| Dataset | Tahoe Therapeutics Tahoe 100M Perturbation Atlas |
| Category | transcriptomics |
| Type | cell type |
| Description | Erlotinib perturbation in SW 900 cell line (Tahoe Therapeutics) |
| Similar Terms | |
| Downloads & Tools |
200 genes differentially expressed following the Erlotinib_SW 900 drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| PTGS2 | prostaglandin-endoperoxide synthase 2 (prostaglandin G/H synthase and cyclooxygenase) | 0.121176 |
| NAMPT | nicotinamide phosphoribosyltransferase | 0.0803481 |
| NPM1 | nucleophosmin (nucleolar phosphoprotein B23, numatrin) | 0.0791283 |
| CXCL8 | chemokine (C-X-C motif) ligand 8 | 0.0727596 |
| HSPA5 | heat shock 70kDa protein 5 (glucose-regulated protein, 78kDa) | 0.0658042 |
| CYP1B1 | cytochrome P450, family 1, subfamily B, polypeptide 1 | 0.0632871 |
| TRIO | trio Rho guanine nucleotide exchange factor | 0.0502717 |
| RPL26 | ribosomal protein L26 | 0.0465641 |
| FOS | FBJ murine osteosarcoma viral oncogene homolog | 0.0444873 |
| EREG | epiregulin | 0.0378748 |
| SUCO | SUN domain containing ossification factor | 0.0369749 |
| TXNRD1 | thioredoxin reductase 1 | 0.0364424 |
| FTH1 | ferritin, heavy polypeptide 1 | 0.036394 |
| RACK1 | receptor for activated C kinase 1 | 0.0346635 |
| BZW1 | basic leucine zipper and W2 domains 1 | 0.0335428 |
| AKAP9 | A kinase (PRKA) anchor protein 9 | 0.0330936 |
| SLC38A1 | solute carrier family 38, member 1 | 0.0316967 |
| CEP350 | centrosomal protein 350kDa | 0.0302308 |
| TPR | translocated promoter region, nuclear basket protein | 0.0299095 |
| EMP1 | epithelial membrane protein 1 | 0.028444 |
| TBC1D22A | TBC1 domain family, member 22A | 0.0283745 |
| DSTN | destrin (actin depolymerizing factor) | 0.0270739 |
| SEC31A | SEC31 homolog A (S. cerevisiae) | 0.0270464 |
| TMF1 | TATA element modulatory factor 1 | 0.0263517 |
| TIPARP | TCDD-inducible poly(ADP-ribose) polymerase | 0.0253846 |
| PRELID2 | PRELI domain containing 2 | 0.0251394 |
| TMSB4X | thymosin beta 4, X-linked | 0.0248863 |
| TAS2R14 | taste receptor, type 2, member 14 | 0.024776 |
| RPL31 | ribosomal protein L31 | 0.0244828 |
| FOSB | FBJ murine osteosarcoma viral oncogene homolog B | 0.0232004 |
| CDC42BPA | CDC42 binding protein kinase alpha (DMPK-like) | 0.0229218 |
| FAM13A | family with sequence similarity 13, member A | 0.0228932 |
| RLF | rearranged L-myc fusion | 0.0222531 |
| EZR | ezrin | 0.0218881 |
| RAD21 | RAD21 homolog (S. pombe) | 0.0217074 |
| ZC3H11A | zinc finger CCCH-type containing 11A | 0.0215206 |
| GPBP1 | GC-rich promoter binding protein 1 | 0.0214104 |
| YWHAG | tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, gamma | 0.0210818 |
| CSDE1 | cold shock domain containing E1, RNA-binding | 0.0206121 |
| RPS12 | ribosomal protein S12 | 0.0205736 |
| SF3B1 | splicing factor 3b, subunit 1, 155kDa | 0.0205564 |
| HSP90AB1 | heat shock protein 90kDa alpha (cytosolic), class B member 1 | 0.0203419 |
| RPL9 | ribosomal protein L9 | 0.0200574 |
| CARD16 | caspase recruitment domain family, member 16 | 0.0200046 |
| MYADM | myeloid-associated differentiation marker | 0.0194789 |
| MAP3K4 | mitogen-activated protein kinase kinase kinase 4 | 0.0193858 |
| SEC24D | SEC24 family member D | 0.01934 |
| BIRC3 | baculoviral IAP repeat containing 3 | 0.0187061 |
| MAPKAPK2 | mitogen-activated protein kinase-activated protein kinase 2 | 0.0186975 |
| SCLT1 | sodium channel and clathrin linker 1 | 0.0184903 |
| RPS5 | ribosomal protein S5 | 0.018445 |
| CRY1 | cryptochrome circadian clock 1 | 0.0182496 |
| GPRC5A | G protein-coupled receptor, class C, group 5, member A | 0.0181522 |
| GOLGB1 | golgin B1 | 0.0176758 |
| GBE1 | glucan (1,4-alpha-), branching enzyme 1 | 0.0176101 |
| BNIP3 | BCL2/adenovirus E1B 19kDa interacting protein 3 | 0.0174782 |
| PELI1 | pellino E3 ubiquitin protein ligase 1 | 0.0174008 |
| ARID4A | AT rich interactive domain 4A (RBP1-like) | 0.017395 |
| UBR2 | ubiquitin protein ligase E3 component n-recognin 2 | 0.0172276 |
| SERINC1 | serine incorporator 1 | 0.0172136 |
| PTPN11 | protein tyrosine phosphatase, non-receptor type 11 | 0.0172018 |
| TNFAIP2 | tumor necrosis factor, alpha-induced protein 2 | 0.0170156 |
| RPL11 | ribosomal protein L11 | 0.016895 |
| EYA1 | EYA transcriptional coactivator and phosphatase 1 | 0.0168595 |
| OPTN | optineurin | 0.016675 |
| RSRC1 | arginine/serine-rich coiled-coil 1 | 0.016589 |
| AP3B1 | adaptor-related protein complex 3, beta 1 subunit | 0.0165566 |
| NFATC2 | nuclear factor of activated T-cells, cytoplasmic, calcineurin-dependent 2 | 0.0165317 |
| OGFRL1 | opioid growth factor receptor-like 1 | 0.0164933 |
| IPMK | inositol polyphosphate multikinase | 0.0164843 |
| RPS2 | ribosomal protein S2 | 0.0164434 |
| TTC3 | tetratricopeptide repeat domain 3 | 0.0162601 |
| CXCL3 | chemokine (C-X-C motif) ligand 3 | 0.0162443 |
| NEBL | nebulette | 0.0161522 |
| CCDC186 | coiled-coil domain containing 186 | 0.0158983 |
| NFKBIZ | nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor, zeta | 0.0158436 |
| CALM2 | calmodulin 2 (phosphorylase kinase, delta) | 0.015838 |
| KAZN | kazrin, periplakin interacting protein | 0.015791 |
| ZC3H12C | zinc finger CCCH-type containing 12C | 0.0156276 |
| SIK3 | SIK family kinase 3 | 0.0155154 |
| GNAI1 | guanine nucleotide binding protein (G protein), alpha inhibiting activity polypeptide 1 | 0.0154637 |
| RPL30 | ribosomal protein L30 | 0.015285 |
| EGLN1 | egl-9 family hypoxia-inducible factor 1 | 0.0152703 |
| CLINT1 | clathrin interactor 1 | 0.015242 |
| HLA-E | major histocompatibility complex, class I, E | 0.0150874 |
| ABL2 | ABL proto-oncogene 2, non-receptor tyrosine kinase | 0.0149158 |
| LIFR | leukemia inhibitory factor receptor alpha | 0.0148466 |
| CRIM1 | cysteine rich transmembrane BMP regulator 1 (chordin-like) | 0.0148343 |
| MBNL2 | muscleblind-like splicing regulator 2 | 0.0148144 |
| ABLIM3 | actin binding LIM protein family, member 3 | 0.014684 |
| ARRDC3 | arrestin domain containing 3 | 0.014684 |
| GOLGA4 | golgin A4 | 0.0146119 |
| UBE3C | ubiquitin protein ligase E3C | 0.0145671 |
| CDC73 | cell division cycle 73 | 0.0145002 |
| NFE2L1 | nuclear factor, erythroid 2-like 1 | 0.0144099 |
| SEC61A1 | Sec61 alpha 1 subunit (S. cerevisiae) | 0.0143888 |
| CXCL1 | chemokine (C-X-C motif) ligand 1 (melanoma growth stimulating activity, alpha) | 0.0143788 |
| HERC1 | HECT and RLD domain containing E3 ubiquitin protein ligase family member 1 | 0.0143783 |
| CTBP2 | C-terminal binding protein 2 | 0.0143357 |
| SMC5 | structural maintenance of chromosomes 5 | 0.0140901 |
| Symbol | Name | Standardized Value |
|---|---|---|
| FN1 | fibronectin 1 | -0.248489 |
| GAPDH | glyceraldehyde-3-phosphate dehydrogenase | -0.183607 |
| MT2A | metallothionein 2A | -0.0966257 |
| NDRG1 | N-myc downstream regulated 1 | -0.0875827 |
| PTMA | prothymosin, alpha | -0.0859811 |
| PABPC1 | poly(A) binding protein, cytoplasmic 1 | -0.0826981 |
| ERO1A | endoplasmic reticulum oxidoreductase 1 alpha | -0.0800756 |
| NRG1 | neuregulin 1 | -0.0728551 |
| VCL | vinculin | -0.0702158 |
| PHLDA1 | pleckstrin homology-like domain, family A, member 1 | -0.0664947 |
| EXT1 | exostosin glycosyltransferase 1 | -0.062696 |
| ITGA2 | integrin, alpha 2 (CD49B, alpha 2 subunit of VLA-2 receptor) | -0.0621689 |
| HMGA2 | high mobility group AT-hook 2 | -0.0619764 |
| HIF1A | hypoxia inducible factor 1, alpha subunit (basic helix-loop-helix transcription factor) | -0.0531089 |
| WSB1 | WD repeat and SOCS box containing 1 | -0.0525718 |
| NRP1 | neuropilin 1 | -0.0524055 |
| HLA-B | major histocompatibility complex, class I, B | -0.051318 |
| ASPH | aspartate beta-hydroxylase | -0.048766 |
| ABCA1 | ATP-binding cassette, sub-family A (ABC1), member 1 | -0.0487637 |
| TXNIP | thioredoxin interacting protein | -0.0486883 |
| HNRNPH1 | heterogeneous nuclear ribonucleoprotein H1 (H) | -0.0471415 |
| CDH11 | cadherin 11, type 2, OB-cadherin (osteoblast) | -0.0468045 |
| RBPJ | recombination signal binding protein for immunoglobulin kappa J region | -0.044973 |
| KMT2E | lysine (K)-specific methyltransferase 2E | -0.0449475 |
| POLR2A | polymerase (RNA) II (DNA directed) polypeptide A, 220kDa | -0.044354 |
| TMSB10 | thymosin beta 10 | -0.0431007 |
| NTN4 | netrin 4 | -0.0427329 |
| RTN4 | reticulon 4 | -0.0420888 |
| FTL | ferritin, light polypeptide | -0.0415621 |
| PKM | pyruvate kinase, muscle | -0.041082 |
| OGA | O-GlcNAcase | -0.0410734 |
| ELL2 | elongation factor, RNA polymerase II, 2 | -0.0382904 |
| ETV1 | ets variant 1 | -0.0365392 |
| ZFP36L1 | ZFP36 ring finger protein-like 1 | -0.0362849 |
| PTBP3 | polypyrimidine tract binding protein 3 | -0.0349795 |
| RAB31 | RAB31, member RAS oncogene family | -0.0340693 |
| ACTN4 | actinin, alpha 4 | -0.0333278 |
| DCBLD2 | discoidin, CUB and LCCL domain containing 2 | -0.0332752 |
| ITGA3 | integrin, alpha 3 (antigen CD49C, alpha 3 subunit of VLA-3 receptor) | -0.0331663 |
| KDM5B | lysine (K)-specific demethylase 5B | -0.0328531 |
| RNF213 | ring finger protein 213 | -0.0327874 |
| HSP90B1 | heat shock protein 90kDa beta (Grp94), member 1 | -0.032338 |
| MYO10 | myosin X | -0.0322328 |
| IL6ST | interleukin 6 signal transducer | -0.031929 |
| FOXP1 | forkhead box P1 | -0.0316746 |
| FNDC3A | fibronectin type III domain containing 3A | -0.0316508 |
| SQSTM1 | sequestosome 1 | -0.0306542 |
| NHS | Nance-Horan syndrome (congenital cataracts and dental anomalies) | -0.0305548 |
| FNDC3B | fibronectin type III domain containing 3B | -0.03052 |
| TMEM156 | transmembrane protein 156 | -0.0301459 |
| GNB1 | guanine nucleotide binding protein (G protein), beta polypeptide 1 | -0.0299484 |
| IFI27 | interferon, alpha-inducible protein 27 | -0.0298353 |
| SETD5 | SET domain containing 5 | -0.029741 |
| OSMR | oncostatin M receptor | -0.0296844 |
| SLC25A37 | solute carrier family 25 (mitochondrial iron transporter), member 37 | -0.0295223 |
| TOP1 | topoisomerase (DNA) I | -0.0294871 |
| COPA | coatomer protein complex, subunit alpha | -0.0284289 |
| NRIP1 | nuclear receptor interacting protein 1 | -0.0279476 |
| PGK1 | phosphoglycerate kinase 1 | -0.0279343 |
| P4HB | prolyl 4-hydroxylase, beta polypeptide | -0.0267177 |
| ENO2 | enolase 2 (gamma, neuronal) | -0.0264739 |
| ATP2B1 | ATPase, Ca++ transporting, plasma membrane 1 | -0.0255564 |
| GNAS | GNAS complex locus | -0.0253044 |
| ARPC2 | actin related protein 2/3 complex, subunit 2, 34kDa | -0.0252617 |
| SPRED2 | sprouty-related, EVH1 domain containing 2 | -0.0250768 |
| PAFAH1B1 | platelet-activating factor acetylhydrolase 1b, regulatory subunit 1 (45kDa) | -0.025041 |
| IGFBP3 | insulin-like growth factor binding protein 3 | -0.0249486 |
| ANXA2 | annexin A2 | -0.0249469 |
| AKAP12 | A kinase (PRKA) anchor protein 12 | -0.0248568 |
| SMYD3 | SET and MYND domain containing 3 | -0.0247189 |
| PALLD | palladin, cytoskeletal associated protein | -0.0247127 |
| MKLN1 | muskelin 1, intracellular mediator containing kelch motifs | -0.02439 |
| PCBP2 | poly(rC) binding protein 2 | -0.0243375 |
| HMGB1 | high mobility group box 1 | -0.0243188 |
| TFPI | tissue factor pathway inhibitor (lipoprotein-associated coagulation inhibitor) | -0.0243093 |
| RERE | arginine-glutamic acid dipeptide (RE) repeats | -0.0241793 |
| ARID4B | AT rich interactive domain 4B (RBP1-like) | -0.024117 |
| SLC20A1 | solute carrier family 20 (phosphate transporter), member 1 | -0.0240913 |
| UGCG | UDP-glucose ceramide glucosyltransferase | -0.0240309 |
| YWHAZ | tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, zeta | -0.0239217 |
| GLIS3 | GLIS family zinc finger 3 | -0.0239061 |
| NR3C1 | nuclear receptor subfamily 3, group C, member 1 (glucocorticoid receptor) | -0.0238404 |
| CAPZA1 | capping protein (actin filament) muscle Z-line, alpha 1 | -0.0237787 |
| CPEB4 | cytoplasmic polyadenylation element binding protein 4 | -0.0236184 |
| TSC22D2 | TSC22 domain family, member 2 | -0.0234408 |
| WWTR1 | WW domain containing transcription regulator 1 | -0.0228363 |
| KMT2C | lysine (K)-specific methyltransferase 2C | -0.0227156 |
| TGFB1 | transforming growth factor, beta 1 | -0.0226061 |
| FHL2 | four and a half LIM domains 2 | -0.0222233 |
| NXN | nucleoredoxin | -0.0222159 |
| RNF24 | ring finger protein 24 | -0.0220075 |
| NPEPPS | aminopeptidase puromycin sensitive | -0.0217616 |
| SMURF2 | SMAD specific E3 ubiquitin protein ligase 2 | -0.0217063 |
| B4GALT5 | UDP-Gal:betaGlcNAc beta 1,4- galactosyltransferase, polypeptide 5 | -0.0216692 |
| GLUL | glutamate-ammonia ligase | -0.0216588 |
| FOXO3 | forkhead box O3 | -0.0215578 |
| KCMF1 | potassium channel modulatory factor 1 | -0.021471 |
| BMPR2 | bone morphogenetic protein receptor, type II (serine/threonine kinase) | -0.0214068 |
| LRP5 | low density lipoprotein receptor-related protein 5 | -0.0213962 |
| VIM | vimentin | -0.0213425 |
