| Dataset | Tahoe Therapeutics Tahoe 100M Perturbation Atlas |
| Category | transcriptomics |
| Type | cell type |
| Description | Esmolol (hydrochloride) perturbation in C-33 A cell line (Tahoe Therapeutics) |
| Similar Terms | |
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200 genes differentially expressed following the Esmolol (hydrochloride)_C-33 A drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| SLIT2 | slit homolog 2 (Drosophila) | 0.227937 |
| TENM3 | teneurin transmembrane protein 3 | 0.194072 |
| NEBL | nebulette | 0.135498 |
| RAD51B | RAD51 paralog B | 0.129287 |
| ZNF608 | zinc finger protein 608 | 0.119694 |
| COL5A2 | collagen, type V, alpha 2 | 0.0977001 |
| ERBB4 | erb-b2 receptor tyrosine kinase 4 | 0.0823254 |
| GBE1 | glucan (1,4-alpha-), branching enzyme 1 | 0.0780721 |
| TOX | thymocyte selection-associated high mobility group box | 0.0637798 |
| HSP90B1 | heat shock protein 90kDa beta (Grp94), member 1 | 0.0628582 |
| TTC28 | tetratricopeptide repeat domain 28 | 0.0606396 |
| SCD | stearoyl-CoA desaturase (delta-9-desaturase) | 0.060575 |
| NR5A2 | nuclear receptor subfamily 5, group A, member 2 | 0.0578285 |
| IMMP2L | IMP2 inner mitochondrial membrane peptidase-like (S. cerevisiae) | 0.0541979 |
| WSB1 | WD repeat and SOCS box containing 1 | 0.0508262 |
| ATP11A | ATPase, class VI, type 11A | 0.0491738 |
| MLIP | muscular LMNA-interacting protein | 0.0488823 |
| SOX5 | SRY (sex determining region Y)-box 5 | 0.0486375 |
| SRRM2 | serine/arginine repetitive matrix 2 | 0.0472897 |
| SMYD3 | SET and MYND domain containing 3 | 0.046375 |
| CTNNA2 | catenin (cadherin-associated protein), alpha 2 | 0.0449465 |
| GYS1 | glycogen synthase 1 (muscle) | 0.0445485 |
| ERC1 | ELKS/RAB6-interacting/CAST family member 1 | 0.04416 |
| DST | dystonin | 0.0438756 |
| EEF2 | eukaryotic translation elongation factor 2 | 0.0433609 |
| RERE | arginine-glutamic acid dipeptide (RE) repeats | 0.0428641 |
| CABIN1 | calcineurin binding protein 1 | 0.0420578 |
| HELZ | helicase with zinc finger | 0.0418358 |
| HSP90AA1 | heat shock protein 90kDa alpha (cytosolic), class A member 1 | 0.0414729 |
| HSPA8 | heat shock 70kDa protein 8 | 0.0403033 |
| SET | SET nuclear proto-oncogene | 0.0390679 |
| OSBPL10 | oxysterol binding protein-like 10 | 0.0390167 |
| GNPDA1 | glucosamine-6-phosphate deaminase 1 | 0.0385137 |
| BNC2 | basonuclin 2 | 0.0382561 |
| PDE4D | phosphodiesterase 4D, cAMP-specific | 0.0376907 |
| PRICKLE1 | prickle homolog 1 (Drosophila) | 0.0375268 |
| FMNL2 | formin-like 2 | 0.0368935 |
| ARHGAP32 | Rho GTPase activating protein 32 | 0.036858 |
| KTN1 | kinectin 1 (kinesin receptor) | 0.0363842 |
| DENND1A | DENN/MADD domain containing 1A | 0.0362863 |
| RBFOX2 | RNA binding protein, fox-1 homolog (C. elegans) 2 | 0.0345846 |
| MCTP1 | multiple C2 domains, transmembrane 1 | 0.0341358 |
| TRIO | trio Rho guanine nucleotide exchange factor | 0.0335962 |
| FAT1 | FAT atypical cadherin 1 | 0.0332612 |
| VCL | vinculin | 0.0330513 |
| NR4A3 | nuclear receptor subfamily 4, group A, member 3 | 0.0329519 |
| UBR4 | ubiquitin protein ligase E3 component n-recognin 4 | 0.0328696 |
| MLLT10 | myeloid/lymphoid or mixed-lineage leukemia (trithorax homolog, Drosophila); translocated to, 10 | 0.0328073 |
| TBC1D32 | TBC1 domain family, member 32 | 0.0323517 |
| N4BP2L2 | NEDD4 binding protein 2-like 2 | 0.032338 |
| ANKS1B | ankyrin repeat and sterile alpha motif domain containing 1B | 0.0323036 |
| SBF2 | SET binding factor 2 | 0.032247 |
| ERO1A | endoplasmic reticulum oxidoreductase 1 alpha | 0.0318411 |
| P4HB | prolyl 4-hydroxylase, beta polypeptide | 0.0316183 |
| BACH2 | BTB and CNC homology 1, basic leucine zipper transcription factor 2 | 0.031224 |
| UBR5 | ubiquitin protein ligase E3 component n-recognin 5 | 0.0311577 |
| CCNY | cyclin Y | 0.0309889 |
| TEAD1 | TEA domain family member 1 (SV40 transcriptional enhancer factor) | 0.0303616 |
| ENO1 | enolase 1, (alpha) | 0.030234 |
| VMP1 | vacuole membrane protein 1 | 0.0301915 |
| BNIP3 | BCL2/adenovirus E1B 19kDa interacting protein 3 | 0.0301366 |
| PRRC2A | proline-rich coiled-coil 2A | 0.0299694 |
| WLS | wntless Wnt ligand secretion mediator | 0.0295775 |
| ACTG1 | actin gamma 1 | 0.0293609 |
| RNASE12 | ribonuclease, RNase A family, 12 (non-active) | 0.0286379 |
| HS2ST1 | heparan sulfate 2-O-sulfotransferase 1 | 0.0285343 |
| KIF1B | kinesin family member 1B | 0.0284893 |
| CUX1 | cut-like homeobox 1 | 0.0284283 |
| BCAS3 | breast carcinoma amplified sequence 3 | 0.0283748 |
| AGAP1 | ArfGAP with GTPase domain, ankyrin repeat and PH domain 1 | 0.0279683 |
| PABPC1 | poly(A) binding protein, cytoplasmic 1 | 0.0278946 |
| RPL11 | ribosomal protein L11 | 0.0276702 |
| APLP2 | amyloid beta (A4) precursor-like protein 2 | 0.0276225 |
| ADGRG6 | adhesion G protein-coupled receptor G6 | 0.027544 |
| FLNA | filamin A, alpha | 0.0272859 |
| CELF2 | CUGBP, Elav-like family member 2 | 0.0270876 |
| TTC3 | tetratricopeptide repeat domain 3 | 0.0270147 |
| PFKFB3 | 6-phosphofructo-2-kinase/fructose-2,6-biphosphatase 3 | 0.0268748 |
| RPL3 | ribosomal protein L3 | 0.0268134 |
| TANC2 | tetratricopeptide repeat, ankyrin repeat and coiled-coil containing 2 | 0.0267768 |
| FOXO3 | forkhead box O3 | 0.0266692 |
| GRID2 | glutamate receptor, ionotropic, delta 2 | 0.0266314 |
| MAPT | microtubule-associated protein tau | 0.0266089 |
| TBL1X | transducin (beta)-like 1X-linked | 0.0264465 |
| GAPDH | glyceraldehyde-3-phosphate dehydrogenase | 0.0264353 |
| RPTOR | regulatory associated protein of MTOR, complex 1 | 0.0263007 |
| HUWE1 | HECT, UBA and WWE domain containing 1, E3 ubiquitin protein ligase | 0.0262595 |
| ANKRD12 | ankyrin repeat domain 12 | 0.02595 |
| KIAA1958 | KIAA1958 | 0.0255872 |
| TOM1L2 | target of myb1-like 2 (chicken) | 0.0254984 |
| LENG8 | leukocyte receptor cluster (LRC) member 8 | 0.025471 |
| RPL28 | ribosomal protein L28 | 0.0253111 |
| RPS2 | ribosomal protein S2 | 0.0252558 |
| RAPGEF2 | Rap guanine nucleotide exchange factor (GEF) 2 | 0.0251803 |
| SUPT3H | suppressor of Ty 3 homolog (S. cerevisiae) | 0.0250349 |
| TNRC18 | trinucleotide repeat containing 18 | 0.0250183 |
| PHF3 | PHD finger protein 3 | 0.0248187 |
| DSCAM | Down syndrome cell adhesion molecule | 0.0244947 |
| ARB2A | ARB2 cotranscriptional regulator A | 0.0242673 |
| UBAP2 | ubiquitin associated protein 2 | 0.024222 |
| Symbol | Name | Standardized Value |
|---|---|---|
| TMSB10 | thymosin beta 10 | -0.0701267 |
| PTMA | prothymosin, alpha | -0.0580914 |
| KDM3A | lysine (K)-specific demethylase 3A | -0.0526728 |
| RPLP1 | ribosomal protein, large, P1 | -0.0475541 |
| RPL34 | ribosomal protein L34 | -0.040759 |
| RPS24 | ribosomal protein S24 | -0.0401225 |
| RPL35A | ribosomal protein L35a | -0.0399141 |
| MATR3 | matrin 3 | -0.0386849 |
| DDX3X | DEAD (Asp-Glu-Ala-Asp) box helicase 3, X-linked | -0.0361591 |
| RPL4 | ribosomal protein L4 | -0.0338587 |
| RPL31 | ribosomal protein L31 | -0.0328909 |
| HSPA5 | heat shock 70kDa protein 5 (glucose-regulated protein, 78kDa) | -0.0326674 |
| RPS5 | ribosomal protein S5 | -0.0306121 |
| ALDH7A1 | aldehyde dehydrogenase 7 family, member A1 | -0.0294634 |
| RAB6A | RAB6A, member RAS oncogene family | -0.0289391 |
| HSPD1 | heat shock 60kDa protein 1 (chaperonin) | -0.0288799 |
| RPL32 | ribosomal protein L32 | -0.0284501 |
| RPL12 | ribosomal protein L12 | -0.0265476 |
| PPP3R1 | protein phosphatase 3, regulatory subunit B, alpha | -0.0263261 |
| RPL23 | ribosomal protein L23 | -0.025888 |
| RPS19 | ribosomal protein S19 | -0.0242031 |
| HNRNPU | heterogeneous nuclear ribonucleoprotein U (scaffold attachment factor A) | -0.0237703 |
| RPS25 | ribosomal protein S25 | -0.0236048 |
| YWHAB | tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, beta | -0.0230852 |
| HMGB1 | high mobility group box 1 | -0.0226445 |
| AP3B1 | adaptor-related protein complex 3, beta 1 subunit | -0.0221027 |
| PALS2 | protein associated with LIN7 2, MAGUK p55 family member | -0.0217118 |
| MARCHF6 | membrane associated ring-CH-type finger 6 | -0.0211974 |
| PDS5B | PDS5 cohesin associated factor B | -0.0210856 |
| DNAJA1 | DnaJ (Hsp40) homolog, subfamily A, member 1 | -0.0206698 |
| RPS13 | ribosomal protein S13 | -0.020226 |
| NPM1 | nucleophosmin (nucleolar phosphoprotein B23, numatrin) | -0.0201705 |
| PPP2CA | protein phosphatase 2, catalytic subunit, alpha isozyme | -0.0201361 |
| RPS17 | ribosomal protein S17 | -0.0199039 |
| HMGB2 | high mobility group box 2 | -0.0198657 |
| HNRNPK | heterogeneous nuclear ribonucleoprotein K | -0.0197741 |
| RAP1B | RAP1B, member of RAS oncogene family | -0.0197686 |
| ANAPC5 | anaphase promoting complex subunit 5 | -0.0196594 |
| HSPA9 | heat shock 70kDa protein 9 (mortalin) | -0.0195704 |
| ARPC2 | actin related protein 2/3 complex, subunit 2, 34kDa | -0.0195125 |
| ACSL3 | acyl-CoA synthetase long-chain family member 3 | -0.0192723 |
| MYL12B | myosin, light chain 12B, regulatory | -0.0191111 |
| SF3B2 | splicing factor 3b, subunit 2, 145kDa | -0.0190786 |
| RAB1A | RAB1A, member RAS oncogene family | -0.0189294 |
| RPL38 | ribosomal protein L38 | -0.0188682 |
| RPL9 | ribosomal protein L9 | -0.0186834 |
| RPS21 | ribosomal protein S21 | -0.018507 |
| CALM2 | calmodulin 2 (phosphorylase kinase, delta) | -0.0183048 |
| ZFAND6 | zinc finger, AN1-type domain 6 | -0.0182346 |
| USP3 | ubiquitin specific peptidase 3 | -0.0180814 |
| SINHCAF | SIN3-HDAC complex associated factor | -0.0179081 |
| XPO1 | exportin 1 | -0.0177966 |
| PKM | pyruvate kinase, muscle | -0.0177629 |
| QKI | QKI, KH domain containing, RNA binding | -0.0176341 |
| SCAF11 | SR-related CTD-associated factor 11 | -0.0175087 |
| RNF145 | ring finger protein 145 | -0.0174087 |
| PSMD12 | proteasome (prosome, macropain) 26S subunit, non-ATPase, 12 | -0.0170901 |
| ZC3H15 | zinc finger CCCH-type containing 15 | -0.0170859 |
| TM9SF3 | transmembrane 9 superfamily member 3 | -0.0170365 |
| YBX3 | Y box binding protein 3 | -0.0169979 |
| CBX3 | chromobox homolog 3 | -0.016943 |
| MYL12A | myosin, light chain 12A, regulatory, non-sarcomeric | -0.0169365 |
| RUNX1 | runt-related transcription factor 1 | -0.0169296 |
| IFRD1 | interferon-related developmental regulator 1 | -0.0167141 |
| TLK1 | tousled-like kinase 1 | -0.0166861 |
| WRN | Werner syndrome, RecQ helicase-like | -0.0165169 |
| JMJD1C | jumonji domain containing 1C | -0.0165056 |
| LYPLA1 | lysophospholipase I | -0.0164844 |
| ZNF217 | zinc finger protein 217 | -0.0164683 |
| YES1 | YES proto-oncogene 1, Src family tyrosine kinase | -0.0164609 |
| NDRG1 | N-myc downstream regulated 1 | -0.0163322 |
| RPS4X | ribosomal protein S4, X-linked | -0.0162594 |
| RPS11 | ribosomal protein S11 | -0.0160562 |
| GABARAPL2 | GABA(A) receptor-associated protein-like 2 | -0.0160216 |
| RHEB | Ras homolog enriched in brain | -0.0160211 |
| NOP58 | NOP58 ribonucleoprotein | -0.0159061 |
| FNDC3B | fibronectin type III domain containing 3B | -0.0158355 |
| ARL5B | ADP-ribosylation factor-like 5B | -0.0156895 |
| ACSL4 | acyl-CoA synthetase long-chain family member 4 | -0.0156704 |
| MORF4L1 | mortality factor 4 like 1 | -0.0156637 |
| S100A9 | S100 calcium binding protein A9 | -0.0156584 |
| VAPA | VAMP (vesicle-associated membrane protein)-associated protein A, 33kDa | -0.015479 |
| CCT4 | chaperonin containing TCP1, subunit 4 (delta) | -0.0154754 |
| SNX3 | sorting nexin 3 | -0.0153349 |
| CBL | Cbl proto-oncogene, E3 ubiquitin protein ligase | -0.015333 |
| FTL | ferritin, light polypeptide | -0.0152815 |
| RPS28 | ribosomal protein S28 | -0.0152524 |
| RPS3 | ribosomal protein S3 | -0.0152068 |
| EML4 | echinoderm microtubule associated protein like 4 | -0.0151597 |
| DHX9 | DEAH (Asp-Glu-Ala-His) box helicase 9 | -0.0151343 |
| PNRC1 | proline-rich nuclear receptor coactivator 1 | -0.0150257 |
| NAMPT | nicotinamide phosphoribosyltransferase | -0.0150026 |
| TAX1BP1 | Tax1 (human T-cell leukemia virus type I) binding protein 1 | -0.0150002 |
| SPRED2 | sprouty-related, EVH1 domain containing 2 | -0.0149754 |
| SREK1 | splicing regulatory glutamine/lysine-rich protein 1 | -0.0149619 |
| RPL5 | ribosomal protein L5 | -0.0149232 |
| DEK | DEK proto-oncogene | -0.0149147 |
| FAM222B | family with sequence similarity 222, member B | -0.0148714 |
| NPEPPS | aminopeptidase puromycin sensitive | -0.0148007 |
| MDM2 | MDM2 proto-oncogene, E3 ubiquitin protein ligase | -0.0147501 |
