| Dataset | Tahoe Therapeutics Tahoe 100M Perturbation Atlas |
| Category | transcriptomics |
| Type | cell type |
| Description | Erythromycin perturbation in NCI-H460 cell line (Tahoe Therapeutics) |
| Similar Terms | |
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200 genes differentially expressed following the Erythromycin_NCI-H460 drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| GAPDH | glyceraldehyde-3-phosphate dehydrogenase | 0.0935476 |
| MCL1 | myeloid cell leukemia 1 | 0.0889253 |
| PM20D1 | peptidase M20 domain containing 1 | 0.0838261 |
| KYNU | kynureninase | 0.0819243 |
| ELL2 | elongation factor, RNA polymerase II, 2 | 0.0717593 |
| GPRC5A | G protein-coupled receptor, class C, group 5, member A | 0.0716584 |
| ZC3HAV1 | zinc finger CCCH-type, antiviral 1 | 0.0715582 |
| SAMD4A | sterile alpha motif domain containing 4A | 0.0710091 |
| SRGAP1 | SLIT-ROBO Rho GTPase activating protein 1 | 0.0666261 |
| TBXT | T-box transcription factor T | 0.0665271 |
| DST | dystonin | 0.0646987 |
| ERRFI1 | ERBB receptor feedback inhibitor 1 | 0.0640874 |
| FTH1 | ferritin, heavy polypeptide 1 | 0.0631219 |
| EEF2 | eukaryotic translation elongation factor 2 | 0.0617057 |
| PHLDA1 | pleckstrin homology-like domain, family A, member 1 | 0.0575793 |
| PRRC2C | proline-rich coiled-coil 2C | 0.0561053 |
| EGR1 | early growth response 1 | 0.05477 |
| COL8A1 | collagen, type VIII, alpha 1 | 0.0532926 |
| NR4A1 | nuclear receptor subfamily 4, group A, member 1 | 0.0530199 |
| TGFBI | transforming growth factor, beta-induced, 68kDa | 0.0526656 |
| MYOF | myoferlin | 0.0521325 |
| FNDC3A | fibronectin type III domain containing 3A | 0.0518308 |
| PCBP2 | poly(rC) binding protein 2 | 0.0513155 |
| HERC4 | HECT and RLD domain containing E3 ubiquitin protein ligase 4 | 0.0509373 |
| CDH11 | cadherin 11, type 2, OB-cadherin (osteoblast) | 0.0499653 |
| CRIM1 | cysteine rich transmembrane BMP regulator 1 (chordin-like) | 0.0476156 |
| BASP1 | brain abundant, membrane attached signal protein 1 | 0.0462609 |
| TNFAIP3 | tumor necrosis factor, alpha-induced protein 3 | 0.0453785 |
| CD55 | CD55 molecule, decay accelerating factor for complement (Cromer blood group) | 0.0448412 |
| LIMCH1 | LIM and calponin homology domains 1 | 0.0446826 |
| MSN | moesin | 0.0439731 |
| RPS2 | ribosomal protein S2 | 0.0437752 |
| PDLIM5 | PDZ and LIM domain 5 | 0.0436972 |
| GDA | guanine deaminase | 0.0421828 |
| NCOR2 | nuclear receptor corepressor 2 | 0.0400758 |
| CHD1 | chromodomain helicase DNA binding protein 1 | 0.0393518 |
| SMOC1 | SPARC related modular calcium binding 1 | 0.0389345 |
| TGFBR1 | transforming growth factor, beta receptor 1 | 0.0387489 |
| EEF1A1 | eukaryotic translation elongation factor 1 alpha 1 | 0.0387049 |
| DOCK5 | dedicator of cytokinesis 5 | 0.0376772 |
| BAZ2A | bromodomain adjacent to zinc finger domain, 2A | 0.0375476 |
| VCL | vinculin | 0.0374927 |
| ATP2B1 | ATPase, Ca++ transporting, plasma membrane 1 | 0.0368579 |
| SLC39A8 | solute carrier family 39 (zinc transporter), member 8 | 0.035998 |
| TOP2A | topoisomerase (DNA) II alpha 170kDa | 0.0359125 |
| GRAMD1B | GRAM domain containing 1B | 0.0352277 |
| PITPNC1 | phosphatidylinositol transfer protein, cytoplasmic 1 | 0.034573 |
| LAMA1 | laminin, alpha 1 | 0.0344815 |
| CENPF | centromere protein F, 350/400kDa | 0.0344475 |
| EPB41L3 | erythrocyte membrane protein band 4.1-like 3 | 0.0338055 |
| EFNA5 | ephrin-A5 | 0.0334686 |
| PGAM4 | phosphoglycerate mutase family member 4 | 0.0334319 |
| LAMA5 | laminin, alpha 5 | 0.0333904 |
| VMP1 | vacuole membrane protein 1 | 0.0333126 |
| FLNB | filamin B, beta | 0.0333115 |
| TM4SF1 | transmembrane 4 L six family member 1 | 0.0331307 |
| STC1 | stanniocalcin 1 | 0.032786 |
| NR4A3 | nuclear receptor subfamily 4, group A, member 3 | 0.0326834 |
| EZR | ezrin | 0.0326124 |
| ITPRID2 | ITPR interacting domain containing 2 | 0.0325272 |
| ATP1B3 | ATPase, Na+/K+ transporting, beta 3 polypeptide | 0.0324216 |
| MKI67 | marker of proliferation Ki-67 | 0.0321878 |
| INHBA | inhibin, beta A | 0.0318967 |
| SLC38A2 | solute carrier family 38, member 2 | 0.031755 |
| CTIF | CBP80/20-dependent translation initiation factor | 0.0311092 |
| NPAS2 | neuronal PAS domain protein 2 | 0.0310191 |
| SLC2A13 | solute carrier family 2 (facilitated glucose transporter), member 13 | 0.0306492 |
| PABPC1 | poly(A) binding protein, cytoplasmic 1 | 0.0306272 |
| FLNA | filamin A, alpha | 0.0300874 |
| PPFIBP1 | PTPRF interacting protein, binding protein 1 (liprin beta 1) | 0.0299801 |
| TRIO | trio Rho guanine nucleotide exchange factor | 0.0299267 |
| NR4A2 | nuclear receptor subfamily 4, group A, member 2 | 0.0294893 |
| CD109 | CD109 molecule | 0.0290582 |
| NCAM1 | neural cell adhesion molecule 1 | 0.0284281 |
| IGFBP3 | insulin-like growth factor binding protein 3 | 0.0283862 |
| IGF2BP3 | insulin-like growth factor 2 mRNA binding protein 3 | 0.0280517 |
| YBX3 | Y box binding protein 3 | 0.0280477 |
| HSPA8 | heat shock 70kDa protein 8 | 0.0275658 |
| IL6 | interleukin 6 | 0.0266643 |
| ESYT2 | extended synaptotagmin-like protein 2 | 0.026472 |
| TNIP1 | TNFAIP3 interacting protein 1 | 0.026178 |
| DYNC1H1 | dynein, cytoplasmic 1, heavy chain 1 | 0.0260323 |
| GOLGA4 | golgin A4 | 0.0259861 |
| NUCKS1 | nuclear casein kinase and cyclin-dependent kinase substrate 1 | 0.025627 |
| FAM219A | family with sequence similarity 219, member A | 0.0254812 |
| HNRNPA1 | heterogeneous nuclear ribonucleoprotein A1 | 0.0254485 |
| EPHA4 | EPH receptor A4 | 0.0253949 |
| BRD4 | bromodomain containing 4 | 0.0251026 |
| BNIP3 | BCL2/adenovirus E1B 19kDa interacting protein 3 | 0.0249274 |
| ZC3H11A | zinc finger CCCH-type containing 11A | 0.0248691 |
| DUSP4 | dual specificity phosphatase 4 | 0.0245913 |
| PLEKHA5 | pleckstrin homology domain containing, family A member 5 | 0.0244556 |
| NFX1 | nuclear transcription factor, X-box binding 1 | 0.0243743 |
| BRD2 | bromodomain containing 2 | 0.0242564 |
| TBC1D8 | TBC1 domain family, member 8 (with GRAM domain) | 0.0238394 |
| HLA-A | major histocompatibility complex, class I, A | 0.0237322 |
| ZMIZ1 | zinc finger, MIZ-type containing 1 | 0.0236605 |
| CSNK1A1 | casein kinase 1, alpha 1 | 0.0235499 |
| RPS6 | ribosomal protein S6 | 0.0234742 |
| PDGFA | platelet-derived growth factor alpha polypeptide | 0.0230974 |
| Symbol | Name | Standardized Value |
|---|---|---|
| HSP90B1 | heat shock protein 90kDa beta (Grp94), member 1 | -0.217029 |
| HSPA5 | heat shock 70kDa protein 5 (glucose-regulated protein, 78kDa) | -0.201917 |
| FN1 | fibronectin 1 | -0.136366 |
| CXCL8 | chemokine (C-X-C motif) ligand 8 | -0.102397 |
| TPT1 | tumor protein, translationally-controlled 1 | -0.0905374 |
| RPS24 | ribosomal protein S24 | -0.0756868 |
| PTMA | prothymosin, alpha | -0.0750214 |
| RPLP1 | ribosomal protein, large, P1 | -0.0741797 |
| NALF1 | NALCN channel auxiliary factor 1 | -0.0727259 |
| VIM | vimentin | -0.0726175 |
| FTL | ferritin, light polypeptide | -0.0709626 |
| CANX | calnexin | -0.0664816 |
| COL5A2 | collagen, type V, alpha 2 | -0.0630778 |
| CDH13 | cadherin 13 | -0.0621863 |
| PDE4D | phosphodiesterase 4D, cAMP-specific | -0.0579581 |
| DPP10 | dipeptidyl-peptidase 10 (non-functional) | -0.0566868 |
| CYP1B1 | cytochrome P450, family 1, subfamily B, polypeptide 1 | -0.0563806 |
| SOD2 | superoxide dismutase 2, mitochondrial | -0.0558402 |
| RPLP0 | ribosomal protein, large, P0 | -0.0499901 |
| HSP90AA1 | heat shock protein 90kDa alpha (cytosolic), class A member 1 | -0.049627 |
| SMYD3 | SET and MYND domain containing 3 | -0.0471201 |
| RPL12 | ribosomal protein L12 | -0.0460097 |
| RPL35A | ribosomal protein L35a | -0.0458884 |
| HNRNPA2B1 | heterogeneous nuclear ribonucleoprotein A2/B1 | -0.0457648 |
| NAP1L1 | nucleosome assembly protein 1-like 1 | -0.045585 |
| RPL23 | ribosomal protein L23 | -0.0455228 |
| TXNRD1 | thioredoxin reductase 1 | -0.0448668 |
| NAMPT | nicotinamide phosphoribosyltransferase | -0.0443562 |
| RPL31 | ribosomal protein L31 | -0.0413904 |
| ERO1A | endoplasmic reticulum oxidoreductase 1 alpha | -0.0409629 |
| RPL38 | ribosomal protein L38 | -0.0408813 |
| PTPN12 | protein tyrosine phosphatase, non-receptor type 12 | -0.039799 |
| PDE3A | phosphodiesterase 3A, cGMP-inhibited | -0.0390704 |
| AGAP1 | ArfGAP with GTPase domain, ankyrin repeat and PH domain 1 | -0.0378222 |
| VDAC1 | voltage-dependent anion channel 1 | -0.0370937 |
| RPL19 | ribosomal protein L19 | -0.0353658 |
| RPL26 | ribosomal protein L26 | -0.0350104 |
| IER3 | immediate early response 3 | -0.0338125 |
| PTGR1 | prostaglandin reductase 1 | -0.0335871 |
| RASSF8 | Ras association (RalGDS/AF-6) domain family (N-terminal) member 8 | -0.032795 |
| PGK1 | phosphoglycerate kinase 1 | -0.0325526 |
| HSPD1 | heat shock 60kDa protein 1 (chaperonin) | -0.0324279 |
| LDHA | lactate dehydrogenase A | -0.0324245 |
| AKR1C1 | aldo-keto reductase family 1, member C1 | -0.0311675 |
| NCKAP5 | NCK-associated protein 5 | -0.0308722 |
| S100A10 | S100 calcium binding protein A10 | -0.0298856 |
| ANXA2 | annexin A2 | -0.0298331 |
| TENM3 | teneurin transmembrane protein 3 | -0.0297298 |
| WSB1 | WD repeat and SOCS box containing 1 | -0.0295989 |
| LMAN1 | lectin, mannose-binding, 1 | -0.0295487 |
| PDIA3 | protein disulfide isomerase family A, member 3 | -0.0295093 |
| PLCB1 | phospholipase C, beta 1 (phosphoinositide-specific) | -0.0293397 |
| PTPRM | protein tyrosine phosphatase, receptor type, M | -0.0289711 |
| RPS8 | ribosomal protein S8 | -0.0283944 |
| RPS27A | ribosomal protein S27a | -0.0276051 |
| TFPI2 | tissue factor pathway inhibitor 2 | -0.0274395 |
| S100A6 | S100 calcium binding protein A6 | -0.0270864 |
| RPL9 | ribosomal protein L9 | -0.0266385 |
| HNRNPU | heterogeneous nuclear ribonucleoprotein U (scaffold attachment factor A) | -0.0264865 |
| RPL34 | ribosomal protein L34 | -0.0261983 |
| AHNAK | AHNAK nucleoprotein | -0.0261544 |
| NPEPPS | aminopeptidase puromycin sensitive | -0.0258087 |
| SEMA3A | sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3A | -0.025491 |
| GNGT1 | guanine nucleotide binding protein (G protein), gamma transducing activity polypeptide 1 | -0.025406 |
| TMSB10 | thymosin beta 10 | -0.0252268 |
| RPLP2 | ribosomal protein, large, P2 | -0.0251526 |
| GFPT1 | glutamine--fructose-6-phosphate transaminase 1 | -0.0249019 |
| RPS29 | ribosomal protein S29 | -0.0241206 |
| ANXA1 | annexin A1 | -0.0238228 |
| RPS4X | ribosomal protein S4, X-linked | -0.0237357 |
| RPL39 | ribosomal protein L39 | -0.0235781 |
| PPP1R3C | protein phosphatase 1, regulatory subunit 3C | -0.0231815 |
| MAP7 | microtubule-associated protein 7 | -0.022872 |
| RPS27 | ribosomal protein S27 | -0.0228573 |
| TKT | transketolase | -0.0228314 |
| KPNB1 | karyopherin (importin) beta 1 | -0.0227716 |
| RPS19 | ribosomal protein S19 | -0.0225237 |
| PJA2 | praja ring finger 2, E3 ubiquitin protein ligase | -0.0218164 |
| PNRC1 | proline-rich nuclear receptor coactivator 1 | -0.0217618 |
| GNB1 | guanine nucleotide binding protein (G protein), beta polypeptide 1 | -0.0216352 |
| DHX9 | DEAH (Asp-Glu-Ala-His) box helicase 9 | -0.0215844 |
| RPL27A | ribosomal protein L27a | -0.0213615 |
| MAML3 | mastermind-like 3 (Drosophila) | -0.0212825 |
| SLC25A36 | solute carrier family 25 (pyrimidine nucleotide carrier), member 36 | -0.0211492 |
| KDM3A | lysine (K)-specific demethylase 3A | -0.0210732 |
| NCOA7 | nuclear receptor coactivator 7 | -0.0210693 |
| PDIA4 | protein disulfide isomerase family A, member 4 | -0.0208972 |
| LSAMP | limbic system-associated membrane protein | -0.0206391 |
| CTSL | cathepsin L | -0.0203507 |
| TBL1XR1 | transducin (beta)-like 1 X-linked receptor 1 | -0.0202624 |
| RANBP17 | RAN binding protein 17 | -0.0201553 |
| CACNA2D3 | calcium channel, voltage-dependent, alpha 2/delta subunit 3 | -0.0201405 |
| HIF1A | hypoxia inducible factor 1, alpha subunit (basic helix-loop-helix transcription factor) | -0.0201206 |
| RPL13A | ribosomal protein L13a | -0.0198871 |
| IGF1R | insulin-like growth factor 1 receptor | -0.019875 |
| TNPO1 | transportin 1 | -0.0197257 |
| OLA1 | Obg-like ATPase 1 | -0.0194857 |
| AUTS2 | autism susceptibility candidate 2 | -0.0194477 |
| USP3 | ubiquitin specific peptidase 3 | -0.0193817 |
| SSBP2 | single-stranded DNA binding protein 2 | -0.0192998 |
