| Dataset | Tahoe Therapeutics Tahoe 100M Perturbation Atlas |
| Category | transcriptomics |
| Type | cell type |
| Description | Erythromycin perturbation in A-172 cell line (Tahoe Therapeutics) |
| Similar Terms | |
| Downloads & Tools |
200 genes differentially expressed following the Erythromycin_A-172 drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| GAPDH | glyceraldehyde-3-phosphate dehydrogenase | 0.129075 |
| FTH1 | ferritin, heavy polypeptide 1 | 0.0772254 |
| BHLHE40 | basic helix-loop-helix family, member e40 | 0.0589557 |
| FNDC3B | fibronectin type III domain containing 3B | 0.0563413 |
| SQSTM1 | sequestosome 1 | 0.055109 |
| KCNMA1 | potassium channel, calcium activated large conductance subfamily M alpha, member 1 | 0.0528304 |
| DPYSL3 | dihydropyrimidinase-like 3 | 0.0514945 |
| UBC | ubiquitin C | 0.0513089 |
| OGA | O-GlcNAcase | 0.049939 |
| MXI1 | MAX interactor 1, dimerization protein | 0.0446475 |
| GOLGA4 | golgin A4 | 0.044627 |
| SOX9 | SRY (sex determining region Y)-box 9 | 0.042812 |
| STC1 | stanniocalcin 1 | 0.0421895 |
| FBN1 | fibrillin 1 | 0.0412957 |
| SBF2 | SET binding factor 2 | 0.0401495 |
| ELL2 | elongation factor, RNA polymerase II, 2 | 0.0400238 |
| TNFRSF10B | tumor necrosis factor receptor superfamily, member 10b | 0.0374535 |
| RPS6 | ribosomal protein S6 | 0.0372638 |
| TNIP1 | TNFAIP3 interacting protein 1 | 0.0371313 |
| NAP1L1 | nucleosome assembly protein 1-like 1 | 0.0370267 |
| P4HA1 | prolyl 4-hydroxylase, alpha polypeptide I | 0.0362154 |
| NAMPT | nicotinamide phosphoribosyltransferase | 0.0356533 |
| FMNL2 | formin-like 2 | 0.0352359 |
| SLC7A5 | solute carrier family 7 (amino acid transporter light chain, L system), member 5 | 0.0349997 |
| PABPC1 | poly(A) binding protein, cytoplasmic 1 | 0.0340623 |
| ESYT2 | extended synaptotagmin-like protein 2 | 0.0332848 |
| TRA2A | transformer 2 alpha homolog (Drosophila) | 0.0329565 |
| SERPINE2 | serpin peptidase inhibitor, clade E (nexin, plasminogen activator inhibitor type 1), member 2 | 0.0329528 |
| OPTN | optineurin | 0.0327954 |
| CLU | clusterin | 0.0326942 |
| GPC6 | glypican 6 | 0.0318149 |
| KMT2E | lysine (K)-specific methyltransferase 2E | 0.0316465 |
| C1D | C1D nuclear receptor corepressor | 0.0314547 |
| ATP13A3 | ATPase type 13A3 | 0.0313953 |
| SOD2 | superoxide dismutase 2, mitochondrial | 0.0303551 |
| LUC7L3 | LUC7-like 3 (S. cerevisiae) | 0.0303291 |
| ETS1 | v-ets avian erythroblastosis virus E26 oncogene homolog 1 | 0.0303047 |
| HIP1 | huntingtin interacting protein 1 | 0.0302543 |
| NFE2L1 | nuclear factor, erythroid 2-like 1 | 0.0299438 |
| ZFP36L1 | ZFP36 ring finger protein-like 1 | 0.0296433 |
| WDFY1 | WD repeat and FYVE domain containing 1 | 0.0294924 |
| POLR2A | polymerase (RNA) II (DNA directed) polypeptide A, 220kDa | 0.0294487 |
| HSP90AB1 | heat shock protein 90kDa alpha (cytosolic), class B member 1 | 0.0292351 |
| HELZ | helicase with zinc finger | 0.0288939 |
| EIF1 | eukaryotic translation initiation factor 1 | 0.0285456 |
| RTN4 | reticulon 4 | 0.0284744 |
| HILPDA | hypoxia inducible lipid droplet-associated | 0.0278452 |
| RNF24 | ring finger protein 24 | 0.0275387 |
| NFIX | nuclear factor I/X (CCAAT-binding transcription factor) | 0.0272506 |
| MYADM | myeloid-associated differentiation marker | 0.0271437 |
| KDM3A | lysine (K)-specific demethylase 3A | 0.0270098 |
| MIMS1 | mitochondrial inner membrane scaffold 1 | 0.0266614 |
| PHLDA1 | pleckstrin homology-like domain, family A, member 1 | 0.026546 |
| ADM | adrenomedullin | 0.0265416 |
| RICTOR | RPTOR independent companion of MTOR, complex 2 | 0.0264226 |
| ZMIZ1 | zinc finger, MIZ-type containing 1 | 0.0260988 |
| RPS2 | ribosomal protein S2 | 0.0252491 |
| BNIP3L | BCL2/adenovirus E1B 19kDa interacting protein 3-like | 0.0248822 |
| EGLN1 | egl-9 family hypoxia-inducible factor 1 | 0.0245727 |
| SLC22A23 | solute carrier family 22, member 23 | 0.0245178 |
| CD99 | CD99 molecule | 0.0239179 |
| RNMT | RNA (guanine-7-) methyltransferase | 0.0237652 |
| FHIP1A | FHF complex subunit HOOK interacting protein 1A | 0.0237371 |
| PTMA | prothymosin, alpha | 0.0237221 |
| DDIT4 | DNA-damage-inducible transcript 4 | 0.0237186 |
| MBNL2 | muscleblind-like splicing regulator 2 | 0.0237077 |
| SSBP2 | single-stranded DNA binding protein 2 | 0.0235113 |
| PML | promyelocytic leukemia | 0.022796 |
| SLC6A6 | solute carrier family 6 (neurotransmitter transporter), member 6 | 0.0226817 |
| TSC22D2 | TSC22 domain family, member 2 | 0.0221866 |
| ANKRD33B | ankyrin repeat domain 33B | 0.0221095 |
| LPCAT2 | lysophosphatidylcholine acyltransferase 2 | 0.022101 |
| WTAP | Wilms tumor 1 associated protein | 0.021664 |
| PPP1R15A | protein phosphatase 1, regulatory subunit 15A | 0.0214907 |
| GLS2 | glutaminase 2 (liver, mitochondrial) | 0.0214724 |
| MEF2A | myocyte enhancer factor 2A | 0.0214267 |
| RNF145 | ring finger protein 145 | 0.0210519 |
| CCNL1 | cyclin L1 | 0.0209423 |
| PSD3 | pleckstrin and Sec7 domain containing 3 | 0.0209344 |
| ZNF292 | zinc finger protein 292 | 0.0205969 |
| BRD4 | bromodomain containing 4 | 0.0204771 |
| EPAS1 | endothelial PAS domain protein 1 | 0.0203365 |
| PDK3 | pyruvate dehydrogenase kinase, isozyme 3 | 0.020146 |
| RYBP | RING1 and YY1 binding protein | 0.0201384 |
| CYLD | cylindromatosis (turban tumor syndrome) | 0.0198549 |
| CXXC5 | CXXC finger protein 5 | 0.0198292 |
| AP3S1 | adaptor-related protein complex 3, sigma 1 subunit | 0.0197617 |
| NT5C2 | 5'-nucleotidase, cytosolic II | 0.0195694 |
| RARA | retinoic acid receptor, alpha | 0.0195535 |
| MLLT10 | myeloid/lymphoid or mixed-lineage leukemia (trithorax homolog, Drosophila); translocated to, 10 | 0.0195443 |
| UBA6 | ubiquitin-like modifier activating enzyme 6 | 0.0194274 |
| MORC3 | MORC family CW-type zinc finger 3 | 0.0194136 |
| UGCG | UDP-glucose ceramide glucosyltransferase | 0.0194095 |
| UBE2O | ubiquitin-conjugating enzyme E2O | 0.0192793 |
| CD109 | CD109 molecule | 0.0192008 |
| SFTPA2 | surfactant protein A2 | 0.0192005 |
| YWHAQ | tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, theta | 0.0191663 |
| PCGF5 | polycomb group ring finger 5 | 0.0190415 |
| PER1 | period circadian clock 1 | 0.0190215 |
| SPNS2 | spinster homolog 2 (Drosophila) | 0.0187672 |
| Symbol | Name | Standardized Value |
|---|---|---|
| VIM | vimentin | -0.262388 |
| IGFBP3 | insulin-like growth factor binding protein 3 | -0.24761 |
| SPARC | secreted protein, acidic, cysteine-rich (osteonectin) | -0.215824 |
| ADAMTS6 | ADAM metallopeptidase with thrombospondin type 1 motif, 6 | -0.187361 |
| CDH13 | cadherin 13 | -0.180354 |
| KCNQ5 | potassium channel, voltage gated KQT-like subfamily Q, member 5 | -0.119949 |
| COL5A1 | collagen, type V, alpha 1 | -0.118971 |
| NAV1 | neuron navigator 1 | -0.115505 |
| SLC39A11 | solute carrier family 39, member 11 | -0.109736 |
| MAP1B | microtubule-associated protein 1B | -0.10246 |
| FN1 | fibronectin 1 | -0.0990031 |
| CACNA2D3 | calcium channel, voltage-dependent, alpha 2/delta subunit 3 | -0.0970323 |
| TMSB10 | thymosin beta 10 | -0.095623 |
| PODXL | podocalyxin-like | -0.0892443 |
| ABI3BP | ABI family, member 3 (NESH) binding protein | -0.0825912 |
| AHNAK | AHNAK nucleoprotein | -0.0798812 |
| PLAT | plasminogen activator, tissue | -0.0724764 |
| SUCNR1 | succinate receptor 1 | -0.0713032 |
| S100A10 | S100 calcium binding protein A10 | -0.0705156 |
| POTEF | POTE ankyrin domain family, member F | -0.0679913 |
| EGFR | epidermal growth factor receptor | -0.0674609 |
| SERPINE1 | serpin peptidase inhibitor, clade E (nexin, plasminogen activator inhibitor type 1), member 1 | -0.0671443 |
| PRSS23 | protease, serine, 23 | -0.0635914 |
| SAMD9 | sterile alpha motif domain containing 9 | -0.06109 |
| DIRAS3 | DIRAS family, GTP-binding RAS-like 3 | -0.0603116 |
| TPM4 | tropomyosin 4 | -0.0571222 |
| EFNA5 | ephrin-A5 | -0.0566527 |
| ASPH | aspartate beta-hydroxylase | -0.0509457 |
| CCND1 | cyclin D1 | -0.0503149 |
| RIGI | RNA sensor RIG-I | -0.0500837 |
| SLC38A1 | solute carrier family 38, member 1 | -0.0499968 |
| DGKG | diacylglycerol kinase, gamma 90kDa | -0.0493201 |
| S100A6 | S100 calcium binding protein A6 | -0.0481713 |
| PBX3 | pre-B-cell leukemia homeobox 3 | -0.047593 |
| DCLK2 | doublecortin-like kinase 2 | -0.0464857 |
| HSP90B1 | heat shock protein 90kDa beta (Grp94), member 1 | -0.0461407 |
| MACF1 | microtubule-actin crosslinking factor 1 | -0.0460807 |
| SEMA5A | sema domain, seven thrombospondin repeats (type 1 and type 1-like), transmembrane domain (TM) and short cytoplasmic domain, (semaphorin) 5A | -0.0448506 |
| CANX | calnexin | -0.0435499 |
| FLT1 | fms-related tyrosine kinase 1 | -0.0434562 |
| SORBS2 | sorbin and SH3 domain containing 2 | -0.0428131 |
| RPS6KA2 | ribosomal protein S6 kinase, 90kDa, polypeptide 2 | -0.0422841 |
| RSAD2 | radical S-adenosyl methionine domain containing 2 | -0.0417596 |
| HLA-B | major histocompatibility complex, class I, B | -0.0416817 |
| SIPA1L3 | signal-induced proliferation-associated 1 like 3 | -0.04076 |
| RNF213 | ring finger protein 213 | -0.0403657 |
| RABGEF1 | RAB guanine nucleotide exchange factor (GEF) 1 | -0.0389741 |
| COL5A2 | collagen, type V, alpha 2 | -0.038025 |
| PLXNA2 | plexin A2 | -0.0377346 |
| CALR | calreticulin | -0.0375847 |
| TRIO | trio Rho guanine nucleotide exchange factor | -0.0374796 |
| HS3ST3A1 | heparan sulfate (glucosamine) 3-O-sulfotransferase 3A1 | -0.0373792 |
| FRMD4A | FERM domain containing 4A | -0.0371011 |
| ZC3HAV1 | zinc finger CCCH-type, antiviral 1 | -0.0370795 |
| ITGA3 | integrin, alpha 3 (antigen CD49C, alpha 3 subunit of VLA-3 receptor) | -0.0370772 |
| TFPI | tissue factor pathway inhibitor (lipoprotein-associated coagulation inhibitor) | -0.0369457 |
| P4HB | prolyl 4-hydroxylase, beta polypeptide | -0.0367416 |
| LRRC17 | leucine rich repeat containing 17 | -0.0363501 |
| MAP4K4 | mitogen-activated protein kinase kinase kinase kinase 4 | -0.0359638 |
| COL8A1 | collagen, type VIII, alpha 1 | -0.0355003 |
| IL7R | interleukin 7 receptor | -0.0353303 |
| MX2 | MX dynamin-like GTPase 2 | -0.0347116 |
| IFIT2 | interferon-induced protein with tetratricopeptide repeats 2 | -0.0345808 |
| CUX1 | cut-like homeobox 1 | -0.0342646 |
| ABL2 | ABL proto-oncogene 2, non-receptor tyrosine kinase | -0.0339743 |
| TPM1 | tropomyosin 1 (alpha) | -0.0336091 |
| CYTH3 | cytohesin 3 | -0.033546 |
| HNRNPA2B1 | heterogeneous nuclear ribonucleoprotein A2/B1 | -0.0329087 |
| AKAP12 | A kinase (PRKA) anchor protein 12 | -0.0328052 |
| DKK3 | dickkopf WNT signaling pathway inhibitor 3 | -0.032227 |
| FSTL1 | follistatin-like 1 | -0.032096 |
| CD59 | CD59 molecule, complement regulatory protein | -0.0320725 |
| SPDL1 | spindle apparatus coiled-coil protein 1 | -0.031164 |
| LAMC1 | laminin, gamma 1 (formerly LAMB2) | -0.0310952 |
| TAGLN2 | transgelin 2 | -0.0309676 |
| PTPN14 | protein tyrosine phosphatase, non-receptor type 14 | -0.0291228 |
| EXT1 | exostosin glycosyltransferase 1 | -0.0289414 |
| TUBB4B | tubulin, beta 4B class IVb | -0.0288166 |
| HIVEP3 | human immunodeficiency virus type I enhancer binding protein 3 | -0.028703 |
| MRPS6 | mitochondrial ribosomal protein S6 | -0.0280076 |
| FMN2 | formin 2 | -0.0279419 |
| CDK6 | cyclin-dependent kinase 6 | -0.0279263 |
| KRT81 | keratin 81, type II | -0.027045 |
| DKK1 | dickkopf WNT signaling pathway inhibitor 1 | -0.0270024 |
| KIAA1549L | KIAA1549-like | -0.0268624 |
| CSTB | cystatin B (stefin B) | -0.0266949 |
| RASAL2 | RAS protein activator like 2 | -0.0266634 |
| RPS6KC1 | ribosomal protein S6 kinase, 52kDa, polypeptide 1 | -0.0264678 |
| BMPR2 | bone morphogenetic protein receptor, type II (serine/threonine kinase) | -0.0264322 |
| BRIP1 | BRCA1 interacting protein C-terminal helicase 1 | -0.0264314 |
| FEZ2 | fasciculation and elongation protein zeta 2 (zygin II) | -0.0261982 |
| ISG15 | ISG15 ubiquitin-like modifier | -0.0260375 |
| MAPKAP1 | mitogen-activated protein kinase associated protein 1 | -0.0258638 |
| OASL | 2'-5'-oligoadenylate synthetase-like | -0.0256637 |
| ANKRD11 | ankyrin repeat domain 11 | -0.0254716 |
| LRRFIP1 | leucine rich repeat (in FLII) interacting protein 1 | -0.0253783 |
| DOCK5 | dedicator of cytokinesis 5 | -0.0250789 |
| PDIA3 | protein disulfide isomerase family A, member 3 | -0.025036 |
| AGAP1 | ArfGAP with GTPase domain, ankyrin repeat and PH domain 1 | -0.0247798 |
| CD44 | CD44 molecule (Indian blood group) | -0.0246027 |
