| Dataset | Tahoe Therapeutics Tahoe 100M Perturbation Atlas |
| Category | transcriptomics |
| Type | cell type |
| Description | Esmolol (hydrochloride) perturbation in LOX-IMVI cell line (Tahoe Therapeutics) |
| Similar Terms | |
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200 genes differentially expressed following the Esmolol (hydrochloride)_LOX-IMVI drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| GAPDH | glyceraldehyde-3-phosphate dehydrogenase | 0.0870504 |
| PPP3CA | protein phosphatase 3, catalytic subunit, alpha isozyme | 0.0514703 |
| EGR1 | early growth response 1 | 0.0476865 |
| YBX3 | Y box binding protein 3 | 0.0453831 |
| H1-0 | H1.0 linker histone | 0.0429158 |
| PABPC1 | poly(A) binding protein, cytoplasmic 1 | 0.0404979 |
| RPS2 | ribosomal protein S2 | 0.0386365 |
| RUNX1 | runt-related transcription factor 1 | 0.0373641 |
| CD109 | CD109 molecule | 0.0355876 |
| RPS6 | ribosomal protein S6 | 0.0349319 |
| UGCG | UDP-glucose ceramide glucosyltransferase | 0.0319847 |
| SERPINE1 | serpin peptidase inhibitor, clade E (nexin, plasminogen activator inhibitor type 1), member 1 | 0.0316134 |
| SMAD3 | SMAD family member 3 | 0.0314842 |
| CCN2 | cellular communication network factor 2 | 0.0313376 |
| VCL | vinculin | 0.0295735 |
| MSN | moesin | 0.0293095 |
| EPB41L2 | erythrocyte membrane protein band 4.1-like 2 | 0.0269874 |
| NEDD4L | neural precursor cell expressed, developmentally down-regulated 4-like, E3 ubiquitin protein ligase | 0.0263521 |
| FRMD6 | FERM domain containing 6 | 0.0257373 |
| PFN1 | profilin 1 | 0.0254408 |
| TRIO | trio Rho guanine nucleotide exchange factor | 0.0246627 |
| KPNA4 | karyopherin alpha 4 (importin alpha 3) | 0.0246408 |
| ATP13A3 | ATPase type 13A3 | 0.0246285 |
| PRRC2A | proline-rich coiled-coil 2A | 0.0244886 |
| RPL28 | ribosomal protein L28 | 0.0241301 |
| RPL21 | ribosomal protein L21 | 0.0233802 |
| ADAM9 | ADAM metallopeptidase domain 9 | 0.0223773 |
| SRRM2 | serine/arginine repetitive matrix 2 | 0.0212141 |
| REV3L | REV3-like, polymerase (DNA directed), zeta, catalytic subunit | 0.0212057 |
| TANC2 | tetratricopeptide repeat, ankyrin repeat and coiled-coil containing 2 | 0.0209235 |
| ARID1A | AT rich interactive domain 1A (SWI-like) | 0.0207932 |
| FTH1 | ferritin, heavy polypeptide 1 | 0.0207842 |
| KLF7 | Kruppel-like factor 7 (ubiquitous) | 0.020592 |
| CD163L1 | CD163 molecule-like 1 | 0.0204138 |
| ADAM19 | ADAM metallopeptidase domain 19 | 0.0192209 |
| NABP1 | nucleic acid binding protein 1 | 0.0190931 |
| HILPDA | hypoxia inducible lipid droplet-associated | 0.018805 |
| TNNC1 | troponin C type 1 (slow) | 0.0187568 |
| CTSB | cathepsin B | 0.0182994 |
| RNF145 | ring finger protein 145 | 0.0179464 |
| ANKRD28 | ankyrin repeat domain 28 | 0.0178689 |
| MMP12 | matrix metallopeptidase 12 | 0.0178513 |
| HSPA8 | heat shock 70kDa protein 8 | 0.0178201 |
| RIGI | RNA sensor RIG-I | 0.0175487 |
| TSC22D2 | TSC22 domain family, member 2 | 0.0172007 |
| CHST11 | carbohydrate (chondroitin 4) sulfotransferase 11 | 0.017101 |
| MIDEAS | mitotic deacetylase associated SANT domain protein | 0.0166962 |
| HP1BP3 | heterochromatin protein 1, binding protein 3 | 0.0165278 |
| DST | dystonin | 0.0165081 |
| SETD5 | SET domain containing 5 | 0.0163151 |
| RPL13A | ribosomal protein L13a | 0.0162842 |
| FOSL1 | FOS-like antigen 1 | 0.0162321 |
| GPC6 | glypican 6 | 0.015968 |
| BCAR3 | breast cancer anti-estrogen resistance 3 | 0.0158321 |
| PPFIBP1 | PTPRF interacting protein, binding protein 1 (liprin beta 1) | 0.0158256 |
| SMURF2 | SMAD specific E3 ubiquitin protein ligase 2 | 0.0155183 |
| BHLHE40 | basic helix-loop-helix family, member e40 | 0.0154825 |
| PTBP3 | polypyrimidine tract binding protein 3 | 0.015311 |
| BRD2 | bromodomain containing 2 | 0.0151263 |
| ALCAM | activated leukocyte cell adhesion molecule | 0.0150689 |
| COL6A2 | collagen, type VI, alpha 2 | 0.0150455 |
| LOC102724023 | ES1 protein homolog, mitochondrial | 0.0150113 |
| JMJD1C | jumonji domain containing 1C | 0.0148746 |
| PAWR | PRKC, apoptosis, WT1, regulator | 0.0147568 |
| NLGN1 | neuroligin 1 | 0.0147497 |
| CD44 | CD44 molecule (Indian blood group) | 0.014711 |
| WDR43 | WD repeat domain 43 | 0.0146749 |
| NAMPT | nicotinamide phosphoribosyltransferase | 0.0146519 |
| ACTN1 | actinin, alpha 1 | 0.0146179 |
| AXL | AXL receptor tyrosine kinase | 0.0142073 |
| HSPG2 | heparan sulfate proteoglycan 2 | 0.0141792 |
| ASXL1 | additional sex combs like transcriptional regulator 1 | 0.0140373 |
| ERBIN | erbb2 interacting protein | 0.0140372 |
| HAS2 | hyaluronan synthase 2 | 0.0139789 |
| FNDC3B | fibronectin type III domain containing 3B | 0.0137586 |
| NFKBIZ | nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor, zeta | 0.0137505 |
| CDK17 | cyclin-dependent kinase 17 | 0.0136882 |
| SLC2A1 | solute carrier family 2 (facilitated glucose transporter), member 1 | 0.0136829 |
| GPBP1 | GC-rich promoter binding protein 1 | 0.0136293 |
| CITED2 | Cbp/p300-interacting transactivator, with Glu/Asp-rich carboxy-terminal domain, 2 | 0.013585 |
| DHX15 | DEAH (Asp-Glu-Ala-His) box helicase 15 | 0.0135656 |
| LENG8 | leukocyte receptor cluster (LRC) member 8 | 0.0132955 |
| KMT2C | lysine (K)-specific methyltransferase 2C | 0.0132622 |
| QKI | QKI, KH domain containing, RNA binding | 0.0131741 |
| ADM | adrenomedullin | 0.0129346 |
| SMG6 | SMG6 nonsense mediated mRNA decay factor | 0.0128906 |
| GLIPR1 | GLI pathogenesis-related 1 | 0.0126865 |
| SHC1 | SHC (Src homology 2 domain containing) transforming protein 1 | 0.0125437 |
| NFATC2 | nuclear factor of activated T-cells, cytoplasmic, calcineurin-dependent 2 | 0.0125379 |
| KLF6 | Kruppel-like factor 6 | 0.012533 |
| ETV6 | ets variant 6 | 0.0124251 |
| RPL27 | ribosomal protein L27 | 0.0123901 |
| ZNF292 | zinc finger protein 292 | 0.0122486 |
| HELZ | helicase with zinc finger | 0.0121186 |
| NCOR2 | nuclear receptor corepressor 2 | 0.0120206 |
| IFIT2 | interferon-induced protein with tetratricopeptide repeats 2 | 0.0117229 |
| BCLAF1 | BCL2-associated transcription factor 1 | 0.0116502 |
| FOSB | FBJ murine osteosarcoma viral oncogene homolog B | 0.0116138 |
| KMT2D | lysine (K)-specific methyltransferase 2D | 0.0116046 |
| SIK3 | SIK family kinase 3 | 0.0115979 |
| Symbol | Name | Standardized Value |
|---|---|---|
| VIM | vimentin | -0.307605 |
| TMSB10 | thymosin beta 10 | -0.145606 |
| HSP90B1 | heat shock protein 90kDa beta (Grp94), member 1 | -0.142907 |
| AHNAK | AHNAK nucleoprotein | -0.122558 |
| HSPA5 | heat shock 70kDa protein 5 (glucose-regulated protein, 78kDa) | -0.114335 |
| RPS27A | ribosomal protein S27a | -0.0961713 |
| NPM1 | nucleophosmin (nucleolar phosphoprotein B23, numatrin) | -0.0873445 |
| RPL23 | ribosomal protein L23 | -0.081411 |
| HSP90AB1 | heat shock protein 90kDa alpha (cytosolic), class B member 1 | -0.0798798 |
| ASPH | aspartate beta-hydroxylase | -0.0752111 |
| PLOD2 | procollagen-lysine, 2-oxoglutarate 5-dioxygenase 2 | -0.0730932 |
| UBC | ubiquitin C | -0.0722664 |
| PTMA | prothymosin, alpha | -0.070288 |
| AKAP12 | A kinase (PRKA) anchor protein 12 | -0.0679877 |
| EFNA5 | ephrin-A5 | -0.064841 |
| NAP1L1 | nucleosome assembly protein 1-like 1 | -0.0593958 |
| RPL31 | ribosomal protein L31 | -0.0556752 |
| EXT1 | exostosin glycosyltransferase 1 | -0.0546204 |
| DTNA | dystrobrevin, alpha | -0.0541038 |
| RPLP1 | ribosomal protein, large, P1 | -0.0540282 |
| PRKG1 | protein kinase, cGMP-dependent, type I | -0.05387 |
| HNRNPA2B1 | heterogeneous nuclear ribonucleoprotein A2/B1 | -0.0523613 |
| PKM | pyruvate kinase, muscle | -0.0521109 |
| RPS24 | ribosomal protein S24 | -0.0515429 |
| PHACTR1 | phosphatase and actin regulator 1 | -0.0514069 |
| LDHA | lactate dehydrogenase A | -0.0497891 |
| EEF2 | eukaryotic translation elongation factor 2 | -0.0497147 |
| CANX | calnexin | -0.0475954 |
| ENO1 | enolase 1, (alpha) | -0.0467845 |
| PGK1 | phosphoglycerate kinase 1 | -0.0443974 |
| KDM3A | lysine (K)-specific demethylase 3A | -0.043833 |
| RPL4 | ribosomal protein L4 | -0.0432604 |
| TM4SF1 | transmembrane 4 L six family member 1 | -0.0397033 |
| ADAMTS6 | ADAM metallopeptidase with thrombospondin type 1 motif, 6 | -0.0393592 |
| RPL35A | ribosomal protein L35a | -0.0393519 |
| TPT1 | tumor protein, translationally-controlled 1 | -0.0391761 |
| TEAD1 | TEA domain family member 1 (SV40 transcriptional enhancer factor) | -0.0369843 |
| SLC8A1 | solute carrier family 8 (sodium/calcium exchanger), member 1 | -0.0368426 |
| RPS17 | ribosomal protein S17 | -0.0358378 |
| CALM1 | calmodulin 1 (phosphorylase kinase, delta) | -0.0347151 |
| SAMD3 | sterile alpha motif domain containing 3 | -0.0345829 |
| FTL | ferritin, light polypeptide | -0.0331185 |
| ITGB1 | integrin, beta 1 (fibronectin receptor, beta polypeptide, antigen CD29 includes MDF2, MSK12) | -0.0328738 |
| CTNNA1 | catenin (cadherin-associated protein), alpha 1, 102kDa | -0.0328031 |
| SAMD4A | sterile alpha motif domain containing 4A | -0.0319372 |
| HSP90AA1 | heat shock protein 90kDa alpha (cytosolic), class A member 1 | -0.0318206 |
| PRKDC | protein kinase, DNA-activated, catalytic polypeptide | -0.0308955 |
| TAF15 | TAF15 RNA polymerase II, TATA box binding protein (TBP)-associated factor, 68kDa | -0.0308685 |
| ACTR2 | ARP2 actin-related protein 2 homolog (yeast) | -0.0305244 |
| HNRNPU | heterogeneous nuclear ribonucleoprotein U (scaffold attachment factor A) | -0.0303877 |
| TPM4 | tropomyosin 4 | -0.0303685 |
| CDH13 | cadherin 13 | -0.0303293 |
| USP34 | ubiquitin specific peptidase 34 | -0.0301503 |
| LIMS1 | LIM and senescent cell antigen-like domains 1 | -0.029394 |
| RPL34 | ribosomal protein L34 | -0.0293304 |
| RPL5 | ribosomal protein L5 | -0.0291443 |
| CDK6 | cyclin-dependent kinase 6 | -0.029095 |
| PNRC1 | proline-rich nuclear receptor coactivator 1 | -0.0286301 |
| YWHAZ | tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, zeta | -0.0275366 |
| RPS8 | ribosomal protein S8 | -0.0269187 |
| DNAJA1 | DnaJ (Hsp40) homolog, subfamily A, member 1 | -0.0265749 |
| PRKCE | protein kinase C, epsilon | -0.0260804 |
| RPS25 | ribosomal protein S25 | -0.0258667 |
| RPL7 | ribosomal protein L7 | -0.025582 |
| PCBP2 | poly(rC) binding protein 2 | -0.0253874 |
| CALR | calreticulin | -0.0253721 |
| CCT4 | chaperonin containing TCP1, subunit 4 (delta) | -0.0251985 |
| EEF1A1 | eukaryotic translation elongation factor 1 alpha 1 | -0.0249963 |
| SDCCAG8 | serologically defined colon cancer antigen 8 | -0.0249613 |
| MAPKAP1 | mitogen-activated protein kinase associated protein 1 | -0.0249083 |
| ZNF804A | zinc finger protein 804A | -0.0245003 |
| RPL37A | ribosomal protein L37a | -0.0241342 |
| EIF4G2 | eukaryotic translation initiation factor 4 gamma, 2 | -0.024096 |
| EIF4G3 | eukaryotic translation initiation factor 4 gamma, 3 | -0.023797 |
| LIMCH1 | LIM and calponin homology domains 1 | -0.0235808 |
| HNRNPK | heterogeneous nuclear ribonucleoprotein K | -0.0234849 |
| ASAP1 | ArfGAP with SH3 domain, ankyrin repeat and PH domain 1 | -0.022919 |
| EEF1D | eukaryotic translation elongation factor 1 delta (guanine nucleotide exchange protein) | -0.0225767 |
| CALU | calumenin | -0.0223964 |
| EIF1 | eukaryotic translation initiation factor 1 | -0.022389 |
| HNRNPH1 | heterogeneous nuclear ribonucleoprotein H1 (H) | -0.0223825 |
| DNAJC5 | DnaJ (Hsp40) homolog, subfamily C, member 5 | -0.0223611 |
| BIRC6 | baculoviral IAP repeat containing 6 | -0.0223391 |
| TAS2R14 | taste receptor, type 2, member 14 | -0.0223013 |
| CALM2 | calmodulin 2 (phosphorylase kinase, delta) | -0.0222401 |
| YWHAB | tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, beta | -0.0220945 |
| PTGES3 | prostaglandin E synthase 3 (cytosolic) | -0.0220842 |
| CCDC47 | coiled-coil domain containing 47 | -0.0217442 |
| DOCK4 | dedicator of cytokinesis 4 | -0.0216174 |
| AEBP2 | AE binding protein 2 | -0.0215547 |
| CCT8 | chaperonin containing TCP1, subunit 8 (theta) | -0.0214752 |
| DYNC1H1 | dynein, cytoplasmic 1, heavy chain 1 | -0.0214368 |
| SRGAP1 | SLIT-ROBO Rho GTPase activating protein 1 | -0.0208752 |
| PPP1CC | protein phosphatase 1, catalytic subunit, gamma isozyme | -0.020875 |
| DDX5 | DEAD (Asp-Glu-Ala-Asp) box helicase 5 | -0.0208452 |
| JUN | jun proto-oncogene | -0.0207761 |
| RPS4X | ribosomal protein S4, X-linked | -0.020566 |
| RACK1 | receptor for activated C kinase 1 | -0.0203831 |
| ITGA6 | integrin, alpha 6 | -0.0202259 |
| EIF4A2 | eukaryotic translation initiation factor 4A2 | -0.0196895 |
