| Dataset | Tahoe Therapeutics Tahoe 100M Perturbation Atlas |
| Category | transcriptomics |
| Type | cell type |
| Description | Erythromycin perturbation in NCI-H1792 cell line (Tahoe Therapeutics) |
| Similar Terms | |
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200 genes differentially expressed following the Erythromycin_NCI-H1792 drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| FTH1 | ferritin, heavy polypeptide 1 | 0.0615436 |
| HSP90AB1 | heat shock protein 90kDa alpha (cytosolic), class B member 1 | 0.0498254 |
| GOLGA4 | golgin A4 | 0.0449871 |
| PCBP2 | poly(rC) binding protein 2 | 0.0430134 |
| RPS2 | ribosomal protein S2 | 0.0345728 |
| BHLHE40 | basic helix-loop-helix family, member e40 | 0.0320633 |
| WAC | WW domain containing adaptor with coiled-coil | 0.0215827 |
| RNF145 | ring finger protein 145 | 0.0204354 |
| UBA6 | ubiquitin-like modifier activating enzyme 6 | 0.0204181 |
| EIF4H | eukaryotic translation initiation factor 4H | 0.0193254 |
| ATP13A3 | ATPase type 13A3 | 0.0191258 |
| RIOK3 | RIO kinase 3 | 0.0190566 |
| RPL4 | ribosomal protein L4 | 0.0181398 |
| RPS6 | ribosomal protein S6 | 0.0178041 |
| FAM13A | family with sequence similarity 13, member A | 0.0176988 |
| NPM1 | nucleophosmin (nucleolar phosphoprotein B23, numatrin) | 0.0171507 |
| USP3 | ubiquitin specific peptidase 3 | 0.0171432 |
| EEF1A1 | eukaryotic translation elongation factor 1 alpha 1 | 0.0169787 |
| HILPDA | hypoxia inducible lipid droplet-associated | 0.0167808 |
| PPP2R2A | protein phosphatase 2, regulatory subunit B, alpha | 0.0166494 |
| YBX1 | Y box binding protein 1 | 0.0161492 |
| PPP1R15A | protein phosphatase 1, regulatory subunit 15A | 0.0159717 |
| HELZ | helicase with zinc finger | 0.0156919 |
| PABPC1 | poly(A) binding protein, cytoplasmic 1 | 0.0155704 |
| SPAG9 | sperm associated antigen 9 | 0.0151779 |
| TRA2A | transformer 2 alpha homolog (Drosophila) | 0.0150742 |
| CHD1 | chromodomain helicase DNA binding protein 1 | 0.0146197 |
| PNN | pinin, desmosome associated protein | 0.0142898 |
| AP3S1 | adaptor-related protein complex 3, sigma 1 subunit | 0.0139735 |
| RBM39 | RNA binding motif protein 39 | 0.0138702 |
| PGAM4 | phosphoglycerate mutase family member 4 | 0.0137426 |
| SETD5 | SET domain containing 5 | 0.0135555 |
| ARL8B | ADP-ribosylation factor-like 8B | 0.013463 |
| NUP58 | nucleoporin 58 | 0.013383 |
| BCLAF1 | BCL2-associated transcription factor 1 | 0.0128868 |
| HNRNPDL | heterogeneous nuclear ribonucleoprotein D-like | 0.0128091 |
| PIK3C2A | phosphatidylinositol-4-phosphate 3-kinase, catalytic subunit type 2 alpha | 0.0125837 |
| ESYT2 | extended synaptotagmin-like protein 2 | 0.0123163 |
| DYRK1A | dual-specificity tyrosine-(Y)-phosphorylation regulated kinase 1A | 0.0122779 |
| FXR1 | fragile X mental retardation, autosomal homolog 1 | 0.0122554 |
| SUCO | SUN domain containing ossification factor | 0.012157 |
| RSRC2 | arginine/serine-rich coiled-coil 2 | 0.0119242 |
| DHX40 | DEAH (Asp-Glu-Ala-His) box polypeptide 40 | 0.0118633 |
| WDR43 | WD repeat domain 43 | 0.0118061 |
| PPP2R5E | protein phosphatase 2, regulatory subunit B', epsilon isoform | 0.0115213 |
| BAZ2A | bromodomain adjacent to zinc finger domain, 2A | 0.0115083 |
| QKI | QKI, KH domain containing, RNA binding | 0.0113651 |
| LRRFIP2 | leucine rich repeat (in FLII) interacting protein 2 | 0.0113113 |
| SRP54 | signal recognition particle 54kDa | 0.011131 |
| SET | SET nuclear proto-oncogene | 0.0111257 |
| XPO1 | exportin 1 | 0.0108349 |
| DHX15 | DEAH (Asp-Glu-Ala-His) box helicase 15 | 0.010702 |
| HMGB2 | high mobility group box 2 | 0.0106573 |
| HSPA8 | heat shock 70kDa protein 8 | 0.0105789 |
| RAB8B | RAB8B, member RAS oncogene family | 0.010493 |
| HSPD1 | heat shock 60kDa protein 1 (chaperonin) | 0.0102286 |
| PSMD14 | proteasome (prosome, macropain) 26S subunit, non-ATPase, 14 | 0.0101977 |
| NFE2L1 | nuclear factor, erythroid 2-like 1 | 0.0100336 |
| LUC7L3 | LUC7-like 3 (S. cerevisiae) | 0.01003 |
| BNIP3 | BCL2/adenovirus E1B 19kDa interacting protein 3 | 0.00988596 |
| ARID4B | AT rich interactive domain 4B (RBP1-like) | 0.00980195 |
| HNRNPA1 | heterogeneous nuclear ribonucleoprotein A1 | 0.00967063 |
| PRRC2C | proline-rich coiled-coil 2C | 0.00963647 |
| WBP11 | WW domain binding protein 11 | 0.00941394 |
| PAPOLA | poly(A) polymerase alpha | 0.00940577 |
| ITCH | itchy E3 ubiquitin protein ligase | 0.00930167 |
| FOSB | FBJ murine osteosarcoma viral oncogene homolog B | 0.00923042 |
| MARCHF6 | membrane associated ring-CH-type finger 6 | 0.00923001 |
| YTHDC1 | YTH domain containing 1 | 0.00921661 |
| NOP58 | NOP58 ribonucleoprotein | 0.00919142 |
| NAP1L1 | nucleosome assembly protein 1-like 1 | 0.00907964 |
| FBXO42 | F-box protein 42 | 0.00903886 |
| EEF2 | eukaryotic translation elongation factor 2 | 0.00901707 |
| MIDEAS | mitotic deacetylase associated SANT domain protein | 0.008979 |
| EIF3A | eukaryotic translation initiation factor 3, subunit A | 0.00891861 |
| NCKAP1 | NCK-associated protein 1 | 0.00890886 |
| YWHAG | tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, gamma | 0.00885259 |
| DNAJC5 | DnaJ (Hsp40) homolog, subfamily C, member 5 | 0.00883624 |
| TCERG1 | transcription elongation regulator 1 | 0.00881634 |
| MIER1 | mesoderm induction early response 1, transcriptional regulator | 0.00880163 |
| STRN3 | striatin, calmodulin binding protein 3 | 0.00867911 |
| HDAC3 | histone deacetylase 3 | 0.00848195 |
| RPL3 | ribosomal protein L3 | 0.00841518 |
| TOP2A | topoisomerase (DNA) II alpha 170kDa | 0.00823512 |
| EIF3B | eukaryotic translation initiation factor 3, subunit B | 0.00818513 |
| LCORL | ligand dependent nuclear receptor corepressor-like | 0.00816923 |
| PTBP2 | polypyrimidine tract binding protein 2 | 0.00814698 |
| HSPA9 | heat shock 70kDa protein 9 (mortalin) | 0.00814499 |
| GARS1 | glycyl-tRNA synthetase 1 | 0.0081313 |
| BNIP3L | BCL2/adenovirus E1B 19kDa interacting protein 3-like | 0.00810808 |
| SRRM1 | serine/arginine repetitive matrix 1 | 0.00808047 |
| PRPF4B | pre-mRNA processing factor 4B | 0.00807006 |
| FHIP1A | FHF complex subunit HOOK interacting protein 1A | 0.00806683 |
| HNRNPC | heterogeneous nuclear ribonucleoprotein C (C1/C2) | 0.00789909 |
| TMEM41B | transmembrane protein 41B | 0.00783732 |
| CENPF | centromere protein F, 350/400kDa | 0.00783605 |
| SSRP1 | structure specific recognition protein 1 | 0.0078065 |
| MLLT10 | myeloid/lymphoid or mixed-lineage leukemia (trithorax homolog, Drosophila); translocated to, 10 | 0.00776027 |
| ARIH1 | ariadne RBR E3 ubiquitin protein ligase 1 | 0.00775607 |
| ELP2 | elongator acetyltransferase complex subunit 2 | 0.00775443 |
| Symbol | Name | Standardized Value |
|---|---|---|
| PDE4D | phosphodiesterase 4D, cAMP-specific | -0.161714 |
| EFNA5 | ephrin-A5 | -0.0982719 |
| SDK1 | sidekick cell adhesion molecule 1 | -0.0937026 |
| VIM | vimentin | -0.0885514 |
| TMSB10 | thymosin beta 10 | -0.0880375 |
| CD44 | CD44 molecule (Indian blood group) | -0.0873504 |
| MT2A | metallothionein 2A | -0.0847816 |
| CXCL8 | chemokine (C-X-C motif) ligand 8 | -0.0766939 |
| PITPNC1 | phosphatidylinositol transfer protein, cytoplasmic 1 | -0.0624723 |
| MAGI2 | membrane associated guanylate kinase, WW and PDZ domain containing 2 | -0.0605955 |
| USP34 | ubiquitin specific peptidase 34 | -0.0601572 |
| FNDC3B | fibronectin type III domain containing 3B | -0.0595118 |
| SIPA1L1 | signal-induced proliferation-associated 1 like 1 | -0.0593026 |
| NAMPT | nicotinamide phosphoribosyltransferase | -0.0585433 |
| AGAP1 | ArfGAP with GTPase domain, ankyrin repeat and PH domain 1 | -0.0565717 |
| RBMS3 | RNA binding motif, single stranded interacting protein 3 | -0.055923 |
| CAMK1D | calcium/calmodulin-dependent protein kinase ID | -0.0559176 |
| GAPDH | glyceraldehyde-3-phosphate dehydrogenase | -0.0548439 |
| CDH13 | cadherin 13 | -0.0533033 |
| HIF1A | hypoxia inducible factor 1, alpha subunit (basic helix-loop-helix transcription factor) | -0.0525704 |
| GPRC5A | G protein-coupled receptor, class C, group 5, member A | -0.050908 |
| HMGA2 | high mobility group AT-hook 2 | -0.0502207 |
| FAM20C | family with sequence similarity 20, member C | -0.0499715 |
| ITGA2 | integrin, alpha 2 (CD49B, alpha 2 subunit of VLA-2 receptor) | -0.0489405 |
| RPLP1 | ribosomal protein, large, P1 | -0.0484484 |
| FN1 | fibronectin 1 | -0.0479136 |
| IMMP2L | IMP2 inner mitochondrial membrane peptidase-like (S. cerevisiae) | -0.0477032 |
| DPYD | dihydropyrimidine dehydrogenase | -0.0459888 |
| GPC6 | glypican 6 | -0.0450284 |
| NCOA7 | nuclear receptor coactivator 7 | -0.0449748 |
| NHS | Nance-Horan syndrome (congenital cataracts and dental anomalies) | -0.0448369 |
| NRG1 | neuregulin 1 | -0.0441941 |
| OSMR | oncostatin M receptor | -0.0436427 |
| HSP90B1 | heat shock protein 90kDa beta (Grp94), member 1 | -0.0424792 |
| ANTXR2 | anthrax toxin receptor 2 | -0.0417821 |
| APBB2 | amyloid beta (A4) precursor protein-binding, family B, member 2 | -0.0403764 |
| ATXN1 | ataxin 1 | -0.0402381 |
| NRP1 | neuropilin 1 | -0.0400374 |
| PRELID2 | PRELI domain containing 2 | -0.0397426 |
| NDRG1 | N-myc downstream regulated 1 | -0.0392101 |
| SOD2 | superoxide dismutase 2, mitochondrial | -0.0389939 |
| ZBTB20 | zinc finger and BTB domain containing 20 | -0.0373698 |
| AKAP12 | A kinase (PRKA) anchor protein 12 | -0.0368068 |
| EXT1 | exostosin glycosyltransferase 1 | -0.0355797 |
| ARHGAP5 | Rho GTPase activating protein 5 | -0.0354993 |
| CDCP1 | CUB domain containing protein 1 | -0.0349933 |
| LRMDA | leucine rich melanocyte differentiation associated | -0.0342956 |
| NAV2 | neuron navigator 2 | -0.0339418 |
| EDIL3 | EGF-like repeats and discoidin I-like domains 3 | -0.0338676 |
| PARP14 | poly (ADP-ribose) polymerase family, member 14 | -0.033719 |
| RPL35A | ribosomal protein L35a | -0.0333261 |
| RAD51B | RAD51 paralog B | -0.0332968 |
| ETV6 | ets variant 6 | -0.0330685 |
| AKAP13 | A kinase (PRKA) anchor protein 13 | -0.0327542 |
| GLCCI1 | glucocorticoid induced 1 | -0.0325572 |
| ITPR1 | inositol 1,4,5-trisphosphate receptor, type 1 | -0.0325363 |
| GRB10 | growth factor receptor-bound protein 10 | -0.0307353 |
| PLOD2 | procollagen-lysine, 2-oxoglutarate 5-dioxygenase 2 | -0.0306418 |
| CD55 | CD55 molecule, decay accelerating factor for complement (Cromer blood group) | -0.0305986 |
| RPS24 | ribosomal protein S24 | -0.0302765 |
| PSD3 | pleckstrin and Sec7 domain containing 3 | -0.0301847 |
| ABCA1 | ATP-binding cassette, sub-family A (ABC1), member 1 | -0.0300147 |
| STAT1 | signal transducer and activator of transcription 1, 91kDa | -0.0299697 |
| MAP4K4 | mitogen-activated protein kinase kinase kinase kinase 4 | -0.0299684 |
| SMAD3 | SMAD family member 3 | -0.029743 |
| NPC1 | Niemann-Pick disease, type C1 | -0.0292223 |
| MSRB3 | methionine sulfoxide reductase B3 | -0.0290656 |
| PTPN12 | protein tyrosine phosphatase, non-receptor type 12 | -0.0286984 |
| SRGAP1 | SLIT-ROBO Rho GTPase activating protein 1 | -0.0286704 |
| MAML3 | mastermind-like 3 (Drosophila) | -0.0285321 |
| GBE1 | glucan (1,4-alpha-), branching enzyme 1 | -0.0283318 |
| TFPI | tissue factor pathway inhibitor (lipoprotein-associated coagulation inhibitor) | -0.0272196 |
| TFPI2 | tissue factor pathway inhibitor 2 | -0.0267023 |
| C15ORF48 | chromosome 15 open reading frame 48 | -0.0265378 |
| MAML2 | mastermind-like 2 (Drosophila) | -0.0265304 |
| TANC2 | tetratricopeptide repeat, ankyrin repeat and coiled-coil containing 2 | -0.026435 |
| EGFR | epidermal growth factor receptor | -0.0257529 |
| SAMD9 | sterile alpha motif domain containing 9 | -0.0254242 |
| AHNAK | AHNAK nucleoprotein | -0.025274 |
| RAP1B | RAP1B, member of RAS oncogene family | -0.0252351 |
| LPP | LIM domain containing preferred translocation partner in lipoma | -0.0250819 |
| SERPINE1 | serpin peptidase inhibitor, clade E (nexin, plasminogen activator inhibitor type 1), member 1 | -0.0250419 |
| STC1 | stanniocalcin 1 | -0.0245507 |
| RNF213 | ring finger protein 213 | -0.0244158 |
| IFI16 | interferon, gamma-inducible protein 16 | -0.0243221 |
| DOCK5 | dedicator of cytokinesis 5 | -0.0241776 |
| B2M | beta-2-microglobulin | -0.0240786 |
| PRKCA | protein kinase C, alpha | -0.0237565 |
| RERE | arginine-glutamic acid dipeptide (RE) repeats | -0.0236999 |
| TRIO | trio Rho guanine nucleotide exchange factor | -0.0235381 |
| ZMYND8 | zinc finger, MYND-type containing 8 | -0.0233834 |
| ITGB1 | integrin, beta 1 (fibronectin receptor, beta polypeptide, antigen CD29 includes MDF2, MSK12) | -0.0230995 |
| INPP4B | inositol polyphosphate-4-phosphatase, type II, 105kDa | -0.0229851 |
| LDHA | lactate dehydrogenase A | -0.0229598 |
| LMAN1 | lectin, mannose-binding, 1 | -0.022834 |
| ANGPTL4 | angiopoietin-like 4 | -0.0228162 |
| PPFIBP1 | PTPRF interacting protein, binding protein 1 (liprin beta 1) | -0.0226057 |
| MACF1 | microtubule-actin crosslinking factor 1 | -0.0224085 |
| HLA-B | major histocompatibility complex, class I, B | -0.0223241 |
| RPL23 | ribosomal protein L23 | -0.0222426 |
