| Dataset | Tahoe Therapeutics Tahoe 100M Perturbation Atlas |
| Category | transcriptomics |
| Type | cell type |
| Description | Esmolol (hydrochloride) perturbation in H4 cell line (Tahoe Therapeutics) |
| Similar Terms | |
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200 genes differentially expressed following the Esmolol (hydrochloride)_H4 drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| COL6A3 | collagen, type VI, alpha 3 | 0.374192 |
| GAPDH | glyceraldehyde-3-phosphate dehydrogenase | 0.191378 |
| FNDC3B | fibronectin type III domain containing 3B | 0.129119 |
| SLC7A11 | solute carrier family 7 (anionic amino acid transporter light chain, xc- system), member 11 | 0.111839 |
| TGFBI | transforming growth factor, beta-induced, 68kDa | 0.107116 |
| IGFBP3 | insulin-like growth factor binding protein 3 | 0.104832 |
| MAP1B | microtubule-associated protein 1B | 0.0960465 |
| CXCL8 | chemokine (C-X-C motif) ligand 8 | 0.0908475 |
| FTH1 | ferritin, heavy polypeptide 1 | 0.0878006 |
| EXT1 | exostosin glycosyltransferase 1 | 0.0852875 |
| KYNU | kynureninase | 0.08425 |
| SBF2 | SET binding factor 2 | 0.0830213 |
| VMP1 | vacuole membrane protein 1 | 0.0788679 |
| OSMR | oncostatin M receptor | 0.0764531 |
| DGKD | diacylglycerol kinase, delta 130kDa | 0.0740781 |
| ZCCHC7 | zinc finger, CCHC domain containing 7 | 0.0689315 |
| SEMA3A | sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3A | 0.0688029 |
| EGFR | epidermal growth factor receptor | 0.0666492 |
| MBD5 | methyl-CpG binding domain protein 5 | 0.0662257 |
| CANX | calnexin | 0.0638994 |
| ANKRD17 | ankyrin repeat domain 17 | 0.0620674 |
| ACTN4 | actinin, alpha 4 | 0.0610445 |
| P4HB | prolyl 4-hydroxylase, beta polypeptide | 0.0604837 |
| LPP | LIM domain containing preferred translocation partner in lipoma | 0.060249 |
| GNPDA1 | glucosamine-6-phosphate deaminase 1 | 0.059892 |
| LOC112694756 | uncharaterized LOC112694756 | 0.0590383 |
| AHNAK | AHNAK nucleoprotein | 0.0584715 |
| TNNC1 | troponin C type 1 (slow) | 0.0574121 |
| SLC6A6 | solute carrier family 6 (neurotransmitter transporter), member 6 | 0.0560454 |
| EGR1 | early growth response 1 | 0.0555922 |
| ACTN1 | actinin, alpha 1 | 0.0552698 |
| ANXA2 | annexin A2 | 0.0552103 |
| TNRC18 | trinucleotide repeat containing 18 | 0.0539693 |
| RABGEF1 | RAB guanine nucleotide exchange factor (GEF) 1 | 0.0537566 |
| CADM1 | cell adhesion molecule 1 | 0.0537077 |
| MICAL2 | microtubule associated monooxygenase, calponin and LIM domain containing 2 | 0.0536256 |
| DST | dystonin | 0.0524392 |
| VCL | vinculin | 0.052368 |
| TTC3 | tetratricopeptide repeat domain 3 | 0.0519115 |
| SMAD3 | SMAD family member 3 | 0.05104 |
| IGF2BP3 | insulin-like growth factor 2 mRNA binding protein 3 | 0.0503507 |
| LDHA | lactate dehydrogenase A | 0.0502861 |
| MAP4K4 | mitogen-activated protein kinase kinase kinase kinase 4 | 0.049633 |
| CALD1 | caldesmon 1 | 0.049347 |
| SCFD2 | sec1 family domain containing 2 | 0.0481519 |
| SEC31A | SEC31 homolog A (S. cerevisiae) | 0.0478037 |
| LOX | lysyl oxidase | 0.0477734 |
| GLIS3 | GLIS family zinc finger 3 | 0.0463824 |
| TNS3 | tensin 3 | 0.0458946 |
| ITGA3 | integrin, alpha 3 (antigen CD49C, alpha 3 subunit of VLA-3 receptor) | 0.0443536 |
| ANKRD28 | ankyrin repeat domain 28 | 0.0439577 |
| FLNA | filamin A, alpha | 0.0439363 |
| SLC38A2 | solute carrier family 38, member 2 | 0.0436917 |
| AKAP9 | A kinase (PRKA) anchor protein 9 | 0.0435403 |
| TPM4 | tropomyosin 4 | 0.0434911 |
| PABPC1 | poly(A) binding protein, cytoplasmic 1 | 0.0430871 |
| PHLDA1 | pleckstrin homology-like domain, family A, member 1 | 0.04227 |
| GOLGB1 | golgin B1 | 0.0421427 |
| SRRM2 | serine/arginine repetitive matrix 2 | 0.0418644 |
| HDLBP | high density lipoprotein binding protein | 0.0418489 |
| ATXN1 | ataxin 1 | 0.0404861 |
| KDELR2 | KDEL (Lys-Asp-Glu-Leu) endoplasmic reticulum protein retention receptor 2 | 0.0399718 |
| BBS9 | Bardet-Biedl syndrome 9 | 0.0390408 |
| PTPRG | protein tyrosine phosphatase, receptor type, G | 0.0389316 |
| GARS1 | glycyl-tRNA synthetase 1 | 0.0388195 |
| ARHGEF2 | Rho/Rac guanine nucleotide exchange factor (GEF) 2 | 0.0387378 |
| MON2 | MON2 homolog (S. cerevisiae) | 0.0387269 |
| SLC2A1 | solute carrier family 2 (facilitated glucose transporter), member 1 | 0.0386127 |
| CALU | calumenin | 0.0383879 |
| PDLIM5 | PDZ and LIM domain 5 | 0.0379315 |
| SLC7A5 | solute carrier family 7 (amino acid transporter light chain, L system), member 5 | 0.0378496 |
| INHBA | inhibin, beta A | 0.0377628 |
| GNB1 | guanine nucleotide binding protein (G protein), beta polypeptide 1 | 0.0377333 |
| ANKIB1 | ankyrin repeat and IBR domain containing 1 | 0.0373399 |
| MGAT5 | mannosyl (alpha-1,6-)-glycoprotein beta-1,6-N-acetyl-glucosaminyltransferase | 0.0373266 |
| GANAB | glucosidase, alpha; neutral AB | 0.0363302 |
| ITGA5 | integrin, alpha 5 (fibronectin receptor, alpha polypeptide) | 0.0362361 |
| SDC4 | syndecan 4 | 0.0358745 |
| COL5A1 | collagen, type V, alpha 1 | 0.0357693 |
| PHF14 | PHD finger protein 14 | 0.0350975 |
| MACF1 | microtubule-actin crosslinking factor 1 | 0.0349463 |
| SPRED2 | sprouty-related, EVH1 domain containing 2 | 0.0347252 |
| COPA | coatomer protein complex, subunit alpha | 0.0346522 |
| FAM20C | family with sequence similarity 20, member C | 0.0342005 |
| EEF2 | eukaryotic translation elongation factor 2 | 0.0337343 |
| PRKCSH | protein kinase C substrate 80K-H | 0.033643 |
| RNF213 | ring finger protein 213 | 0.0330371 |
| PPFIBP1 | PTPRF interacting protein, binding protein 1 (liprin beta 1) | 0.0329443 |
| HLA-A | major histocompatibility complex, class I, A | 0.0325217 |
| KPNA4 | karyopherin alpha 4 (importin alpha 3) | 0.0325144 |
| FSCN1 | fascin actin-bundling protein 1 | 0.0324449 |
| GRB10 | growth factor receptor-bound protein 10 | 0.0322529 |
| MYH9 | myosin, heavy chain 9, non-muscle | 0.0321178 |
| USP47 | ubiquitin specific peptidase 47 | 0.0320375 |
| ATM | ATM serine/threonine kinase | 0.0316988 |
| ARIH1 | ariadne RBR E3 ubiquitin protein ligase 1 | 0.0313166 |
| SMC5 | structural maintenance of chromosomes 5 | 0.031111 |
| USP36 | ubiquitin specific peptidase 36 | 0.0303471 |
| GOLGA2 | golgin A2 | 0.0303317 |
| SERPINH1 | serpin peptidase inhibitor, clade H (heat shock protein 47), member 1, (collagen binding protein 1) | 0.0302618 |
| Symbol | Name | Standardized Value |
|---|---|---|
| MT2A | metallothionein 2A | -0.0781732 |
| NALF1 | NALCN channel auxiliary factor 1 | -0.0772655 |
| HNRNPA2B1 | heterogeneous nuclear ribonucleoprotein A2/B1 | -0.0719606 |
| SDK1 | sidekick cell adhesion molecule 1 | -0.0657143 |
| DTNA | dystrobrevin, alpha | -0.0600014 |
| PTMA | prothymosin, alpha | -0.0563961 |
| PLOD2 | procollagen-lysine, 2-oxoglutarate 5-dioxygenase 2 | -0.0559056 |
| NPM1 | nucleophosmin (nucleolar phosphoprotein B23, numatrin) | -0.048859 |
| ERO1A | endoplasmic reticulum oxidoreductase 1 alpha | -0.0440508 |
| GBE1 | glucan (1,4-alpha-), branching enzyme 1 | -0.0437748 |
| HSP90AA1 | heat shock protein 90kDa alpha (cytosolic), class A member 1 | -0.0436214 |
| RPS2 | ribosomal protein S2 | -0.0363716 |
| RPS23 | ribosomal protein S23 | -0.0330639 |
| ITGA2 | integrin, alpha 2 (CD49B, alpha 2 subunit of VLA-2 receptor) | -0.0325075 |
| RPS8 | ribosomal protein S8 | -0.0322416 |
| NAP1L1 | nucleosome assembly protein 1-like 1 | -0.0297252 |
| HNRNPU | heterogeneous nuclear ribonucleoprotein U (scaffold attachment factor A) | -0.0292962 |
| SERPINE1 | serpin peptidase inhibitor, clade E (nexin, plasminogen activator inhibitor type 1), member 1 | -0.0287124 |
| IGF2 | insulin-like growth factor 2 | -0.0286576 |
| CCND1 | cyclin D1 | -0.0285159 |
| RPL38 | ribosomal protein L38 | -0.0282465 |
| RPLP1 | ribosomal protein, large, P1 | -0.0281206 |
| IQCJ-SCHIP1 | IQCJ-SCHIP1 readthrough | -0.0276477 |
| PDE4D | phosphodiesterase 4D, cAMP-specific | -0.0276467 |
| CALM2 | calmodulin 2 (phosphorylase kinase, delta) | -0.0256353 |
| RPL31 | ribosomal protein L31 | -0.0253861 |
| RPS6 | ribosomal protein S6 | -0.0253067 |
| RPL37A | ribosomal protein L37a | -0.0244961 |
| ZNF804A | zinc finger protein 804A | -0.0243139 |
| RPS25 | ribosomal protein S25 | -0.0240322 |
| NRXN3 | neurexin 3 | -0.0240119 |
| KCTD16 | potassium channel tetramerization domain containing 16 | -0.0235898 |
| NUCKS1 | nuclear casein kinase and cyclin-dependent kinase substrate 1 | -0.0235374 |
| P4HA1 | prolyl 4-hydroxylase, alpha polypeptide I | -0.0233438 |
| STXBP1 | syntaxin binding protein 1 | -0.0232122 |
| MATR3 | matrin 3 | -0.0231603 |
| RPL9 | ribosomal protein L9 | -0.023065 |
| UBA2 | ubiquitin-like modifier activating enzyme 2 | -0.0226048 |
| KDM3A | lysine (K)-specific demethylase 3A | -0.0224352 |
| RPS24 | ribosomal protein S24 | -0.0222994 |
| MXI1 | MAX interactor 1, dimerization protein | -0.0221756 |
| RPS17 | ribosomal protein S17 | -0.0211028 |
| PRKDC | protein kinase, DNA-activated, catalytic polypeptide | -0.0208692 |
| ITGB3BP | integrin beta 3 binding protein (beta3-endonexin) | -0.0208638 |
| UPP1 | uridine phosphorylase 1 | -0.0208228 |
| RPL7 | ribosomal protein L7 | -0.0207961 |
| NAMPT | nicotinamide phosphoribosyltransferase | -0.0207378 |
| LUC7L3 | LUC7-like 3 (S. cerevisiae) | -0.0205202 |
| RPS27A | ribosomal protein S27a | -0.0204243 |
| RPL34 | ribosomal protein L34 | -0.0202735 |
| RPL12 | ribosomal protein L12 | -0.0202598 |
| XPO1 | exportin 1 | -0.0199993 |
| PTK2 | protein tyrosine kinase 2 | -0.0196759 |
| RPS29 | ribosomal protein S29 | -0.0196149 |
| RPL19 | ribosomal protein L19 | -0.0192627 |
| RPLP2 | ribosomal protein, large, P2 | -0.0192488 |
| HMGA2 | high mobility group AT-hook 2 | -0.0188233 |
| STC1 | stanniocalcin 1 | -0.0187274 |
| ITGB1 | integrin, beta 1 (fibronectin receptor, beta polypeptide, antigen CD29 includes MDF2, MSK12) | -0.0184009 |
| SLC5A3 | solute carrier family 5 (sodium/myo-inositol cotransporter), member 3 | -0.0183855 |
| ADM | adrenomedullin | -0.0183751 |
| KTN1 | kinectin 1 (kinesin receptor) | -0.0181468 |
| H1-4 | H1.4 linker histone, cluster member | -0.0180538 |
| FMNL2 | formin-like 2 | -0.0179764 |
| WWOX | WW domain containing oxidoreductase | -0.0177464 |
| VEGFA | vascular endothelial growth factor A | -0.0176836 |
| HIP1 | huntingtin interacting protein 1 | -0.0176172 |
| CFAP96 | cilia and flagella associated protein 96 | -0.0175525 |
| WSB1 | WD repeat and SOCS box containing 1 | -0.0174942 |
| RPS13 | ribosomal protein S13 | -0.01737 |
| SMG1 | SMG1 phosphatidylinositol 3-kinase-related kinase | -0.0172711 |
| SOX5 | SRY (sex determining region Y)-box 5 | -0.0170886 |
| PTGS2 | prostaglandin-endoperoxide synthase 2 (prostaglandin G/H synthase and cyclooxygenase) | -0.0169173 |
| IFIT2 | interferon-induced protein with tetratricopeptide repeats 2 | -0.0167607 |
| NASP | nuclear autoantigenic sperm protein (histone-binding) | -0.0164434 |
| PPIB | peptidylprolyl isomerase B (cyclophilin B) | -0.01644 |
| CTDSPL2 | CTD (carboxy-terminal domain, RNA polymerase II, polypeptide A) small phosphatase like 2 | -0.0163589 |
| HIVEP2 | human immunodeficiency virus type I enhancer binding protein 2 | -0.016008 |
| HNRNPR | heterogeneous nuclear ribonucleoprotein R | -0.0158351 |
| ZBTB1 | zinc finger and BTB domain containing 1 | -0.0158156 |
| ANLN | anillin, actin binding protein | -0.015577 |
| EIF4A2 | eukaryotic translation initiation factor 4A2 | -0.0155075 |
| MAP3K2 | mitogen-activated protein kinase kinase kinase 2 | -0.0154791 |
| RPL32 | ribosomal protein L32 | -0.0153906 |
| PITPNC1 | phosphatidylinositol transfer protein, cytoplasmic 1 | -0.01535 |
| CHD1L | chromodomain helicase DNA binding protein 1-like | -0.0152546 |
| RPL18 | ribosomal protein L18 | -0.015201 |
| EEF1A1 | eukaryotic translation elongation factor 1 alpha 1 | -0.0151773 |
| PLAUR | plasminogen activator, urokinase receptor | -0.0151684 |
| PHIP | pleckstrin homology domain interacting protein | -0.01516 |
| NLGN1 | neuroligin 1 | -0.0151078 |
| RPL26 | ribosomal protein L26 | -0.0150202 |
| UGP2 | UDP-glucose pyrophosphorylase 2 | -0.0148878 |
| ELF2 | E74-like factor 2 (ets domain transcription factor) | -0.0148282 |
| DNAJA1 | DnaJ (Hsp40) homolog, subfamily A, member 1 | -0.0147797 |
| HSD17B12 | hydroxysteroid (17-beta) dehydrogenase 12 | -0.0147342 |
| DEK | DEK proto-oncogene | -0.0146977 |
| TMSB10 | thymosin beta 10 | -0.0146923 |
| HNRNPH1 | heterogeneous nuclear ribonucleoprotein H1 (H) | -0.0145522 |
| ARPP19 | cAMP-regulated phosphoprotein, 19kDa | -0.0145267 |
