| Dataset | Tahoe Therapeutics Tahoe 100M Perturbation Atlas |
| Category | transcriptomics |
| Type | cell type |
| Description | Esmolol (hydrochloride) perturbation in LS 180 cell line (Tahoe Therapeutics) |
| Similar Terms | |
| Downloads & Tools |
200 genes differentially expressed following the Esmolol (hydrochloride)_LS 180 drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| CEMIP | cell migration inducing protein, hyaluronan binding | 0.19886 |
| SLC12A2 | solute carrier family 12 (sodium/potassium/chloride transporter), member 2 | 0.187311 |
| TNS4 | tensin 4 | 0.179523 |
| FAT1 | FAT atypical cadherin 1 | 0.141937 |
| ITGA6 | integrin, alpha 6 | 0.120787 |
| FTH1 | ferritin, heavy polypeptide 1 | 0.1059 |
| SLC7A11 | solute carrier family 7 (anionic amino acid transporter light chain, xc- system), member 11 | 0.103074 |
| ANXA2 | annexin A2 | 0.101638 |
| MUC6 | mucin 6, oligomeric mucus/gel-forming | 0.0974819 |
| PABPC1 | poly(A) binding protein, cytoplasmic 1 | 0.0964988 |
| DSPP | dentin sialophosphoprotein | 0.0900418 |
| PTMA | prothymosin, alpha | 0.0897303 |
| KRT8 | keratin 8, type II | 0.0885398 |
| GAPDH | glyceraldehyde-3-phosphate dehydrogenase | 0.087693 |
| GPRC5A | G protein-coupled receptor, class C, group 5, member A | 0.0864484 |
| RNF43 | ring finger protein 43 | 0.0837682 |
| SPTBN1 | spectrin, beta, non-erythrocytic 1 | 0.0836137 |
| CADPS | Ca++-dependent secretion activator | 0.0820943 |
| ABHD2 | abhydrolase domain containing 2 | 0.0759375 |
| PRSS3 | protease, serine, 3 | 0.0757159 |
| H1-0 | H1.0 linker histone | 0.0749261 |
| KLF3 | Kruppel-like factor 3 (basic) | 0.0735694 |
| ATP1B1 | ATPase, Na+/K+ transporting, beta 1 polypeptide | 0.0710912 |
| TRIM2 | tripartite motif containing 2 | 0.0669168 |
| EEF2 | eukaryotic translation elongation factor 2 | 0.0668127 |
| LDHA | lactate dehydrogenase A | 0.0651813 |
| KRT18 | keratin 18, type I | 0.0619806 |
| GPHN | gephyrin | 0.0593314 |
| KIF5B | kinesin family member 5B | 0.0577422 |
| LMO7 | LIM domain 7 | 0.0554956 |
| MACF1 | microtubule-actin crosslinking factor 1 | 0.0554681 |
| ENO1 | enolase 1, (alpha) | 0.0552264 |
| TGFBR2 | transforming growth factor, beta receptor II (70/80kDa) | 0.0549012 |
| SERPINB1 | serpin peptidase inhibitor, clade B (ovalbumin), member 1 | 0.054901 |
| EZR | ezrin | 0.0547493 |
| CD46 | CD46 molecule, complement regulatory protein | 0.0538432 |
| KDM7A | lysine (K)-specific demethylase 7A | 0.0534485 |
| MUC5AC | mucin 5AC, oligomeric mucus/gel-forming | 0.0529587 |
| PTPRR | protein tyrosine phosphatase, receptor type, R | 0.052708 |
| YWHAZ | tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, zeta | 0.052649 |
| SLCO1B3 | solute carrier organic anion transporter family, member 1B3 | 0.0520212 |
| SLC2A1 | solute carrier family 2 (facilitated glucose transporter), member 1 | 0.0519679 |
| ACTN4 | actinin, alpha 4 | 0.0512905 |
| PPARG | peroxisome proliferator-activated receptor gamma | 0.0511415 |
| CD44 | CD44 molecule (Indian blood group) | 0.0511191 |
| ITPRID2 | ITPR interacting domain containing 2 | 0.0504168 |
| CDH17 | cadherin 17, LI cadherin (liver-intestine) | 0.0499123 |
| PGK1 | phosphoglycerate kinase 1 | 0.0496091 |
| CDC42BPA | CDC42 binding protein kinase alpha (DMPK-like) | 0.0491052 |
| SRRM2 | serine/arginine repetitive matrix 2 | 0.0485186 |
| PTBP3 | polypyrimidine tract binding protein 3 | 0.0482637 |
| TMEM45B | transmembrane protein 45B | 0.048247 |
| FHL2 | four and a half LIM domains 2 | 0.0477045 |
| PLAUR | plasminogen activator, urokinase receptor | 0.0471193 |
| ABHD17C | abhydrolase domain containing 17C | 0.0470189 |
| ARHGAP32 | Rho GTPase activating protein 32 | 0.0459571 |
| HSP90AB1 | heat shock protein 90kDa alpha (cytosolic), class B member 1 | 0.0457183 |
| UBE2H | ubiquitin-conjugating enzyme E2H | 0.0456881 |
| SCD | stearoyl-CoA desaturase (delta-9-desaturase) | 0.0450615 |
| NALF1 | NALCN channel auxiliary factor 1 | 0.0446819 |
| PRAG1 | PEAK1 related, kinase-activating pseudokinase 1 | 0.0445724 |
| ITGA2 | integrin, alpha 2 (CD49B, alpha 2 subunit of VLA-2 receptor) | 0.0441653 |
| EREG | epiregulin | 0.0438218 |
| TBC1D5 | TBC1 domain family, member 5 | 0.0435524 |
| USP6NL | USP6 N-terminal like | 0.0431462 |
| PHLDA1 | pleckstrin homology-like domain, family A, member 1 | 0.0423544 |
| FLNB | filamin B, beta | 0.0416325 |
| PCDHB16 | protocadherin beta 16 | 0.0411705 |
| ITPR2 | inositol 1,4,5-trisphosphate receptor, type 2 | 0.0410052 |
| SHB | Src homology 2 domain containing adaptor protein B | 0.0407737 |
| BCL2L1 | BCL2-like 1 | 0.0402052 |
| NF1 | neurofibromin 1 | 0.039905 |
| PKP2 | plakophilin 2 | 0.0396522 |
| EPCAM | epithelial cell adhesion molecule | 0.0395191 |
| RHPN2 | rhophilin, Rho GTPase binding protein 2 | 0.039457 |
| DSG2 | desmoglein 2 | 0.0391829 |
| MYH9 | myosin, heavy chain 9, non-muscle | 0.0390891 |
| SHROOM3 | shroom family member 3 | 0.0390281 |
| LOC112694756 | uncharaterized LOC112694756 | 0.0388306 |
| KCNK1 | potassium channel, two pore domain subfamily K, member 1 | 0.0387641 |
| PIGR | polymeric immunoglobulin receptor | 0.0386536 |
| ANXA11 | annexin A11 | 0.0385293 |
| CD9 | CD9 molecule | 0.0383106 |
| CAB39 | calcium binding protein 39 | 0.0382472 |
| FOXP1 | forkhead box P1 | 0.0382148 |
| TXNIP | thioredoxin interacting protein | 0.0379304 |
| MYO1E | myosin IE | 0.0376576 |
| VDR | vitamin D (1,25- dihydroxyvitamin D3) receptor | 0.037407 |
| ASPH | aspartate beta-hydroxylase | 0.0369806 |
| FERMT1 | fermitin family member 1 | 0.0369714 |
| GPA33 | glycoprotein A33 (transmembrane) | 0.036803 |
| ITGB4 | integrin, beta 4 | 0.0366833 |
| SOX9 | SRY (sex determining region Y)-box 9 | 0.0365294 |
| DGKD | diacylglycerol kinase, delta 130kDa | 0.0361931 |
| P4HA1 | prolyl 4-hydroxylase, alpha polypeptide I | 0.0358882 |
| FOXO1 | forkhead box O1 | 0.0358353 |
| RPL3 | ribosomal protein L3 | 0.0357444 |
| MICAL2 | microtubule associated monooxygenase, calponin and LIM domain containing 2 | 0.0357412 |
| LOC102724023 | ES1 protein homolog, mitochondrial | 0.0356863 |
| LRRFIP1 | leucine rich repeat (in FLII) interacting protein 1 | 0.0351734 |
| Symbol | Name | Standardized Value |
|---|---|---|
| HSPA5 | heat shock 70kDa protein 5 (glucose-regulated protein, 78kDa) | -0.167499 |
| HSP90B1 | heat shock protein 90kDa beta (Grp94), member 1 | -0.122013 |
| TPT1 | tumor protein, translationally-controlled 1 | -0.0572946 |
| ZSWIM6 | zinc finger, SWIM-type containing 6 | -0.0448006 |
| TMSB10 | thymosin beta 10 | -0.0436214 |
| HERPUD1 | homocysteine-inducible, endoplasmic reticulum stress-inducible, ubiquitin-like domain member 1 | -0.0376492 |
| VCL | vinculin | -0.0374994 |
| RPS19 | ribosomal protein S19 | -0.0369749 |
| CALR | calreticulin | -0.0343147 |
| HSP90AA1 | heat shock protein 90kDa alpha (cytosolic), class A member 1 | -0.0341723 |
| RPL36 | ribosomal protein L36 | -0.0337841 |
| SLCO1B3-SLCO1B7 | SLCO1B3-SLCO1B7 readthrough | -0.0327582 |
| RPS8 | ribosomal protein S8 | -0.0311681 |
| SLC35F3 | solute carrier family 35, member F3 | -0.0310704 |
| GBE1 | glucan (1,4-alpha-), branching enzyme 1 | -0.0289801 |
| DNAJC3 | DnaJ (Hsp40) homolog, subfamily C, member 3 | -0.0280289 |
| RPL35A | ribosomal protein L35a | -0.0275366 |
| FHIT | fragile histidine triad | -0.0264596 |
| EGFR | epidermal growth factor receptor | -0.0264513 |
| INTS6 | integrator complex subunit 6 | -0.0262317 |
| RPL37A | ribosomal protein L37a | -0.0247974 |
| RPL34 | ribosomal protein L34 | -0.0247924 |
| S100P | S100 calcium binding protein P | -0.0242633 |
| AGR2 | anterior gradient 2 | -0.0239463 |
| EXT1 | exostosin glycosyltransferase 1 | -0.0239218 |
| RPS23 | ribosomal protein S23 | -0.0238284 |
| GFPT1 | glutamine--fructose-6-phosphate transaminase 1 | -0.0234696 |
| RPL9 | ribosomal protein L9 | -0.0228207 |
| RPL23 | ribosomal protein L23 | -0.0226024 |
| NPSR1 | neuropeptide S receptor 1 | -0.0215877 |
| RPS29 | ribosomal protein S29 | -0.0211052 |
| PCDH9 | protocadherin 9 | -0.0206769 |
| ANXA1 | annexin A1 | -0.0198585 |
| DDIT3 | DNA-damage-inducible transcript 3 | -0.0198568 |
| MORF4L2 | mortality factor 4 like 2 | -0.0191911 |
| PDIA4 | protein disulfide isomerase family A, member 4 | -0.0191359 |
| RPL28 | ribosomal protein L28 | -0.0187816 |
| FBXO11 | F-box protein 11 | -0.0186718 |
| PHLDB2 | pleckstrin homology-like domain, family B, member 2 | -0.0183988 |
| RPS24 | ribosomal protein S24 | -0.01827 |
| RPLP2 | ribosomal protein, large, P2 | -0.0181616 |
| PTPRK | protein tyrosine phosphatase, receptor type, K | -0.018076 |
| SQSTM1 | sequestosome 1 | -0.017981 |
| RPL18 | ribosomal protein L18 | -0.0177341 |
| ATP2A2 | ATPase, Ca++ transporting, cardiac muscle, slow twitch 2 | -0.0174823 |
| HNRNPA2B1 | heterogeneous nuclear ribonucleoprotein A2/B1 | -0.0174277 |
| CATSPERB | catsper channel auxiliary subunit beta | -0.0173883 |
| BCAT1 | branched chain amino-acid transaminase 1, cytosolic | -0.0173116 |
| SETX | senataxin | -0.0172225 |
| RPS6 | ribosomal protein S6 | -0.017064 |
| GRB10 | growth factor receptor-bound protein 10 | -0.0168766 |
| TAS2R14 | taste receptor, type 2, member 14 | -0.0168501 |
| RPS27A | ribosomal protein S27a | -0.0168498 |
| ERRFI1 | ERBB receptor feedback inhibitor 1 | -0.0166288 |
| RPLP1 | ribosomal protein, large, P1 | -0.0165768 |
| SGMS2 | sphingomyelin synthase 2 | -0.0164035 |
| IARS1 | isoleucyl-tRNA synthetase 1 | -0.0163328 |
| RPS6KA5 | ribosomal protein S6 kinase, 90kDa, polypeptide 5 | -0.0161331 |
| MBNL1 | muscleblind-like splicing regulator 1 | -0.0159254 |
| RNF217 | ring finger protein 217 | -0.0157684 |
| IFRD1 | interferon-related developmental regulator 1 | -0.0157609 |
| VCAN | versican | -0.0157605 |
| FOSB | FBJ murine osteosarcoma viral oncogene homolog B | -0.0157563 |
| USP53 | ubiquitin specific peptidase 53 | -0.0156614 |
| KLF5 | Kruppel-like factor 5 (intestinal) | -0.0153884 |
| RAP1B | RAP1B, member of RAS oncogene family | -0.0153479 |
| RTN3 | reticulon 3 | -0.015301 |
| RPL38 | ribosomal protein L38 | -0.0150272 |
| NABP1 | nucleic acid binding protein 1 | -0.0150233 |
| LARP1B | La ribonucleoprotein domain family, member 1B | -0.0150197 |
| SLC5A3 | solute carrier family 5 (sodium/myo-inositol cotransporter), member 3 | -0.0149405 |
| DCBLD2 | discoidin, CUB and LCCL domain containing 2 | -0.0147183 |
| PRR5L | proline rich 5 like | -0.0147016 |
| RPS25 | ribosomal protein S25 | -0.0145895 |
| RPS12 | ribosomal protein S12 | -0.0145036 |
| UBAP2 | ubiquitin associated protein 2 | -0.0142119 |
| EZH2 | enhancer of zeste 2 polycomb repressive complex 2 subunit | -0.0140719 |
| RPS21 | ribosomal protein S21 | -0.013889 |
| RAD51B | RAD51 paralog B | -0.0138681 |
| FUS | FUS RNA binding protein | -0.0138105 |
| RND3 | Rho family GTPase 3 | -0.0135995 |
| RPL26 | ribosomal protein L26 | -0.0135132 |
| RPS20 | ribosomal protein S20 | -0.0133927 |
| WWOX | WW domain containing oxidoreductase | -0.013376 |
| BZW2 | basic leucine zipper and W2 domains 2 | -0.0128397 |
| ISG15 | ISG15 ubiquitin-like modifier | -0.0127523 |
| RPS26 | ribosomal protein S26 | -0.0126898 |
| MARCHF3 | membrane associated ring-CH-type finger 3 | -0.0126648 |
| RPS3 | ribosomal protein S3 | -0.0125461 |
| PDE4D | phosphodiesterase 4D, cAMP-specific | -0.0125077 |
| FMNL2 | formin-like 2 | -0.0124812 |
| PTPRB | protein tyrosine phosphatase, receptor type, B | -0.0124468 |
| KHDRBS3 | KH domain containing, RNA binding, signal transduction associated 3 | -0.0122088 |
| SEL1L | sel-1 suppressor of lin-12-like (C. elegans) | -0.0122061 |
| DNAJA1 | DnaJ (Hsp40) homolog, subfamily A, member 1 | -0.01209 |
| POF1B | premature ovarian failure, 1B | -0.0119813 |
| RPS13 | ribosomal protein S13 | -0.0119309 |
| HSPH1 | heat shock 105kDa/110kDa protein 1 | -0.0118733 |
| DENND1A | DENN/MADD domain containing 1A | -0.0118054 |
| RPL31 | ribosomal protein L31 | -0.0116863 |
