 |
| FAM13A | family with sequence similarity 13, member A | -0.0200022 |
| GMDS | GDP-mannose 4,6-dehydratase | -0.0183803 |
| NDRG1 | N-myc downstream regulated 1 | -0.0183012 |
| RPL37A | ribosomal protein L37a | -0.0178308 |
| AGAP1 | ArfGAP with GTPase domain, ankyrin repeat and PH domain 1 | -0.0173559 |
| COPB1 | coatomer protein complex, subunit beta 1 | -0.0168858 |
| COG5 | component of oligomeric golgi complex 5 | -0.0161291 |
| RPS8 | ribosomal protein S8 | -0.0155619 |
| ATP2B1 | ATPase, Ca++ transporting, plasma membrane 1 | -0.0145033 |
| BPTF | bromodomain PHD finger transcription factor | -0.0143475 |
| RPS19 | ribosomal protein S19 | -0.0142326 |
| LRBA | LPS-responsive vesicle trafficking, beach and anchor containing | -0.0135778 |
| KMT2C | lysine (K)-specific methyltransferase 2C | -0.0118113 |
| FTH1 | ferritin, heavy polypeptide 1 | -0.011629 |
| FNDC3B | fibronectin type III domain containing 3B | -0.011534 |
| GLS2 | glutaminase 2 (liver, mitochondrial) | -0.0115081 |
| PARD3 | par-3 family cell polarity regulator | -0.011347 |
| VCL | vinculin | -0.0100155 |
| LAMB3 | laminin, beta 3 | -0.00970262 |
| PABPC1 | poly(A) binding protein, cytoplasmic 1 | -0.00929891 |
| ROBO2 | roundabout, axon guidance receptor, homolog 2 (Drosophila) | -0.00910871 |
| MYO1E | myosin IE | -0.00897647 |
| PDPK1 | 3-phosphoinositide dependent protein kinase 1 | -0.00860019 |
| EEF2 | eukaryotic translation elongation factor 2 | -0.00849706 |
| SLC38A1 | solute carrier family 38, member 1 | -0.00829509 |
| ATXN1 | ataxin 1 | -0.00798438 |
| TSC22D2 | TSC22 domain family, member 2 | -0.00787571 |
| SBF2 | SET binding factor 2 | -0.0075697 |
| RNF216 | ring finger protein 216 | -0.00734193 |
| ACTG1 | actin gamma 1 | -0.00642066 |
| LDHA | lactate dehydrogenase A | -0.00635947 |
| MBD5 | methyl-CpG binding domain protein 5 | -0.00457866 |
| IMMP2L | IMP2 inner mitochondrial membrane peptidase-like (S. cerevisiae) | -0.00445926 |
| OLA1 | Obg-like ATPase 1 | -0.00380564 |
| NFAT5 | nuclear factor of activated T-cells 5, tonicity-responsive | -0.00318541 |
| DSCAM | Down syndrome cell adhesion molecule | -0.00137699 |
