Erythrocyte Indices Gene Set

Dataset dbGAP Gene-Trait Associations
Category disease or phenotype associations
Type trait
Description ERYTHROCYTE size and HEMOGLOBIN content or concentration, usually derived from ERYTHROCYTE COUNT; BLOOD hemoglobin concentration; and HEMATOCRIT. The indices include the mean corpuscular volume (MCV), the mean corpuscular hemoglobin (MCH), and the mean corpuscular hemoglobin concentration (MCHC). (Experimental Factor Ontology, EFO_0004306)
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Genes

51 genes associated with the trait Erythrocyte Indices in GWAS and other genetic association datasets from the dbGAP Gene-Trait Associations dataset.

Symbol Name Standardized Value
HFE hemochromatosis 1.87955
TMPRSS6 transmembrane protease, serine 6 1.82364
CCND3 cyclin D3 1.70411
RCL1 RNA terminal phosphate cyclase-like 1 1.40774
GALNTL6 polypeptide N-acetylgalactosaminyltransferase-like 6 1.35742
ODF3B outer dense fiber of sperm tails 3B 1.23281
ZNF286B zinc finger protein 286B 1.21882
PRKAG2 protein kinase, AMP-activated, gamma 2 non-catalytic subunit 1.20587
TFRC transferrin receptor 1.13511
IKZF1 IKAROS family zinc finger 1 (Ikaros) 1.09046
PRKCE protein kinase C, epsilon 1.0818
ITFG3 integrin alpha FG-GAP repeat containing 3 1.0562
GCDH glutaryl-CoA dehydrogenase 1.01477
HK1 hexokinase 1 0.995026
SPTA1 spectrin, alpha, erythrocytic 1 0.944178
MARCH8 membrane-associated ring finger (C3HC4) 8, E3 ubiquitin protein ligase 0.944178
CCDC162P coiled-coil domain containing 162, pseudogene 0.897125
NOVA1 neuro-oncological ventral antigen 1 0.832218
SLC17A1 solute carrier family 17 (organic anion transporter), member 1 0.685324
FNTB farnesyltransferase, CAAX box, beta 0.685324
MAX MYC associated factor X 0.685324
OR9G1 olfactory receptor, family 9, subfamily G, member 1 0.667558
ZFPM2 zinc finger protein, FOG family member 2 0.666389
MID1 midline 1 0.543393
KCNH8 potassium channel, voltage gated eag related subfamily H, member 8 0.503898
CCDC102B coiled-coil domain containing 102B 0.448941
TENM1 teneurin transmembrane protein 1 0.400433
ROBO2 roundabout, axon guidance receptor, homolog 2 (Drosophila) 0.398815
MEGF10 multiple EGF-like-domains 10 0.387475
DUSP27 dual specificity phosphatase 27 (putative) 0.363539
TNRC6B trinucleotide repeat containing 6B 0.342897
SLC25A37 solute carrier family 25 (mitochondrial iron transporter), member 37 0.337643
SLC39A11 solute carrier family 39, member 11 0.331178
NUDCD1 NudC domain containing 1 0.321516
ITGBL1 integrin, beta-like 1 (with EGF-like repeat domains) 0.315729
FIG4 FIG4 phosphoinositide 5-phosphatase 0.310838
WWTR1 WW domain containing transcription regulator 1 0.30881
CHAF1A chromatin assembly factor 1, subunit A (p150) 0.302952
CTNNA3 catenin (cadherin-associated protein), alpha 3 0.283111
ODF1 outer dense fiber of sperm tails 1 0.243661
PLXNC1 plexin C1 0.236582
GALNT13 polypeptide N-acetylgalactosaminyltransferase 13 0.172128
NOX3 NADPH oxidase 3 0.139944
SYNE1 spectrin repeat containing, nuclear envelope 1 0.112386
KCMF1 potassium channel modulatory factor 1 0.104447
PUS7 pseudouridylate synthase 7 (putative) 0.102489
HHAT hedgehog acyltransferase 0.101028
KCNJ6 potassium channel, inwardly rectifying subfamily J, member 6 0.066982
FNBP1L formin binding protein 1-like 0.062676
HNF1B HNF1 homeobox B 0.059727
PTPRQ protein tyrosine phosphatase, receptor type, Q 0.05875