| Dataset | Tahoe Therapeutics Tahoe 100M Perturbation Atlas |
| Category | transcriptomics |
| Type | cell type |
| Description | Esmolol (hydrochloride) perturbation in CHP-212 cell line (Tahoe Therapeutics) |
| Similar Terms | |
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200 genes differentially expressed following the Esmolol (hydrochloride)_CHP-212 drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| IGF2 | insulin-like growth factor 2 | 0.209206 |
| FMN1 | formin 1 | 0.150674 |
| GAPDH | glyceraldehyde-3-phosphate dehydrogenase | 0.130876 |
| PTPRD | protein tyrosine phosphatase, receptor type, D | 0.118907 |
| LSAMP | limbic system-associated membrane protein | 0.112811 |
| MEIS2 | Meis homeobox 2 | 0.110441 |
| SYT1 | synaptotagmin I | 0.093578 |
| PRKCA | protein kinase C, alpha | 0.0866741 |
| LGR5 | leucine-rich repeat containing G protein-coupled receptor 5 | 0.0815893 |
| NALF1 | NALCN channel auxiliary factor 1 | 0.0729253 |
| NRG1 | neuregulin 1 | 0.0672071 |
| MAP1B | microtubule-associated protein 1B | 0.0656347 |
| RBMS3 | RNA binding motif, single stranded interacting protein 3 | 0.0655676 |
| LINGO2 | leucine rich repeat and Ig domain containing 2 | 0.0615343 |
| RNF213 | ring finger protein 213 | 0.0605038 |
| TPST1 | tyrosylprotein sulfotransferase 1 | 0.0594715 |
| LIMCH1 | LIM and calponin homology domains 1 | 0.0575442 |
| FAM13A | family with sequence similarity 13, member A | 0.0573228 |
| ANTXR1 | anthrax toxin receptor 1 | 0.0572544 |
| GULP1 | GULP, engulfment adaptor PTB domain containing 1 | 0.0555492 |
| LRFN5 | leucine rich repeat and fibronectin type III domain containing 5 | 0.0535933 |
| PSD3 | pleckstrin and Sec7 domain containing 3 | 0.0528259 |
| REV3L | REV3-like, polymerase (DNA directed), zeta, catalytic subunit | 0.052462 |
| NCAM2 | neural cell adhesion molecule 2 | 0.0507846 |
| SOS1 | son of sevenless homolog 1 (Drosophila) | 0.0484331 |
| MBD5 | methyl-CpG binding domain protein 5 | 0.048081 |
| BPTF | bromodomain PHD finger transcription factor | 0.0476394 |
| HELZ | helicase with zinc finger | 0.0475804 |
| MEF2A | myocyte enhancer factor 2A | 0.0458695 |
| PDE3A | phosphodiesterase 3A, cGMP-inhibited | 0.0444683 |
| SLC6A6 | solute carrier family 6 (neurotransmitter transporter), member 6 | 0.0440151 |
| HILPDA | hypoxia inducible lipid droplet-associated | 0.0429039 |
| CRH | corticotropin releasing hormone | 0.0423478 |
| UBR5 | ubiquitin protein ligase E3 component n-recognin 5 | 0.0416265 |
| ITPRID2 | ITPR interacting domain containing 2 | 0.0393809 |
| SMYD3 | SET and MYND domain containing 3 | 0.0391142 |
| MSI2 | musashi RNA-binding protein 2 | 0.0388513 |
| PTPRK | protein tyrosine phosphatase, receptor type, K | 0.0384181 |
| PLCB1 | phospholipase C, beta 1 (phosphoinositide-specific) | 0.0382144 |
| FRMD4A | FERM domain containing 4A | 0.0378414 |
| VCL | vinculin | 0.0374878 |
| ZBTB20 | zinc finger and BTB domain containing 20 | 0.0374324 |
| SCN9A | sodium channel, voltage gated, type IX alpha subunit | 0.0369806 |
| ST6GALNAC3 | ST6 (alpha-N-acetyl-neuraminyl-2,3-beta-galactosyl-1,3)-N-acetylgalactosaminide alpha-2,6-sialyltransferase 3 | 0.0368122 |
| GLCCI1 | glucocorticoid induced 1 | 0.0367079 |
| CDH10 | cadherin 10, type 2 (T2-cadherin) | 0.0353489 |
| PLPP1 | phospholipid phosphatase 1 | 0.0350915 |
| FNBP1 | formin binding protein 1 | 0.0343828 |
| HMBOX1 | homeobox containing 1 | 0.0341777 |
| STAT1 | signal transducer and activator of transcription 1, 91kDa | 0.0341649 |
| NFAT5 | nuclear factor of activated T-cells 5, tonicity-responsive | 0.0339936 |
| SIK2 | salt-inducible kinase 2 | 0.0336595 |
| RAD51B | RAD51 paralog B | 0.0334451 |
| DST | dystonin | 0.0331648 |
| FNDC3A | fibronectin type III domain containing 3A | 0.0322379 |
| RBPJ | recombination signal binding protein for immunoglobulin kappa J region | 0.0319955 |
| P4HB | prolyl 4-hydroxylase, beta polypeptide | 0.0315079 |
| STAT3 | signal transducer and activator of transcription 3 (acute-phase response factor) | 0.0314472 |
| PTPRM | protein tyrosine phosphatase, receptor type, M | 0.0312968 |
| SEPTIN9 | septin 9 | 0.0311978 |
| TMTC2 | transmembrane and tetratricopeptide repeat containing 2 | 0.0311042 |
| AKAP12 | A kinase (PRKA) anchor protein 12 | 0.0309747 |
| GAB2 | GRB2-associated binding protein 2 | 0.030733 |
| SLITRK6 | SLIT and NTRK-like family, member 6 | 0.0306899 |
| TCF7L2 | transcription factor 7-like 2 (T-cell specific, HMG-box) | 0.0300933 |
| MAN1A1 | mannosidase, alpha, class 1A, member 1 | 0.0299801 |
| NREP | neuronal regeneration related protein | 0.0299294 |
| KLHL13 | kelch-like family member 13 | 0.0293743 |
| FNDC3B | fibronectin type III domain containing 3B | 0.0293622 |
| ANGPT1 | angiopoietin 1 | 0.0292175 |
| COL1A1 | collagen, type I, alpha 1 | 0.0288361 |
| TRIO | trio Rho guanine nucleotide exchange factor | 0.0286815 |
| P4HA1 | prolyl 4-hydroxylase, alpha polypeptide I | 0.0283884 |
| AUTS2 | autism susceptibility candidate 2 | 0.0283608 |
| VMP1 | vacuole membrane protein 1 | 0.0280404 |
| BCAS3 | breast carcinoma amplified sequence 3 | 0.0275259 |
| GREM2 | gremlin 2, DAN family BMP antagonist | 0.0274471 |
| SRRM2 | serine/arginine repetitive matrix 2 | 0.0273715 |
| ADAMTS9 | ADAM metallopeptidase with thrombospondin type 1 motif, 9 | 0.0272759 |
| ADARB1 | adenosine deaminase, RNA-specific, B1 | 0.0271213 |
| EXT1 | exostosin glycosyltransferase 1 | 0.0269325 |
| COL4A5 | collagen, type IV, alpha 5 | 0.026508 |
| NPEPPS | aminopeptidase puromycin sensitive | 0.0263074 |
| MBNL2 | muscleblind-like splicing regulator 2 | 0.0262765 |
| TET2 | tet methylcytosine dioxygenase 2 | 0.026145 |
| ADGRB3 | adhesion G protein-coupled receptor B3 | 0.0258932 |
| RGS4 | regulator of G-protein signaling 4 | 0.0256554 |
| FERMT2 | fermitin family member 2 | 0.0255994 |
| TANC2 | tetratricopeptide repeat, ankyrin repeat and coiled-coil containing 2 | 0.0255541 |
| CD46 | CD46 molecule, complement regulatory protein | 0.0254181 |
| BAZ2B | bromodomain adjacent to zinc finger domain, 2B | 0.0254046 |
| GBE1 | glucan (1,4-alpha-), branching enzyme 1 | 0.0253978 |
| PABPC1 | poly(A) binding protein, cytoplasmic 1 | 0.0253079 |
| IFI16 | interferon, gamma-inducible protein 16 | 0.0251967 |
| CHD9 | chromodomain helicase DNA binding protein 9 | 0.0251411 |
| PBX1 | pre-B-cell leukemia homeobox 1 | 0.0251088 |
| PLAT | plasminogen activator, tissue | 0.0249632 |
| THSD4 | thrombospondin, type I, domain containing 4 | 0.0248492 |
| RALYL | RALY RNA binding protein-like | 0.0246269 |
| MMP16 | matrix metallopeptidase 16 (membrane-inserted) | 0.0244728 |
| Symbol | Name | Standardized Value |
|---|---|---|
| DDX1 | DEAD (Asp-Glu-Ala-Asp) box helicase 1 | -0.12951 |
| VIM | vimentin | -0.0890131 |
| PTMA | prothymosin, alpha | -0.0860213 |
| HSPA5 | heat shock 70kDa protein 5 (glucose-regulated protein, 78kDa) | -0.0613238 |
| AHNAK | AHNAK nucleoprotein | -0.0588716 |
| NPM1 | nucleophosmin (nucleolar phosphoprotein B23, numatrin) | -0.0546417 |
| RPS24 | ribosomal protein S24 | -0.0515325 |
| HSP90AA1 | heat shock protein 90kDa alpha (cytosolic), class A member 1 | -0.0486733 |
| RPL35A | ribosomal protein L35a | -0.0466029 |
| TMSB10 | thymosin beta 10 | -0.0418114 |
| RPS27A | ribosomal protein S27a | -0.0417055 |
| RPL38 | ribosomal protein L38 | -0.0395833 |
| ACTG1 | actin gamma 1 | -0.0393807 |
| RPL34 | ribosomal protein L34 | -0.0391787 |
| RPLP1 | ribosomal protein, large, P1 | -0.0372795 |
| RPL11 | ribosomal protein L11 | -0.0369456 |
| HNRNPU | heterogeneous nuclear ribonucleoprotein U (scaffold attachment factor A) | -0.0368934 |
| UBC | ubiquitin C | -0.0365035 |
| IER3 | immediate early response 3 | -0.0363773 |
| RPS25 | ribosomal protein S25 | -0.0339523 |
| RPL23 | ribosomal protein L23 | -0.0338772 |
| RPS8 | ribosomal protein S8 | -0.0335198 |
| S100A6 | S100 calcium binding protein A6 | -0.0335042 |
| LPIN1 | lipin 1 | -0.0332415 |
| NAP1L1 | nucleosome assembly protein 1-like 1 | -0.032657 |
| CANX | calnexin | -0.0319606 |
| HMGB2 | high mobility group box 2 | -0.0311366 |
| RPLP0 | ribosomal protein, large, P0 | -0.0290721 |
| TPT1 | tumor protein, translationally-controlled 1 | -0.028849 |
| EFNA5 | ephrin-A5 | -0.0277027 |
| TM4SF1 | transmembrane 4 L six family member 1 | -0.0270469 |
| KDM3A | lysine (K)-specific demethylase 3A | -0.0267788 |
| OGA | O-GlcNAcase | -0.0258651 |
| LOC102724023 | ES1 protein homolog, mitochondrial | -0.0257294 |
| DNAJA1 | DnaJ (Hsp40) homolog, subfamily A, member 1 | -0.0250039 |
| CTNND1 | catenin (cadherin-associated protein), delta 1 | -0.0248495 |
| SRPK2 | SRSF protein kinase 2 | -0.0248135 |
| RPS16 | ribosomal protein S16 | -0.0246048 |
| RPS27 | ribosomal protein S27 | -0.0239933 |
| RPS23 | ribosomal protein S23 | -0.0238314 |
| TUBA1B | tubulin, alpha 1b | -0.0234178 |
| CAPN2 | calpain 2, (m/II) large subunit | -0.0231891 |
| S100A10 | S100 calcium binding protein A10 | -0.023075 |
| ANXA2 | annexin A2 | -0.0225922 |
| TOMM20 | translocase of outer mitochondrial membrane 20 homolog (yeast) | -0.0222678 |
| HMGA2 | high mobility group AT-hook 2 | -0.0220339 |
| RPL12 | ribosomal protein L12 | -0.0218187 |
| RPL9 | ribosomal protein L9 | -0.0217818 |
| RPS17 | ribosomal protein S17 | -0.0217333 |
| RPL31 | ribosomal protein L31 | -0.0216905 |
| PRPF40A | PRP40 pre-mRNA processing factor 40 homolog A (S. cerevisiae) | -0.0213958 |
| HNRNPH1 | heterogeneous nuclear ribonucleoprotein H1 (H) | -0.0211026 |
| HNRNPA2B1 | heterogeneous nuclear ribonucleoprotein A2/B1 | -0.0209608 |
| PDLIM5 | PDZ and LIM domain 5 | -0.0207807 |
| SMG1 | SMG1 phosphatidylinositol 3-kinase-related kinase | -0.0206484 |
| ENO1 | enolase 1, (alpha) | -0.0205473 |
| UBE2K | ubiquitin-conjugating enzyme E2K | -0.0201003 |
| NPR2 | natriuretic peptide receptor 2 | -0.0200834 |
| PPP6R3 | protein phosphatase 6, regulatory subunit 3 | -0.019904 |
| LMNA | lamin A/C | -0.0198836 |
| RPL36A | ribosomal protein L36a | -0.0198384 |
| SERPINE1 | serpin peptidase inhibitor, clade E (nexin, plasminogen activator inhibitor type 1), member 1 | -0.0198368 |
| TFDP2 | transcription factor Dp-2 (E2F dimerization partner 2) | -0.0198196 |
| PDE4D | phosphodiesterase 4D, cAMP-specific | -0.0197577 |
| ARID4B | AT rich interactive domain 4B (RBP1-like) | -0.0197266 |
| USP34 | ubiquitin specific peptidase 34 | -0.0196089 |
| KCNMA1 | potassium channel, calcium activated large conductance subfamily M alpha, member 1 | -0.0193816 |
| RPL32 | ribosomal protein L32 | -0.0191087 |
| MATR3 | matrin 3 | -0.0188948 |
| RBMX | RNA binding motif protein, X-linked | -0.0187969 |
| NCOA2 | nuclear receptor coactivator 2 | -0.0186823 |
| PARD3 | par-3 family cell polarity regulator | -0.018617 |
| TXNRD1 | thioredoxin reductase 1 | -0.0183865 |
| EEF2 | eukaryotic translation elongation factor 2 | -0.0183805 |
| HSP90B1 | heat shock protein 90kDa beta (Grp94), member 1 | -0.0182192 |
| ELF2 | E74-like factor 2 (ets domain transcription factor) | -0.0181768 |
| MT2A | metallothionein 2A | -0.0181304 |
| RPS29 | ribosomal protein S29 | -0.0181115 |
| CDH13 | cadherin 13 | -0.0178776 |
| ITGB1 | integrin, beta 1 (fibronectin receptor, beta polypeptide, antigen CD29 includes MDF2, MSK12) | -0.0177917 |
| MAP2K4 | mitogen-activated protein kinase kinase 4 | -0.0177144 |
| EIF3A | eukaryotic translation initiation factor 3, subunit A | -0.0176766 |
| HDAC2 | histone deacetylase 2 | -0.0176239 |
| RPS11 | ribosomal protein S11 | -0.017599 |
| MTDH | metadherin | -0.0175613 |
| MAP4K3 | mitogen-activated protein kinase kinase kinase kinase 3 | -0.0173772 |
| GCC2 | GRIP and coiled-coil domain containing 2 | -0.0173102 |
| SLC7A11 | solute carrier family 7 (anionic amino acid transporter light chain, xc- system), member 11 | -0.0171436 |
| MACF1 | microtubule-actin crosslinking factor 1 | -0.0170925 |
| ACSL3 | acyl-CoA synthetase long-chain family member 3 | -0.0169322 |
| SLC25A36 | solute carrier family 25 (pyrimidine nucleotide carrier), member 36 | -0.0169076 |
| FUS | FUS RNA binding protein | -0.0168857 |
| UBE2O | ubiquitin-conjugating enzyme E2O | -0.0168745 |
| SENP5 | SUMO1/sentrin specific peptidase 5 | -0.0167399 |
| RPS13 | ribosomal protein S13 | -0.016721 |
| ACTR2 | ARP2 actin-related protein 2 homolog (yeast) | -0.0167054 |
| SH3KBP1 | SH3-domain kinase binding protein 1 | -0.0166176 |
| CALM2 | calmodulin 2 (phosphorylase kinase, delta) | -0.0165485 |
| VCP | valosin containing protein | -0.0164825 |
| MAP4K4 | mitogen-activated protein kinase kinase kinase kinase 4 | -0.0164293 |
