| Dataset | Tahoe Therapeutics Tahoe 100M Perturbation Atlas |
| Category | transcriptomics |
| Type | cell type |
| Description | Erlotinib perturbation in SW 1088 cell line (Tahoe Therapeutics) |
| Similar Terms | |
| Downloads & Tools |
200 genes differentially expressed following the Erlotinib_SW 1088 drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| B2M | beta-2-microglobulin | 0.0460779 |
| DHX15 | DEAH (Asp-Glu-Ala-His) box helicase 15 | 0.0322596 |
| NAV2 | neuron navigator 2 | 0.0316784 |
| YWHAG | tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, gamma | 0.0305783 |
| RNF145 | ring finger protein 145 | 0.0303943 |
| N4BP2L2 | NEDD4 binding protein 2-like 2 | 0.0289515 |
| AKAP13 | A kinase (PRKA) anchor protein 13 | 0.028847 |
| MBOAT2 | membrane bound O-acyltransferase domain containing 2 | 0.0287743 |
| NPEPPS | aminopeptidase puromycin sensitive | 0.0282589 |
| TMEM158 | transmembrane protein 158 (gene/pseudogene) | 0.0276883 |
| MYOF | myoferlin | 0.0269184 |
| FMNL2 | formin-like 2 | 0.0259761 |
| NUP58 | nucleoporin 58 | 0.0259751 |
| MSN | moesin | 0.0259137 |
| ZNF292 | zinc finger protein 292 | 0.0257576 |
| WTAP | Wilms tumor 1 associated protein | 0.0257061 |
| NBAS | neuroblastoma amplified sequence | 0.0255901 |
| CAPZA2 | capping protein (actin filament) muscle Z-line, alpha 2 | 0.0255078 |
| ITM2B | integral membrane protein 2B | 0.0253201 |
| HLA-A | major histocompatibility complex, class I, A | 0.0245019 |
| YWHAE | tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, epsilon | 0.0239569 |
| POTEF | POTE ankyrin domain family, member F | 0.0235548 |
| KIF1B | kinesin family member 1B | 0.0234972 |
| SCAF8 | SR-related CTD-associated factor 8 | 0.0233259 |
| MTF2 | metal response element binding transcription factor 2 | 0.0230386 |
| PPP2R5C | protein phosphatase 2, regulatory subunit B', gamma | 0.0229991 |
| EEF2 | eukaryotic translation elongation factor 2 | 0.0229795 |
| BUB3 | BUB3 mitotic checkpoint protein | 0.022851 |
| AVL9 | AVL9 homolog (S. cerevisiase) | 0.0225399 |
| RAB8B | RAB8B, member RAS oncogene family | 0.0224743 |
| SPPL3 | signal peptide peptidase like 3 | 0.0223896 |
| JARID2 | jumonji, AT rich interactive domain 2 | 0.0222735 |
| AFF1 | AF4/FMR2 family, member 1 | 0.022248 |
| VPS41 | vacuolar protein sorting 41 homolog (S. cerevisiae) | 0.0220296 |
| ATP13A3 | ATPase type 13A3 | 0.0219739 |
| RAPGEF6 | Rap guanine nucleotide exchange factor (GEF) 6 | 0.0218847 |
| PDSS2 | prenyl (decaprenyl) diphosphate synthase, subunit 2 | 0.0216373 |
| TAPBP | TAP binding protein (tapasin) | 0.0214599 |
| NF1 | neurofibromin 1 | 0.0214272 |
| RPS8 | ribosomal protein S8 | 0.0213221 |
| ERBIN | erbb2 interacting protein | 0.0211255 |
| SFTPA2 | surfactant protein A2 | 0.0210482 |
| TMCC1 | transmembrane and coiled-coil domain family 1 | 0.0210063 |
| ABCA5 | ATP-binding cassette, sub-family A (ABC1), member 5 | 0.02099 |
| SNX9 | sorting nexin 9 | 0.0209608 |
| LAMB3 | laminin, beta 3 | 0.02071 |
| IGFBP6 | insulin-like growth factor binding protein 6 | 0.0206874 |
| SCARB2 | scavenger receptor class B, member 2 | 0.0206273 |
| AP3B1 | adaptor-related protein complex 3, beta 1 subunit | 0.0206141 |
| HILPDA | hypoxia inducible lipid droplet-associated | 0.0202934 |
| YBX1 | Y box binding protein 1 | 0.0202145 |
| DDOST | dolichyl-diphosphooligosaccharide--protein glycosyltransferase subunit (non-catalytic) | 0.0201686 |
| TUT4 | terminal uridylyl transferase 4 | 0.020116 |
| ANKRD36 | ankyrin repeat domain 36 | 0.0200669 |
| ITGBL1 | integrin, beta-like 1 (with EGF-like repeat domains) | 0.0200414 |
| UBE3C | ubiquitin protein ligase E3C | 0.0199565 |
| TIMP1 | TIMP metallopeptidase inhibitor 1 | 0.0199534 |
| PIK3C2A | phosphatidylinositol-4-phosphate 3-kinase, catalytic subunit type 2 alpha | 0.0199526 |
| LRRFIP1 | leucine rich repeat (in FLII) interacting protein 1 | 0.0199103 |
| MAPK8 | mitogen-activated protein kinase 8 | 0.0199013 |
| NUCKS1 | nuclear casein kinase and cyclin-dependent kinase substrate 1 | 0.0198843 |
| PPP2R5E | protein phosphatase 2, regulatory subunit B', epsilon isoform | 0.0198665 |
| VPS72 | vacuolar protein sorting 72 homolog (S. cerevisiae) | 0.0197414 |
| SREK1 | splicing regulatory glutamine/lysine-rich protein 1 | 0.0195378 |
| HNRNPU | heterogeneous nuclear ribonucleoprotein U (scaffold attachment factor A) | 0.019477 |
| OSBPL9 | oxysterol binding protein-like 9 | 0.0194173 |
| DNAJC25 | DnaJ (Hsp40) homolog, subfamily C , member 25 | 0.0193949 |
| ZDHHC20 | zinc finger, DHHC-type containing 20 | 0.0193515 |
| RPS12 | ribosomal protein S12 | 0.0191489 |
| RAP1B | RAP1B, member of RAS oncogene family | 0.0191341 |
| B4GALT5 | UDP-Gal:betaGlcNAc beta 1,4- galactosyltransferase, polypeptide 5 | 0.0189397 |
| IL1RAP | interleukin 1 receptor accessory protein | 0.0188366 |
| RPS3 | ribosomal protein S3 | 0.0188241 |
| ZNF680 | zinc finger protein 680 | 0.0188125 |
| FNBP1 | formin binding protein 1 | 0.0188107 |
| OPTN | optineurin | 0.0187491 |
| RPL5 | ribosomal protein L5 | 0.0186893 |
| LGALS3BP | lectin, galactoside-binding, soluble, 3 binding protein | 0.0186502 |
| MLLT10 | myeloid/lymphoid or mixed-lineage leukemia (trithorax homolog, Drosophila); translocated to, 10 | 0.0185546 |
| PTPRA | protein tyrosine phosphatase, receptor type, A | 0.0184014 |
| ATG12 | autophagy related 12 | 0.0183877 |
| XRN2 | 5'-3' exoribonuclease 2 | 0.01828 |
| TIMP2 | TIMP metallopeptidase inhibitor 2 | 0.018234 |
| PSMD14 | proteasome (prosome, macropain) 26S subunit, non-ATPase, 14 | 0.0182212 |
| TOP2A | topoisomerase (DNA) II alpha 170kDa | 0.0182092 |
| RPL28 | ribosomal protein L28 | 0.0180984 |
| NT5C3A | 5'-nucleotidase, cytosolic IIIA | 0.0179595 |
| CEP170 | centrosomal protein 170kDa | 0.0179394 |
| FUBP1 | far upstream element (FUSE) binding protein 1 | 0.0179312 |
| NHSL1 | NHS-like 1 | 0.0178816 |
| HYCC1 | hyccin PI4KA lipid kinase complex subunit 1 | 0.0178295 |
| TNPO1 | transportin 1 | 0.0176404 |
| FNTA | farnesyltransferase, CAAX box, alpha | 0.0176344 |
| FSCN1 | fascin actin-bundling protein 1 | 0.0175906 |
| IBTK | inhibitor of Bruton agammaglobulinemia tyrosine kinase | 0.0175319 |
| CST3 | cystatin C | 0.017489 |
| FRMD6 | FERM domain containing 6 | 0.0174754 |
| SBF2 | SET binding factor 2 | 0.0174591 |
| PRPF4B | pre-mRNA processing factor 4B | 0.017456 |
| HIVEP2 | human immunodeficiency virus type I enhancer binding protein 2 | 0.0174389 |
| Symbol | Name | Standardized Value |
|---|---|---|
| COL6A3 | collagen, type VI, alpha 3 | -0.2592 |
| IGFBP3 | insulin-like growth factor binding protein 3 | -0.243779 |
| GAPDH | glyceraldehyde-3-phosphate dehydrogenase | -0.203612 |
| LOX | lysyl oxidase | -0.113581 |
| EXT1 | exostosin glycosyltransferase 1 | -0.103119 |
| FN1 | fibronectin 1 | -0.102716 |
| PSD3 | pleckstrin and Sec7 domain containing 3 | -0.0988863 |
| NDRG1 | N-myc downstream regulated 1 | -0.0973968 |
| COL1A1 | collagen, type I, alpha 1 | -0.0955711 |
| TGFBI | transforming growth factor, beta-induced, 68kDa | -0.0930261 |
| ERRFI1 | ERBB receptor feedback inhibitor 1 | -0.0919244 |
| SERPINE1 | serpin peptidase inhibitor, clade E (nexin, plasminogen activator inhibitor type 1), member 1 | -0.0886357 |
| F3 | coagulation factor III (thromboplastin, tissue factor) | -0.0822001 |
| HSPA5 | heat shock 70kDa protein 5 (glucose-regulated protein, 78kDa) | -0.0730179 |
| CALU | calumenin | -0.0719071 |
| CANX | calnexin | -0.0718157 |
| CYP1B1 | cytochrome P450, family 1, subfamily B, polypeptide 1 | -0.0710213 |
| ENO1 | enolase 1, (alpha) | -0.0689776 |
| ANXA2 | annexin A2 | -0.0677209 |
| KCNMA1 | potassium channel, calcium activated large conductance subfamily M alpha, member 1 | -0.065222 |
| CALD1 | caldesmon 1 | -0.0648135 |
| PHLDA1 | pleckstrin homology-like domain, family A, member 1 | -0.0646907 |
| HSP90B1 | heat shock protein 90kDa beta (Grp94), member 1 | -0.0624219 |
| GLIS3 | GLIS family zinc finger 3 | -0.061883 |
| PLOD2 | procollagen-lysine, 2-oxoglutarate 5-dioxygenase 2 | -0.0594053 |
| AHNAK | AHNAK nucleoprotein | -0.058103 |
| CAV1 | caveolin 1, caveolae protein, 22kDa | -0.0565461 |
| TIMP3 | TIMP metallopeptidase inhibitor 3 | -0.0554629 |
| SEMA5A | sema domain, seven thrombospondin repeats (type 1 and type 1-like), transmembrane domain (TM) and short cytoplasmic domain, (semaphorin) 5A | -0.0530325 |
| ARRDC3 | arrestin domain containing 3 | -0.0518019 |
| ITGB1 | integrin, beta 1 (fibronectin receptor, beta polypeptide, antigen CD29 includes MDF2, MSK12) | -0.0501674 |
| NRXN3 | neurexin 3 | -0.049468 |
| MEF2A | myocyte enhancer factor 2A | -0.0487472 |
| CD99 | CD99 molecule | -0.0452395 |
| GBE1 | glucan (1,4-alpha-), branching enzyme 1 | -0.0451447 |
| HIPK2 | homeodomain interacting protein kinase 2 | -0.0448224 |
| ITGA2 | integrin, alpha 2 (CD49B, alpha 2 subunit of VLA-2 receptor) | -0.0443452 |
| ASCC3 | activating signal cointegrator 1 complex subunit 3 | -0.04417 |
| COL1A2 | collagen, type I, alpha 2 | -0.0441313 |
| VCL | vinculin | -0.0437663 |
| STC2 | stanniocalcin 2 | -0.0435224 |
| AGAP1 | ArfGAP with GTPase domain, ankyrin repeat and PH domain 1 | -0.0434577 |
| MBD5 | methyl-CpG binding domain protein 5 | -0.0432265 |
| TPM4 | tropomyosin 4 | -0.0427249 |
| CDK6 | cyclin-dependent kinase 6 | -0.0420931 |
| TFPI | tissue factor pathway inhibitor (lipoprotein-associated coagulation inhibitor) | -0.0412955 |
| ADM | adrenomedullin | -0.0397138 |
| ITGA3 | integrin, alpha 3 (antigen CD49C, alpha 3 subunit of VLA-3 receptor) | -0.0387965 |
| PAG1 | phosphoprotein membrane anchor with glycosphingolipid microdomains 1 | -0.0382195 |
| SPARC | secreted protein, acidic, cysteine-rich (osteonectin) | -0.0381225 |
| ANKRD17 | ankyrin repeat domain 17 | -0.0378278 |
| CD44 | CD44 molecule (Indian blood group) | -0.0378178 |
| CADM1 | cell adhesion molecule 1 | -0.0375378 |
| FAM13A | family with sequence similarity 13, member A | -0.037153 |
| PGK1 | phosphoglycerate kinase 1 | -0.0370735 |
| EFNA5 | ephrin-A5 | -0.036577 |
| MICAL2 | microtubule associated monooxygenase, calponin and LIM domain containing 2 | -0.0364647 |
| EPAS1 | endothelial PAS domain protein 1 | -0.0364192 |
| TXNIP | thioredoxin interacting protein | -0.0362674 |
| MT2A | metallothionein 2A | -0.0361053 |
| WSB1 | WD repeat and SOCS box containing 1 | -0.035561 |
| BNIP3L | BCL2/adenovirus E1B 19kDa interacting protein 3-like | -0.0354304 |
| VIM | vimentin | -0.0354226 |
| DPYD | dihydropyrimidine dehydrogenase | -0.0352052 |
| ADNP | activity-dependent neuroprotector homeobox | -0.0351867 |
| DDX17 | DEAD (Asp-Glu-Ala-Asp) box helicase 17 | -0.033842 |
| TNS3 | tensin 3 | -0.0338103 |
| BIRC6 | baculoviral IAP repeat containing 6 | -0.0330915 |
| RRBP1 | ribosome binding protein 1 | -0.0328154 |
| BRWD3 | bromodomain and WD repeat domain containing 3 | -0.0327127 |
| ATXN1 | ataxin 1 | -0.0325902 |
| SERPINE2 | serpin peptidase inhibitor, clade E (nexin, plasminogen activator inhibitor type 1), member 2 | -0.0325669 |
| TBC1D23 | TBC1 domain family, member 23 | -0.0324115 |
| GNB1 | guanine nucleotide binding protein (G protein), beta polypeptide 1 | -0.0322112 |
| PRKRIP1 | PRKR interacting protein 1 (IL11 inducible) | -0.0320338 |
| ASPH | aspartate beta-hydroxylase | -0.0320228 |
| LMAN1 | lectin, mannose-binding, 1 | -0.031628 |
| KAZN | kazrin, periplakin interacting protein | -0.0313611 |
| WDR26 | WD repeat domain 26 | -0.0310998 |
| EXOC4 | exocyst complex component 4 | -0.0308546 |
| LOC112694756 | uncharaterized LOC112694756 | -0.030838 |
| AFF4 | AF4/FMR2 family, member 4 | -0.0295017 |
| MAP1B | microtubule-associated protein 1B | -0.0290362 |
| RAB31 | RAB31, member RAS oncogene family | -0.0289068 |
| H3-3B | H3.3 histone B | -0.0284839 |
| H1-0 | H1.0 linker histone | -0.0284252 |
| HSP90AA1 | heat shock protein 90kDa alpha (cytosolic), class A member 1 | -0.0284226 |
| HIP1 | huntingtin interacting protein 1 | -0.0283178 |
| COL6A2 | collagen, type VI, alpha 2 | -0.0281701 |
| CCT6A | chaperonin containing TCP1, subunit 6A (zeta 1) | -0.0279519 |
| PRSS23 | protease, serine, 23 | -0.0276101 |
| RPS6KC1 | ribosomal protein S6 kinase, 52kDa, polypeptide 1 | -0.0272753 |
| P4HB | prolyl 4-hydroxylase, beta polypeptide | -0.0271307 |
| RAB27A | RAB27A, member RAS oncogene family | -0.0270825 |
| SCD | stearoyl-CoA desaturase (delta-9-desaturase) | -0.0270471 |
| MYO1E | myosin IE | -0.0270221 |
| RBMS3 | RNA binding motif, single stranded interacting protein 3 | -0.0267606 |
| VDAC1 | voltage-dependent anion channel 1 | -0.0267606 |
| LIMS1 | LIM and senescent cell antigen-like domains 1 | -0.0267477 |
| RNF24 | ring finger protein 24 | -0.0260729 |
