| Dataset | Tahoe Therapeutics Tahoe 100M Perturbation Atlas |
| Category | transcriptomics |
| Type | cell type |
| Description | Esmolol (hydrochloride) perturbation in J82 cell line (Tahoe Therapeutics) |
| Similar Terms | |
| Downloads & Tools |
200 genes differentially expressed following the Esmolol (hydrochloride)_J82 drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| FTH1 | ferritin, heavy polypeptide 1 | 0.118799 |
| GAPDH | glyceraldehyde-3-phosphate dehydrogenase | 0.114124 |
| HLA-B | major histocompatibility complex, class I, B | 0.108527 |
| ZNF841 | zinc finger protein 841 | 0.107652 |
| SLC12A8 | solute carrier family 12, member 8 | 0.100822 |
| INTS6 | integrator complex subunit 6 | 0.0958296 |
| MYH9 | myosin, heavy chain 9, non-muscle | 0.0878538 |
| COL5A1 | collagen, type V, alpha 1 | 0.081355 |
| HLA-A | major histocompatibility complex, class I, A | 0.077752 |
| FLNA | filamin A, alpha | 0.075855 |
| PALM2AKAP2 | PALM2 and AKAP2 fusion | 0.0721518 |
| GBE1 | glucan (1,4-alpha-), branching enzyme 1 | 0.0717672 |
| ZSWIM6 | zinc finger, SWIM-type containing 6 | 0.0653261 |
| RPS6 | ribosomal protein S6 | 0.0643867 |
| TLE4 | transducin-like enhancer of split 4 | 0.0633781 |
| PRRC2A | proline-rich coiled-coil 2A | 0.0622038 |
| SLIT2 | slit homolog 2 (Drosophila) | 0.0565255 |
| SMAD3 | SMAD family member 3 | 0.0536805 |
| MICAL2 | microtubule associated monooxygenase, calponin and LIM domain containing 2 | 0.0530792 |
| ACTG1 | actin gamma 1 | 0.0528575 |
| CD44 | CD44 molecule (Indian blood group) | 0.0524284 |
| PDLIM5 | PDZ and LIM domain 5 | 0.0523811 |
| P4HB | prolyl 4-hydroxylase, beta polypeptide | 0.0519974 |
| EXT1 | exostosin glycosyltransferase 1 | 0.0502396 |
| ASPH | aspartate beta-hydroxylase | 0.0502379 |
| VCL | vinculin | 0.0491537 |
| RAD51B | RAD51 paralog B | 0.0482044 |
| NAV2 | neuron navigator 2 | 0.0477773 |
| LOC112694756 | uncharaterized LOC112694756 | 0.0466451 |
| ACTN1 | actinin, alpha 1 | 0.0461396 |
| ITGA3 | integrin, alpha 3 (antigen CD49C, alpha 3 subunit of VLA-3 receptor) | 0.0456775 |
| L1CAM | L1 cell adhesion molecule | 0.045441 |
| FNDC3B | fibronectin type III domain containing 3B | 0.0431251 |
| GALNT18 | polypeptide N-acetylgalactosaminyltransferase 18 | 0.0419744 |
| COL7A1 | collagen, type VII, alpha 1 | 0.0409777 |
| SRRM2 | serine/arginine repetitive matrix 2 | 0.0409265 |
| EGFR | epidermal growth factor receptor | 0.0406743 |
| LPP | LIM domain containing preferred translocation partner in lipoma | 0.04058 |
| APLP2 | amyloid beta (A4) precursor-like protein 2 | 0.0400583 |
| GOLGB1 | golgin B1 | 0.039213 |
| TENM3 | teneurin transmembrane protein 3 | 0.0384995 |
| LENG8 | leukocyte receptor cluster (LRC) member 8 | 0.0375815 |
| FLNB | filamin B, beta | 0.037483 |
| DST | dystonin | 0.0370015 |
| ATXN1 | ataxin 1 | 0.0360579 |
| ZNF432 | zinc finger protein 432 | 0.035863 |
| E2F3 | E2F transcription factor 3 | 0.0358594 |
| PHACTR1 | phosphatase and actin regulator 1 | 0.0355427 |
| SHB | Src homology 2 domain containing adaptor protein B | 0.0353647 |
| PODXL | podocalyxin-like | 0.0353617 |
| VEGFC | vascular endothelial growth factor C | 0.0351522 |
| SEMA5A | sema domain, seven thrombospondin repeats (type 1 and type 1-like), transmembrane domain (TM) and short cytoplasmic domain, (semaphorin) 5A | 0.0347716 |
| MSN | moesin | 0.0344271 |
| NCOR2 | nuclear receptor corepressor 2 | 0.0343382 |
| MBNL1 | muscleblind-like splicing regulator 1 | 0.0343327 |
| NALF1 | NALCN channel auxiliary factor 1 | 0.0338586 |
| GNB1 | guanine nucleotide binding protein (G protein), beta polypeptide 1 | 0.0335586 |
| MCL1 | myeloid cell leukemia 1 | 0.0328241 |
| HUWE1 | HECT, UBA and WWE domain containing 1, E3 ubiquitin protein ligase | 0.0326829 |
| RALY | RALY heterogeneous nuclear ribonucleoprotein | 0.0322821 |
| SPOCK1 | sparc/osteonectin, cwcv and kazal-like domains proteoglycan (testican) 1 | 0.0322571 |
| RPL37 | ribosomal protein L37 | 0.0321408 |
| LRMDA | leucine rich melanocyte differentiation associated | 0.0321052 |
| ASXL1 | additional sex combs like transcriptional regulator 1 | 0.0320089 |
| GLIS3 | GLIS family zinc finger 3 | 0.0316226 |
| ENO1 | enolase 1, (alpha) | 0.0313735 |
| HEG1 | heart development protein with EGF-like domains 1 | 0.0313531 |
| ZHX2 | zinc fingers and homeoboxes 2 | 0.0312465 |
| NAV1 | neuron navigator 1 | 0.0311185 |
| ZBTB20 | zinc finger and BTB domain containing 20 | 0.0307087 |
| TLN1 | talin 1 | 0.0305722 |
| PTPRG | protein tyrosine phosphatase, receptor type, G | 0.0303131 |
| POTEF | POTE ankyrin domain family, member F | 0.0301828 |
| EIF4G1 | eukaryotic translation initiation factor 4 gamma, 1 | 0.0298732 |
| STARD13 | StAR-related lipid transfer (START) domain containing 13 | 0.0298102 |
| SPTAN1 | spectrin, alpha, non-erythrocytic 1 | 0.0294342 |
| RUNX1 | runt-related transcription factor 1 | 0.029132 |
| RPL28 | ribosomal protein L28 | 0.0289616 |
| SPTBN1 | spectrin, beta, non-erythrocytic 1 | 0.0282919 |
| RPS2 | ribosomal protein S2 | 0.0282066 |
| ADARB1 | adenosine deaminase, RNA-specific, B1 | 0.0279888 |
| HIVEP3 | human immunodeficiency virus type I enhancer binding protein 3 | 0.0278312 |
| IQCJ-SCHIP1 | IQCJ-SCHIP1 readthrough | 0.0276194 |
| KDM4C | lysine (K)-specific demethylase 4C | 0.0274113 |
| HNRNPC | heterogeneous nuclear ribonucleoprotein C (C1/C2) | 0.0271488 |
| EEFSEC | eukaryotic elongation factor, selenocysteine-tRNA-specific | 0.0270653 |
| SEMA3C | sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3C | 0.0270204 |
| ARGLU1 | arginine and glutamate rich 1 | 0.0269869 |
| DTNA | dystrobrevin, alpha | 0.0269296 |
| COL27A1 | collagen, type XXVII, alpha 1 | 0.0267576 |
| SET | SET nuclear proto-oncogene | 0.0266559 |
| MYO1E | myosin IE | 0.0266051 |
| HSPA8 | heat shock 70kDa protein 8 | 0.0265148 |
| CD59 | CD59 molecule, complement regulatory protein | 0.0264657 |
| VMP1 | vacuole membrane protein 1 | 0.0264371 |
| RPS12 | ribosomal protein S12 | 0.0263181 |
| DOCK5 | dedicator of cytokinesis 5 | 0.0262734 |
| TCIM | transcriptional and immune response regulator | 0.0261791 |
| SEPTIN9 | septin 9 | 0.0260966 |
| BRIP1 | BRCA1 interacting protein C-terminal helicase 1 | 0.0260626 |
| Symbol | Name | Standardized Value |
|---|---|---|
| FTL | ferritin, light polypeptide | -0.199677 |
| SERPINE1 | serpin peptidase inhibitor, clade E (nexin, plasminogen activator inhibitor type 1), member 1 | -0.143892 |
| TXNRD1 | thioredoxin reductase 1 | -0.125865 |
| IGFBP3 | insulin-like growth factor binding protein 3 | -0.106407 |
| UGCG | UDP-glucose ceramide glucosyltransferase | -0.105655 |
| YWHAZ | tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, zeta | -0.0839449 |
| MARCKS | myristoylated alanine-rich protein kinase C substrate | -0.0830424 |
| TMSB10 | thymosin beta 10 | -0.0797798 |
| ABI3BP | ABI family, member 3 (NESH) binding protein | -0.0721774 |
| DLG1 | discs, large homolog 1 (Drosophila) | -0.0709301 |
| MT1X | metallothionein 1X | -0.0707525 |
| F3 | coagulation factor III (thromboplastin, tissue factor) | -0.0614772 |
| HSPA5 | heat shock 70kDa protein 5 (glucose-regulated protein, 78kDa) | -0.0604781 |
| FN1 | fibronectin 1 | -0.053401 |
| RBPJ | recombination signal binding protein for immunoglobulin kappa J region | -0.0505828 |
| ABCA1 | ATP-binding cassette, sub-family A (ABC1), member 1 | -0.048226 |
| MT2A | metallothionein 2A | -0.0478398 |
| NDRG1 | N-myc downstream regulated 1 | -0.0474258 |
| CALR | calreticulin | -0.0465957 |
| NUCKS1 | nuclear casein kinase and cyclin-dependent kinase substrate 1 | -0.0453998 |
| AHNAK | AHNAK nucleoprotein | -0.0427876 |
| MATR3 | matrin 3 | -0.0419284 |
| NPEPPS | aminopeptidase puromycin sensitive | -0.0413412 |
| NAMPT | nicotinamide phosphoribosyltransferase | -0.0411429 |
| VIM | vimentin | -0.040903 |
| TMSB4X | thymosin beta 4, X-linked | -0.0406517 |
| PLOD2 | procollagen-lysine, 2-oxoglutarate 5-dioxygenase 2 | -0.0406066 |
| KPNB1 | karyopherin (importin) beta 1 | -0.0393039 |
| PTMA | prothymosin, alpha | -0.0389431 |
| SF3B2 | splicing factor 3b, subunit 2, 145kDa | -0.0382418 |
| AKAP12 | A kinase (PRKA) anchor protein 12 | -0.0382045 |
| NUP58 | nucleoporin 58 | -0.0373191 |
| PDS5B | PDS5 cohesin associated factor B | -0.0359744 |
| RNF168 | ring finger protein 168, E3 ubiquitin protein ligase | -0.0359141 |
| LMAN1 | lectin, mannose-binding, 1 | -0.0357996 |
| CALM2 | calmodulin 2 (phosphorylase kinase, delta) | -0.0354943 |
| JUN | jun proto-oncogene | -0.0354696 |
| RPL35A | ribosomal protein L35a | -0.0351522 |
| SOD2 | superoxide dismutase 2, mitochondrial | -0.0351397 |
| PLK2 | polo-like kinase 2 | -0.0351058 |
| PLCB4 | phospholipase C, beta 4 | -0.0344486 |
| ADAM9 | ADAM metallopeptidase domain 9 | -0.0344205 |
| ERO1A | endoplasmic reticulum oxidoreductase 1 alpha | -0.0341419 |
| SPAG9 | sperm associated antigen 9 | -0.0324279 |
| PKM | pyruvate kinase, muscle | -0.032374 |
| TPX2 | TPX2, microtubule-associated | -0.0319707 |
| SLC25A36 | solute carrier family 25 (pyrimidine nucleotide carrier), member 36 | -0.0318429 |
| DEK | DEK proto-oncogene | -0.0315972 |
| CCND1 | cyclin D1 | -0.0314675 |
| PSIP1 | PC4 and SFRS1 interacting protein 1 | -0.0313123 |
| HNRNPU | heterogeneous nuclear ribonucleoprotein U (scaffold attachment factor A) | -0.0302675 |
| SMURF2 | SMAD specific E3 ubiquitin protein ligase 2 | -0.0301065 |
| PLIN2 | perilipin 2 | -0.0296557 |
| ADAMTS6 | ADAM metallopeptidase with thrombospondin type 1 motif, 6 | -0.0287745 |
| GOLGA4 | golgin A4 | -0.0285513 |
| TPD52 | tumor protein D52 | -0.0283017 |
| TKT | transketolase | -0.0278641 |
| RIOK3 | RIO kinase 3 | -0.0275115 |
| ETS1 | v-ets avian erythroblastosis virus E26 oncogene homolog 1 | -0.0267937 |
| MARCHF6 | membrane associated ring-CH-type finger 6 | -0.02656 |
| GNB4 | guanine nucleotide binding protein (G protein), beta polypeptide 4 | -0.0264499 |
| AP3B1 | adaptor-related protein complex 3, beta 1 subunit | -0.026363 |
| RAB6A | RAB6A, member RAS oncogene family | -0.0263556 |
| CTSD | cathepsin D | -0.0262103 |
| XPO1 | exportin 1 | -0.0259536 |
| TPM4 | tropomyosin 4 | -0.0258696 |
| CDK6 | cyclin-dependent kinase 6 | -0.0253356 |
| NIPBL | Nipped-B homolog (Drosophila) | -0.0252036 |
| ZFP36L1 | ZFP36 ring finger protein-like 1 | -0.0251211 |
| CCDC80 | coiled-coil domain containing 80 | -0.02508 |
| CBX3 | chromobox homolog 3 | -0.0250748 |
| ADM | adrenomedullin | -0.0249499 |
| CANX | calnexin | -0.0248001 |
| HIF1A | hypoxia inducible factor 1, alpha subunit (basic helix-loop-helix transcription factor) | -0.0247956 |
| TUBB | tubulin, beta class I | -0.0247789 |
| IPO7 | importin 7 | -0.0247172 |
| MAP4K5 | mitogen-activated protein kinase kinase kinase kinase 5 | -0.0245363 |
| CENPF | centromere protein F, 350/400kDa | -0.0241563 |
| HNRNPH1 | heterogeneous nuclear ribonucleoprotein H1 (H) | -0.0240334 |
| PGK1 | phosphoglycerate kinase 1 | -0.0239124 |
| CCNL1 | cyclin L1 | -0.023419 |
| CALM1 | calmodulin 1 (phosphorylase kinase, delta) | -0.0228756 |
| CAPZA1 | capping protein (actin filament) muscle Z-line, alpha 1 | -0.0226643 |
| POSTN | periostin, osteoblast specific factor | -0.0222598 |
| INSIG2 | insulin induced gene 2 | -0.0222207 |
| CKAP5 | cytoskeleton associated protein 5 | -0.0220889 |
| YWHAB | tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, beta | -0.0220184 |
| UBE2V1 | ubiquitin-conjugating enzyme E2 variant 1 | -0.0219319 |
| MAP3K2 | mitogen-activated protein kinase kinase kinase 2 | -0.0218513 |
| RPS24 | ribosomal protein S24 | -0.0218252 |
| KDM3A | lysine (K)-specific demethylase 3A | -0.0216754 |
| RBM25 | RNA binding motif protein 25 | -0.0215334 |
| EIF4A1 | eukaryotic translation initiation factor 4A1 | -0.0211914 |
| RRBP1 | ribosome binding protein 1 | -0.0210252 |
| GAPVD1 | GTPase activating protein and VPS9 domains 1 | -0.0210065 |
| TOP2B | topoisomerase (DNA) II beta 180kDa | -0.0208118 |
| PLEKHB2 | pleckstrin homology domain containing, family B (evectins) member 2 | -0.0207978 |
| RBM39 | RNA binding motif protein 39 | -0.0207765 |
| WDR45B | WD repeat domain 45B | -0.0207213 |
| MXI1 | MAX interactor 1, dimerization protein | -0.0207172 |
