| Dataset | Tahoe Therapeutics Tahoe 100M Perturbation Atlas |
| Category | transcriptomics |
| Type | cell type |
| Description | Esmolol (hydrochloride) perturbation in AN3 CA cell line (Tahoe Therapeutics) |
| Similar Terms | |
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200 genes differentially expressed following the Esmolol (hydrochloride)_AN3 CA drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| MEST | mesoderm specific transcript | 0.26555 |
| PRKG1 | protein kinase, cGMP-dependent, type I | 0.220122 |
| CADM2 | cell adhesion molecule 2 | 0.209959 |
| HMGA2 | high mobility group AT-hook 2 | 0.104136 |
| B3GALT1 | UDP-Gal:betaGlcNAc beta 1,3-galactosyltransferase, polypeptide 1 | 0.100681 |
| TPK1 | thiamin pyrophosphokinase 1 | 0.09576 |
| IMMP2L | IMP2 inner mitochondrial membrane peptidase-like (S. cerevisiae) | 0.0953518 |
| GAPDH | glyceraldehyde-3-phosphate dehydrogenase | 0.0920239 |
| FGFR1 | fibroblast growth factor receptor 1 | 0.0889767 |
| COL1A2 | collagen, type I, alpha 2 | 0.0862599 |
| PDE4D | phosphodiesterase 4D, cAMP-specific | 0.0848799 |
| TSHZ2 | teashirt zinc finger homeobox 2 | 0.0727114 |
| FNDC3B | fibronectin type III domain containing 3B | 0.0692907 |
| MGP | matrix Gla protein | 0.0683345 |
| PABPC1 | poly(A) binding protein, cytoplasmic 1 | 0.0649197 |
| LPP | LIM domain containing preferred translocation partner in lipoma | 0.0616151 |
| THSD4 | thrombospondin, type I, domain containing 4 | 0.0596654 |
| TRIO | trio Rho guanine nucleotide exchange factor | 0.0586849 |
| KAZN | kazrin, periplakin interacting protein | 0.0563134 |
| EGFR | epidermal growth factor receptor | 0.054808 |
| ACTG1 | actin gamma 1 | 0.0539467 |
| VIM | vimentin | 0.0528456 |
| SRRM2 | serine/arginine repetitive matrix 2 | 0.0488143 |
| FAM13A | family with sequence similarity 13, member A | 0.0470198 |
| TEAD1 | TEA domain family member 1 (SV40 transcriptional enhancer factor) | 0.046521 |
| EGR1 | early growth response 1 | 0.045614 |
| HSP90AA1 | heat shock protein 90kDa alpha (cytosolic), class A member 1 | 0.0433104 |
| RAD51B | RAD51 paralog B | 0.0424995 |
| PHF14 | PHD finger protein 14 | 0.0422286 |
| AGAP1 | ArfGAP with GTPase domain, ankyrin repeat and PH domain 1 | 0.0403459 |
| GNB1 | guanine nucleotide binding protein (G protein), beta polypeptide 1 | 0.039765 |
| RNF130 | ring finger protein 130 | 0.0392554 |
| GBE1 | glucan (1,4-alpha-), branching enzyme 1 | 0.0389583 |
| CALD1 | caldesmon 1 | 0.0371436 |
| PGK1 | phosphoglycerate kinase 1 | 0.0364046 |
| ZFHX3 | zinc finger homeobox 3 | 0.0360374 |
| MEOX2 | mesenchyme homeobox 2 | 0.0359791 |
| PTK2 | protein tyrosine kinase 2 | 0.0358936 |
| ERC1 | ELKS/RAB6-interacting/CAST family member 1 | 0.03577 |
| AKAP12 | A kinase (PRKA) anchor protein 12 | 0.0356008 |
| FLNA | filamin A, alpha | 0.035446 |
| SCD | stearoyl-CoA desaturase (delta-9-desaturase) | 0.0354435 |
| NFIB | nuclear factor I/B | 0.0350539 |
| ANKRD11 | ankyrin repeat domain 11 | 0.0350334 |
| FMNL2 | formin-like 2 | 0.0349703 |
| KMT2C | lysine (K)-specific methyltransferase 2C | 0.0348483 |
| BAZ1B | bromodomain adjacent to zinc finger domain, 1B | 0.0345744 |
| EXOC4 | exocyst complex component 4 | 0.0336008 |
| MBD5 | methyl-CpG binding domain protein 5 | 0.0333309 |
| KDM5B | lysine (K)-specific demethylase 5B | 0.033302 |
| SOX4 | SRY (sex determining region Y)-box 4 | 0.0332041 |
| NBEA | neurobeachin | 0.0330937 |
| RABGEF1 | RAB guanine nucleotide exchange factor (GEF) 1 | 0.0330804 |
| KDM4C | lysine (K)-specific demethylase 4C | 0.0316451 |
| PEG10 | paternally expressed 10 | 0.0313976 |
| TRERF1 | transcriptional regulating factor 1 | 0.0310773 |
| NFAT5 | nuclear factor of activated T-cells 5, tonicity-responsive | 0.0310222 |
| PCBP2 | poly(rC) binding protein 2 | 0.0308005 |
| PLS3 | plastin 3 | 0.0304812 |
| TBL1X | transducin (beta)-like 1X-linked | 0.0303141 |
| APLP2 | amyloid beta (A4) precursor-like protein 2 | 0.030241 |
| TULP4 | tubby like protein 4 | 0.0302027 |
| YWHAE | tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, epsilon | 0.0301254 |
| SOBP | sine oculis binding protein homolog (Drosophila) | 0.0300971 |
| ENO1 | enolase 1, (alpha) | 0.0299245 |
| FCHSD2 | FCH and double SH3 domains 2 | 0.0298039 |
| NFIA | nuclear factor I/A | 0.0293586 |
| RPS6 | ribosomal protein S6 | 0.028844 |
| H1-0 | H1.0 linker histone | 0.0287839 |
| CHD9 | chromodomain helicase DNA binding protein 9 | 0.0287619 |
| HDAC8 | histone deacetylase 8 | 0.0287192 |
| MTUS1 | microtubule associated tumor suppressor 1 | 0.0284269 |
| SSH2 | slingshot protein phosphatase 2 | 0.0276531 |
| ARIH1 | ariadne RBR E3 ubiquitin protein ligase 1 | 0.0274902 |
| CSDE1 | cold shock domain containing E1, RNA-binding | 0.0274418 |
| SHROOM3 | shroom family member 3 | 0.0268707 |
| FARP1 | FERM, RhoGEF (ARHGEF) and pleckstrin domain protein 1 (chondrocyte-derived) | 0.0266711 |
| ASAP1 | ArfGAP with SH3 domain, ankyrin repeat and PH domain 1 | 0.0263374 |
| REV3L | REV3-like, polymerase (DNA directed), zeta, catalytic subunit | 0.0261668 |
| ARID1A | AT rich interactive domain 1A (SWI-like) | 0.0257402 |
| PITPNC1 | phosphatidylinositol transfer protein, cytoplasmic 1 | 0.0256971 |
| GMDS | GDP-mannose 4,6-dehydratase | 0.025556 |
| DHX9 | DEAH (Asp-Glu-Ala-His) box helicase 9 | 0.0254621 |
| PRKN | parkin RBR E3 ubiquitin protein ligase | 0.0253536 |
| RNF216 | ring finger protein 216 | 0.0251496 |
| TUBB | tubulin, beta class I | 0.025112 |
| DLG1 | discs, large homolog 1 (Drosophila) | 0.0250395 |
| MAP1B | microtubule-associated protein 1B | 0.0249921 |
| AGO2 | argonaute RISC catalytic component 2 | 0.0249256 |
| CSNK1A1 | casein kinase 1, alpha 1 | 0.0248597 |
| MSRA | methionine sulfoxide reductase A | 0.0248507 |
| FTH1 | ferritin, heavy polypeptide 1 | 0.0243508 |
| ADNP | activity-dependent neuroprotector homeobox | 0.024223 |
| MACF1 | microtubule-actin crosslinking factor 1 | 0.0239401 |
| INO80 | INO80 complex subunit | 0.0238831 |
| RC3H1 | ring finger and CCCH-type domains 1 | 0.0238492 |
| PCM1 | pericentriolar material 1 | 0.0236691 |
| PRRC2A | proline-rich coiled-coil 2A | 0.0234457 |
| VTI1A | vesicle transport through interaction with t-SNAREs 1A | 0.0233879 |
| EFNA5 | ephrin-A5 | 0.0233671 |
| Symbol | Name | Standardized Value |
|---|---|---|
| HNRNPU | heterogeneous nuclear ribonucleoprotein U (scaffold attachment factor A) | -0.0786674 |
| NPM1 | nucleophosmin (nucleolar phosphoprotein B23, numatrin) | -0.0781106 |
| MATR3 | matrin 3 | -0.0730033 |
| ZEB1 | zinc finger E-box binding homeobox 1 | -0.0662237 |
| HMGB2 | high mobility group box 2 | -0.052835 |
| PTMA | prothymosin, alpha | -0.0528277 |
| ERO1A | endoplasmic reticulum oxidoreductase 1 alpha | -0.0472047 |
| NIPBL | Nipped-B homolog (Drosophila) | -0.0441908 |
| NUCKS1 | nuclear casein kinase and cyclin-dependent kinase substrate 1 | -0.0433862 |
| TOP2B | topoisomerase (DNA) II beta 180kDa | -0.0430569 |
| H1-4 | H1.4 linker histone, cluster member | -0.0425636 |
| HNRNPA2B1 | heterogeneous nuclear ribonucleoprotein A2/B1 | -0.0421496 |
| CENPF | centromere protein F, 350/400kDa | -0.0406508 |
| CALM2 | calmodulin 2 (phosphorylase kinase, delta) | -0.0390274 |
| TOP2A | topoisomerase (DNA) II alpha 170kDa | -0.0377039 |
| RPS2 | ribosomal protein S2 | -0.0375386 |
| RPL38 | ribosomal protein L38 | -0.0375209 |
| SPAG9 | sperm associated antigen 9 | -0.0362385 |
| IRF2BP2 | interferon regulatory factor 2 binding protein 2 | -0.035832 |
| FXR1 | fragile X mental retardation, autosomal homolog 1 | -0.0351685 |
| GAS2L3 | growth arrest-specific 2 like 3 | -0.0344145 |
| TMSB4X | thymosin beta 4, X-linked | -0.0332143 |
| RPS24 | ribosomal protein S24 | -0.0325503 |
| ANLN | anillin, actin binding protein | -0.0323744 |
| VPS26A | vacuolar protein sorting 26 homolog A (S. pombe) | -0.0322171 |
| NAMPT | nicotinamide phosphoribosyltransferase | -0.0319465 |
| TBL1XR1 | transducin (beta)-like 1 X-linked receptor 1 | -0.0317768 |
| RPL7 | ribosomal protein L7 | -0.0313515 |
| MED13L | mediator complex subunit 13-like | -0.0304289 |
| UBR2 | ubiquitin protein ligase E3 component n-recognin 2 | -0.0303944 |
| IGF2 | insulin-like growth factor 2 | -0.0301816 |
| MT2A | metallothionein 2A | -0.0296256 |
| RPS25 | ribosomal protein S25 | -0.02962 |
| CKAP2 | cytoskeleton associated protein 2 | -0.0284859 |
| DNAJC1 | DnaJ (Hsp40) homolog, subfamily C, member 1 | -0.0281311 |
| TPX2 | TPX2, microtubule-associated | -0.0273672 |
| ZNF292 | zinc finger protein 292 | -0.0271343 |
| HNRNPK | heterogeneous nuclear ribonucleoprotein K | -0.0266111 |
| XPO1 | exportin 1 | -0.0263994 |
| MALSU1 | mitochondrial assembly of ribosomal large subunit 1 | -0.0261953 |
| DLGAP5 | discs, large (Drosophila) homolog-associated protein 5 | -0.0261491 |
| RLF | rearranged L-myc fusion | -0.0258435 |
| RPL17-C18ORF32 | RPL17-C18orf32 readthrough | -0.0257403 |
| USP3 | ubiquitin specific peptidase 3 | -0.0255771 |
| SMG1 | SMG1 phosphatidylinositol 3-kinase-related kinase | -0.0248289 |
| DYRK1A | dual-specificity tyrosine-(Y)-phosphorylation regulated kinase 1A | -0.0246624 |
| RPS18 | ribosomal protein S18 | -0.024385 |
| RPS23 | ribosomal protein S23 | -0.0242399 |
| ITGAV | integrin, alpha V | -0.024211 |
| HSPA9 | heat shock 70kDa protein 9 (mortalin) | -0.0240973 |
| KMT2E | lysine (K)-specific methyltransferase 2E | -0.0235189 |
| HIF1A | hypoxia inducible factor 1, alpha subunit (basic helix-loop-helix transcription factor) | -0.0233699 |
| PARP14 | poly (ADP-ribose) polymerase family, member 14 | -0.0233329 |
| PELI1 | pellino E3 ubiquitin protein ligase 1 | -0.0230377 |
| EEF1A1 | eukaryotic translation elongation factor 1 alpha 1 | -0.0225956 |
| USP13 | ubiquitin specific peptidase 13 (isopeptidase T-3) | -0.0225835 |
| NCAPG | non-SMC condensin I complex, subunit G | -0.022397 |
| SQSTM1 | sequestosome 1 | -0.0223005 |
| OGA | O-GlcNAcase | -0.0222047 |
| KIAA1958 | KIAA1958 | -0.0221274 |
| RHEB | Ras homolog enriched in brain | -0.0218976 |
| MRTFA | myocardin related transcription factor A | -0.0218166 |
| PDE4B | phosphodiesterase 4B, cAMP-specific | -0.0217678 |
| PRRC2C | proline-rich coiled-coil 2C | -0.0214061 |
| PTP4A2 | protein tyrosine phosphatase type IVA, member 2 | -0.0213954 |
| CCNB1 | cyclin B1 | -0.0212599 |
| NAP1L4 | nucleosome assembly protein 1-like 4 | -0.021017 |
| CAMTA1 | calmodulin binding transcription activator 1 | -0.020841 |
| EIF4G2 | eukaryotic translation initiation factor 4 gamma, 2 | -0.0206678 |
| NNT | nicotinamide nucleotide transhydrogenase | -0.0205511 |
| NFATC3 | nuclear factor of activated T-cells, cytoplasmic, calcineurin-dependent 3 | -0.0204606 |
| CCT5 | chaperonin containing TCP1, subunit 5 (epsilon) | -0.0203688 |
| HOXA3 | homeobox A3 | -0.0203465 |
| SNX3 | sorting nexin 3 | -0.0203365 |
| TMPO | thymopoietin | -0.0201982 |
| CCNG1 | cyclin G1 | -0.0201566 |
| SMAP1 | small ArfGAP 1 | -0.0199399 |
| TAOK1 | TAO kinase 1 | -0.0198489 |
| MYEF2 | myelin expression factor 2 | -0.019396 |
| TAB2 | TGF-beta activated kinase 1/MAP3K7 binding protein 2 | -0.0192132 |
| TM9SF3 | transmembrane 9 superfamily member 3 | -0.0190711 |
| VPS13C | vacuolar protein sorting 13 homolog C (S. cerevisiae) | -0.0189866 |
| NAV2 | neuron navigator 2 | -0.0188294 |
| AGPAT5 | 1-acylglycerol-3-phosphate O-acyltransferase 5 | -0.0188147 |
| ACSL3 | acyl-CoA synthetase long-chain family member 3 | -0.0187847 |
| TAF15 | TAF15 RNA polymerase II, TATA box binding protein (TBP)-associated factor, 68kDa | -0.0184711 |
| H1-2 | H1.2 linker histone, cluster member | -0.0183493 |
| FBL | fibrillarin | -0.0182844 |
| NAP1L1 | nucleosome assembly protein 1-like 1 | -0.0179516 |
| RACGAP1 | Rac GTPase activating protein 1 | -0.017951 |
| PARK7 | parkinson protein 7 | -0.017862 |
| PNRC1 | proline-rich nuclear receptor coactivator 1 | -0.0176105 |
| ARHGAP11A | Rho GTPase activating protein 11A | -0.017464 |
| CLTC | clathrin, heavy chain (Hc) | -0.017399 |
| RPL6 | ribosomal protein L6 | -0.0173244 |
| RPL34 | ribosomal protein L34 | -0.0172831 |
| CCNC | cyclin C | -0.0172737 |
| ERBIN | erbb2 interacting protein | -0.0172441 |
| FAM222B | family with sequence similarity 222, member B | -0.017173 |
| BUB3 | BUB3 mitotic checkpoint protein | -0.0171688 |
