| Dataset | Tahoe Therapeutics Tahoe 100M Perturbation Atlas |
| Category | transcriptomics |
| Type | cell type |
| Description | Erythromycin perturbation in SW 1088 cell line (Tahoe Therapeutics) |
| Similar Terms | |
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200 genes differentially expressed following the Erythromycin_SW 1088 drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| GAPDH | glyceraldehyde-3-phosphate dehydrogenase | 0.0953755 |
| STC1 | stanniocalcin 1 | 0.0881768 |
| FTH1 | ferritin, heavy polypeptide 1 | 0.0836658 |
| HYCC1 | hyccin PI4KA lipid kinase complex subunit 1 | 0.0743377 |
| NAMPT | nicotinamide phosphoribosyltransferase | 0.0726119 |
| ELL2 | elongation factor, RNA polymerase II, 2 | 0.0678692 |
| ATP13A3 | ATPase type 13A3 | 0.0508669 |
| TRA2A | transformer 2 alpha homolog (Drosophila) | 0.0484779 |
| HSPA5 | heat shock 70kDa protein 5 (glucose-regulated protein, 78kDa) | 0.0476827 |
| MAP1B | microtubule-associated protein 1B | 0.0439492 |
| TGFBI | transforming growth factor, beta-induced, 68kDa | 0.0430486 |
| BHLHE40 | basic helix-loop-helix family, member e40 | 0.0377858 |
| TFG | TRK-fused gene | 0.0371488 |
| IGFBP7 | insulin-like growth factor binding protein 7 | 0.0371378 |
| ERRFI1 | ERBB receptor feedback inhibitor 1 | 0.0366101 |
| HSP90AB1 | heat shock protein 90kDa alpha (cytosolic), class B member 1 | 0.0355538 |
| H3-3B | H3.3 histone B | 0.0353324 |
| ETS1 | v-ets avian erythroblastosis virus E26 oncogene homolog 1 | 0.0351836 |
| HMGA2 | high mobility group AT-hook 2 | 0.0339979 |
| GOLGA4 | golgin A4 | 0.0314971 |
| FAM13A | family with sequence similarity 13, member A | 0.0303263 |
| AVL9 | AVL9 homolog (S. cerevisiase) | 0.0300272 |
| SPARC | secreted protein, acidic, cysteine-rich (osteonectin) | 0.0297835 |
| PRRC1 | proline-rich coiled-coil 1 | 0.0291569 |
| B2M | beta-2-microglobulin | 0.0287933 |
| KCNMA1 | potassium channel, calcium activated large conductance subfamily M alpha, member 1 | 0.0281399 |
| SKIC3 | SKI3 subunit of superkiller complex | 0.0267089 |
| SRP54 | signal recognition particle 54kDa | 0.0262809 |
| IGFBP5 | insulin-like growth factor binding protein 5 | 0.0261671 |
| NAP1L1 | nucleosome assembly protein 1-like 1 | 0.0260584 |
| TRIP12 | thyroid hormone receptor interactor 12 | 0.0258211 |
| RAB8B | RAB8B, member RAS oncogene family | 0.0254595 |
| RSRC2 | arginine/serine-rich coiled-coil 2 | 0.0252553 |
| S100A9 | S100 calcium binding protein A9 | 0.0252332 |
| ITCH | itchy E3 ubiquitin protein ligase | 0.0249307 |
| DKK3 | dickkopf WNT signaling pathway inhibitor 3 | 0.0248631 |
| COL1A1 | collagen, type I, alpha 1 | 0.0240374 |
| PLAUR | plasminogen activator, urokinase receptor | 0.0239143 |
| ZNF292 | zinc finger protein 292 | 0.0235754 |
| TM4SF1 | transmembrane 4 L six family member 1 | 0.0231404 |
| MARCHF6 | membrane associated ring-CH-type finger 6 | 0.0229989 |
| RNF145 | ring finger protein 145 | 0.0228965 |
| MT1X | metallothionein 1X | 0.0227004 |
| LOX | lysyl oxidase | 0.0226718 |
| RTN4 | reticulon 4 | 0.0226523 |
| KMT2E | lysine (K)-specific methyltransferase 2E | 0.0224719 |
| YWHAZ | tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, zeta | 0.0222293 |
| HIF1A | hypoxia inducible factor 1, alpha subunit (basic helix-loop-helix transcription factor) | 0.0213795 |
| EIF1 | eukaryotic translation initiation factor 1 | 0.0213495 |
| DYRK1A | dual-specificity tyrosine-(Y)-phosphorylation regulated kinase 1A | 0.0212553 |
| TXNIP | thioredoxin interacting protein | 0.0211528 |
| ARID4B | AT rich interactive domain 4B (RBP1-like) | 0.0210484 |
| TMEM165 | transmembrane protein 165 | 0.0210253 |
| NT5C2 | 5'-nucleotidase, cytosolic II | 0.0209765 |
| CCNI | cyclin I | 0.0208903 |
| HIVEP3 | human immunodeficiency virus type I enhancer binding protein 3 | 0.0207985 |
| COL4A1 | collagen, type IV, alpha 1 | 0.0206668 |
| PRSS23 | protease, serine, 23 | 0.0206234 |
| PTBP2 | polypyrimidine tract binding protein 2 | 0.0205104 |
| KIAA0319L | KIAA0319-like | 0.0203779 |
| ADNP | activity-dependent neuroprotector homeobox | 0.0202207 |
| PRRC2C | proline-rich coiled-coil 2C | 0.0199868 |
| ARRDC3 | arrestin domain containing 3 | 0.0198849 |
| RNF24 | ring finger protein 24 | 0.0198822 |
| HLA-C | major histocompatibility complex, class I, C | 0.019637 |
| EHD2 | EH-domain containing 2 | 0.0196055 |
| AK1 | adenylate kinase 1 | 0.01957 |
| RBM39 | RNA binding motif protein 39 | 0.0195413 |
| PAG1 | phosphoprotein membrane anchor with glycosphingolipid microdomains 1 | 0.0195375 |
| GGT7 | gamma-glutamyltransferase 7 | 0.0192456 |
| PID1 | phosphotyrosine interaction domain containing 1 | 0.0192142 |
| SLC6A6 | solute carrier family 6 (neurotransmitter transporter), member 6 | 0.0188287 |
| RBPJ | recombination signal binding protein for immunoglobulin kappa J region | 0.0185576 |
| MYO9A | myosin IXA | 0.0185464 |
| THBS1 | thrombospondin 1 | 0.0184444 |
| HPCAL1 | hippocalcin-like 1 | 0.0183957 |
| CHIC2 | cysteine-rich hydrophobic domain 2 | 0.018329 |
| PIK3R1 | phosphoinositide-3-kinase, regulatory subunit 1 (alpha) | 0.0182678 |
| P4HA1 | prolyl 4-hydroxylase, alpha polypeptide I | 0.0182152 |
| RBM25 | RNA binding motif protein 25 | 0.0181428 |
| DPM1 | dolichyl-phosphate mannosyltransferase polypeptide 1, catalytic subunit | 0.018118 |
| SHB | Src homology 2 domain containing adaptor protein B | 0.0181015 |
| MICAL2 | microtubule associated monooxygenase, calponin and LIM domain containing 2 | 0.0180991 |
| PCCA | propionyl CoA carboxylase, alpha polypeptide | 0.0180288 |
| OAF | OAF homolog (Drosophila) | 0.0180211 |
| SERF2 | small EDRK-rich factor 2 | 0.0179296 |
| KIF1B | kinesin family member 1B | 0.0179267 |
| UGCG | UDP-glucose ceramide glucosyltransferase | 0.0178883 |
| RPL36 | ribosomal protein L36 | 0.0178749 |
| RARS1 | arginyl-tRNA synthetase 1 | 0.0177366 |
| LAMC1 | laminin, gamma 1 (formerly LAMB2) | 0.0177343 |
| TENT5A | terminal nucleotidyltransferase 5A | 0.0176351 |
| THOC2 | THO complex 2 | 0.0176189 |
| IRAK2 | interleukin-1 receptor-associated kinase 2 | 0.0176163 |
| TNKS | tankyrase, TRF1-interacting ankyrin-related ADP-ribose polymerase | 0.0176008 |
| DNAJC3 | DnaJ (Hsp40) homolog, subfamily C, member 3 | 0.0175818 |
| BMERB1 | bMERB domain containing 1 | 0.0173144 |
| PNISR | PNN-interacting serine/arginine-rich protein | 0.0173102 |
| WTAP | Wilms tumor 1 associated protein | 0.0172467 |
| UBE2B | ubiquitin-conjugating enzyme E2B | 0.0172087 |
| Symbol | Name | Standardized Value |
|---|---|---|
| IGFBP3 | insulin-like growth factor binding protein 3 | -0.260175 |
| COL6A3 | collagen, type VI, alpha 3 | -0.0846769 |
| CDH13 | cadherin 13 | -0.0770821 |
| CXCL8 | chemokine (C-X-C motif) ligand 8 | -0.063751 |
| TIMP3 | TIMP metallopeptidase inhibitor 3 | -0.0608502 |
| HSP90B1 | heat shock protein 90kDa beta (Grp94), member 1 | -0.0585712 |
| FN1 | fibronectin 1 | -0.0572972 |
| EGFR | epidermal growth factor receptor | -0.0547885 |
| POTEF | POTE ankyrin domain family, member F | -0.053081 |
| GBE1 | glucan (1,4-alpha-), branching enzyme 1 | -0.0516194 |
| ATXN1 | ataxin 1 | -0.0471735 |
| HNRNPC | heterogeneous nuclear ribonucleoprotein C (C1/C2) | -0.047068 |
| PKM | pyruvate kinase, muscle | -0.0469208 |
| VIM | vimentin | -0.0458407 |
| NDRG1 | N-myc downstream regulated 1 | -0.045597 |
| F3 | coagulation factor III (thromboplastin, tissue factor) | -0.0444099 |
| RAD51B | RAD51 paralog B | -0.0419315 |
| SOD2 | superoxide dismutase 2, mitochondrial | -0.0407142 |
| PRKCA | protein kinase C, alpha | -0.0404841 |
| ZSWIM6 | zinc finger, SWIM-type containing 6 | -0.0369905 |
| PSD3 | pleckstrin and Sec7 domain containing 3 | -0.0355156 |
| P4HB | prolyl 4-hydroxylase, beta polypeptide | -0.0339521 |
| PLOD2 | procollagen-lysine, 2-oxoglutarate 5-dioxygenase 2 | -0.0329045 |
| TMSB10 | thymosin beta 10 | -0.0314406 |
| ASCC3 | activating signal cointegrator 1 complex subunit 3 | -0.0314081 |
| HNRNPA2B1 | heterogeneous nuclear ribonucleoprotein A2/B1 | -0.0310182 |
| GFPT1 | glutamine--fructose-6-phosphate transaminase 1 | -0.0305405 |
| SDK1 | sidekick cell adhesion molecule 1 | -0.0302991 |
| NUFIP2 | nuclear fragile X mental retardation protein interacting protein 2 | -0.0298917 |
| MED13L | mediator complex subunit 13-like | -0.0295753 |
| TPM4 | tropomyosin 4 | -0.0295168 |
| TNS3 | tensin 3 | -0.0293651 |
| VEGFA | vascular endothelial growth factor A | -0.0293424 |
| TOP1 | topoisomerase (DNA) I | -0.0288347 |
| METTL15 | methyltransferase like 15 | -0.0287272 |
| APLP2 | amyloid beta (A4) precursor-like protein 2 | -0.0284232 |
| FNDC3B | fibronectin type III domain containing 3B | -0.0280007 |
| ZBTB20 | zinc finger and BTB domain containing 20 | -0.0279657 |
| BIRC6 | baculoviral IAP repeat containing 6 | -0.0279446 |
| ACTG1 | actin gamma 1 | -0.0278501 |
| ASPH | aspartate beta-hydroxylase | -0.0277259 |
| SEMA5A | sema domain, seven thrombospondin repeats (type 1 and type 1-like), transmembrane domain (TM) and short cytoplasmic domain, (semaphorin) 5A | -0.0277255 |
| LDHA | lactate dehydrogenase A | -0.0276802 |
| INTS6 | integrator complex subunit 6 | -0.026626 |
| NBAS | neuroblastoma amplified sequence | -0.0265345 |
| MCL1 | myeloid cell leukemia 1 | -0.0262654 |
| CCDC88A | coiled-coil domain containing 88A | -0.0260891 |
| ENO2 | enolase 2 (gamma, neuronal) | -0.025732 |
| PDE4D | phosphodiesterase 4D, cAMP-specific | -0.0252702 |
| UBAP2 | ubiquitin associated protein 2 | -0.0250584 |
| ZC3HAV1 | zinc finger CCCH-type, antiviral 1 | -0.0250576 |
| DTNA | dystrobrevin, alpha | -0.0247111 |
| USP34 | ubiquitin specific peptidase 34 | -0.0245735 |
| DDX17 | DEAD (Asp-Glu-Ala-Asp) box helicase 17 | -0.0243043 |
| HDAC9 | histone deacetylase 9 | -0.023343 |
| KYNU | kynureninase | -0.0233235 |
| CALR | calreticulin | -0.0231458 |
| LOXL2 | lysyl oxidase-like 2 | -0.0230957 |
| LMNA | lamin A/C | -0.0230552 |
| ITGB1 | integrin, beta 1 (fibronectin receptor, beta polypeptide, antigen CD29 includes MDF2, MSK12) | -0.0225104 |
| AFF3 | AF4/FMR2 family, member 3 | -0.0219754 |
| RBM33 | RNA binding motif protein 33 | -0.021893 |
| EPC2 | enhancer of polycomb homolog 2 (Drosophila) | -0.0216201 |
| ROBO1 | roundabout, axon guidance receptor, homolog 1 (Drosophila) | -0.0215262 |
| EXOC4 | exocyst complex component 4 | -0.0214762 |
| EHBP1 | EH domain binding protein 1 | -0.0212482 |
| TRIO | trio Rho guanine nucleotide exchange factor | -0.0209978 |
| DSTN | destrin (actin depolymerizing factor) | -0.0207875 |
| SPDYA | speedy/RINGO cell cycle regulator family member A | -0.0207614 |
| NALF1 | NALCN channel auxiliary factor 1 | -0.0203453 |
| PTPRM | protein tyrosine phosphatase, receptor type, M | -0.0202368 |
| COL7A1 | collagen, type VII, alpha 1 | -0.0200873 |
| SLC6A8 | solute carrier family 6 (neurotransmitter transporter), member 8 | -0.0198451 |
| MT2A | metallothionein 2A | -0.0196927 |
| MSN | moesin | -0.0195892 |
| TANC2 | tetratricopeptide repeat, ankyrin repeat and coiled-coil containing 2 | -0.0194746 |
| MYCBP2 | MYC binding protein 2, E3 ubiquitin protein ligase | -0.0191109 |
| ENO1 | enolase 1, (alpha) | -0.0190705 |
| MMP12 | matrix metallopeptidase 12 | -0.0188861 |
| MTHFD2 | methylenetetrahydrofolate dehydrogenase (NADP+ dependent) 2, methenyltetrahydrofolate cyclohydrolase | -0.0188546 |
| EXT1 | exostosin glycosyltransferase 1 | -0.0187996 |
| RASAL2 | RAS protein activator like 2 | -0.0183307 |
| RUNX1 | runt-related transcription factor 1 | -0.0183012 |
| GNB1 | guanine nucleotide binding protein (G protein), beta polypeptide 1 | -0.0182542 |
| CALM1 | calmodulin 1 (phosphorylase kinase, delta) | -0.0182324 |
| EDIL3 | EGF-like repeats and discoidin I-like domains 3 | -0.0182074 |
| INSIG1 | insulin induced gene 1 | -0.0181333 |
| ANKRD17 | ankyrin repeat domain 17 | -0.0181275 |
| SMG1 | SMG1 phosphatidylinositol 3-kinase-related kinase | -0.0180537 |
| COL6A1 | collagen, type VI, alpha 1 | -0.0179915 |
| RCOR1 | REST corepressor 1 | -0.0179451 |
| HP1BP3 | heterochromatin protein 1, binding protein 3 | -0.0179063 |
| ERC2 | ELKS/RAB6-interacting/CAST family member 2 | -0.017722 |
| ABL2 | ABL proto-oncogene 2, non-receptor tyrosine kinase | -0.0177061 |
| CALU | calumenin | -0.0175728 |
| PTPRK | protein tyrosine phosphatase, receptor type, K | -0.0174608 |
| EIF5AL1 | eukaryotic translation initiation factor 5A-like 1 | -0.0174494 |
| OGDH | oxoglutarate (alpha-ketoglutarate) dehydrogenase (lipoamide) | -0.0173886 |
| MAML3 | mastermind-like 3 (Drosophila) | -0.017222 |
| ZNF609 | zinc finger protein 609 | -0.0168613 |
