| Dataset | Tahoe Therapeutics Tahoe 100M Perturbation Atlas |
| Category | transcriptomics |
| Type | cell type |
| Description | Esmolol (hydrochloride) perturbation in COLO 205 cell line (Tahoe Therapeutics) |
| Similar Terms | |
| Downloads & Tools |
200 genes differentially expressed following the Esmolol (hydrochloride)_COLO 205 drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| SPTBN1 | spectrin, beta, non-erythrocytic 1 | 0.196031 |
| LMO7 | LIM domain 7 | 0.169788 |
| MYO1E | myosin IE | 0.131309 |
| MACC1 | metastasis associated in colon cancer 1 | 0.128837 |
| DSCAM | Down syndrome cell adhesion molecule | 0.118231 |
| DNAJC15 | DnaJ (Hsp40) homolog, subfamily C, member 15 | 0.113435 |
| H1-0 | H1.0 linker histone | 0.0932592 |
| SCD | stearoyl-CoA desaturase (delta-9-desaturase) | 0.0872259 |
| TMC5 | transmembrane channel-like 5 | 0.0828434 |
| SPATA13 | spermatogenesis associated 13 | 0.0734847 |
| VMP1 | vacuole membrane protein 1 | 0.0722745 |
| FOS | FBJ murine osteosarcoma viral oncogene homolog | 0.0703238 |
| SLC12A2 | solute carrier family 12 (sodium/potassium/chloride transporter), member 2 | 0.0691264 |
| JUN | jun proto-oncogene | 0.0682073 |
| EGR1 | early growth response 1 | 0.0679315 |
| SQSTM1 | sequestosome 1 | 0.0646052 |
| SYNE2 | spectrin repeat containing, nuclear envelope 2 | 0.0625867 |
| TRIM2 | tripartite motif containing 2 | 0.0619817 |
| HLA-B | major histocompatibility complex, class I, B | 0.0616487 |
| SNTB1 | syntrophin, beta 1 (dystrophin-associated protein A1, 59kDa, basic component 1) | 0.0575683 |
| SRRM2 | serine/arginine repetitive matrix 2 | 0.0565069 |
| STAT3 | signal transducer and activator of transcription 3 (acute-phase response factor) | 0.0524446 |
| MBNL2 | muscleblind-like splicing regulator 2 | 0.0518358 |
| MYH9 | myosin, heavy chain 9, non-muscle | 0.0517598 |
| PLSCR1 | phospholipid scramblase 1 | 0.0514107 |
| RAB7A | RAB7A, member RAS oncogene family | 0.0511727 |
| ACTN4 | actinin, alpha 4 | 0.0499107 |
| EPS8 | epidermal growth factor receptor pathway substrate 8 | 0.0491517 |
| STK24 | serine/threonine kinase 24 | 0.0490197 |
| PHF3 | PHD finger protein 3 | 0.0469346 |
| EZR | ezrin | 0.0446629 |
| GOLGB1 | golgin B1 | 0.0446009 |
| DUSP10 | dual specificity phosphatase 10 | 0.0432777 |
| ELOF1 | elongation factor 1 homolog (S. cerevisiae) | 0.0430392 |
| ERN1 | endoplasmic reticulum to nucleus signaling 1 | 0.042931 |
| ADIPOR2 | adiponectin receptor 2 | 0.0421958 |
| FHL2 | four and a half LIM domains 2 | 0.0412707 |
| NAMPT | nicotinamide phosphoribosyltransferase | 0.0412318 |
| MGAT5 | mannosyl (alpha-1,6-)-glycoprotein beta-1,6-N-acetyl-glucosaminyltransferase | 0.0410749 |
| ATP11A | ATPase, class VI, type 11A | 0.0407671 |
| CPEB4 | cytoplasmic polyadenylation element binding protein 4 | 0.0404793 |
| PPARGC1A | peroxisome proliferator-activated receptor gamma, coactivator 1 alpha | 0.0393542 |
| EPHB2 | EPH receptor B2 | 0.0393409 |
| TC2N | tandem C2 domains, nuclear | 0.0392332 |
| SHB | Src homology 2 domain containing adaptor protein B | 0.0385779 |
| RUNX1 | runt-related transcription factor 1 | 0.0379065 |
| OAS1 | 2'-5'-oligoadenylate synthetase 1, 40/46kDa | 0.0375553 |
| ZC3H13 | zinc finger CCCH-type containing 13 | 0.0364376 |
| ST14 | suppression of tumorigenicity 14 (colon carcinoma) | 0.0364258 |
| ARGLU1 | arginine and glutamate rich 1 | 0.0363195 |
| ARIH1 | ariadne RBR E3 ubiquitin protein ligase 1 | 0.0362268 |
| IGF2R | insulin-like growth factor 2 receptor | 0.0350296 |
| RALGAPA2 | Ral GTPase activating protein, alpha subunit 2 (catalytic) | 0.0348998 |
| FNIP2 | folliculin interacting protein 2 | 0.0337624 |
| MAN1A1 | mannosidase, alpha, class 1A, member 1 | 0.0337402 |
| BTBD9 | BTB (POZ) domain containing 9 | 0.0330773 |
| SMAD3 | SMAD family member 3 | 0.0330692 |
| APLP2 | amyloid beta (A4) precursor-like protein 2 | 0.0330692 |
| PHACTR4 | phosphatase and actin regulator 4 | 0.0330307 |
| ITPKC | inositol-trisphosphate 3-kinase C | 0.0326055 |
| EXT1 | exostosin glycosyltransferase 1 | 0.032446 |
| TMEM62 | transmembrane protein 62 | 0.0321677 |
| AKAP9 | A kinase (PRKA) anchor protein 9 | 0.0316134 |
| SLK | STE20-like kinase | 0.0311281 |
| CHST11 | carbohydrate (chondroitin 4) sulfotransferase 11 | 0.0310812 |
| NRIP1 | nuclear receptor interacting protein 1 | 0.0305698 |
| IL20RA | interleukin 20 receptor, alpha | 0.030352 |
| OAS3 | 2'-5'-oligoadenylate synthetase 3, 100kDa | 0.0302215 |
| NKD1 | naked cuticle homolog 1 (Drosophila) | 0.0298539 |
| UBR1 | ubiquitin protein ligase E3 component n-recognin 1 | 0.0298146 |
| IGF1R | insulin-like growth factor 1 receptor | 0.0297244 |
| TOP1 | topoisomerase (DNA) I | 0.0293549 |
| AOPEP | aminopeptidase O (putative) | 0.0293288 |
| ATF6 | activating transcription factor 6 | 0.0289964 |
| UBR5 | ubiquitin protein ligase E3 component n-recognin 5 | 0.0288104 |
| SPAG9 | sperm associated antigen 9 | 0.0287117 |
| FDPS | farnesyl diphosphate synthase | 0.0285895 |
| CXCL8 | chemokine (C-X-C motif) ligand 8 | 0.0285813 |
| ASH1L | ash1 (absent, small, or homeotic)-like (Drosophila) | 0.0285071 |
| SMURF1 | SMAD specific E3 ubiquitin protein ligase 1 | 0.0283844 |
| LRCH1 | leucine-rich repeats and calponin homology (CH) domain containing 1 | 0.0281998 |
| GOLGA2 | golgin A2 | 0.0280209 |
| TUFT1 | tuftelin 1 | 0.0279858 |
| ETNK1 | ethanolamine kinase 1 | 0.0279561 |
| DUSP16 | dual specificity phosphatase 16 | 0.0278425 |
| SERINC5 | serine incorporator 5 | 0.0277119 |
| LRRFIP1 | leucine rich repeat (in FLII) interacting protein 1 | 0.0276675 |
| ZC3HAV1 | zinc finger CCCH-type, antiviral 1 | 0.0276439 |
| LURAP1L | leucine rich adaptor protein 1-like | 0.0275485 |
| CANX | calnexin | 0.0274404 |
| LOC102724023 | ES1 protein homolog, mitochondrial | 0.0274396 |
| LOC112694756 | uncharaterized LOC112694756 | 0.0272004 |
| USP54 | ubiquitin specific peptidase 54 | 0.0270999 |
| APP | amyloid beta (A4) precursor protein | 0.0269795 |
| MLPH | melanophilin | 0.0268835 |
| UBL3 | ubiquitin-like 3 | 0.0267486 |
| NECTIN2 | nectin cell adhesion molecule 2 | 0.0266853 |
| NCKAP5 | NCK-associated protein 5 | 0.0265553 |
| AHI1 | Abelson helper integration site 1 | 0.0264024 |
| HDAC4 | histone deacetylase 4 | 0.0263729 |
| Symbol | Name | Standardized Value |
|---|---|---|
| FNDC3B | fibronectin type III domain containing 3B | -0.0994557 |
| LYZ | lysozyme | -0.0855063 |
| PTMA | prothymosin, alpha | -0.0768207 |
| PERP | PERP, TP53 apoptosis effector | -0.0716744 |
| HSPA5 | heat shock 70kDa protein 5 (glucose-regulated protein, 78kDa) | -0.0696236 |
| ERO1A | endoplasmic reticulum oxidoreductase 1 alpha | -0.0659038 |
| ASPH | aspartate beta-hydroxylase | -0.0607962 |
| DDX60 | DEAD (Asp-Glu-Ala-Asp) box polypeptide 60 | -0.0588183 |
| PKM | pyruvate kinase, muscle | -0.0586425 |
| PGK1 | phosphoglycerate kinase 1 | -0.0568612 |
| PLSCR2 | phospholipid scramblase 2 | -0.0563517 |
| MT2A | metallothionein 2A | -0.0561207 |
| TMSB10 | thymosin beta 10 | -0.0515543 |
| HCN1 | hyperpolarization activated cyclic nucleotide gated potassium channel 1 | -0.0488838 |
| NPSR1 | neuropeptide S receptor 1 | -0.0465937 |
| GBE1 | glucan (1,4-alpha-), branching enzyme 1 | -0.045918 |
| P4HA1 | prolyl 4-hydroxylase, alpha polypeptide I | -0.0433069 |
| RNF149 | ring finger protein 149 | -0.0431531 |
| ERRFI1 | ERBB receptor feedback inhibitor 1 | -0.0417902 |
| NT5C3A | 5'-nucleotidase, cytosolic IIIA | -0.0413757 |
| MEF2A | myocyte enhancer factor 2A | -0.0405223 |
| FTL | ferritin, light polypeptide | -0.0393459 |
| PLOD2 | procollagen-lysine, 2-oxoglutarate 5-dioxygenase 2 | -0.0392226 |
| IGFBP3 | insulin-like growth factor binding protein 3 | -0.0384484 |
| STS | steroid sulfatase (microsomal), isozyme S | -0.0383997 |
| SP100 | SP100 nuclear antigen | -0.0380103 |
| IFI6 | interferon, alpha-inducible protein 6 | -0.0376532 |
| GAPDH | glyceraldehyde-3-phosphate dehydrogenase | -0.0371091 |
| EFNB2 | ephrin-B2 | -0.0355141 |
| DNAJC3 | DnaJ (Hsp40) homolog, subfamily C, member 3 | -0.0350527 |
| TM4SF19 | transmembrane 4 L six family member 19 | -0.0342497 |
| INTS6 | integrator complex subunit 6 | -0.0340885 |
| HSP90AA1 | heat shock protein 90kDa alpha (cytosolic), class A member 1 | -0.034034 |
| RPL35A | ribosomal protein L35a | -0.0340119 |
| IFIT2 | interferon-induced protein with tetratricopeptide repeats 2 | -0.0339756 |
| S100A10 | S100 calcium binding protein A10 | -0.0325881 |
| LDHA | lactate dehydrogenase A | -0.0323103 |
| PABPC1 | poly(A) binding protein, cytoplasmic 1 | -0.0318056 |
| GNAS | GNAS complex locus | -0.0314838 |
| GMDS | GDP-mannose 4,6-dehydratase | -0.0314588 |
| TPT1 | tumor protein, translationally-controlled 1 | -0.0311219 |
| ABLIM1 | actin binding LIM protein 1 | -0.0308828 |
| TM9SF2 | transmembrane 9 superfamily member 2 | -0.0306806 |
| TSHZ2 | teashirt zinc finger homeobox 2 | -0.0306615 |
| DLG1 | discs, large homolog 1 (Drosophila) | -0.0300787 |
| ARHGAP26 | Rho GTPase activating protein 26 | -0.0299886 |
| PLA2G2A | phospholipase A2, group IIA (platelets, synovial fluid) | -0.0293421 |
| LAMA4 | laminin, alpha 4 | -0.0293248 |
| RPL7A | ribosomal protein L7a | -0.0293099 |
| RPS25 | ribosomal protein S25 | -0.0291172 |
| CTSD | cathepsin D | -0.0284461 |
| KRT19 | keratin 19, type I | -0.0282486 |
| IFIT3 | interferon-induced protein with tetratricopeptide repeats 3 | -0.0281479 |
| HNRNPA2B1 | heterogeneous nuclear ribonucleoprotein A2/B1 | -0.0276201 |
| AP3B1 | adaptor-related protein complex 3, beta 1 subunit | -0.0273255 |
| FNIP1 | folliculin interacting protein 1 | -0.0272754 |
| KLF5 | Kruppel-like factor 5 (intestinal) | -0.0266891 |
| MAP7 | microtubule-associated protein 7 | -0.026495 |
| TPI1 | triosephosphate isomerase 1 | -0.0263802 |
| PHLDA1 | pleckstrin homology-like domain, family A, member 1 | -0.0263042 |
| POTEF | POTE ankyrin domain family, member F | -0.0259244 |
| USP34 | ubiquitin specific peptidase 34 | -0.0257199 |
| RPLP1 | ribosomal protein, large, P1 | -0.0252848 |
| CTNNA1 | catenin (cadherin-associated protein), alpha 1, 102kDa | -0.025159 |
| ARPC2 | actin related protein 2/3 complex, subunit 2, 34kDa | -0.0249875 |
| ZMYM2 | zinc finger, MYM-type 2 | -0.0247883 |
| TNFSF10 | tumor necrosis factor (ligand) superfamily, member 10 | -0.0246692 |
| MAML2 | mastermind-like 2 (Drosophila) | -0.0246609 |
| RPS6 | ribosomal protein S6 | -0.0246173 |
| RPL12 | ribosomal protein L12 | -0.0242553 |
| RPS24 | ribosomal protein S24 | -0.0240337 |
| TFF3 | trefoil factor 3 (intestinal) | -0.0233479 |
| GPRC5A | G protein-coupled receptor, class C, group 5, member A | -0.0232289 |
| RPS3 | ribosomal protein S3 | -0.0232152 |
| PTK2 | protein tyrosine kinase 2 | -0.023212 |
| GOLGA4 | golgin A4 | -0.0230606 |
| EPSTI1 | epithelial stromal interaction 1 (breast) | -0.0227532 |
| DSCAML1 | Down syndrome cell adhesion molecule like 1 | -0.0224603 |
| XAF1 | XIAP associated factor 1 | -0.0222978 |
| STAU1 | staufen double-stranded RNA binding protein 1 | -0.0221995 |
| TXNRD1 | thioredoxin reductase 1 | -0.0219707 |
| TRAM1 | translocation associated membrane protein 1 | -0.0219259 |
| TFG | TRK-fused gene | -0.021898 |
| PDIA3 | protein disulfide isomerase family A, member 3 | -0.0215568 |
| ITGA2 | integrin, alpha 2 (CD49B, alpha 2 subunit of VLA-2 receptor) | -0.0215049 |
| IFITM3 | interferon induced transmembrane protein 3 | -0.0213413 |
| ACTR2 | ARP2 actin-related protein 2 homolog (yeast) | -0.0213099 |
| MT1X | metallothionein 1X | -0.0212329 |
| RPS19 | ribosomal protein S19 | -0.021195 |
| PDK3 | pyruvate dehydrogenase kinase, isozyme 3 | -0.0211415 |
| KDM2A | lysine (K)-specific demethylase 2A | -0.0209605 |
| RPL23 | ribosomal protein L23 | -0.0208161 |
| ATP1B1 | ATPase, Na+/K+ transporting, beta 1 polypeptide | -0.0206767 |
| RPS23 | ribosomal protein S23 | -0.0206535 |
| TRPM7 | transient receptor potential cation channel, subfamily M, member 7 | -0.0206217 |
| ADAM10 | ADAM metallopeptidase domain 10 | -0.0205337 |
| ABCA1 | ATP-binding cassette, sub-family A (ABC1), member 1 | -0.020497 |
| FAT1 | FAT atypical cadherin 1 | -0.020464 |
| HSPA9 | heat shock 70kDa protein 9 (mortalin) | -0.0203307 |
| C6ORF132 | chromosome 6 open reading frame 132 | -0.0203207 |
