| Dataset | Tahoe Therapeutics Tahoe 100M Perturbation Atlas |
| Category | transcriptomics |
| Type | cell type |
| Description | Erythromycin perturbation in NCI-H23 cell line (Tahoe Therapeutics) |
| Similar Terms | |
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200 genes differentially expressed following the Erythromycin_NCI-H23 drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| EEF1A1 | eukaryotic translation elongation factor 1 alpha 1 | 0.0759435 |
| EGR1 | early growth response 1 | 0.0752816 |
| ERRFI1 | ERBB receptor feedback inhibitor 1 | 0.0713887 |
| EEF2 | eukaryotic translation elongation factor 2 | 0.0554454 |
| TLN1 | talin 1 | 0.0437135 |
| GOLGA4 | golgin A4 | 0.0352773 |
| RPS2 | ribosomal protein S2 | 0.0331434 |
| COPA | coatomer protein complex, subunit alpha | 0.0322675 |
| ETS1 | v-ets avian erythroblastosis virus E26 oncogene homolog 1 | 0.0318434 |
| NPM1 | nucleophosmin (nucleolar phosphoprotein B23, numatrin) | 0.0318222 |
| TRIO | trio Rho guanine nucleotide exchange factor | 0.0309386 |
| HSPA8 | heat shock 70kDa protein 8 | 0.0307897 |
| WNK1 | WNK lysine deficient protein kinase 1 | 0.0300861 |
| BAZ2A | bromodomain adjacent to zinc finger domain, 2A | 0.0298783 |
| KDM3A | lysine (K)-specific demethylase 3A | 0.0286263 |
| PER1 | period circadian clock 1 | 0.0266164 |
| RPL4 | ribosomal protein L4 | 0.0248243 |
| ANO6 | anoctamin 6 | 0.0241073 |
| NR4A1 | nuclear receptor subfamily 4, group A, member 1 | 0.0238819 |
| HERC4 | HECT and RLD domain containing E3 ubiquitin protein ligase 4 | 0.0237169 |
| FLNA | filamin A, alpha | 0.0223038 |
| ELL2 | elongation factor, RNA polymerase II, 2 | 0.0221339 |
| PRPF4B | pre-mRNA processing factor 4B | 0.0205491 |
| EIF4B | eukaryotic translation initiation factor 4B | 0.0204316 |
| ARID1A | AT rich interactive domain 1A (SWI-like) | 0.020354 |
| GOLT1B | golgi transport 1B | 0.0201991 |
| ALG13 | ALG13, UDP-N-acetylglucosaminyltransferase subunit | 0.0194424 |
| HIVEP2 | human immunodeficiency virus type I enhancer binding protein 2 | 0.0190477 |
| BRD2 | bromodomain containing 2 | 0.0190252 |
| SRSF4 | serine/arginine-rich splicing factor 4 | 0.0187996 |
| GOLGA3 | golgin A3 | 0.0187151 |
| SRRM2 | serine/arginine repetitive matrix 2 | 0.0187076 |
| DENND1A | DENN/MADD domain containing 1A | 0.0186693 |
| PGAM4 | phosphoglycerate mutase family member 4 | 0.018533 |
| NCOR2 | nuclear receptor corepressor 2 | 0.0184707 |
| PRRC2C | proline-rich coiled-coil 2C | 0.0182781 |
| EIF4H | eukaryotic translation initiation factor 4H | 0.0182684 |
| BHLHE40 | basic helix-loop-helix family, member e40 | 0.0179044 |
| CLTC | clathrin, heavy chain (Hc) | 0.0176418 |
| EIF3A | eukaryotic translation initiation factor 3, subunit A | 0.0176195 |
| SPAG9 | sperm associated antigen 9 | 0.0173657 |
| PPP1R15A | protein phosphatase 1, regulatory subunit 15A | 0.017353 |
| PRKRIP1 | PRKR interacting protein 1 (IL11 inducible) | 0.0172566 |
| AP2B1 | adaptor-related protein complex 2, beta 1 subunit | 0.0172271 |
| MARCHF4 | membrane associated ring-CH-type finger 4 | 0.0172024 |
| EIF2AK3 | eukaryotic translation initiation factor 2-alpha kinase 3 | 0.0171981 |
| DHFR | dihydrofolate reductase | 0.0167653 |
| NABP1 | nucleic acid binding protein 1 | 0.0166004 |
| KDM6B | lysine (K)-specific demethylase 6B | 0.0163992 |
| UBR4 | ubiquitin protein ligase E3 component n-recognin 4 | 0.0163834 |
| ESYT2 | extended synaptotagmin-like protein 2 | 0.0163415 |
| ASH1L | ash1 (absent, small, or homeotic)-like (Drosophila) | 0.0160751 |
| ATP6V0A1 | ATPase, H+ transporting, lysosomal V0 subunit a1 | 0.0158124 |
| HADHA | hydroxyacyl-CoA dehydrogenase/3-ketoacyl-CoA thiolase/enoyl-CoA hydratase (trifunctional protein), alpha subunit | 0.0156234 |
| KAT6A | K(lysine) acetyltransferase 6A | 0.0155349 |
| NFAT5 | nuclear factor of activated T-cells 5, tonicity-responsive | 0.0155051 |
| FAM114A1 | family with sequence similarity 114, member A1 | 0.0154435 |
| SEC16A | SEC16 homolog A (S. cerevisiae) | 0.0153657 |
| WDR43 | WD repeat domain 43 | 0.0152681 |
| LEMD3 | LEM domain containing 3 | 0.0151241 |
| ANKZF1 | ankyrin repeat and zinc finger domain containing 1 | 0.0150676 |
| PNN | pinin, desmosome associated protein | 0.0150211 |
| EZR | ezrin | 0.0150149 |
| MYPN | myopalladin | 0.0149707 |
| SRRM1 | serine/arginine repetitive matrix 1 | 0.0149279 |
| H1-4 | H1.4 linker histone, cluster member | 0.014707 |
| SRP54 | signal recognition particle 54kDa | 0.0146485 |
| HSPA5 | heat shock 70kDa protein 5 (glucose-regulated protein, 78kDa) | 0.0146055 |
| ZFC3H1 | zinc finger, C3H1-type containing | 0.0143711 |
| NFE2L1 | nuclear factor, erythroid 2-like 1 | 0.0143417 |
| LRRC23 | leucine rich repeat containing 23 | 0.014341 |
| ATF6 | activating transcription factor 6 | 0.0143017 |
| KIF5B | kinesin family member 5B | 0.0142233 |
| IQGAP1 | IQ motif containing GTPase activating protein 1 | 0.0141759 |
| SAMD4A | sterile alpha motif domain containing 4A | 0.0141067 |
| DOT1L | DOT1-like histone H3K79 methyltransferase | 0.0140922 |
| RLF | rearranged L-myc fusion | 0.0140884 |
| PCLO | piccolo presynaptic cytomatrix protein | 0.0140345 |
| KIF1A | kinesin family member 1A | 0.0139583 |
| H1-0 | H1.0 linker histone | 0.0137046 |
| GOLGB1 | golgin B1 | 0.0135112 |
| TMF1 | TATA element modulatory factor 1 | 0.0134261 |
| USP53 | ubiquitin specific peptidase 53 | 0.0133852 |
| DCAF8 | DDB1 and CUL4 associated factor 8 | 0.0133415 |
| PPFIA1 | protein tyrosine phosphatase, receptor type, f polypeptide (PTPRF), interacting protein (liprin), alpha 1 | 0.0132791 |
| NUMA1 | nuclear mitotic apparatus protein 1 | 0.0132269 |
| MKI67 | marker of proliferation Ki-67 | 0.0132062 |
| TXNRD1 | thioredoxin reductase 1 | 0.0131888 |
| PRRC2A | proline-rich coiled-coil 2A | 0.0131545 |
| YY1AP1 | YY1 associated protein 1 | 0.0130746 |
| CAPRIN2 | caprin family member 2 | 0.0130082 |
| DGKD | diacylglycerol kinase, delta 130kDa | 0.0129657 |
| TMEM39A | transmembrane protein 39A | 0.0129628 |
| WNT2B | wingless-type MMTV integration site family, member 2B | 0.0129196 |
| MAT2A | methionine adenosyltransferase II, alpha | 0.0128743 |
| KIFC1 | kinesin family member C1 | 0.0128659 |
| KIF1B | kinesin family member 1B | 0.012849 |
| TMA7 | translation machinery associated 7 homolog (S. cerevisiae) | 0.0128313 |
| SNRNP200 | small nuclear ribonucleoprotein 200kDa (U5) | 0.0127769 |
| SHC1 | SHC (Src homology 2 domain containing) transforming protein 1 | 0.0127729 |
| Symbol | Name | Standardized Value |
|---|---|---|
| GAPDH | glyceraldehyde-3-phosphate dehydrogenase | -0.177106 |
| VIM | vimentin | -0.136524 |
| TMSB10 | thymosin beta 10 | -0.109019 |
| AKAP12 | A kinase (PRKA) anchor protein 12 | -0.100612 |
| PTMA | prothymosin, alpha | -0.0896294 |
| IMMP2L | IMP2 inner mitochondrial membrane peptidase-like (S. cerevisiae) | -0.0715839 |
| POTEF | POTE ankyrin domain family, member F | -0.068956 |
| RPL35A | ribosomal protein L35a | -0.0602793 |
| HSP90AA1 | heat shock protein 90kDa alpha (cytosolic), class A member 1 | -0.0586267 |
| RPS21 | ribosomal protein S21 | -0.0578118 |
| ERO1A | endoplasmic reticulum oxidoreductase 1 alpha | -0.0570246 |
| RPL23 | ribosomal protein L23 | -0.0568764 |
| MYL12B | myosin, light chain 12B, regulatory | -0.0562296 |
| TFPI2 | tissue factor pathway inhibitor 2 | -0.0546394 |
| ITPR2 | inositol 1,4,5-trisphosphate receptor, type 2 | -0.0546292 |
| PFN1 | profilin 1 | -0.0541774 |
| MT2A | metallothionein 2A | -0.0525076 |
| RPLP0 | ribosomal protein, large, P0 | -0.0520966 |
| OSMR | oncostatin M receptor | -0.0519194 |
| EIF2AK2 | eukaryotic translation initiation factor 2-alpha kinase 2 | -0.0510785 |
| RPS8 | ribosomal protein S8 | -0.0482543 |
| TPM4 | tropomyosin 4 | -0.0479968 |
| VDAC1 | voltage-dependent anion channel 1 | -0.047642 |
| HNRNPA2B1 | heterogeneous nuclear ribonucleoprotein A2/B1 | -0.0475154 |
| TANC2 | tetratricopeptide repeat, ankyrin repeat and coiled-coil containing 2 | -0.0473508 |
| IFI6 | interferon, alpha-inducible protein 6 | -0.0463839 |
| ENO1 | enolase 1, (alpha) | -0.0454403 |
| LDHB | lactate dehydrogenase B | -0.0431597 |
| RPL19 | ribosomal protein L19 | -0.0428962 |
| HLA-B | major histocompatibility complex, class I, B | -0.0425958 |
| CSDE1 | cold shock domain containing E1, RNA-binding | -0.042411 |
| RPLP1 | ribosomal protein, large, P1 | -0.0417168 |
| RPL37 | ribosomal protein L37 | -0.0409629 |
| RPS24 | ribosomal protein S24 | -0.0407584 |
| YWHAB | tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, beta | -0.0396866 |
| GRAMD1B | GRAM domain containing 1B | -0.0395835 |
| PNPT1 | polyribonucleotide nucleotidyltransferase 1 | -0.0386668 |
| CCT4 | chaperonin containing TCP1, subunit 4 (delta) | -0.0385035 |
| KRT18 | keratin 18, type I | -0.037925 |
| NCOA7 | nuclear receptor coactivator 7 | -0.0376721 |
| PABPC1 | poly(A) binding protein, cytoplasmic 1 | -0.0371475 |
| RPL12 | ribosomal protein L12 | -0.0370451 |
| PTPN12 | protein tyrosine phosphatase, non-receptor type 12 | -0.0360042 |
| RRM2 | ribonucleotide reductase M2 | -0.0357524 |
| WWOX | WW domain containing oxidoreductase | -0.0354061 |
| HSPD1 | heat shock 60kDa protein 1 (chaperonin) | -0.0346371 |
| LDHA | lactate dehydrogenase A | -0.0344797 |
| TPI1 | triosephosphate isomerase 1 | -0.0343252 |
| NIPBL | Nipped-B homolog (Drosophila) | -0.0339762 |
| CAPZA1 | capping protein (actin filament) muscle Z-line, alpha 1 | -0.0339195 |
| PGK1 | phosphoglycerate kinase 1 | -0.0337932 |
| ACTR2 | ARP2 actin-related protein 2 homolog (yeast) | -0.0335324 |
| SMURF2 | SMAD specific E3 ubiquitin protein ligase 2 | -0.0334888 |
| CDK17 | cyclin-dependent kinase 17 | -0.0331203 |
| TOP2A | topoisomerase (DNA) II alpha 170kDa | -0.0330617 |
| YBX1 | Y box binding protein 1 | -0.0328119 |
| SYNCRIP | synaptotagmin binding, cytoplasmic RNA interacting protein | -0.0327036 |
| TPM2 | tropomyosin 2 (beta) | -0.0325287 |
| PRKDC | protein kinase, DNA-activated, catalytic polypeptide | -0.0321421 |
| IGF1R | insulin-like growth factor 1 receptor | -0.0318444 |
| TPT1 | tumor protein, translationally-controlled 1 | -0.0314383 |
| PHF20 | PHD finger protein 20 | -0.0313882 |
| BBX | bobby sox homolog (Drosophila) | -0.031334 |
| ACTG1 | actin gamma 1 | -0.0312894 |
| BSG | basigin (Ok blood group) | -0.031212 |
| MTHFD1L | methylenetetrahydrofolate dehydrogenase (NADP+ dependent) 1-like | -0.0311108 |
| HSP90B1 | heat shock protein 90kDa beta (Grp94), member 1 | -0.0310683 |
| CSGALNACT1 | chondroitin sulfate N-acetylgalactosaminyltransferase 1 | -0.0309842 |
| PDIA3 | protein disulfide isomerase family A, member 3 | -0.0305601 |
| EIF5B | eukaryotic translation initiation factor 5B | -0.0297739 |
| SPDYA | speedy/RINGO cell cycle regulator family member A | -0.0297148 |
| RPL8 | ribosomal protein L8 | -0.0293565 |
| RPS15 | ribosomal protein S15 | -0.0293127 |
| YAP1 | Yes-associated protein 1 | -0.0293045 |
| S100A10 | S100 calcium binding protein A10 | -0.029122 |
| UBC | ubiquitin C | -0.0287708 |
| SERBP1 | SERPINE1 mRNA binding protein 1 | -0.028638 |
| RPS19 | ribosomal protein S19 | -0.0283329 |
| RPLP2 | ribosomal protein, large, P2 | -0.0283328 |
| KPNB1 | karyopherin (importin) beta 1 | -0.0282021 |
| RICTOR | RPTOR independent companion of MTOR, complex 2 | -0.028192 |
| HNRNPU | heterogeneous nuclear ribonucleoprotein U (scaffold attachment factor A) | -0.0279613 |
| PSMA7 | proteasome (prosome, macropain) subunit, alpha type, 7 | -0.0278691 |
| RPL9 | ribosomal protein L9 | -0.0277597 |
| NF1 | neurofibromin 1 | -0.0277039 |
| KLF6 | Kruppel-like factor 6 | -0.0276291 |
| RASSF8 | Ras association (RalGDS/AF-6) domain family (N-terminal) member 8 | -0.0275797 |
| PHIP | pleckstrin homology domain interacting protein | -0.0275637 |
| ITGB1 | integrin, beta 1 (fibronectin receptor, beta polypeptide, antigen CD29 includes MDF2, MSK12) | -0.0269802 |
| RPS10 | ribosomal protein S10 | -0.0267649 |
| P4HB | prolyl 4-hydroxylase, beta polypeptide | -0.026593 |
| RPS29 | ribosomal protein S29 | -0.0264383 |
| RPS4X | ribosomal protein S4, X-linked | -0.0262963 |
| OLA1 | Obg-like ATPase 1 | -0.0261437 |
| MARCKS | myristoylated alanine-rich protein kinase C substrate | -0.0261305 |
| CD2AP | CD2-associated protein | -0.0258805 |
| RPL26 | ribosomal protein L26 | -0.0258676 |
| TWF1 | twinfilin actin binding protein 1 | -0.0258227 |
| ZMYND8 | zinc finger, MYND-type containing 8 | -0.0257343 |
| RPS27 | ribosomal protein S27 | -0.0257334 |
