| Dataset | Tahoe Therapeutics Tahoe 100M Perturbation Atlas |
| Category | transcriptomics |
| Type | cell type |
| Description | Esmolol (hydrochloride) perturbation in AsPC-1 cell line (Tahoe Therapeutics) |
| Similar Terms | |
| Downloads & Tools |
200 genes differentially expressed following the Esmolol (hydrochloride)_AsPC-1 drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| AKAP12 | A kinase (PRKA) anchor protein 12 | 0.274849 |
| EGFR | epidermal growth factor receptor | 0.179751 |
| LAMA4 | laminin, alpha 4 | 0.148606 |
| FLNB | filamin B, beta | 0.132983 |
| PSD3 | pleckstrin and Sec7 domain containing 3 | 0.132156 |
| VCAN | versican | 0.118159 |
| GAPDH | glyceraldehyde-3-phosphate dehydrogenase | 0.117943 |
| SLC38A2 | solute carrier family 38, member 2 | 0.110597 |
| GPRC5A | G protein-coupled receptor, class C, group 5, member A | 0.106466 |
| ITGA6 | integrin, alpha 6 | 0.103409 |
| MYOF | myoferlin | 0.10013 |
| ARHGAP42 | Rho GTPase activating protein 42 | 0.0977062 |
| MUC17 | mucin 17, cell surface associated | 0.0944184 |
| ITPRID2 | ITPR interacting domain containing 2 | 0.0927071 |
| VCL | vinculin | 0.0890288 |
| DOCK5 | dedicator of cytokinesis 5 | 0.0845412 |
| PTPRR | protein tyrosine phosphatase, receptor type, R | 0.0828763 |
| LMO7 | LIM domain 7 | 0.081337 |
| FNDC3B | fibronectin type III domain containing 3B | 0.0796369 |
| KCNK1 | potassium channel, two pore domain subfamily K, member 1 | 0.0747575 |
| UACA | uveal autoantigen with coiled-coil domains and ankyrin repeats | 0.0720749 |
| NFAT5 | nuclear factor of activated T-cells 5, tonicity-responsive | 0.0696994 |
| ARPC1B | actin related protein 2/3 complex, subunit 1B, 41kDa | 0.0677232 |
| BCL2L1 | BCL2-like 1 | 0.0657279 |
| PRELID2 | PRELI domain containing 2 | 0.0646736 |
| EZR | ezrin | 0.0645059 |
| VIM | vimentin | 0.0636617 |
| FOXO1 | forkhead box O1 | 0.062361 |
| EFNA5 | ephrin-A5 | 0.0620832 |
| NDRG1 | N-myc downstream regulated 1 | 0.0617026 |
| PABPC1 | poly(A) binding protein, cytoplasmic 1 | 0.0616798 |
| NPSR1 | neuropeptide S receptor 1 | 0.0616341 |
| ITGA2 | integrin, alpha 2 (CD49B, alpha 2 subunit of VLA-2 receptor) | 0.0600297 |
| ATP2B4 | ATPase, Ca++ transporting, plasma membrane 4 | 0.0598368 |
| ITGB4 | integrin, beta 4 | 0.0593913 |
| ERBIN | erbb2 interacting protein | 0.0590667 |
| AHNAK | AHNAK nucleoprotein | 0.0590605 |
| S100A10 | S100 calcium binding protein A10 | 0.0586872 |
| LDHA | lactate dehydrogenase A | 0.0581319 |
| AKAP13 | A kinase (PRKA) anchor protein 13 | 0.0581158 |
| EMP1 | epithelial membrane protein 1 | 0.0580677 |
| SMAD3 | SMAD family member 3 | 0.0568286 |
| ANXA11 | annexin A11 | 0.0568118 |
| LOC112694756 | uncharaterized LOC112694756 | 0.0536126 |
| SDC4 | syndecan 4 | 0.0535896 |
| TBC1D8 | TBC1 domain family, member 8 (with GRAM domain) | 0.0534184 |
| YWHAZ | tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, zeta | 0.0499084 |
| BAIAP2L1 | BAI1-associated protein 2-like 1 | 0.0497162 |
| DCBLD2 | discoidin, CUB and LCCL domain containing 2 | 0.0495424 |
| MPRIP | myosin phosphatase Rho interacting protein | 0.0492648 |
| WWC1 | WW and C2 domain containing 1 | 0.0488317 |
| ASPH | aspartate beta-hydroxylase | 0.0482802 |
| APLP2 | amyloid beta (A4) precursor-like protein 2 | 0.0479007 |
| JMJD1C | jumonji domain containing 1C | 0.0477113 |
| CORO1C | coronin, actin binding protein, 1C | 0.0473795 |
| MYO1E | myosin IE | 0.0467807 |
| SPTBN1 | spectrin, beta, non-erythrocytic 1 | 0.0466107 |
| MAML2 | mastermind-like 2 (Drosophila) | 0.0453217 |
| SRRM2 | serine/arginine repetitive matrix 2 | 0.0452258 |
| TRIO | trio Rho guanine nucleotide exchange factor | 0.0451126 |
| DPYSL2 | dihydropyrimidinase-like 2 | 0.0445371 |
| FAT1 | FAT atypical cadherin 1 | 0.0439049 |
| DDX60L | DEAD (Asp-Glu-Ala-Asp) box polypeptide 60-like | 0.0437149 |
| PITPNC1 | phosphatidylinositol transfer protein, cytoplasmic 1 | 0.0434666 |
| RASAL2 | RAS protein activator like 2 | 0.042935 |
| PDE4D | phosphodiesterase 4D, cAMP-specific | 0.0428006 |
| CD59 | CD59 molecule, complement regulatory protein | 0.042327 |
| MYH9 | myosin, heavy chain 9, non-muscle | 0.0419702 |
| ESYT2 | extended synaptotagmin-like protein 2 | 0.0417277 |
| ZBTB20 | zinc finger and BTB domain containing 20 | 0.0415677 |
| DSPP | dentin sialophosphoprotein | 0.0415627 |
| HMGA2 | high mobility group AT-hook 2 | 0.0415609 |
| POTEF | POTE ankyrin domain family, member F | 0.0415196 |
| SEPTIN9 | septin 9 | 0.0411752 |
| EHBP1 | EH domain binding protein 1 | 0.0409979 |
| TSC22D2 | TSC22 domain family, member 2 | 0.0404194 |
| COL17A1 | collagen, type XVII, alpha 1 | 0.0402926 |
| ACTN4 | actinin, alpha 4 | 0.039972 |
| SLC2A1 | solute carrier family 2 (facilitated glucose transporter), member 1 | 0.0397868 |
| ARHGAP29 | Rho GTPase activating protein 29 | 0.039683 |
| RABGAP1L | RAB GTPase activating protein 1-like | 0.0396329 |
| CDH17 | cadherin 17, LI cadherin (liver-intestine) | 0.0394019 |
| STK39 | serine threonine kinase 39 | 0.0392802 |
| CLIP2 | CAP-GLY domain containing linker protein 2 | 0.0392733 |
| ROCK2 | Rho-associated, coiled-coil containing protein kinase 2 | 0.038852 |
| SLC20A1 | solute carrier family 20 (phosphate transporter), member 1 | 0.0385459 |
| CEACAM1 | carcinoembryonic antigen-related cell adhesion molecule 1 (biliary glycoprotein) | 0.0385117 |
| UBE2H | ubiquitin-conjugating enzyme E2H | 0.0381356 |
| RAPH1 | Ras association (RalGDS/AF-6) and pleckstrin homology domains 1 | 0.037118 |
| IGFBP3 | insulin-like growth factor binding protein 3 | 0.0369559 |
| SEMA3C | sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3C | 0.0367869 |
| RCOR1 | REST corepressor 1 | 0.0365255 |
| PLEKHA1 | pleckstrin homology domain containing, family A (phosphoinositide binding specific) member 1 | 0.0363562 |
| TGM2 | transglutaminase 2 | 0.0363321 |
| B4GALT5 | UDP-Gal:betaGlcNAc beta 1,4- galactosyltransferase, polypeptide 5 | 0.0362066 |
| TMEM164 | transmembrane protein 164 | 0.0361053 |
| CD9 | CD9 molecule | 0.0358307 |
| DSG2 | desmoglein 2 | 0.0358171 |
| PHLDA1 | pleckstrin homology-like domain, family A, member 1 | 0.0358022 |
| PALM2AKAP2 | PALM2 and AKAP2 fusion | 0.0357331 |
| Symbol | Name | Standardized Value |
|---|---|---|
| LAMB3 | laminin, beta 3 | -0.133833 |
| DHRS9 | dehydrogenase/reductase (SDR family) member 9 | -0.121869 |
| TPT1 | tumor protein, translationally-controlled 1 | -0.0755949 |
| CALM2 | calmodulin 2 (phosphorylase kinase, delta) | -0.0623071 |
| HSPA5 | heat shock 70kDa protein 5 (glucose-regulated protein, 78kDa) | -0.0614396 |
| ARPC1A | actin related protein 2/3 complex, subunit 1A, 41kDa | -0.0388718 |
| TMSB10 | thymosin beta 10 | -0.0380247 |
| HSPH1 | heat shock 105kDa/110kDa protein 1 | -0.0374956 |
| MAP4K4 | mitogen-activated protein kinase kinase kinase kinase 4 | -0.0362941 |
| SMURF1 | SMAD specific E3 ubiquitin protein ligase 1 | -0.0330173 |
| DNAJA1 | DnaJ (Hsp40) homolog, subfamily A, member 1 | -0.0319925 |
| HNRNPU | heterogeneous nuclear ribonucleoprotein U (scaffold attachment factor A) | -0.0308361 |
| HSP90AA1 | heat shock protein 90kDa alpha (cytosolic), class A member 1 | -0.0293171 |
| GBE1 | glucan (1,4-alpha-), branching enzyme 1 | -0.0289597 |
| LMTK2 | lemur tyrosine kinase 2 | -0.0275142 |
| UPP1 | uridine phosphorylase 1 | -0.0272112 |
| CLMP | CXADR-like membrane protein | -0.0265256 |
| RAB1A | RAB1A, member RAS oncogene family | -0.0261072 |
| ABTB3 | ankyrin repeat and BTB domain containing 3 | -0.0249355 |
| PMM2 | phosphomannomutase 2 | -0.0246702 |
| EIF3H | eukaryotic translation initiation factor 3, subunit H | -0.0245007 |
| MXD1 | MAX dimerization protein 1 | -0.0242167 |
| FTL | ferritin, light polypeptide | -0.0240796 |
| KLK10 | kallikrein-related peptidase 10 | -0.0238187 |
| PARD3 | par-3 family cell polarity regulator | -0.0231651 |
| MORF4L2 | mortality factor 4 like 2 | -0.022347 |
| CAP1 | CAP, adenylate cyclase-associated protein 1 (yeast) | -0.022345 |
| INTS6 | integrator complex subunit 6 | -0.0217415 |
| ABHD3 | abhydrolase domain containing 3 | -0.0213769 |
| TRA2A | transformer 2 alpha homolog (Drosophila) | -0.0205075 |
| PPARD | peroxisome proliferator-activated receptor delta | -0.0200241 |
| CLINT1 | clathrin interactor 1 | -0.0199237 |
| RPS24 | ribosomal protein S24 | -0.0196824 |
| KDM3A | lysine (K)-specific demethylase 3A | -0.0195556 |
| BMP6 | bone morphogenetic protein 6 | -0.019494 |
| FUT8 | fucosyltransferase 8 (alpha (1,6) fucosyltransferase) | -0.019476 |
| HSP90B1 | heat shock protein 90kDa beta (Grp94), member 1 | -0.0186467 |
| ZSWIM6 | zinc finger, SWIM-type containing 6 | -0.0186205 |
| BLZF1 | basic leucine zipper nuclear factor 1 | -0.018487 |
| FMNL2 | formin-like 2 | -0.0183504 |
| RAB7A | RAB7A, member RAS oncogene family | -0.0181843 |
| MBOAT2 | membrane bound O-acyltransferase domain containing 2 | -0.0178094 |
| HM13 | histocompatibility (minor) 13 | -0.0176292 |
| NOP58 | NOP58 ribonucleoprotein | -0.017561 |
| SIPA1L1 | signal-induced proliferation-associated 1 like 1 | -0.0175362 |
| KLF5 | Kruppel-like factor 5 (intestinal) | -0.0175181 |
| SENP5 | SUMO1/sentrin specific peptidase 5 | -0.0174528 |
| FXR1 | fragile X mental retardation, autosomal homolog 1 | -0.0171328 |
| WSB1 | WD repeat and SOCS box containing 1 | -0.0170208 |
| USP34 | ubiquitin specific peptidase 34 | -0.0169779 |
| RLF | rearranged L-myc fusion | -0.0166891 |
| SUCO | SUN domain containing ossification factor | -0.0163786 |
| THBD | thrombomodulin | -0.016274 |
| ZNF83 | zinc finger protein 83 | -0.0162489 |
| MARK3 | MAP/microtubule affinity-regulating kinase 3 | -0.0161518 |
| RAB2A | RAB2A, member RAS oncogene family | -0.015943 |
| MARCHF6 | membrane associated ring-CH-type finger 6 | -0.0158494 |
| HSPA9 | heat shock 70kDa protein 9 (mortalin) | -0.0156607 |
| SEC31A | SEC31 homolog A (S. cerevisiae) | -0.0154759 |
| RPL35A | ribosomal protein L35a | -0.0152174 |
| EIF3A | eukaryotic translation initiation factor 3, subunit A | -0.0152035 |
| PSMD14 | proteasome (prosome, macropain) 26S subunit, non-ATPase, 14 | -0.0150649 |
| UBAP2 | ubiquitin associated protein 2 | -0.0148068 |
| MON2 | MON2 homolog (S. cerevisiae) | -0.0146266 |
| DIS3 | DIS3 exosome endoribonuclease and 3'-5' exoribonuclease | -0.0144839 |
| EXT1 | exostosin glycosyltransferase 1 | -0.0144281 |
| MYSM1 | Myb-like, SWIRM and MPN domains 1 | -0.0142727 |
| BTAF1 | BTAF1 RNA polymerase II, B-TFIID transcription factor-associated, 170kDa | -0.0141633 |
| CANX | calnexin | -0.0139404 |
| GNAS | GNAS complex locus | -0.0139314 |
| CAMK1D | calcium/calmodulin-dependent protein kinase ID | -0.0139205 |
| PNPLA8 | patatin-like phospholipase domain containing 8 | -0.0138545 |
| GFPT1 | glutamine--fructose-6-phosphate transaminase 1 | -0.0137607 |
| NOLC1 | nucleolar and coiled-body phosphoprotein 1 | -0.0137472 |
| COPB2 | coatomer protein complex, subunit beta 2 (beta prime) | -0.0137338 |
| SPDYA | speedy/RINGO cell cycle regulator family member A | -0.0137267 |
| ZHX2 | zinc fingers and homeoboxes 2 | -0.0136576 |
| COG5 | component of oligomeric golgi complex 5 | -0.0136035 |
| SLC9A3R2 | solute carrier family 9, subfamily A (NHE3, cation proton antiporter 3), member 3 regulator 2 | -0.0135599 |
| TM9SF3 | transmembrane 9 superfamily member 3 | -0.0135513 |
| NAP1L4 | nucleosome assembly protein 1-like 4 | -0.013492 |
| MCU | mitochondrial calcium uniporter | -0.0132589 |
| IER3 | immediate early response 3 | -0.0131345 |
| NAMPT | nicotinamide phosphoribosyltransferase | -0.0129247 |
| TMEM106B | transmembrane protein 106B | -0.0129195 |
| SMNDC1 | survival motor neuron domain containing 1 | -0.0127093 |
| TBC1D15 | TBC1 domain family, member 15 | -0.012691 |
| ARHGEF10 | Rho guanine nucleotide exchange factor (GEF) 10 | -0.0126791 |
| PJA2 | praja ring finger 2, E3 ubiquitin protein ligase | -0.0126451 |
| AK1 | adenylate kinase 1 | -0.0125756 |
| VRK2 | vaccinia related kinase 2 | -0.0125653 |
| DNAJC3 | DnaJ (Hsp40) homolog, subfamily C, member 3 | -0.0125458 |
| STC1 | stanniocalcin 1 | -0.0125068 |
| TXNRD1 | thioredoxin reductase 1 | -0.0124842 |
| CD164 | CD164 molecule, sialomucin | -0.0123534 |
| STIP1 | stress-induced phosphoprotein 1 | -0.0123521 |
| COPA | coatomer protein complex, subunit alpha | -0.0122958 |
| FGFR1 | fibroblast growth factor receptor 1 | -0.0121345 |
| TAX1BP1 | Tax1 (human T-cell leukemia virus type I) binding protein 1 | -0.0121243 |
| RIOK3 | RIO kinase 3 | -0.0120441 |
