| Dataset | Tahoe Therapeutics Tahoe 100M Perturbation Atlas |
| Category | transcriptomics |
| Type | cell type |
| Description | Erythromycin perturbation in SW 900 cell line (Tahoe Therapeutics) |
| Similar Terms | |
| Downloads & Tools |
200 genes differentially expressed following the Erythromycin_SW 900 drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| GAPDH | glyceraldehyde-3-phosphate dehydrogenase | 0.145269 |
| FTH1 | ferritin, heavy polypeptide 1 | 0.120793 |
| MT2A | metallothionein 2A | 0.0923508 |
| HIF1A | hypoxia inducible factor 1, alpha subunit (basic helix-loop-helix transcription factor) | 0.0862565 |
| CYP1B1 | cytochrome P450, family 1, subfamily B, polypeptide 1 | 0.0810926 |
| PRRC2C | proline-rich coiled-coil 2C | 0.0773667 |
| PTGS2 | prostaglandin-endoperoxide synthase 2 (prostaglandin G/H synthase and cyclooxygenase) | 0.0520068 |
| RPS6 | ribosomal protein S6 | 0.0495657 |
| OSMR | oncostatin M receptor | 0.0487638 |
| CAB39 | calcium binding protein 39 | 0.0429247 |
| B4GALT5 | UDP-Gal:betaGlcNAc beta 1,4- galactosyltransferase, polypeptide 5 | 0.0418149 |
| SMOX | spermine oxidase | 0.039232 |
| ITGA2 | integrin, alpha 2 (CD49B, alpha 2 subunit of VLA-2 receptor) | 0.0387415 |
| NRIP1 | nuclear receptor interacting protein 1 | 0.0342688 |
| RPS27 | ribosomal protein S27 | 0.0339528 |
| GCC2 | GRIP and coiled-coil domain containing 2 | 0.0334703 |
| CD44 | CD44 molecule (Indian blood group) | 0.0326324 |
| EREG | epiregulin | 0.0304896 |
| RPL26 | ribosomal protein L26 | 0.0296697 |
| PELO | pelota homolog (Drosophila) | 0.0289825 |
| SOS1 | son of sevenless homolog 1 (Drosophila) | 0.0287735 |
| RPL12 | ribosomal protein L12 | 0.0284848 |
| CDCP1 | CUB domain containing protein 1 | 0.0282325 |
| TFPI | tissue factor pathway inhibitor (lipoprotein-associated coagulation inhibitor) | 0.0277671 |
| ETV6 | ets variant 6 | 0.0273344 |
| SYNJ2 | synaptojanin 2 | 0.0269689 |
| MKI67 | marker of proliferation Ki-67 | 0.0266018 |
| CENPF | centromere protein F, 350/400kDa | 0.0257349 |
| SPRED1 | sprouty-related, EVH1 domain containing 1 | 0.0256973 |
| HDGF | hepatoma-derived growth factor | 0.0248598 |
| CIRSR | corepressor of RBPJ and splicing regulator | 0.0247798 |
| NRP1 | neuropilin 1 | 0.0238627 |
| TXNRD1 | thioredoxin reductase 1 | 0.0237923 |
| RPS12 | ribosomal protein S12 | 0.0237531 |
| UGCG | UDP-glucose ceramide glucosyltransferase | 0.0235808 |
| ZFR | zinc finger RNA binding protein | 0.0233912 |
| AVL9 | AVL9 homolog (S. cerevisiase) | 0.0231394 |
| FAF2 | Fas associated factor family member 2 | 0.0229789 |
| MAP3K5 | mitogen-activated protein kinase kinase kinase 5 | 0.0228296 |
| ARHGEF12 | Rho guanine nucleotide exchange factor (GEF) 12 | 0.0225393 |
| ARID5B | AT rich interactive domain 5B (MRF1-like) | 0.0222627 |
| AKAP9 | A kinase (PRKA) anchor protein 9 | 0.022195 |
| SMURF2 | SMAD specific E3 ubiquitin protein ligase 2 | 0.021947 |
| UQCRB | ubiquinol-cytochrome c reductase binding protein | 0.0217109 |
| MAP3K9 | mitogen-activated protein kinase kinase kinase 9 | 0.0215985 |
| FMN1 | formin 1 | 0.021542 |
| HS2ST1 | heparan sulfate 2-O-sulfotransferase 1 | 0.0212797 |
| TMEM156 | transmembrane protein 156 | 0.0210182 |
| RNF24 | ring finger protein 24 | 0.0209245 |
| NAMPT | nicotinamide phosphoribosyltransferase | 0.0208979 |
| MGST1 | microsomal glutathione S-transferase 1 | 0.0206014 |
| TMCO1 | transmembrane and coiled-coil domains 1 | 0.0204825 |
| RPL9 | ribosomal protein L9 | 0.0204226 |
| RUNX2 | runt-related transcription factor 2 | 0.0202814 |
| RBM25 | RNA binding motif protein 25 | 0.0202251 |
| RPL36 | ribosomal protein L36 | 0.0201457 |
| RPL18 | ribosomal protein L18 | 0.0200465 |
| CTNND1 | catenin (cadherin-associated protein), delta 1 | 0.0199672 |
| OGA | O-GlcNAcase | 0.0195487 |
| RPLP0 | ribosomal protein, large, P0 | 0.0195451 |
| MNAT1 | MNAT CDK-activating kinase assembly factor 1 | 0.0195334 |
| GPAT3 | glycerol-3-phosphate acyltransferase 3 | 0.0194637 |
| PLAUR | plasminogen activator, urokinase receptor | 0.0194062 |
| TOP2A | topoisomerase (DNA) II alpha 170kDa | 0.0193478 |
| TPI1 | triosephosphate isomerase 1 | 0.0193306 |
| MCFD2 | multiple coagulation factor deficiency 2 | 0.0192973 |
| FTL | ferritin, light polypeptide | 0.019068 |
| TXNIP | thioredoxin interacting protein | 0.0189595 |
| ATP2B4 | ATPase, Ca++ transporting, plasma membrane 4 | 0.0189295 |
| TGFBR2 | transforming growth factor, beta receptor II (70/80kDa) | 0.0184811 |
| CCNJL | cyclin J-like | 0.0181672 |
| FBXL5 | F-box and leucine-rich repeat protein 5 | 0.018055 |
| FOXP1 | forkhead box P1 | 0.0180469 |
| RPLP1 | ribosomal protein, large, P1 | 0.0176715 |
| PNISR | PNN-interacting serine/arginine-rich protein | 0.0176419 |
| VPS54 | vacuolar protein sorting 54 homolog (S. cerevisiae) | 0.0175083 |
| RACK1 | receptor for activated C kinase 1 | 0.0172406 |
| ITGB5 | integrin, beta 5 | 0.0171648 |
| TBK1 | TANK-binding kinase 1 | 0.0170386 |
| KLHL5 | kelch-like family member 5 | 0.0170078 |
| RHOBTB3 | Rho-related BTB domain containing 3 | 0.0169547 |
| CD58 | CD58 molecule | 0.0166967 |
| EIF2AK1 | eukaryotic translation initiation factor 2-alpha kinase 1 | 0.0162743 |
| ELF2 | E74-like factor 2 (ets domain transcription factor) | 0.0161385 |
| SRP9 | signal recognition particle 9kDa | 0.0160527 |
| RPS2 | ribosomal protein S2 | 0.0159459 |
| DOCK5 | dedicator of cytokinesis 5 | 0.0159413 |
| SH3BP4 | SH3-domain binding protein 4 | 0.0158911 |
| SMIM14 | small integral membrane protein 14 | 0.0158861 |
| CAPZA1 | capping protein (actin filament) muscle Z-line, alpha 1 | 0.0158399 |
| SLC44A1 | solute carrier family 44 (choline transporter), member 1 | 0.0157171 |
| RPL28 | ribosomal protein L28 | 0.0156276 |
| RPL17-C18ORF32 | RPL17-C18orf32 readthrough | 0.0154227 |
| PLPP6 | phospholipid phosphatase 6 | 0.0152555 |
| ARID2 | AT rich interactive domain 2 (ARID, RFX-like) | 0.0151947 |
| ZMYND8 | zinc finger, MYND-type containing 8 | 0.0151931 |
| CKAP2 | cytoskeleton associated protein 2 | 0.0148843 |
| S100A6 | S100 calcium binding protein A6 | 0.0148232 |
| RPLP2 | ribosomal protein, large, P2 | 0.0147764 |
| RTN4 | reticulon 4 | 0.0147255 |
| Symbol | Name | Standardized Value |
|---|---|---|
| FN1 | fibronectin 1 | -0.232139 |
| NRG1 | neuregulin 1 | -0.229975 |
| NDRG1 | N-myc downstream regulated 1 | -0.134257 |
| HMGA2 | high mobility group AT-hook 2 | -0.116085 |
| HSP90B1 | heat shock protein 90kDa beta (Grp94), member 1 | -0.11507 |
| TRIO | trio Rho guanine nucleotide exchange factor | -0.114903 |
| HSPA5 | heat shock 70kDa protein 5 (glucose-regulated protein, 78kDa) | -0.101435 |
| KCNMA1 | potassium channel, calcium activated large conductance subfamily M alpha, member 1 | -0.0986734 |
| GBE1 | glucan (1,4-alpha-), branching enzyme 1 | -0.0955837 |
| GRB10 | growth factor receptor-bound protein 10 | -0.0891702 |
| SLC5A3 | solute carrier family 5 (sodium/myo-inositol cotransporter), member 3 | -0.0886595 |
| P4HB | prolyl 4-hydroxylase, beta polypeptide | -0.0863121 |
| CANX | calnexin | -0.0809322 |
| ZSWIM6 | zinc finger, SWIM-type containing 6 | -0.0796488 |
| MRPS6 | mitochondrial ribosomal protein S6 | -0.0796346 |
| LIMCH1 | LIM and calponin homology domains 1 | -0.0787715 |
| STC2 | stanniocalcin 2 | -0.0754597 |
| INTS6 | integrator complex subunit 6 | -0.0688777 |
| ABL2 | ABL proto-oncogene 2, non-receptor tyrosine kinase | -0.0643685 |
| EFNA5 | ephrin-A5 | -0.0615821 |
| ERRFI1 | ERBB receptor feedback inhibitor 1 | -0.0592783 |
| CTBP2 | C-terminal binding protein 2 | -0.0572531 |
| SLC2A3 | solute carrier family 2 (facilitated glucose transporter), member 3 | -0.0560844 |
| CADM1 | cell adhesion molecule 1 | -0.0545223 |
| SQSTM1 | sequestosome 1 | -0.0519923 |
| AEBP2 | AE binding protein 2 | -0.0512512 |
| VCL | vinculin | -0.0504867 |
| RAI14 | retinoic acid induced 14 | -0.0502821 |
| RABGEF1 | RAB guanine nucleotide exchange factor (GEF) 1 | -0.049866 |
| PLOD2 | procollagen-lysine, 2-oxoglutarate 5-dioxygenase 2 | -0.0483503 |
| MCL1 | myeloid cell leukemia 1 | -0.0464265 |
| SLC35F3 | solute carrier family 35, member F3 | -0.0444555 |
| FLNB | filamin B, beta | -0.0441099 |
| FOSB | FBJ murine osteosarcoma viral oncogene homolog B | -0.0435954 |
| APLP2 | amyloid beta (A4) precursor-like protein 2 | -0.0433882 |
| LOXL2 | lysyl oxidase-like 2 | -0.0433254 |
| ACTG1 | actin gamma 1 | -0.0432227 |
| RBPJ | recombination signal binding protein for immunoglobulin kappa J region | -0.0424978 |
| ARHGAP35 | Rho GTPase activating protein 35 | -0.0420361 |
| PLIN2 | perilipin 2 | -0.0415652 |
| POTEF | POTE ankyrin domain family, member F | -0.0412565 |
| SYT1 | synaptotagmin I | -0.0408689 |
| ATP2B1 | ATPase, Ca++ transporting, plasma membrane 1 | -0.0404479 |
| SOD2 | superoxide dismutase 2, mitochondrial | -0.0402117 |
| APBB2 | amyloid beta (A4) precursor protein-binding, family B, member 2 | -0.0398962 |
| ERO1B | endoplasmic reticulum oxidoreductase 1 beta | -0.0397966 |
| HNRNPU | heterogeneous nuclear ribonucleoprotein U (scaffold attachment factor A) | -0.0397264 |
| AGAP1 | ArfGAP with GTPase domain, ankyrin repeat and PH domain 1 | -0.0391461 |
| SPDYA | speedy/RINGO cell cycle regulator family member A | -0.0383547 |
| CDH11 | cadherin 11, type 2, OB-cadherin (osteoblast) | -0.0383116 |
| MYOF | myoferlin | -0.0382463 |
| RASAL2 | RAS protein activator like 2 | -0.0376305 |
| LRRC23 | leucine rich repeat containing 23 | -0.0367103 |
| LMNA | lamin A/C | -0.0366751 |
| PRKCA | protein kinase C, alpha | -0.0363677 |
| CXCL8 | chemokine (C-X-C motif) ligand 8 | -0.0362166 |
| GPC6 | glypican 6 | -0.0354915 |
| PDLIM5 | PDZ and LIM domain 5 | -0.0354779 |
| ASPH | aspartate beta-hydroxylase | -0.0353522 |
| HIVEP2 | human immunodeficiency virus type I enhancer binding protein 2 | -0.034984 |
| TUFT1 | tuftelin 1 | -0.0344734 |
| HNRNPA2B1 | heterogeneous nuclear ribonucleoprotein A2/B1 | -0.034356 |
| SPAG9 | sperm associated antigen 9 | -0.0341754 |
| MGAT5 | mannosyl (alpha-1,6-)-glycoprotein beta-1,6-N-acetyl-glucosaminyltransferase | -0.0340609 |
| GFPT1 | glutamine--fructose-6-phosphate transaminase 1 | -0.0339439 |
| ERO1A | endoplasmic reticulum oxidoreductase 1 alpha | -0.0338539 |
| SHC3 | SHC (Src homology 2 domain containing) transforming protein 3 | -0.0338373 |
| FMNL2 | formin-like 2 | -0.0336301 |
| FOS | FBJ murine osteosarcoma viral oncogene homolog | -0.0332369 |
| YWHAZ | tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, zeta | -0.0327477 |
| PALLD | palladin, cytoskeletal associated protein | -0.0325892 |
| TNS3 | tensin 3 | -0.0320746 |
| HSP90AA1 | heat shock protein 90kDa alpha (cytosolic), class A member 1 | -0.0312035 |
| HDLBP | high density lipoprotein binding protein | -0.0309826 |
| TBC1D8 | TBC1 domain family, member 8 (with GRAM domain) | -0.0306174 |
| PTK2 | protein tyrosine kinase 2 | -0.0305157 |
| ENO2 | enolase 2 (gamma, neuronal) | -0.0302468 |
| IFRD1 | interferon-related developmental regulator 1 | -0.0301659 |
| ENO1 | enolase 1, (alpha) | -0.0299117 |
| SFTPA2 | surfactant protein A2 | -0.029764 |
| MBNL1 | muscleblind-like splicing regulator 1 | -0.0295104 |
| ADIPOR2 | adiponectin receptor 2 | -0.0292143 |
| HILPDA | hypoxia inducible lipid droplet-associated | -0.0291982 |
| KCNQ5 | potassium channel, voltage gated KQT-like subfamily Q, member 5 | -0.0291387 |
| SOX5 | SRY (sex determining region Y)-box 5 | -0.0288821 |
| TBC1D22A | TBC1 domain family, member 22A | -0.0288058 |
| RYBP | RING1 and YY1 binding protein | -0.0286081 |
| SPTBN1 | spectrin, beta, non-erythrocytic 1 | -0.0283655 |
| CD109 | CD109 molecule | -0.0280374 |
| AGO2 | argonaute RISC catalytic component 2 | -0.0274354 |
| GLUL | glutamate-ammonia ligase | -0.0273993 |
| HELZ | helicase with zinc finger | -0.0273687 |
| RAD51B | RAD51 paralog B | -0.0271212 |
| RUNX1 | runt-related transcription factor 1 | -0.0269352 |
| BICD1 | bicaudal D homolog 1 (Drosophila) | -0.0268483 |
| EMP1 | epithelial membrane protein 1 | -0.0267522 |
| SCD | stearoyl-CoA desaturase (delta-9-desaturase) | -0.0265632 |
| PDE4D | phosphodiesterase 4D, cAMP-specific | -0.0264482 |
| RNF213 | ring finger protein 213 | -0.0263073 |
| COPA | coatomer protein complex, subunit alpha | -0.0257892 |
