| Dataset | Tahoe Therapeutics Tahoe 100M Perturbation Atlas |
| Category | transcriptomics |
| Type | cell type |
| Description | Erythromycin perturbation in SNU-423 cell line (Tahoe Therapeutics) |
| Similar Terms | |
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200 genes differentially expressed following the Erythromycin_SNU-423 drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| HSP90AB1 | heat shock protein 90kDa alpha (cytosolic), class B member 1 | 0.076423 |
| EEF2 | eukaryotic translation elongation factor 2 | 0.0518565 |
| PABPC1 | poly(A) binding protein, cytoplasmic 1 | 0.051475 |
| UGCG | UDP-glucose ceramide glucosyltransferase | 0.0444987 |
| MYH9 | myosin, heavy chain 9, non-muscle | 0.0433497 |
| OGA | O-GlcNAcase | 0.0427215 |
| ELL2 | elongation factor, RNA polymerase II, 2 | 0.0413543 |
| NPM1 | nucleophosmin (nucleolar phosphoprotein B23, numatrin) | 0.0407496 |
| GAPDH | glyceraldehyde-3-phosphate dehydrogenase | 0.0393931 |
| RPS2 | ribosomal protein S2 | 0.0385834 |
| RPS6 | ribosomal protein S6 | 0.0374771 |
| ATP13A3 | ATPase type 13A3 | 0.0350734 |
| MXI1 | MAX interactor 1, dimerization protein | 0.0350606 |
| LAMP2 | lysosomal-associated membrane protein 2 | 0.033051 |
| ANLN | anillin, actin binding protein | 0.0328664 |
| TSC22D2 | TSC22 domain family, member 2 | 0.0323761 |
| FLNA | filamin A, alpha | 0.0319844 |
| PCBP2 | poly(rC) binding protein 2 | 0.0314747 |
| EEF1A1 | eukaryotic translation elongation factor 1 alpha 1 | 0.0303884 |
| FTH1 | ferritin, heavy polypeptide 1 | 0.0298797 |
| HELZ | helicase with zinc finger | 0.0295098 |
| NUCKS1 | nuclear casein kinase and cyclin-dependent kinase substrate 1 | 0.0290869 |
| ESYT2 | extended synaptotagmin-like protein 2 | 0.0268381 |
| HNRNPA1 | heterogeneous nuclear ribonucleoprotein A1 | 0.0253912 |
| EIF1 | eukaryotic translation initiation factor 1 | 0.0245581 |
| SDC4 | syndecan 4 | 0.0245106 |
| KDM3A | lysine (K)-specific demethylase 3A | 0.0244517 |
| PGAM4 | phosphoglycerate mutase family member 4 | 0.0238082 |
| RPL4 | ribosomal protein L4 | 0.0237362 |
| UBR2 | ubiquitin protein ligase E3 component n-recognin 2 | 0.0236172 |
| PNISR | PNN-interacting serine/arginine-rich protein | 0.0230749 |
| BHLHE40 | basic helix-loop-helix family, member e40 | 0.0215744 |
| PUM2 | pumilio RNA-binding family member 2 | 0.0215344 |
| UBA6 | ubiquitin-like modifier activating enzyme 6 | 0.0214223 |
| P4HA1 | prolyl 4-hydroxylase, alpha polypeptide I | 0.021401 |
| MKI67 | marker of proliferation Ki-67 | 0.0208504 |
| CCNL1 | cyclin L1 | 0.0208263 |
| EZR | ezrin | 0.0200732 |
| RICTOR | RPTOR independent companion of MTOR, complex 2 | 0.0198527 |
| RNF145 | ring finger protein 145 | 0.0196986 |
| RBM39 | RNA binding motif protein 39 | 0.0188154 |
| RLF | rearranged L-myc fusion | 0.0187728 |
| NONO | non-POU domain containing, octamer-binding | 0.0187711 |
| TIAL1 | TIA1 cytotoxic granule-associated RNA binding protein-like 1 | 0.0185248 |
| TPM3 | tropomyosin 3 | 0.0174988 |
| PHIP | pleckstrin homology domain interacting protein | 0.0172986 |
| SRRM1 | serine/arginine repetitive matrix 1 | 0.0172481 |
| HIF1A | hypoxia inducible factor 1, alpha subunit (basic helix-loop-helix transcription factor) | 0.0172309 |
| MLLT10 | myeloid/lymphoid or mixed-lineage leukemia (trithorax homolog, Drosophila); translocated to, 10 | 0.0171764 |
| TMF1 | TATA element modulatory factor 1 | 0.0166461 |
| GOLGA4 | golgin A4 | 0.0166248 |
| LUC7L3 | LUC7-like 3 (S. cerevisiae) | 0.0165595 |
| SNX3 | sorting nexin 3 | 0.0165139 |
| CENPF | centromere protein F, 350/400kDa | 0.0163743 |
| CKAP5 | cytoskeleton associated protein 5 | 0.01632 |
| NAP1L1 | nucleosome assembly protein 1-like 1 | 0.0161286 |
| EIF4H | eukaryotic translation initiation factor 4H | 0.016048 |
| NUP153 | nucleoporin 153kDa | 0.0160411 |
| SNX2 | sorting nexin 2 | 0.0159076 |
| PTBP3 | polypyrimidine tract binding protein 3 | 0.0158864 |
| NPEPPS | aminopeptidase puromycin sensitive | 0.0158818 |
| USP37 | ubiquitin specific peptidase 37 | 0.0157411 |
| TEX10 | testis expressed 10 | 0.015636 |
| CALM2 | calmodulin 2 (phosphorylase kinase, delta) | 0.0155569 |
| DHFR | dihydrofolate reductase | 0.0153841 |
| NCKAP1 | NCK-associated protein 1 | 0.0153498 |
| WAC | WW domain containing adaptor with coiled-coil | 0.0151029 |
| EIF2S3 | eukaryotic translation initiation factor 2, subunit 3 gamma, 52kDa | 0.0150265 |
| MARCHF6 | membrane associated ring-CH-type finger 6 | 0.0149719 |
| WDR43 | WD repeat domain 43 | 0.0149672 |
| SPAG9 | sperm associated antigen 9 | 0.0149126 |
| SFTPA2 | surfactant protein A2 | 0.0147862 |
| TOP2B | topoisomerase (DNA) II beta 180kDa | 0.0146757 |
| ARL8B | ADP-ribosylation factor-like 8B | 0.0145857 |
| TFG | TRK-fused gene | 0.014508 |
| TOP2A | topoisomerase (DNA) II alpha 170kDa | 0.0144755 |
| BTAF1 | BTAF1 RNA polymerase II, B-TFIID transcription factor-associated, 170kDa | 0.0144626 |
| NT5C2 | 5'-nucleotidase, cytosolic II | 0.0144519 |
| CHD1 | chromodomain helicase DNA binding protein 1 | 0.0144513 |
| FHIP1A | FHF complex subunit HOOK interacting protein 1A | 0.014448 |
| PRRC2C | proline-rich coiled-coil 2C | 0.0143506 |
| PER1 | period circadian clock 1 | 0.0142741 |
| BCLAF1 | BCL2-associated transcription factor 1 | 0.0141889 |
| CD99 | CD99 molecule | 0.0140784 |
| ZNF292 | zinc finger protein 292 | 0.014064 |
| CTNNB1 | catenin (cadherin-associated protein), beta 1, 88kDa | 0.0140399 |
| IPMK | inositol polyphosphate multikinase | 0.0140166 |
| TPD52 | tumor protein D52 | 0.0140125 |
| MIS18BP1 | MIS18 binding protein 1 | 0.0138577 |
| H1-4 | H1.4 linker histone, cluster member | 0.0138045 |
| DYRK1A | dual-specificity tyrosine-(Y)-phosphorylation regulated kinase 1A | 0.0137998 |
| LCORL | ligand dependent nuclear receptor corepressor-like | 0.0137526 |
| UBQLN1 | ubiquilin 1 | 0.0136537 |
| HNRNPH1 | heterogeneous nuclear ribonucleoprotein H1 (H) | 0.01363 |
| NGLY1 | N-glycanase 1 | 0.0134882 |
| TNRC6A | trinucleotide repeat containing 6A | 0.0134472 |
| YWHAG | tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, gamma | 0.0134263 |
| NUP58 | nucleoporin 58 | 0.0131811 |
| NEK7 | NIMA-related kinase 7 | 0.0131753 |
| CREBRF | CREB3 regulatory factor | 0.0131693 |
| Symbol | Name | Standardized Value |
|---|---|---|
| VIM | vimentin | -0.192862 |
| SOD2 | superoxide dismutase 2, mitochondrial | -0.12772 |
| CD44 | CD44 molecule (Indian blood group) | -0.1221 |
| IQCJ-SCHIP1 | IQCJ-SCHIP1 readthrough | -0.116994 |
| GLIS3 | GLIS family zinc finger 3 | -0.107277 |
| IGFBP3 | insulin-like growth factor binding protein 3 | -0.10671 |
| HSPA5 | heat shock 70kDa protein 5 (glucose-regulated protein, 78kDa) | -0.0979655 |
| HSP90B1 | heat shock protein 90kDa beta (Grp94), member 1 | -0.0829796 |
| FRMD4A | FERM domain containing 4A | -0.0805842 |
| HMGA2 | high mobility group AT-hook 2 | -0.0787904 |
| KCNMA1 | potassium channel, calcium activated large conductance subfamily M alpha, member 1 | -0.0780324 |
| HLA-B | major histocompatibility complex, class I, B | -0.077745 |
| EXT1 | exostosin glycosyltransferase 1 | -0.0762976 |
| GBE1 | glucan (1,4-alpha-), branching enzyme 1 | -0.0733804 |
| AGAP1 | ArfGAP with GTPase domain, ankyrin repeat and PH domain 1 | -0.0707769 |
| VCL | vinculin | -0.0702935 |
| AKAP12 | A kinase (PRKA) anchor protein 12 | -0.0670895 |
| COL6A3 | collagen, type VI, alpha 3 | -0.0664807 |
| CDH13 | cadherin 13 | -0.0628465 |
| IER3 | immediate early response 3 | -0.0623333 |
| PDE10A | phosphodiesterase 10A | -0.0617491 |
| LDHA | lactate dehydrogenase A | -0.0614688 |
| BICC1 | BicC family RNA binding protein 1 | -0.060998 |
| IMMP2L | IMP2 inner mitochondrial membrane peptidase-like (S. cerevisiae) | -0.0562824 |
| MAGI2 | membrane associated guanylate kinase, WW and PDZ domain containing 2 | -0.0562147 |
| DIAPH2 | diaphanous-related formin 2 | -0.0551842 |
| ZSWIM6 | zinc finger, SWIM-type containing 6 | -0.0547513 |
| DCBLD2 | discoidin, CUB and LCCL domain containing 2 | -0.0540833 |
| VCAN | versican | -0.0535498 |
| FN1 | fibronectin 1 | -0.0524758 |
| DST | dystonin | -0.0520678 |
| SDK1 | sidekick cell adhesion molecule 1 | -0.0509186 |
| PLIN2 | perilipin 2 | -0.0498673 |
| TANC2 | tetratricopeptide repeat, ankyrin repeat and coiled-coil containing 2 | -0.0486377 |
| GRIN2A | glutamate receptor, ionotropic, N-methyl D-aspartate 2A | -0.0483348 |
| EDIL3 | EGF-like repeats and discoidin I-like domains 3 | -0.0476489 |
| ATXN1 | ataxin 1 | -0.0475047 |
| P4HB | prolyl 4-hydroxylase, beta polypeptide | -0.0458205 |
| HDAC9 | histone deacetylase 9 | -0.0448523 |
| CANX | calnexin | -0.0429216 |
| SMYD3 | SET and MYND domain containing 3 | -0.042018 |
| ENO1 | enolase 1, (alpha) | -0.0416295 |
| TPM4 | tropomyosin 4 | -0.0414288 |
| ZBTB20 | zinc finger and BTB domain containing 20 | -0.0412342 |
| PAPPA | pregnancy-associated plasma protein A, pappalysin 1 | -0.0412101 |
| ZMYND8 | zinc finger, MYND-type containing 8 | -0.0402145 |
| MARCKS | myristoylated alanine-rich protein kinase C substrate | -0.0400041 |
| NAV1 | neuron navigator 1 | -0.0394958 |
| FNDC3B | fibronectin type III domain containing 3B | -0.0392772 |
| LRRFIP1 | leucine rich repeat (in FLII) interacting protein 1 | -0.0392137 |
| IL1RAPL1 | interleukin 1 receptor accessory protein-like 1 | -0.0381861 |
| RNF213 | ring finger protein 213 | -0.0379694 |
| GPC6 | glypican 6 | -0.0373971 |
| EGFR | epidermal growth factor receptor | -0.0372341 |
| CALR | calreticulin | -0.0368966 |
| ZBTB38 | zinc finger and BTB domain containing 38 | -0.036807 |
| TPT1 | tumor protein, translationally-controlled 1 | -0.036185 |
| RPS24 | ribosomal protein S24 | -0.0357248 |
| TFPI | tissue factor pathway inhibitor (lipoprotein-associated coagulation inhibitor) | -0.0355594 |
| ATRX | alpha thalassemia/mental retardation syndrome X-linked | -0.0353813 |
| TNS3 | tensin 3 | -0.0352949 |
| RBMS3 | RNA binding motif, single stranded interacting protein 3 | -0.0351682 |
| LPP | LIM domain containing preferred translocation partner in lipoma | -0.0348147 |
| ABCA1 | ATP-binding cassette, sub-family A (ABC1), member 1 | -0.0347928 |
| FRMPD4 | FERM and PDZ domain containing 4 | -0.0346498 |
| RAD51B | RAD51 paralog B | -0.0343785 |
| IFI16 | interferon, gamma-inducible protein 16 | -0.0338885 |
| NABP1 | nucleic acid binding protein 1 | -0.0335373 |
| TRIO | trio Rho guanine nucleotide exchange factor | -0.0325848 |
| TMSB10 | thymosin beta 10 | -0.0321494 |
| FBXL7 | F-box and leucine-rich repeat protein 7 | -0.0319473 |
| GOLGB1 | golgin B1 | -0.0318008 |
| C3 | complement component 3 | -0.0317865 |
| MORF4L2 | mortality factor 4 like 2 | -0.0312369 |
| ASPH | aspartate beta-hydroxylase | -0.0309582 |
| STAT1 | signal transducer and activator of transcription 1, 91kDa | -0.0307669 |
| ANKS1B | ankyrin repeat and sterile alpha motif domain containing 1B | -0.0303711 |
| RPL23 | ribosomal protein L23 | -0.0303387 |
| ADAM12 | ADAM metallopeptidase domain 12 | -0.0303089 |
| RPL35A | ribosomal protein L35a | -0.0299947 |
| KYNU | kynureninase | -0.0298569 |
| PNRC1 | proline-rich nuclear receptor coactivator 1 | -0.0295511 |
| UBE2E2 | ubiquitin-conjugating enzyme E2E 2 | -0.0295235 |
| PTPRK | protein tyrosine phosphatase, receptor type, K | -0.0294974 |
| PSD3 | pleckstrin and Sec7 domain containing 3 | -0.0293542 |
| NHS | Nance-Horan syndrome (congenital cataracts and dental anomalies) | -0.0288749 |
| SLC38A1 | solute carrier family 38, member 1 | -0.0288127 |
| GNB1 | guanine nucleotide binding protein (G protein), beta polypeptide 1 | -0.0287167 |
| AHNAK | AHNAK nucleoprotein | -0.0286501 |
| TPM1 | tropomyosin 1 (alpha) | -0.0282995 |
| SOX5 | SRY (sex determining region Y)-box 5 | -0.0282206 |
| ITGA2 | integrin, alpha 2 (CD49B, alpha 2 subunit of VLA-2 receptor) | -0.0280895 |
| TMEM132D | transmembrane protein 132D | -0.0280606 |
| MYCBP2 | MYC binding protein 2, E3 ubiquitin protein ligase | -0.0275613 |
| INTS6 | integrator complex subunit 6 | -0.027353 |
| PARP14 | poly (ADP-ribose) polymerase family, member 14 | -0.0271086 |
| AFF3 | AF4/FMR2 family, member 3 | -0.0270179 |
| SUPT3H | suppressor of Ty 3 homolog (S. cerevisiae) | -0.0263422 |
| RIGI | RNA sensor RIG-I | -0.0261452 |
| IFI6 | interferon, alpha-inducible protein 6 | -0.0259749 |
