| Dataset | Tahoe Therapeutics Tahoe 100M Perturbation Atlas |
| Category | transcriptomics |
| Type | cell type |
| Description | Erythromycin perturbation in KATO III cell line (Tahoe Therapeutics) |
| Similar Terms | |
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200 genes differentially expressed following the Erythromycin_KATO III drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| CEACAM5 | carcinoembryonic antigen-related cell adhesion molecule 5 | 0.0714725 |
| FTH1 | ferritin, heavy polypeptide 1 | 0.0572872 |
| RPS6 | ribosomal protein S6 | 0.0520843 |
| RPS2 | ribosomal protein S2 | 0.0382039 |
| ITGB4 | integrin, beta 4 | 0.0345099 |
| MAML2 | mastermind-like 2 (Drosophila) | 0.0341226 |
| TPI1 | triosephosphate isomerase 1 | 0.0315377 |
| NFE2L1 | nuclear factor, erythroid 2-like 1 | 0.0282347 |
| NCOR2 | nuclear receptor corepressor 2 | 0.0273954 |
| SRRM2 | serine/arginine repetitive matrix 2 | 0.025817 |
| BCL2L1 | BCL2-like 1 | 0.0242278 |
| PCBP2 | poly(rC) binding protein 2 | 0.0229816 |
| TTYH3 | tweety family member 3 | 0.0220373 |
| WWC1 | WW and C2 domain containing 1 | 0.0213537 |
| CEACAM1 | carcinoembryonic antigen-related cell adhesion molecule 1 (biliary glycoprotein) | 0.0202378 |
| RPL21 | ribosomal protein L21 | 0.0198378 |
| TPM3 | tropomyosin 3 | 0.0197665 |
| PGAM4 | phosphoglycerate mutase family member 4 | 0.0188105 |
| MUC1 | mucin 1, cell surface associated | 0.0184108 |
| RPS12 | ribosomal protein S12 | 0.0176268 |
| VEGFA | vascular endothelial growth factor A | 0.0174294 |
| LAMA5 | laminin, alpha 5 | 0.0173131 |
| DHX40 | DEAH (Asp-Glu-Ala-His) box polypeptide 40 | 0.0172112 |
| PNN | pinin, desmosome associated protein | 0.0168904 |
| BAZ2A | bromodomain adjacent to zinc finger domain, 2A | 0.0155266 |
| GBE1 | glucan (1,4-alpha-), branching enzyme 1 | 0.0154283 |
| BCL9L | B-cell CLL/lymphoma 9-like | 0.0152926 |
| CAPN5 | calpain 5 | 0.0152868 |
| MT2A | metallothionein 2A | 0.0152534 |
| AKAP12 | A kinase (PRKA) anchor protein 12 | 0.0150013 |
| LSR | lipolysis stimulated lipoprotein receptor | 0.0149196 |
| C6ORF132 | chromosome 6 open reading frame 132 | 0.0147443 |
| EGR1 | early growth response 1 | 0.0143635 |
| SLC7A5 | solute carrier family 7 (amino acid transporter light chain, L system), member 5 | 0.0139976 |
| PHLDA1 | pleckstrin homology-like domain, family A, member 1 | 0.0139118 |
| SF3A1 | splicing factor 3a, subunit 1, 120kDa | 0.0138353 |
| TMA7 | translation machinery associated 7 homolog (S. cerevisiae) | 0.0134714 |
| VIM | vimentin | 0.0134015 |
| CYP3A5 | cytochrome P450, family 3, subfamily A, polypeptide 5 | 0.0133419 |
| BRD4 | bromodomain containing 4 | 0.0129933 |
| FN1 | fibronectin 1 | 0.0129555 |
| SRRM1 | serine/arginine repetitive matrix 1 | 0.0129045 |
| CCNL1 | cyclin L1 | 0.0126982 |
| TNRC18 | trinucleotide repeat containing 18 | 0.0121859 |
| EEF1A1 | eukaryotic translation elongation factor 1 alpha 1 | 0.0121766 |
| RPL4 | ribosomal protein L4 | 0.0121554 |
| MINK1 | misshapen-like kinase 1 | 0.0121449 |
| SHB | Src homology 2 domain containing adaptor protein B | 0.0119756 |
| UBE2C | ubiquitin-conjugating enzyme E2C | 0.0118704 |
| DCAF7 | DDB1 and CUL4 associated factor 7 | 0.0117243 |
| DHFR | dihydrofolate reductase | 0.0113319 |
| CNOT3 | CCR4-NOT transcription complex, subunit 3 | 0.0112208 |
| KMT2D | lysine (K)-specific methyltransferase 2D | 0.0110607 |
| HDGF | hepatoma-derived growth factor | 0.0109774 |
| PHC3 | polyhomeotic homolog 3 (Drosophila) | 0.0108918 |
| PPP1R15A | protein phosphatase 1, regulatory subunit 15A | 0.0108355 |
| UBA6 | ubiquitin-like modifier activating enzyme 6 | 0.010817 |
| SERPINE1 | serpin peptidase inhibitor, clade E (nexin, plasminogen activator inhibitor type 1), member 1 | 0.0107395 |
| SEPTIN9 | septin 9 | 0.0106167 |
| SMYD3 | SET and MYND domain containing 3 | 0.010584 |
| TM9SF4 | transmembrane 9 superfamily protein member 4 | 0.0105355 |
| TNS4 | tensin 4 | 0.010531 |
| RPS7 | ribosomal protein S7 | 0.0105292 |
| SLC6A8 | solute carrier family 6 (neurotransmitter transporter), member 8 | 0.0103882 |
| SREBF1 | sterol regulatory element binding transcription factor 1 | 0.0103424 |
| TUBA1B | tubulin, alpha 1b | 0.010335 |
| BCL3 | B-cell CLL/lymphoma 3 | 0.0101485 |
| PDAP1 | PDGFA associated protein 1 | 0.0100604 |
| EIF5B | eukaryotic translation initiation factor 5B | 0.00967872 |
| MMP24OS | MMP24 opposite strand | 0.00967801 |
| PDE10A | phosphodiesterase 10A | 0.0096133 |
| EIF4G1 | eukaryotic translation initiation factor 4 gamma, 1 | 0.00952368 |
| NUCKS1 | nuclear casein kinase and cyclin-dependent kinase substrate 1 | 0.00950381 |
| FOSL2 | FOS-like antigen 2 | 0.00946958 |
| PRPF4B | pre-mRNA processing factor 4B | 0.00943316 |
| HMGN2 | high mobility group nucleosomal binding domain 2 | 0.00937335 |
| ASPH | aspartate beta-hydroxylase | 0.00932004 |
| PITPNC1 | phosphatidylinositol transfer protein, cytoplasmic 1 | 0.00931523 |
| PRRC2A | proline-rich coiled-coil 2A | 0.00920958 |
| ITGA3 | integrin, alpha 3 (antigen CD49C, alpha 3 subunit of VLA-3 receptor) | 0.00904498 |
| GPC6 | glypican 6 | 0.00898863 |
| SSRP1 | structure specific recognition protein 1 | 0.00897887 |
| FLNA | filamin A, alpha | 0.00897221 |
| NAP1L1 | nucleosome assembly protein 1-like 1 | 0.00892134 |
| SLC9A3R1 | solute carrier family 9, subfamily A (NHE3, cation proton antiporter 3), member 3 regulator 1 | 0.00889368 |
| SEC16A | SEC16 homolog A (S. cerevisiae) | 0.00888452 |
| TLN1 | talin 1 | 0.00879548 |
| MKI67 | marker of proliferation Ki-67 | 0.00876141 |
| GAK | cyclin G associated kinase | 0.00874919 |
| DST | dystonin | 0.00874427 |
| PABPN1 | poly(A) binding protein, nuclear 1 | 0.00873128 |
| ANKZF1 | ankyrin repeat and zinc finger domain containing 1 | 0.0086614 |
| LENG8 | leukocyte receptor cluster (LRC) member 8 | 0.00863263 |
| PFKFB3 | 6-phosphofructo-2-kinase/fructose-2,6-biphosphatase 3 | 0.00844089 |
| EEF1G | eukaryotic translation elongation factor 1 gamma | 0.00838033 |
| CDC42BPB | CDC42 binding protein kinase beta (DMPK-like) | 0.00837474 |
| DLGAP4 | discs, large (Drosophila) homolog-associated protein 4 | 0.00834509 |
| KDM6B | lysine (K)-specific demethylase 6B | 0.00831923 |
| RNF24 | ring finger protein 24 | 0.00831183 |
| KDM5C | lysine (K)-specific demethylase 5C | 0.00830135 |
| Symbol | Name | Standardized Value |
|---|---|---|
| HSPA5 | heat shock 70kDa protein 5 (glucose-regulated protein, 78kDa) | -0.336196 |
| HSP90B1 | heat shock protein 90kDa beta (Grp94), member 1 | -0.214976 |
| LMO7 | LIM domain 7 | -0.141088 |
| EMP1 | epithelial membrane protein 1 | -0.131129 |
| ANXA2 | annexin A2 | -0.123599 |
| AGR2 | anterior gradient 2 | -0.121011 |
| PDIA3 | protein disulfide isomerase family A, member 3 | -0.101361 |
| GFPT1 | glutamine--fructose-6-phosphate transaminase 1 | -0.100352 |
| FGFR2 | fibroblast growth factor receptor 2 | -0.0881814 |
| TPT1 | tumor protein, translationally-controlled 1 | -0.0867592 |
| PGK1 | phosphoglycerate kinase 1 | -0.0816208 |
| TMSB10 | thymosin beta 10 | -0.0780965 |
| SLC7A11 | solute carrier family 7 (anionic amino acid transporter light chain, xc- system), member 11 | -0.0748397 |
| CTNNB1 | catenin (cadherin-associated protein), beta 1, 88kDa | -0.0734093 |
| HNRNPA2B1 | heterogeneous nuclear ribonucleoprotein A2/B1 | -0.0668902 |
| SPTBN1 | spectrin, beta, non-erythrocytic 1 | -0.0667371 |
| KRT18 | keratin 18, type I | -0.0647281 |
| IARS1 | isoleucyl-tRNA synthetase 1 | -0.0643641 |
| GMDS | GDP-mannose 4,6-dehydratase | -0.0639744 |
| AHNAK | AHNAK nucleoprotein | -0.0632144 |
| CD2AP | CD2-associated protein | -0.0599179 |
| RAB1A | RAB1A, member RAS oncogene family | -0.0589595 |
| CANX | calnexin | -0.0577965 |
| EPCAM | epithelial cell adhesion molecule | -0.057374 |
| POTEF | POTE ankyrin domain family, member F | -0.0562798 |
| TMEM123 | transmembrane protein 123 | -0.0556955 |
| ANXA1 | annexin A1 | -0.0553228 |
| CEMIP | cell migration inducing protein, hyaluronan binding | -0.0551774 |
| EZR | ezrin | -0.0546215 |
| EIF1 | eukaryotic translation initiation factor 1 | -0.0544504 |
| NDRG1 | N-myc downstream regulated 1 | -0.0532706 |
| ARL6IP1 | ADP-ribosylation factor-like 6 interacting protein 1 | -0.0532123 |
| COPB2 | coatomer protein complex, subunit beta 2 (beta prime) | -0.0529721 |
| ASNS | asparagine synthetase (glutamine-hydrolyzing) | -0.0529709 |
| MORF4L2 | mortality factor 4 like 2 | -0.0524831 |
| WDR45B | WD repeat domain 45B | -0.0517092 |
| MBNL2 | muscleblind-like splicing regulator 2 | -0.05163 |
| KDM3A | lysine (K)-specific demethylase 3A | -0.0514254 |
| S100A10 | S100 calcium binding protein A10 | -0.0513276 |
| B2M | beta-2-microglobulin | -0.0505087 |
| SCD | stearoyl-CoA desaturase (delta-9-desaturase) | -0.0504529 |
| AHR | aryl hydrocarbon receptor | -0.0485375 |
| TMSB4X | thymosin beta 4, X-linked | -0.0482289 |
| RRBP1 | ribosome binding protein 1 | -0.0479543 |
| RPL35A | ribosomal protein L35a | -0.0472668 |
| RAD21 | RAD21 homolog (S. pombe) | -0.047136 |
| SLC38A1 | solute carrier family 38, member 1 | -0.047131 |
| FNDC3B | fibronectin type III domain containing 3B | -0.0470948 |
| LOC112694756 | uncharaterized LOC112694756 | -0.047075 |
| TES | testin LIM domain protein | -0.0470379 |
| HLA-E | major histocompatibility complex, class I, E | -0.046131 |
| CALR | calreticulin | -0.0460313 |
| PTPRK | protein tyrosine phosphatase, receptor type, K | -0.0460034 |
| ACTN4 | actinin, alpha 4 | -0.0458181 |
| SEC31A | SEC31 homolog A (S. cerevisiae) | -0.0455216 |
| RPL23 | ribosomal protein L23 | -0.0453991 |
| P4HB | prolyl 4-hydroxylase, beta polypeptide | -0.0442566 |
| S100A6 | S100 calcium binding protein A6 | -0.0436188 |
| ACTG1 | actin gamma 1 | -0.0433146 |
| SLC25A36 | solute carrier family 25 (pyrimidine nucleotide carrier), member 36 | -0.0430536 |
| YWHAZ | tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, zeta | -0.0426488 |
| PDIA4 | protein disulfide isomerase family A, member 4 | -0.0422772 |
| KRT8 | keratin 8, type II | -0.0422098 |
| TAX1BP1 | Tax1 (human T-cell leukemia virus type I) binding protein 1 | -0.0415 |
| RAB2A | RAB2A, member RAS oncogene family | -0.0410651 |
| GAPDH | glyceraldehyde-3-phosphate dehydrogenase | -0.0408933 |
| AKAP13 | A kinase (PRKA) anchor protein 13 | -0.0408681 |
| CTNNA1 | catenin (cadherin-associated protein), alpha 1, 102kDa | -0.040613 |
| TXNRD1 | thioredoxin reductase 1 | -0.0403062 |
| KRT19 | keratin 19, type I | -0.0398494 |
| ZCCHC7 | zinc finger, CCHC domain containing 7 | -0.0397624 |
| RPLP1 | ribosomal protein, large, P1 | -0.0396419 |
| RPS24 | ribosomal protein S24 | -0.0391088 |
| KLF5 | Kruppel-like factor 5 (intestinal) | -0.0378661 |
| HLA-C | major histocompatibility complex, class I, C | -0.0374539 |
| DDX5 | DEAD (Asp-Glu-Ala-Asp) box helicase 5 | -0.0373019 |
| RNF213 | ring finger protein 213 | -0.0370295 |
| EPS8 | epidermal growth factor receptor pathway substrate 8 | -0.0364428 |
| ARHGAP32 | Rho GTPase activating protein 32 | -0.0360973 |
| MYOF | myoferlin | -0.0356059 |
| HSD17B12 | hydroxysteroid (17-beta) dehydrogenase 12 | -0.0355553 |
| ERO1A | endoplasmic reticulum oxidoreductase 1 alpha | -0.0355089 |
| FTL | ferritin, light polypeptide | -0.0352838 |
| GARS1 | glycyl-tRNA synthetase 1 | -0.0350856 |
| LMAN1 | lectin, mannose-binding, 1 | -0.0350657 |
| SNX9 | sorting nexin 9 | -0.0349073 |
| ATXN1 | ataxin 1 | -0.0348309 |
| HSPD1 | heat shock 60kDa protein 1 (chaperonin) | -0.0347586 |
| HLA-A | major histocompatibility complex, class I, A | -0.0342921 |
| SPDYA | speedy/RINGO cell cycle regulator family member A | -0.0337312 |
| LYZ | lysozyme | -0.0332992 |
| TOP1 | topoisomerase (DNA) I | -0.033199 |
| RPS25 | ribosomal protein S25 | -0.0331074 |
| ZFAND3 | zinc finger, AN1-type domain 3 | -0.0330795 |
| IQGAP1 | IQ motif containing GTPase activating protein 1 | -0.0330715 |
| EXT1 | exostosin glycosyltransferase 1 | -0.0327135 |
| RPLP0 | ribosomal protein, large, P0 | -0.0327064 |
| LPP | LIM domain containing preferred translocation partner in lipoma | -0.0326869 |
| TBL1XR1 | transducin (beta)-like 1 X-linked receptor 1 | -0.0324775 |
| KLHL29 | kelch-like family member 29 | -0.0317309 |
