| Dataset | Tahoe Therapeutics Tahoe 100M Perturbation Atlas |
| Category | transcriptomics |
| Type | cell type |
| Description | Erythromycin perturbation in NCI-H2347 cell line (Tahoe Therapeutics) |
| Similar Terms | |
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200 genes differentially expressed following the Erythromycin_NCI-H2347 drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| BHLHE40 | basic helix-loop-helix family, member e40 | 0.0857719 |
| FTH1 | ferritin, heavy polypeptide 1 | 0.0786128 |
| RPS6 | ribosomal protein S6 | 0.0762218 |
| ASPH | aspartate beta-hydroxylase | 0.073195 |
| PABPC1 | poly(A) binding protein, cytoplasmic 1 | 0.0689214 |
| HSP90AB1 | heat shock protein 90kDa alpha (cytosolic), class B member 1 | 0.0660793 |
| NPM1 | nucleophosmin (nucleolar phosphoprotein B23, numatrin) | 0.0633837 |
| NUCKS1 | nuclear casein kinase and cyclin-dependent kinase substrate 1 | 0.0577288 |
| RACK1 | receptor for activated C kinase 1 | 0.0544914 |
| RPS2 | ribosomal protein S2 | 0.0536396 |
| RPS8 | ribosomal protein S8 | 0.0468439 |
| DCBLD2 | discoidin, CUB and LCCL domain containing 2 | 0.0458793 |
| EEF1G | eukaryotic translation elongation factor 1 gamma | 0.0452113 |
| GAPDH | glyceraldehyde-3-phosphate dehydrogenase | 0.0425602 |
| TUBA1B | tubulin, alpha 1b | 0.0415475 |
| RPL4 | ribosomal protein L4 | 0.0412488 |
| HSPA8 | heat shock 70kDa protein 8 | 0.041112 |
| GPX4 | glutathione peroxidase 4 | 0.0388275 |
| HMGB2 | high mobility group box 2 | 0.0384048 |
| EEF1A1 | eukaryotic translation elongation factor 1 alpha 1 | 0.0375986 |
| CALM2 | calmodulin 2 (phosphorylase kinase, delta) | 0.0356196 |
| RPS3 | ribosomal protein S3 | 0.033367 |
| NAP1L1 | nucleosome assembly protein 1-like 1 | 0.0310703 |
| HSP90AA1 | heat shock protein 90kDa alpha (cytosolic), class A member 1 | 0.0310546 |
| TOP2A | topoisomerase (DNA) II alpha 170kDa | 0.0307665 |
| RNF145 | ring finger protein 145 | 0.0300141 |
| ELF3 | E74-like factor 3 (ets domain transcription factor, epithelial-specific ) | 0.0293285 |
| HNRNPA1 | heterogeneous nuclear ribonucleoprotein A1 | 0.0293159 |
| YBX1 | Y box binding protein 1 | 0.0292974 |
| AREG | amphiregulin | 0.0275077 |
| FTL | ferritin, light polypeptide | 0.0273823 |
| PTMA | prothymosin, alpha | 0.0272633 |
| TFG | TRK-fused gene | 0.0259521 |
| SET | SET nuclear proto-oncogene | 0.0258262 |
| PGAM4 | phosphoglycerate mutase family member 4 | 0.0252681 |
| NUP58 | nucleoporin 58 | 0.0240937 |
| RPL17-C18ORF32 | RPL17-C18orf32 readthrough | 0.0238937 |
| FLNA | filamin A, alpha | 0.0235356 |
| UBE2C | ubiquitin-conjugating enzyme E2C | 0.0232643 |
| MAL2 | mal, T-cell differentiation protein 2 (gene/pseudogene) | 0.0231689 |
| TPM3 | tropomyosin 3 | 0.0230706 |
| RPL12 | ribosomal protein L12 | 0.0230445 |
| DSTN | destrin (actin depolymerizing factor) | 0.0228209 |
| RPS12 | ribosomal protein S12 | 0.0228186 |
| EIF4H | eukaryotic translation initiation factor 4H | 0.0226104 |
| TNIP1 | TNFAIP3 interacting protein 1 | 0.0225657 |
| RPL37A | ribosomal protein L37a | 0.0224381 |
| HDGF | hepatoma-derived growth factor | 0.0223628 |
| TMA7 | translation machinery associated 7 homolog (S. cerevisiae) | 0.0222345 |
| NAMPT | nicotinamide phosphoribosyltransferase | 0.0216128 |
| MSMO1 | methylsterol monooxygenase 1 | 0.0211996 |
| HMGN2 | high mobility group nucleosomal binding domain 2 | 0.0210834 |
| SEMA7A | semaphorin 7A, GPI membrane anchor (John Milton Hagen blood group) | 0.0205114 |
| RPL32 | ribosomal protein L32 | 0.0201074 |
| RPS17 | ribosomal protein S17 | 0.0199745 |
| CAPN2 | calpain 2, (m/II) large subunit | 0.0197733 |
| RPL26 | ribosomal protein L26 | 0.0196263 |
| RPL18 | ribosomal protein L18 | 0.019509 |
| RPL8 | ribosomal protein L8 | 0.0192995 |
| PLAU | plasminogen activator, urokinase | 0.0192654 |
| GADD45B | growth arrest and DNA-damage-inducible, beta | 0.0190886 |
| PABPN1 | poly(A) binding protein, nuclear 1 | 0.019041 |
| HNRNPDL | heterogeneous nuclear ribonucleoprotein D-like | 0.0188732 |
| YBX3 | Y box binding protein 3 | 0.0187271 |
| QKI | QKI, KH domain containing, RNA binding | 0.0187135 |
| ZFP36L1 | ZFP36 ring finger protein-like 1 | 0.0185973 |
| WDR43 | WD repeat domain 43 | 0.0185939 |
| RPL21 | ribosomal protein L21 | 0.0184259 |
| PAPOLA | poly(A) polymerase alpha | 0.0177029 |
| RPS27 | ribosomal protein S27 | 0.017661 |
| TAF1D | TATA box binding protein (TBP)-associated factor, RNA polymerase I, D, 41kDa | 0.0175504 |
| PA2G4 | proliferation-associated 2G4, 38kDa | 0.0175197 |
| RPS19 | ribosomal protein S19 | 0.0173433 |
| RPL10A | ribosomal protein L10a | 0.0171945 |
| LUC7L3 | LUC7-like 3 (S. cerevisiae) | 0.0171213 |
| PHLDA2 | pleckstrin homology-like domain, family A, member 2 | 0.0167435 |
| PPP1R15A | protein phosphatase 1, regulatory subunit 15A | 0.0165881 |
| H1-4 | H1.4 linker histone, cluster member | 0.0165392 |
| EIF4G1 | eukaryotic translation initiation factor 4 gamma, 1 | 0.016382 |
| RANBP1 | RAN binding protein 1 | 0.0157626 |
| GARS1 | glycyl-tRNA synthetase 1 | 0.0156149 |
| ATP5F1E | ATP synthase F1 subunit epsilon | 0.015571 |
| RPL13A | ribosomal protein L13a | 0.0155288 |
| NFKBIA | nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor, alpha | 0.015403 |
| PCBP2 | poly(rC) binding protein 2 | 0.015074 |
| BCLAF1 | BCL2-associated transcription factor 1 | 0.0149843 |
| MIS18BP1 | MIS18 binding protein 1 | 0.0148827 |
| G0S2 | G0/G1 switch 2 | 0.0147787 |
| MPRIP | myosin phosphatase Rho interacting protein | 0.0146974 |
| LRRFIP2 | leucine rich repeat (in FLII) interacting protein 2 | 0.0146557 |
| RPS14 | ribosomal protein S14 | 0.014534 |
| RPS16 | ribosomal protein S16 | 0.0143092 |
| TPI1 | triosephosphate isomerase 1 | 0.0142637 |
| RPL28 | ribosomal protein L28 | 0.0142269 |
| RPS7 | ribosomal protein S7 | 0.0141442 |
| ALCAM | activated leukocyte cell adhesion molecule | 0.0140871 |
| FXR1 | fragile X mental retardation, autosomal homolog 1 | 0.0140826 |
| CTNNB1 | catenin (cadherin-associated protein), beta 1, 88kDa | 0.0140772 |
| HDAC3 | histone deacetylase 3 | 0.0139146 |
| RTN4 | reticulon 4 | 0.0138451 |
| Symbol | Name | Standardized Value |
|---|---|---|
| NDRG1 | N-myc downstream regulated 1 | -0.188087 |
| FN1 | fibronectin 1 | -0.176821 |
| ITGA2 | integrin, alpha 2 (CD49B, alpha 2 subunit of VLA-2 receptor) | -0.144994 |
| LPP | LIM domain containing preferred translocation partner in lipoma | -0.128958 |
| ACTG1 | actin gamma 1 | -0.126406 |
| SAMD4A | sterile alpha motif domain containing 4A | -0.112235 |
| EXT1 | exostosin glycosyltransferase 1 | -0.108271 |
| HSP90B1 | heat shock protein 90kDa beta (Grp94), member 1 | -0.105737 |
| ERO1A | endoplasmic reticulum oxidoreductase 1 alpha | -0.102366 |
| LIMCH1 | LIM and calponin homology domains 1 | -0.102211 |
| POTEF | POTE ankyrin domain family, member F | -0.0931931 |
| IGFBP3 | insulin-like growth factor binding protein 3 | -0.0919811 |
| EFNA5 | ephrin-A5 | -0.0888954 |
| GRB10 | growth factor receptor-bound protein 10 | -0.085549 |
| ERBIN | erbb2 interacting protein | -0.0844129 |
| YWHAZ | tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, zeta | -0.0775717 |
| TMSB10 | thymosin beta 10 | -0.0759981 |
| FBXO32 | F-box protein 32 | -0.0727109 |
| ZSWIM6 | zinc finger, SWIM-type containing 6 | -0.0724445 |
| PLOD2 | procollagen-lysine, 2-oxoglutarate 5-dioxygenase 2 | -0.0715417 |
| FNDC3B | fibronectin type III domain containing 3B | -0.0705774 |
| LMO7 | LIM domain 7 | -0.0668265 |
| SEC31A | SEC31 homolog A (S. cerevisiae) | -0.0641167 |
| TRIO | trio Rho guanine nucleotide exchange factor | -0.0639935 |
| GBE1 | glucan (1,4-alpha-), branching enzyme 1 | -0.0633905 |
| P4HA1 | prolyl 4-hydroxylase, alpha polypeptide I | -0.0597756 |
| SMURF1 | SMAD specific E3 ubiquitin protein ligase 1 | -0.0586457 |
| WSB1 | WD repeat and SOCS box containing 1 | -0.0545435 |
| TPM4 | tropomyosin 4 | -0.0529952 |
| IFI16 | interferon, gamma-inducible protein 16 | -0.0529486 |
| PTK2 | protein tyrosine kinase 2 | -0.0525496 |
| CD2AP | CD2-associated protein | -0.0520069 |
| CANX | calnexin | -0.0517473 |
| TMSB4X | thymosin beta 4, X-linked | -0.0514833 |
| AHNAK | AHNAK nucleoprotein | -0.050986 |
| IFI27 | interferon, alpha-inducible protein 27 | -0.050232 |
| RALGPS2 | Ral GEF with PH domain and SH3 binding motif 2 | -0.0497076 |
| KMT2C | lysine (K)-specific methyltransferase 2C | -0.0493585 |
| UBE2H | ubiquitin-conjugating enzyme E2H | -0.0487524 |
| APLP2 | amyloid beta (A4) precursor-like protein 2 | -0.0477227 |
| TMEM165 | transmembrane protein 165 | -0.0475702 |
| PARP14 | poly (ADP-ribose) polymerase family, member 14 | -0.0465376 |
| RCOR1 | REST corepressor 1 | -0.0462006 |
| RPL35A | ribosomal protein L35a | -0.0455265 |
| MYO6 | myosin VI | -0.0453718 |
| GFPT1 | glutamine--fructose-6-phosphate transaminase 1 | -0.0443301 |
| CEP350 | centrosomal protein 350kDa | -0.0426513 |
| NIPBL | Nipped-B homolog (Drosophila) | -0.0421251 |
| ITCH | itchy E3 ubiquitin protein ligase | -0.0415177 |
| MBOAT2 | membrane bound O-acyltransferase domain containing 2 | -0.0414162 |
| MYO1E | myosin IE | -0.0413345 |
| AP3B1 | adaptor-related protein complex 3, beta 1 subunit | -0.040708 |
| LDHA | lactate dehydrogenase A | -0.0405606 |
| NAV2 | neuron navigator 2 | -0.0404172 |
| BBX | bobby sox homolog (Drosophila) | -0.0402649 |
| DTNA | dystrobrevin, alpha | -0.040069 |
| MDM2 | MDM2 proto-oncogene, E3 ubiquitin protein ligase | -0.0397918 |
| NF1 | neurofibromin 1 | -0.0396531 |
| TTC3 | tetratricopeptide repeat domain 3 | -0.0393402 |
| RNF213 | ring finger protein 213 | -0.0391653 |
| VCL | vinculin | -0.0391638 |
| DDX60 | DEAD (Asp-Glu-Ala-Asp) box polypeptide 60 | -0.0390134 |
| UBR5 | ubiquitin protein ligase E3 component n-recognin 5 | -0.0388058 |
| F3 | coagulation factor III (thromboplastin, tissue factor) | -0.0386318 |
| SOX4 | SRY (sex determining region Y)-box 4 | -0.0385627 |
| GPRC5A | G protein-coupled receptor, class C, group 5, member A | -0.038171 |
| TANC2 | tetratricopeptide repeat, ankyrin repeat and coiled-coil containing 2 | -0.0380392 |
| HLA-B | major histocompatibility complex, class I, B | -0.0379316 |
| RAI14 | retinoic acid induced 14 | -0.0374906 |
| HNRNPU | heterogeneous nuclear ribonucleoprotein U (scaffold attachment factor A) | -0.0374045 |
| FLNB | filamin B, beta | -0.0373039 |
| MX1 | MX dynamin-like GTPase 1 | -0.0372163 |
| FNIP1 | folliculin interacting protein 1 | -0.0370412 |
| MICAL3 | microtubule associated monooxygenase, calponin and LIM domain containing 3 | -0.0368147 |
| PDLIM5 | PDZ and LIM domain 5 | -0.0367967 |
| P4HB | prolyl 4-hydroxylase, beta polypeptide | -0.0367135 |
| STRN3 | striatin, calmodulin binding protein 3 | -0.036566 |
| ARF4 | ADP-ribosylation factor 4 | -0.0361204 |
| ARHGEF3 | Rho guanine nucleotide exchange factor (GEF) 3 | -0.0356162 |
| RAB7A | RAB7A, member RAS oncogene family | -0.0349571 |
| ANXA2 | annexin A2 | -0.0349502 |
| ARHGAP5 | Rho GTPase activating protein 5 | -0.0348062 |
| PKM | pyruvate kinase, muscle | -0.0346463 |
| PJA2 | praja ring finger 2, E3 ubiquitin protein ligase | -0.0343553 |
| CALU | calumenin | -0.0338936 |
| ABCA1 | ATP-binding cassette, sub-family A (ABC1), member 1 | -0.0336576 |
| KDM2A | lysine (K)-specific demethylase 2A | -0.0335416 |
| DYNC1H1 | dynein, cytoplasmic 1, heavy chain 1 | -0.0332949 |
| AGAP1 | ArfGAP with GTPase domain, ankyrin repeat and PH domain 1 | -0.0330981 |
| SERPINB1 | serpin peptidase inhibitor, clade B (ovalbumin), member 1 | -0.0330341 |
| BASP1 | brain abundant, membrane attached signal protein 1 | -0.0329878 |
| ABL2 | ABL proto-oncogene 2, non-receptor tyrosine kinase | -0.0324371 |
| ARID4B | AT rich interactive domain 4B (RBP1-like) | -0.0323731 |
| CTBP2 | C-terminal binding protein 2 | -0.0323178 |
| EIF2AK2 | eukaryotic translation initiation factor 2-alpha kinase 2 | -0.0322329 |
| RAB1A | RAB1A, member RAS oncogene family | -0.0321869 |
| AFF1 | AF4/FMR2 family, member 1 | -0.0321661 |
| BLZF1 | basic leucine zipper nuclear factor 1 | -0.0320883 |
| GOLGB1 | golgin B1 | -0.0316755 |
| COPB2 | coatomer protein complex, subunit beta 2 (beta prime) | -0.0315461 |
