| Dataset | Tahoe Therapeutics Tahoe 100M Perturbation Atlas |
| Category | transcriptomics |
| Type | cell type |
| Description | Erlotinib perturbation in NCI-H661 cell line (Tahoe Therapeutics) |
| Similar Terms | |
| Downloads & Tools |
200 genes differentially expressed following the Erlotinib_NCI-H661 drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| KMT2C | lysine (K)-specific methyltransferase 2C | 0.033937 |
| ZNF292 | zinc finger protein 292 | 0.0318183 |
| SPAG9 | sperm associated antigen 9 | 0.026223 |
| WDR43 | WD repeat domain 43 | 0.0247468 |
| AKAP9 | A kinase (PRKA) anchor protein 9 | 0.0210866 |
| MIER1 | mesoderm induction early response 1, transcriptional regulator | 0.0191842 |
| TTC28 | tetratricopeptide repeat domain 28 | 0.0191533 |
| GPBP1 | GC-rich promoter binding protein 1 | 0.0179818 |
| CBX3 | chromobox homolog 3 | 0.0172826 |
| SLK | STE20-like kinase | 0.0172144 |
| MSN | moesin | 0.0171654 |
| TRIO | trio Rho guanine nucleotide exchange factor | 0.0158258 |
| KDM6A | lysine (K)-specific demethylase 6A | 0.0157305 |
| CFL2 | cofilin 2 (muscle) | 0.0156866 |
| MB21D2 | Mab-21 domain containing 2 | 0.0154903 |
| BZW1 | basic leucine zipper and W2 domains 1 | 0.0153218 |
| APLP2 | amyloid beta (A4) precursor-like protein 2 | 0.0147505 |
| EIF3A | eukaryotic translation initiation factor 3, subunit A | 0.0146444 |
| IL6ST | interleukin 6 signal transducer | 0.0145766 |
| NCKAP1 | NCK-associated protein 1 | 0.0145312 |
| AHCTF1 | AT hook containing transcription factor 1 | 0.0144467 |
| PNN | pinin, desmosome associated protein | 0.0143219 |
| U2SURP | U2 snRNP-associated SURP domain containing | 0.0142446 |
| ZC3HAV1 | zinc finger CCCH-type, antiviral 1 | 0.0142293 |
| MYO10 | myosin X | 0.0142077 |
| MAP4K4 | mitogen-activated protein kinase kinase kinase kinase 4 | 0.0140904 |
| CPNE8 | copine VIII | 0.0137888 |
| FOXG1 | forkhead box G1 | 0.0135591 |
| MGAT5 | mannosyl (alpha-1,6-)-glycoprotein beta-1,6-N-acetyl-glucosaminyltransferase | 0.0131768 |
| TCEA1 | transcription elongation factor A (SII), 1 | 0.0129909 |
| PAIP1 | poly(A) binding protein interacting protein 1 | 0.0127817 |
| EIF3E | eukaryotic translation initiation factor 3, subunit E | 0.0125688 |
| NLGN1 | neuroligin 1 | 0.0123219 |
| ATP11B | ATPase, class VI, type 11B | 0.0122692 |
| PPP4R1 | protein phosphatase 4, regulatory subunit 1 | 0.0122204 |
| PLEKHB2 | pleckstrin homology domain containing, family B (evectins) member 2 | 0.0120808 |
| ANKS1A | ankyrin repeat and sterile alpha motif domain containing 1A | 0.0119901 |
| ZDHHC20 | zinc finger, DHHC-type containing 20 | 0.011934 |
| PDIA6 | protein disulfide isomerase family A, member 6 | 0.0119163 |
| SEC63 | SEC63 homolog (S. cerevisiae) | 0.0117828 |
| CAPZA2 | capping protein (actin filament) muscle Z-line, alpha 2 | 0.011678 |
| SERINC1 | serine incorporator 1 | 0.011676 |
| POTEF | POTE ankyrin domain family, member F | 0.0115998 |
| NBAS | neuroblastoma amplified sequence | 0.011569 |
| LUC7L3 | LUC7-like 3 (S. cerevisiae) | 0.0114014 |
| DMXL1 | Dmx-like 1 | 0.0113232 |
| FBXO11 | F-box protein 11 | 0.0112779 |
| TBK1 | TANK-binding kinase 1 | 0.0112582 |
| PTPN13 | protein tyrosine phosphatase, non-receptor type 13 (APO-1/CD95 (Fas)-associated phosphatase) | 0.0112041 |
| CLINT1 | clathrin interactor 1 | 0.0111708 |
| TRPC4 | transient receptor potential cation channel, subfamily C, member 4 | 0.0110161 |
| PSAT1 | phosphoserine aminotransferase 1 | 0.0110096 |
| DNAJC10 | DnaJ (Hsp40) homolog, subfamily C, member 10 | 0.0110037 |
| PRPF40A | PRP40 pre-mRNA processing factor 40 homolog A (S. cerevisiae) | 0.0109966 |
| TARS1 | threonyl-tRNA synthetase 1 | 0.0109254 |
| CMSS1 | cms1 ribosomal small subunit homolog (yeast) | 0.0109238 |
| TMEM120B | transmembrane protein 120B | 0.0108954 |
| LEPROTL1 | leptin receptor overlapping transcript-like 1 | 0.0108771 |
| AUP1 | ancient ubiquitous protein 1 | 0.0108593 |
| SIN3A | SIN3 transcription regulator family member A | 0.010855 |
| UBE3A | ubiquitin protein ligase E3A | 0.0108048 |
| HERC5 | HECT and RLD domain containing E3 ubiquitin protein ligase 5 | 0.0107857 |
| SENP5 | SUMO1/sentrin specific peptidase 5 | 0.0107373 |
| NUP54 | nucleoporin 54kDa | 0.0107062 |
| PICALM | phosphatidylinositol binding clathrin assembly protein | 0.0106018 |
| SLC25A13 | solute carrier family 25 (aspartate/glutamate carrier), member 13 | 0.0104379 |
| EEF1G | eukaryotic translation elongation factor 1 gamma | 0.0104338 |
| SREK1 | splicing regulatory glutamine/lysine-rich protein 1 | 0.0103843 |
| THOC1 | THO complex 1 | 0.0103727 |
| STT3A | STT3A, subunit of the oligosaccharyltransferase complex (catalytic) | 0.0102233 |
| MYL9 | myosin, light chain 9, regulatory | 0.0101628 |
| GMFB | glia maturation factor, beta | 0.0101293 |
| ZC3H12B | zinc finger CCCH-type containing 12B | 0.0101114 |
| BIRC3 | baculoviral IAP repeat containing 3 | 0.0101093 |
| CNIH1 | cornichon family AMPA receptor auxiliary protein 1 | 0.0100957 |
| ANGPT1 | angiopoietin 1 | 0.0100325 |
| BIRC2 | baculoviral IAP repeat containing 2 | 0.0100132 |
| TMEM135 | transmembrane protein 135 | 0.00994482 |
| HNRNPH3 | heterogeneous nuclear ribonucleoprotein H3 (2H9) | 0.00993725 |
| VMP1 | vacuole membrane protein 1 | 0.00991731 |
| GAP43 | growth associated protein 43 | 0.00990625 |
| CERS6 | ceramide synthase 6 | 0.00990299 |
| IFIH1 | interferon induced with helicase C domain 1 | 0.00986782 |
| YWHAG | tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, gamma | 0.0098629 |
| PDS5B | PDS5 cohesin associated factor B | 0.00985069 |
| SRPK2 | SRSF protein kinase 2 | 0.00983093 |
| SFXN1 | sideroflexin 1 | 0.00981046 |
| UGCG | UDP-glucose ceramide glucosyltransferase | 0.00980779 |
| LAMP2 | lysosomal-associated membrane protein 2 | 0.00972225 |
| AKT3 | v-akt murine thymoma viral oncogene homolog 3 | 0.00971177 |
| SUMO1 | small ubiquitin-like modifier 1 | 0.00969258 |
| AFAP1 | actin filament associated protein 1 | 0.00966399 |
| CPAP | centrosome assembly and centriole elongation protein | 0.00966399 |
| TMEM106B | transmembrane protein 106B | 0.00962245 |
| ZDBF2 | zinc finger, DBF-type containing 2 | 0.00957825 |
| PNISR | PNN-interacting serine/arginine-rich protein | 0.00957619 |
| HADHA | hydroxyacyl-CoA dehydrogenase/3-ketoacyl-CoA thiolase/enoyl-CoA hydratase (trifunctional protein), alpha subunit | 0.00957169 |
| RAB18 | RAB18, member RAS oncogene family | 0.00956856 |
| FEM1C | fem-1 homolog c (C. elegans) | 0.00956684 |
| PALS1 | protein associated with LIN7 1, MAGUK p55 family member | 0.00956059 |
| Symbol | Name | Standardized Value |
|---|---|---|
| COL11A1 | collagen, type XI, alpha 1 | -0.178769 |
| VIM | vimentin | -0.165066 |
| CDH6 | cadherin 6, type 2, K-cadherin (fetal kidney) | -0.129725 |
| PTMA | prothymosin, alpha | -0.11359 |
| GAPDH | glyceraldehyde-3-phosphate dehydrogenase | -0.102314 |
| CDH10 | cadherin 10, type 2 (T2-cadherin) | -0.101327 |
| HSP90B1 | heat shock protein 90kDa beta (Grp94), member 1 | -0.101008 |
| HSPA5 | heat shock 70kDa protein 5 (glucose-regulated protein, 78kDa) | -0.0996858 |
| COL5A2 | collagen, type V, alpha 2 | -0.0974841 |
| TMSB10 | thymosin beta 10 | -0.0931584 |
| ACTG1 | actin gamma 1 | -0.0826216 |
| HSP90AA1 | heat shock protein 90kDa alpha (cytosolic), class A member 1 | -0.0737075 |
| RPS16 | ribosomal protein S16 | -0.0718391 |
| ERBB4 | erb-b2 receptor tyrosine kinase 4 | -0.0714625 |
| NUCKS1 | nuclear casein kinase and cyclin-dependent kinase substrate 1 | -0.0706627 |
| ADGRL2 | adhesion G protein-coupled receptor L2 | -0.0689363 |
| PCDH9 | protocadherin 9 | -0.0672693 |
| PCLO | piccolo presynaptic cytomatrix protein | -0.0654145 |
| PABPC1 | poly(A) binding protein, cytoplasmic 1 | -0.0647846 |
| RPS8 | ribosomal protein S8 | -0.0646506 |
| GNAS | GNAS complex locus | -0.0641728 |
| RBMS3 | RNA binding motif, single stranded interacting protein 3 | -0.0627059 |
| RPLP1 | ribosomal protein, large, P1 | -0.0603358 |
| COL3A1 | collagen, type III, alpha 1 | -0.0596209 |
| MKI67 | marker of proliferation Ki-67 | -0.0534419 |
| HNRNPH1 | heterogeneous nuclear ribonucleoprotein H1 (H) | -0.0520144 |
| CALR | calreticulin | -0.0492493 |
| HNRNPU | heterogeneous nuclear ribonucleoprotein U (scaffold attachment factor A) | -0.0488204 |
| CADM2 | cell adhesion molecule 2 | -0.0486729 |
| WSB1 | WD repeat and SOCS box containing 1 | -0.0482928 |
| YWHAZ | tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, zeta | -0.0461941 |
| TPT1 | tumor protein, translationally-controlled 1 | -0.0461627 |
| MARCKS | myristoylated alanine-rich protein kinase C substrate | -0.0461304 |
| TPR | translocated promoter region, nuclear basket protein | -0.0459317 |
| MYL12B | myosin, light chain 12B, regulatory | -0.0458442 |
| PEG10 | paternally expressed 10 | -0.0443346 |
| RPL35A | ribosomal protein L35a | -0.0430999 |
| ROBO1 | roundabout, axon guidance receptor, homolog 1 (Drosophila) | -0.0429883 |
| HS3ST5 | heparan sulfate (glucosamine) 3-O-sulfotransferase 5 | -0.0427972 |
| CDH19 | cadherin 19, type 2 | -0.0425333 |
| FOXP2 | forkhead box P2 | -0.0423844 |
| IMMP2L | IMP2 inner mitochondrial membrane peptidase-like (S. cerevisiae) | -0.0417693 |
| BACH2 | BTB and CNC homology 1, basic leucine zipper transcription factor 2 | -0.0413685 |
| MEIS2 | Meis homeobox 2 | -0.041187 |
| TENM3 | teneurin transmembrane protein 3 | -0.0411351 |
| BMPR2 | bone morphogenetic protein receptor, type II (serine/threonine kinase) | -0.0403672 |
| HMGB1 | high mobility group box 1 | -0.0393509 |
| AHNAK | AHNAK nucleoprotein | -0.0392719 |
| RPL11 | ribosomal protein L11 | -0.0385777 |
| ACTN4 | actinin, alpha 4 | -0.0383741 |
| RPL19 | ribosomal protein L19 | -0.0364606 |
| TMSB4X | thymosin beta 4, X-linked | -0.0360632 |
| RPL31 | ribosomal protein L31 | -0.0358888 |
| HDAC9 | histone deacetylase 9 | -0.0358815 |
| YWHAB | tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, beta | -0.035681 |
| SMCHD1 | structural maintenance of chromosomes flexible hinge domain containing 1 | -0.0352346 |
| PHIP | pleckstrin homology domain interacting protein | -0.0352019 |
| POLR2A | polymerase (RNA) II (DNA directed) polypeptide A, 220kDa | -0.0348846 |
| FBL | fibrillarin | -0.0347219 |
| GNB1 | guanine nucleotide binding protein (G protein), beta polypeptide 1 | -0.0347139 |
| MAP1LC3B | microtubule-associated protein 1 light chain 3 beta | -0.0345801 |
| ANXA2 | annexin A2 | -0.0341553 |
| LOC102724023 | ES1 protein homolog, mitochondrial | -0.0340312 |
| DPYD | dihydropyrimidine dehydrogenase | -0.033967 |
| TRPS1 | trichorhinophalangeal syndrome I | -0.0339471 |
| ITGAV | integrin, alpha V | -0.0339098 |
| PLPP1 | phospholipid phosphatase 1 | -0.0337225 |
| RPS6 | ribosomal protein S6 | -0.033688 |
| DEK | DEK proto-oncogene | -0.0326099 |
| RBM39 | RNA binding motif protein 39 | -0.03231 |
| RPS24 | ribosomal protein S24 | -0.0323083 |
| HNRNPUL1 | heterogeneous nuclear ribonucleoprotein U-like 1 | -0.0320205 |
| BAZ1A | bromodomain adjacent to zinc finger domain, 1A | -0.0315602 |
| SRP72 | signal recognition particle 72kDa | -0.0314753 |
| STAG2 | stromal antigen 2 | -0.0312763 |
| THBS1 | thrombospondin 1 | -0.0304747 |
| ZFAND3 | zinc finger, AN1-type domain 3 | -0.0302187 |
| RLF | rearranged L-myc fusion | -0.0301812 |
| RPS19 | ribosomal protein S19 | -0.029922 |
| LDHA | lactate dehydrogenase A | -0.029056 |
| PDIA3 | protein disulfide isomerase family A, member 3 | -0.0288723 |
| HSPB1 | heat shock 27kDa protein 1 | -0.0283823 |
| FTL | ferritin, light polypeptide | -0.0282567 |
| RFPL4B | ret finger protein-like 4B | -0.0281635 |
| TFRC | transferrin receptor | -0.0280438 |
| BPTF | bromodomain PHD finger transcription factor | -0.0279873 |
| PTGES3 | prostaglandin E synthase 3 (cytosolic) | -0.0278495 |
| RPS25 | ribosomal protein S25 | -0.0271699 |
| ASH1L | ash1 (absent, small, or homeotic)-like (Drosophila) | -0.0270543 |
| GPC3 | glypican 3 | -0.0269499 |
| CHD1 | chromodomain helicase DNA binding protein 1 | -0.0269259 |
| PAFAH1B1 | platelet-activating factor acetylhydrolase 1b, regulatory subunit 1 (45kDa) | -0.0267097 |
| SF3B2 | splicing factor 3b, subunit 2, 145kDa | -0.0266068 |
| NIPBL | Nipped-B homolog (Drosophila) | -0.0264958 |
| ITGB1 | integrin, beta 1 (fibronectin receptor, beta polypeptide, antigen CD29 includes MDF2, MSK12) | -0.0263935 |
| PRTG | protogenin | -0.0263588 |
| CNRIP1 | cannabinoid receptor interacting protein 1 | -0.0262172 |
| RERE | arginine-glutamic acid dipeptide (RE) repeats | -0.0261047 |
| IRF2BP2 | interferon regulatory factor 2 binding protein 2 | -0.0260923 |
| RBM25 | RNA binding motif protein 25 | -0.0260563 |
