| Dataset | Tahoe Therapeutics Tahoe 100M Perturbation Atlas |
| Category | transcriptomics |
| Type | cell type |
| Description | Erythromycin perturbation in CHP-212 cell line (Tahoe Therapeutics) |
| Similar Terms | |
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200 genes differentially expressed following the Erythromycin_CHP-212 drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| AKAP12 | A kinase (PRKA) anchor protein 12 | 0.144473 |
| VGF | VGF nerve growth factor inducible | 0.0626898 |
| VCL | vinculin | 0.0457743 |
| GOLGA4 | golgin A4 | 0.0445055 |
| HSP90AB1 | heat shock protein 90kDa alpha (cytosolic), class B member 1 | 0.0414256 |
| SEPTIN9 | septin 9 | 0.036291 |
| LPIN1 | lipin 1 | 0.0355304 |
| TIMP2 | TIMP metallopeptidase inhibitor 2 | 0.0337475 |
| BNIP3 | BCL2/adenovirus E1B 19kDa interacting protein 3 | 0.033462 |
| NFE2L1 | nuclear factor, erythroid 2-like 1 | 0.032547 |
| TIMP3 | TIMP metallopeptidase inhibitor 3 | 0.032376 |
| NCOR2 | nuclear receptor corepressor 2 | 0.0316852 |
| ANTXR1 | anthrax toxin receptor 1 | 0.0311167 |
| EGR1 | early growth response 1 | 0.0306469 |
| RPS2 | ribosomal protein S2 | 0.0296167 |
| RARA | retinoic acid receptor, alpha | 0.0284496 |
| PGAM4 | phosphoglycerate mutase family member 4 | 0.0271548 |
| SLC6A6 | solute carrier family 6 (neurotransmitter transporter), member 6 | 0.0270192 |
| RBM33 | RNA binding motif protein 33 | 0.026968 |
| PDE8A | phosphodiesterase 8A | 0.026553 |
| PRRC2C | proline-rich coiled-coil 2C | 0.0259252 |
| DHX40 | DEAH (Asp-Glu-Ala-His) box polypeptide 40 | 0.0251284 |
| HNRNPDL | heterogeneous nuclear ribonucleoprotein D-like | 0.024795 |
| HSPA8 | heat shock 70kDa protein 8 | 0.0246964 |
| SREBF2 | sterol regulatory element binding transcription factor 2 | 0.0246116 |
| PFKFB3 | 6-phosphofructo-2-kinase/fructose-2,6-biphosphatase 3 | 0.0244965 |
| AP3B1 | adaptor-related protein complex 3, beta 1 subunit | 0.0242 |
| PIBF1 | progesterone immunomodulatory binding factor 1 | 0.0241319 |
| RPS6 | ribosomal protein S6 | 0.0229602 |
| PCBP2 | poly(rC) binding protein 2 | 0.0226657 |
| PSME4 | proteasome (prosome, macropain) activator subunit 4 | 0.0225705 |
| HNRNPA1 | heterogeneous nuclear ribonucleoprotein A1 | 0.0222932 |
| EEF1A1 | eukaryotic translation elongation factor 1 alpha 1 | 0.0220062 |
| CTNND1 | catenin (cadherin-associated protein), delta 1 | 0.0219752 |
| BRD4 | bromodomain containing 4 | 0.0218972 |
| ZMIZ1 | zinc finger, MIZ-type containing 1 | 0.0218811 |
| PDGFRB | platelet-derived growth factor receptor, beta polypeptide | 0.0215964 |
| EIF4B | eukaryotic translation initiation factor 4B | 0.0215065 |
| BAZ2A | bromodomain adjacent to zinc finger domain, 2A | 0.0213653 |
| IGFBP4 | insulin-like growth factor binding protein 4 | 0.020803 |
| ANKS1A | ankyrin repeat and sterile alpha motif domain containing 1A | 0.0207665 |
| BRAF | B-Raf proto-oncogene, serine/threonine kinase | 0.0207174 |
| FAM13B | family with sequence similarity 13, member B | 0.0206871 |
| VIRMA | vir like m6A methyltransferase associated | 0.0206762 |
| PPP1R15A | protein phosphatase 1, regulatory subunit 15A | 0.0206075 |
| CTNNB1 | catenin (cadherin-associated protein), beta 1, 88kDa | 0.0204356 |
| RARS1 | arginyl-tRNA synthetase 1 | 0.020269 |
| PLAT | plasminogen activator, tissue | 0.0202682 |
| NAP1L1 | nucleosome assembly protein 1-like 1 | 0.0201144 |
| MIDEAS | mitotic deacetylase associated SANT domain protein | 0.0199614 |
| KDM5C | lysine (K)-specific demethylase 5C | 0.019879 |
| ARID4A | AT rich interactive domain 4A (RBP1-like) | 0.0198245 |
| MYCN | v-myc avian myelocytomatosis viral oncogene neuroblastoma derived homolog | 0.0197592 |
| SCARB1 | scavenger receptor class B, member 1 | 0.0196472 |
| MMP2 | matrix metallopeptidase 2 | 0.0193796 |
| CREB3L2 | cAMP responsive element binding protein 3-like 2 | 0.019215 |
| HDAC5 | histone deacetylase 5 | 0.0192039 |
| SRRM2 | serine/arginine repetitive matrix 2 | 0.0191495 |
| BCLAF1 | BCL2-associated transcription factor 1 | 0.0188124 |
| HMGB2 | high mobility group box 2 | 0.018692 |
| NPM1 | nucleophosmin (nucleolar phosphoprotein B23, numatrin) | 0.0182847 |
| MYO1E | myosin IE | 0.0182099 |
| BHLHE40 | basic helix-loop-helix family, member e40 | 0.0180923 |
| ASH1L | ash1 (absent, small, or homeotic)-like (Drosophila) | 0.0180689 |
| TPM3 | tropomyosin 3 | 0.0180532 |
| RPL4 | ribosomal protein L4 | 0.0180397 |
| ZNF146 | zinc finger protein 146 | 0.0179907 |
| FUT11 | fucosyltransferase 11 (alpha (1,3) fucosyltransferase) | 0.0179482 |
| MPRIP | myosin phosphatase Rho interacting protein | 0.0177966 |
| RPL5 | ribosomal protein L5 | 0.017604 |
| TRA2A | transformer 2 alpha homolog (Drosophila) | 0.0175353 |
| FAM219A | family with sequence similarity 219, member A | 0.0173727 |
| KDM3B | lysine (K)-specific demethylase 3B | 0.0173628 |
| TNRC6B | trinucleotide repeat containing 6B | 0.0172841 |
| EZR | ezrin | 0.0172248 |
| ATN1 | atrophin 1 | 0.0171476 |
| CD99 | CD99 molecule | 0.0169323 |
| TGFB1 | transforming growth factor, beta 1 | 0.016738 |
| MDK | midkine (neurite growth-promoting factor 2) | 0.0166689 |
| SSBP3 | single stranded DNA binding protein 3 | 0.0165537 |
| NFAT5 | nuclear factor of activated T-cells 5, tonicity-responsive | 0.0164773 |
| EXT1 | exostosin glycosyltransferase 1 | 0.0164737 |
| MBTD1 | mbt domain containing 1 | 0.016466 |
| TERF2IP | telomeric repeat binding factor 2, interacting protein | 0.0163706 |
| ZFP36 | ZFP36 ring finger protein | 0.0163453 |
| PRPF4B | pre-mRNA processing factor 4B | 0.0162749 |
| SFTPA2 | surfactant protein A2 | 0.0162455 |
| GOLPH3 | golgi phosphoprotein 3 (coat-protein) | 0.0162194 |
| TMF1 | TATA element modulatory factor 1 | 0.016152 |
| BNIP3L | BCL2/adenovirus E1B 19kDa interacting protein 3-like | 0.0159363 |
| CCNL1 | cyclin L1 | 0.0157796 |
| MAB21L2 | mab-21-like 2 (C. elegans) | 0.0157408 |
| BRD2 | bromodomain containing 2 | 0.0156933 |
| GOLGB1 | golgin B1 | 0.0151223 |
| CADM1 | cell adhesion molecule 1 | 0.0151105 |
| SBF2 | SET binding factor 2 | 0.015064 |
| SNX2 | sorting nexin 2 | 0.0149809 |
| TPI1 | triosephosphate isomerase 1 | 0.0149387 |
| UBA6 | ubiquitin-like modifier activating enzyme 6 | 0.0149097 |
| IGFBP5 | insulin-like growth factor binding protein 5 | 0.014862 |
| Symbol | Name | Standardized Value |
|---|---|---|
| DDX1 | DEAD (Asp-Glu-Ala-Asp) box helicase 1 | -0.48552 |
| SYT1 | synaptotagmin I | -0.124794 |
| PCDH9 | protocadherin 9 | -0.0803308 |
| RPS24 | ribosomal protein S24 | -0.0713929 |
| NALF1 | NALCN channel auxiliary factor 1 | -0.0705964 |
| RBMS3 | RNA binding motif, single stranded interacting protein 3 | -0.0652954 |
| SCN9A | sodium channel, voltage gated, type IX alpha subunit | -0.0630121 |
| RPL35A | ribosomal protein L35a | -0.0619597 |
| HSPA5 | heat shock 70kDa protein 5 (glucose-regulated protein, 78kDa) | -0.0618566 |
| MAP1B | microtubule-associated protein 1B | -0.0602478 |
| LSAMP | limbic system-associated membrane protein | -0.0576013 |
| RPLP1 | ribosomal protein, large, P1 | -0.0558903 |
| NAMPT | nicotinamide phosphoribosyltransferase | -0.0555572 |
| MEIS2 | Meis homeobox 2 | -0.0534539 |
| SOS1 | son of sevenless homolog 1 (Drosophila) | -0.0517395 |
| RPL19 | ribosomal protein L19 | -0.0511753 |
| RPL23 | ribosomal protein L23 | -0.0507683 |
| P4HB | prolyl 4-hydroxylase, beta polypeptide | -0.0506921 |
| ADGRG6 | adhesion G protein-coupled receptor G6 | -0.0504021 |
| FMN1 | formin 1 | -0.0495583 |
| HSP90B1 | heat shock protein 90kDa beta (Grp94), member 1 | -0.0481393 |
| VIM | vimentin | -0.0477211 |
| LRFN5 | leucine rich repeat and fibronectin type III domain containing 5 | -0.0445575 |
| RPL31 | ribosomal protein L31 | -0.0442012 |
| CD36 | CD36 molecule (thrombospondin receptor) | -0.0429331 |
| ZBTB20 | zinc finger and BTB domain containing 20 | -0.0420547 |
| RPLP0 | ribosomal protein, large, P0 | -0.0420181 |
| FAM13A | family with sequence similarity 13, member A | -0.0413209 |
| HNRNPA2B1 | heterogeneous nuclear ribonucleoprotein A2/B1 | -0.0411136 |
| HSP90AA1 | heat shock protein 90kDa alpha (cytosolic), class A member 1 | -0.0407999 |
| LINGO2 | leucine rich repeat and Ig domain containing 2 | -0.0404445 |
| RPL34 | ribosomal protein L34 | -0.0401951 |
| DTNA | dystrobrevin, alpha | -0.0399312 |
| RAD21 | RAD21 homolog (S. pombe) | -0.0397088 |
| HAND2 | heart and neural crest derivatives expressed 2 | -0.0388482 |
| CSDE1 | cold shock domain containing E1, RNA-binding | -0.0387888 |
| AHNAK | AHNAK nucleoprotein | -0.0387631 |
| BIRC6 | baculoviral IAP repeat containing 6 | -0.0385699 |
| PTPRD | protein tyrosine phosphatase, receptor type, D | -0.0379798 |
| CADM2 | cell adhesion molecule 2 | -0.037288 |
| UBR5 | ubiquitin protein ligase E3 component n-recognin 5 | -0.0371601 |
| FAM162A | family with sequence similarity 162, member A | -0.0364484 |
| IFI16 | interferon, gamma-inducible protein 16 | -0.0359058 |
| TPT1 | tumor protein, translationally-controlled 1 | -0.0350979 |
| TRIB2 | tribbles pseudokinase 2 | -0.034688 |
| PDIA3 | protein disulfide isomerase family A, member 3 | -0.034214 |
| ZNF804A | zinc finger protein 804A | -0.0338964 |
| HIF1A | hypoxia inducible factor 1, alpha subunit (basic helix-loop-helix transcription factor) | -0.0338853 |
| KLHL13 | kelch-like family member 13 | -0.0333087 |
| BPTF | bromodomain PHD finger transcription factor | -0.0332547 |
| SCD | stearoyl-CoA desaturase (delta-9-desaturase) | -0.0327292 |
| RPL38 | ribosomal protein L38 | -0.0322078 |
| CACNA2D1 | calcium channel, voltage-dependent, alpha 2/delta subunit 1 | -0.0321956 |
| RPS5 | ribosomal protein S5 | -0.0318104 |
| NF1 | neurofibromin 1 | -0.0315735 |
| MED13 | mediator complex subunit 13 | -0.0315533 |
| NCAM2 | neural cell adhesion molecule 2 | -0.03083 |
| CDH10 | cadherin 10, type 2 (T2-cadherin) | -0.0308021 |
| SLC25A36 | solute carrier family 25 (pyrimidine nucleotide carrier), member 36 | -0.0305245 |
| COL3A1 | collagen, type III, alpha 1 | -0.0304933 |
| XPR1 | xenotropic and polytropic retrovirus receptor 1 | -0.0303129 |
| DDX5 | DEAD (Asp-Glu-Ala-Asp) box helicase 5 | -0.02958 |
| TPST1 | tyrosylprotein sulfotransferase 1 | -0.0295586 |
| PLEKHA5 | pleckstrin homology domain containing, family A member 5 | -0.029147 |
| GPBP1 | GC-rich promoter binding protein 1 | -0.0289759 |
| ACTG1 | actin gamma 1 | -0.0280457 |
| ANKS1B | ankyrin repeat and sterile alpha motif domain containing 1B | -0.0278741 |
| RAP1B | RAP1B, member of RAS oncogene family | -0.0275278 |
| RPL27 | ribosomal protein L27 | -0.027305 |
| VPS13B | vacuolar protein sorting 13 homolog B (yeast) | -0.027295 |
| UNC5C | unc-5 homolog C (C. elegans) | -0.0266294 |
| WDR26 | WD repeat domain 26 | -0.0266265 |
| RPS11 | ribosomal protein S11 | -0.0257452 |
| VDAC1 | voltage-dependent anion channel 1 | -0.0253373 |
| ZNF609 | zinc finger protein 609 | -0.0253289 |
| NME2 | NME/NM23 nucleoside diphosphate kinase 2 | -0.0253059 |
| PTK2 | protein tyrosine kinase 2 | -0.0251459 |
| ROBO2 | roundabout, axon guidance receptor, homolog 2 (Drosophila) | -0.0251248 |
| LAMC1 | laminin, gamma 1 (formerly LAMB2) | -0.024923 |
| DNAH14 | dynein, axonemal, heavy chain 14 | -0.0248033 |
| C1ORF21 | chromosome 1 open reading frame 21 | -0.024768 |
| LUM | lumican | -0.024735 |
| ITPR2 | inositol 1,4,5-trisphosphate receptor, type 2 | -0.0243018 |
| WDR45B | WD repeat domain 45B | -0.0242418 |
| CACNB2 | calcium channel, voltage-dependent, beta 2 subunit | -0.0242407 |
| PRKDC | protein kinase, DNA-activated, catalytic polypeptide | -0.023853 |
| SENP6 | SUMO1/sentrin specific peptidase 6 | -0.0237294 |
| MDGA2 | MAM domain containing glycosylphosphatidylinositol anchor 2 | -0.0235571 |
| RPS8 | ribosomal protein S8 | -0.0235394 |
| EYA1 | EYA transcriptional coactivator and phosphatase 1 | -0.0233685 |
| HMBOX1 | homeobox containing 1 | -0.0233163 |
| GNA13 | guanine nucleotide binding protein (G protein), alpha 13 | -0.0232469 |
| SLC38A2 | solute carrier family 38, member 2 | -0.0230769 |
| NRG1 | neuregulin 1 | -0.0230393 |
| RBMX | RNA binding motif protein, X-linked | -0.0229968 |
| FNDC3B | fibronectin type III domain containing 3B | -0.0226245 |
| DST | dystonin | -0.0225676 |
| CCT6A | chaperonin containing TCP1, subunit 6A (zeta 1) | -0.0224965 |
| TAF1D | TATA box binding protein (TBP)-associated factor, RNA polymerase I, D, 41kDa | -0.0224073 |
| ERO1A | endoplasmic reticulum oxidoreductase 1 alpha | -0.0223768 |