| Dataset | Tahoe Therapeutics Tahoe 100M Perturbation Atlas |
| Category | transcriptomics |
| Type | cell type |
| Description | Erythromycin perturbation in A-427 cell line (Tahoe Therapeutics) |
| Similar Terms | |
| Downloads & Tools |
200 genes differentially expressed following the Erythromycin_A-427 drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| PTMA | prothymosin, alpha | 0.0962083 |
| NAP1L1 | nucleosome assembly protein 1-like 1 | 0.0836643 |
| HSP90AB1 | heat shock protein 90kDa alpha (cytosolic), class B member 1 | 0.0753435 |
| AKAP12 | A kinase (PRKA) anchor protein 12 | 0.0649791 |
| SERPINB2 | serpin peptidase inhibitor, clade B (ovalbumin), member 2 | 0.0619749 |
| HMGA2 | high mobility group AT-hook 2 | 0.0561334 |
| NLGN1 | neuroligin 1 | 0.049399 |
| ACTG1 | actin gamma 1 | 0.0484687 |
| PA2G4 | proliferation-associated 2G4, 38kDa | 0.0472054 |
| RPS2 | ribosomal protein S2 | 0.0440892 |
| RSL1D1 | ribosomal L1 domain containing 1 | 0.0417291 |
| MKI67 | marker of proliferation Ki-67 | 0.0397974 |
| TPI1 | triosephosphate isomerase 1 | 0.0397566 |
| H1-0 | H1.0 linker histone | 0.0395781 |
| TPT1 | tumor protein, translationally-controlled 1 | 0.0376437 |
| TUBA1B | tubulin, alpha 1b | 0.0375966 |
| NUCKS1 | nuclear casein kinase and cyclin-dependent kinase substrate 1 | 0.0368135 |
| CALR | calreticulin | 0.0363433 |
| ADIPOR2 | adiponectin receptor 2 | 0.0346187 |
| SMURF2 | SMAD specific E3 ubiquitin protein ligase 2 | 0.0332456 |
| IFIH1 | interferon induced with helicase C domain 1 | 0.0323626 |
| LOC102724023 | ES1 protein homolog, mitochondrial | 0.0314478 |
| PHLDA1 | pleckstrin homology-like domain, family A, member 1 | 0.0312186 |
| ROBO2 | roundabout, axon guidance receptor, homolog 2 (Drosophila) | 0.0311586 |
| CENPF | centromere protein F, 350/400kDa | 0.0300991 |
| FTH1 | ferritin, heavy polypeptide 1 | 0.029985 |
| RPL26 | ribosomal protein L26 | 0.0297713 |
| HSPA5 | heat shock 70kDa protein 5 (glucose-regulated protein, 78kDa) | 0.0293345 |
| EIF4G1 | eukaryotic translation initiation factor 4 gamma, 1 | 0.0287501 |
| NARS1 | asparaginyl-tRNA synthetase 1 | 0.0275706 |
| EGR1 | early growth response 1 | 0.0275389 |
| CCT5 | chaperonin containing TCP1, subunit 5 (epsilon) | 0.0273917 |
| DHX36 | DEAH (Asp-Glu-Ala-His) box polypeptide 36 | 0.0262776 |
| NAV3 | neuron navigator 3 | 0.0258099 |
| HDGF | hepatoma-derived growth factor | 0.025797 |
| PGAM4 | phosphoglycerate mutase family member 4 | 0.0243849 |
| GCG | glucagon | 0.0243393 |
| KPNB1 | karyopherin (importin) beta 1 | 0.0242811 |
| RPS8 | ribosomal protein S8 | 0.0239147 |
| SRGAP1 | SLIT-ROBO Rho GTPase activating protein 1 | 0.0238678 |
| DNMT1 | DNA (cytosine-5-)-methyltransferase 1 | 0.0232111 |
| GNAS | GNAS complex locus | 0.0226654 |
| RPL4 | ribosomal protein L4 | 0.0226163 |
| RPS7 | ribosomal protein S7 | 0.0226114 |
| HSPA8 | heat shock 70kDa protein 8 | 0.0221866 |
| CUX1 | cut-like homeobox 1 | 0.0217041 |
| UNC13A | unc-13 homolog A (C. elegans) | 0.0215797 |
| CALM2 | calmodulin 2 (phosphorylase kinase, delta) | 0.0212581 |
| MYPN | myopalladin | 0.0202368 |
| ASAP1 | ArfGAP with SH3 domain, ankyrin repeat and PH domain 1 | 0.0201784 |
| DNAJC5 | DnaJ (Hsp40) homolog, subfamily C, member 5 | 0.0200977 |
| EIF4H | eukaryotic translation initiation factor 4H | 0.0193973 |
| TGM2 | transglutaminase 2 | 0.0192072 |
| RPS6 | ribosomal protein S6 | 0.0191794 |
| CDK12 | cyclin-dependent kinase 12 | 0.0191585 |
| EZR | ezrin | 0.0190096 |
| EHBP1 | EH domain binding protein 1 | 0.0189486 |
| EPRS1 | glutamyl-prolyl-tRNA synthetase 1 | 0.0189197 |
| EIF2AK1 | eukaryotic translation initiation factor 2-alpha kinase 1 | 0.018819 |
| THRAP3 | thyroid hormone receptor associated protein 3 | 0.0187841 |
| GNB1 | guanine nucleotide binding protein (G protein), beta polypeptide 1 | 0.0187085 |
| RACK1 | receptor for activated C kinase 1 | 0.01846 |
| CREBBP | CREB binding protein | 0.0183683 |
| ARID1A | AT rich interactive domain 1A (SWI-like) | 0.0182067 |
| HADHA | hydroxyacyl-CoA dehydrogenase/3-ketoacyl-CoA thiolase/enoyl-CoA hydratase (trifunctional protein), alpha subunit | 0.0175759 |
| SET | SET nuclear proto-oncogene | 0.0174952 |
| HMGB2 | high mobility group box 2 | 0.0171444 |
| SSR3 | signal sequence receptor, gamma (translocon-associated protein gamma) | 0.0171386 |
| TM9SF4 | transmembrane 9 superfamily protein member 4 | 0.0170497 |
| ASPH | aspartate beta-hydroxylase | 0.0169626 |
| TPM4 | tropomyosin 4 | 0.0167496 |
| NPM1 | nucleophosmin (nucleolar phosphoprotein B23, numatrin) | 0.0167243 |
| RAD23A | RAD23 homolog A (S. cerevisiae) | 0.0166333 |
| YBX3 | Y box binding protein 3 | 0.0165037 |
| HNRNPAB | heterogeneous nuclear ribonucleoprotein A/B | 0.0163231 |
| BCLAF1 | BCL2-associated transcription factor 1 | 0.0162473 |
| PPP1R15A | protein phosphatase 1, regulatory subunit 15A | 0.0161838 |
| CHD4 | chromodomain helicase DNA binding protein 4 | 0.0160485 |
| VCAN | versican | 0.0160423 |
| BRIX1 | BRX1, biogenesis of ribosomes | 0.0158333 |
| FBXO27 | F-box protein 27 | 0.0158137 |
| PTPRF | protein tyrosine phosphatase, receptor type, F | 0.0158075 |
| BAZ2A | bromodomain adjacent to zinc finger domain, 2A | 0.0157425 |
| WDR43 | WD repeat domain 43 | 0.0155999 |
| PMEPA1 | prostate transmembrane protein, androgen induced 1 | 0.0155871 |
| LARP1 | La ribonucleoprotein domain family, member 1 | 0.0155454 |
| RAB7A | RAB7A, member RAS oncogene family | 0.0155357 |
| SNCA | synuclein, alpha (non A4 component of amyloid precursor) | 0.0151505 |
| RPS3 | ribosomal protein S3 | 0.0150359 |
| PTGES3 | prostaglandin E synthase 3 (cytosolic) | 0.0147982 |
| NFE2L1 | nuclear factor, erythroid 2-like 1 | 0.0147918 |
| NOLC1 | nucleolar and coiled-body phosphoprotein 1 | 0.0147746 |
| JUN | jun proto-oncogene | 0.0147516 |
| ANO6 | anoctamin 6 | 0.0146925 |
| SRRM2 | serine/arginine repetitive matrix 2 | 0.0144395 |
| BNIP3 | BCL2/adenovirus E1B 19kDa interacting protein 3 | 0.0143197 |
| TOP2A | topoisomerase (DNA) II alpha 170kDa | 0.0142573 |
| LRRC23 | leucine rich repeat containing 23 | 0.0142375 |
| PABPC4 | poly(A) binding protein, cytoplasmic 4 (inducible form) | 0.0140598 |
| LARS1 | leucyl-tRNA synthetase 1 | 0.0139859 |
| Symbol | Name | Standardized Value |
|---|---|---|
| AREG | amphiregulin | -0.202819 |
| TMSB10 | thymosin beta 10 | -0.153237 |
| VIM | vimentin | -0.140335 |
| PDE4D | phosphodiesterase 4D, cAMP-specific | -0.11742 |
| SLC2A3 | solute carrier family 2 (facilitated glucose transporter), member 3 | -0.115619 |
| TXNRD1 | thioredoxin reductase 1 | -0.102604 |
| ZBTB20 | zinc finger and BTB domain containing 20 | -0.0944987 |
| USP34 | ubiquitin specific peptidase 34 | -0.0713667 |
| ANKRD12 | ankyrin repeat domain 12 | -0.0666152 |
| ITGB1 | integrin, beta 1 (fibronectin receptor, beta polypeptide, antigen CD29 includes MDF2, MSK12) | -0.0664693 |
| ALDH1A1 | aldehyde dehydrogenase 1 family, member A1 | -0.0608643 |
| MDM2 | MDM2 proto-oncogene, E3 ubiquitin protein ligase | -0.059088 |
| CPOX | coproporphyrinogen oxidase | -0.0580758 |
| MMP12 | matrix metallopeptidase 12 | -0.0577719 |
| FXR1 | fragile X mental retardation, autosomal homolog 1 | -0.0543775 |
| FTL | ferritin, light polypeptide | -0.0541895 |
| HNRNPA2B1 | heterogeneous nuclear ribonucleoprotein A2/B1 | -0.0538192 |
| TMEM41B | transmembrane protein 41B | -0.0514033 |
| RPS19 | ribosomal protein S19 | -0.0493654 |
| BIRC6 | baculoviral IAP repeat containing 6 | -0.0487688 |
| YAP1 | Yes-associated protein 1 | -0.0484855 |
| VMP1 | vacuole membrane protein 1 | -0.0484072 |
| POLR2A | polymerase (RNA) II (DNA directed) polypeptide A, 220kDa | -0.048101 |
| PCM1 | pericentriolar material 1 | -0.0480506 |
| RB1CC1 | RB1-inducible coiled-coil 1 | -0.0478086 |
| NFAT5 | nuclear factor of activated T-cells 5, tonicity-responsive | -0.0467654 |
| ADGRG6 | adhesion G protein-coupled receptor G6 | -0.0463305 |
| BCAS3 | breast carcinoma amplified sequence 3 | -0.0455271 |
| EXOC6B | exocyst complex component 6B | -0.0451725 |
| TNPO1 | transportin 1 | -0.0447766 |
| PDE4B | phosphodiesterase 4B, cAMP-specific | -0.0444866 |
| NDUFV2 | NADH dehydrogenase (ubiquinone) flavoprotein 2, 24kDa | -0.0431067 |
| BIRC3 | baculoviral IAP repeat containing 3 | -0.0427366 |
| RAPGEF6 | Rap guanine nucleotide exchange factor (GEF) 6 | -0.0426249 |
| UAP1 | UDP-N-acetylglucosamine pyrophosphorylase 1 | -0.0425361 |
| ERC1 | ELKS/RAB6-interacting/CAST family member 1 | -0.0424978 |
| ATP5F1B | ATP synthase F1 subunit beta | -0.0414467 |
| AKT3 | v-akt murine thymoma viral oncogene homolog 3 | -0.0414311 |
| EIF4A2 | eukaryotic translation initiation factor 4A2 | -0.0408723 |
| SEMA3A | sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3A | -0.0403235 |
| MED13L | mediator complex subunit 13-like | -0.0403215 |
| TEAD1 | TEA domain family member 1 (SV40 transcriptional enhancer factor) | -0.0401556 |
| CNRIP1 | cannabinoid receptor interacting protein 1 | -0.039783 |
| DKK1 | dickkopf WNT signaling pathway inhibitor 1 | -0.0395185 |
| ERRFI1 | ERBB receptor feedback inhibitor 1 | -0.039083 |
| XPO1 | exportin 1 | -0.0387573 |
| RPS23 | ribosomal protein S23 | -0.0386549 |
| ATP11A | ATPase, class VI, type 11A | -0.0385518 |
| EPHA6 | EPH receptor A6 | -0.0383305 |
| CCNL1 | cyclin L1 | -0.0381569 |
| NEK7 | NIMA-related kinase 7 | -0.0378847 |
| PCDH7 | protocadherin 7 | -0.0377316 |
| RPLP1 | ribosomal protein, large, P1 | -0.0375923 |
| SBF2 | SET binding factor 2 | -0.0373627 |
| SLC38A2 | solute carrier family 38, member 2 | -0.0363306 |
| WWOX | WW domain containing oxidoreductase | -0.0359048 |
| EDN1 | endothelin 1 | -0.0359018 |
| CRISPLD1 | cysteine-rich secretory protein LCCL domain containing 1 | -0.0355448 |
| BPTF | bromodomain PHD finger transcription factor | -0.034994 |
| GFPT1 | glutamine--fructose-6-phosphate transaminase 1 | -0.0348453 |
| SMC4 | structural maintenance of chromosomes 4 | -0.034718 |
| CCSER1 | coiled-coil serine-rich protein 1 | -0.0345017 |
| PIK3CA | phosphatidylinositol-4,5-bisphosphate 3-kinase, catalytic subunit alpha | -0.034457 |
| TENM3 | teneurin transmembrane protein 3 | -0.0343469 |
| ERO1A | endoplasmic reticulum oxidoreductase 1 alpha | -0.0342968 |
| RPS5 | ribosomal protein S5 | -0.0341375 |
| GSK3B | glycogen synthase kinase 3 beta | -0.033797 |
| POTEF | POTE ankyrin domain family, member F | -0.0331671 |
| LRBA | LPS-responsive vesicle trafficking, beach and anchor containing | -0.0328053 |
| MON2 | MON2 homolog (S. cerevisiae) | -0.0327258 |
| KDM5A | lysine (K)-specific demethylase 5A | -0.0325714 |
| ATP11B | ATPase, class VI, type 11B | -0.0325104 |
| DDX5 | DEAD (Asp-Glu-Ala-Asp) box helicase 5 | -0.0317374 |
| NRXN3 | neurexin 3 | -0.0314704 |
| TBK1 | TANK-binding kinase 1 | -0.0314438 |
| SMCHD1 | structural maintenance of chromosomes flexible hinge domain containing 1 | -0.031376 |
| EPHA5 | EPH receptor A5 | -0.0312524 |
| CAMKMT | calmodulin-lysine N-methyltransferase | -0.0311201 |
| NFE2L2 | nuclear factor, erythroid 2-like 2 | -0.0309441 |
| TRA2B | transformer 2 beta homolog (Drosophila) | -0.0306237 |
| CEP95 | centrosomal protein 95kDa | -0.0305566 |
| PGK1 | phosphoglycerate kinase 1 | -0.030225 |
| PCBP2 | poly(rC) binding protein 2 | -0.0302218 |
| ETNK1 | ethanolamine kinase 1 | -0.0301793 |
| RPL23 | ribosomal protein L23 | -0.0301258 |
| IPO7 | importin 7 | -0.0299536 |
| CXADR | coxsackie virus and adenovirus receptor | -0.0297295 |
| RPS27 | ribosomal protein S27 | -0.0293241 |
| ACTR2 | ARP2 actin-related protein 2 homolog (yeast) | -0.0293053 |
| TBC1D5 | TBC1 domain family, member 5 | -0.0282511 |
| CEP192 | centrosomal protein 192kDa | -0.0282297 |
| RPS20 | ribosomal protein S20 | -0.0282085 |
| IGF2BP3 | insulin-like growth factor 2 mRNA binding protein 3 | -0.027894 |
| FER | fer (fps/fes related) tyrosine kinase | -0.0278539 |
| ANXA1 | annexin A1 | -0.0277003 |
| RPS29 | ribosomal protein S29 | -0.0276968 |
| PEG10 | paternally expressed 10 | -0.0276767 |
| NEBL | nebulette | -0.0275682 |
| MBD5 | methyl-CpG binding domain protein 5 | -0.027242 |
| JMJD1C | jumonji domain containing 1C | -0.026881 |
