| Dataset | Tahoe Therapeutics Tahoe 100M Perturbation Atlas |
| Category | transcriptomics |
| Type | cell type |
| Description | Esmolol (hydrochloride) perturbation in LoVo cell line (Tahoe Therapeutics) |
| Similar Terms | |
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200 genes differentially expressed following the Esmolol (hydrochloride)_LoVo drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| EPS8 | epidermal growth factor receptor pathway substrate 8 | 0.185133 |
| THSD4 | thrombospondin, type I, domain containing 4 | 0.171465 |
| FAT1 | FAT atypical cadherin 1 | 0.150096 |
| FLNB | filamin B, beta | 0.143615 |
| PABPC1 | poly(A) binding protein, cytoplasmic 1 | 0.106916 |
| SLCO1B3 | solute carrier organic anion transporter family, member 1B3 | 0.105349 |
| MYOF | myoferlin | 0.100102 |
| MSI2 | musashi RNA-binding protein 2 | 0.0867493 |
| PTPRG | protein tyrosine phosphatase, receptor type, G | 0.0841666 |
| PTPRK | protein tyrosine phosphatase, receptor type, K | 0.0830981 |
| CALB1 | calbindin 1, 28kDa | 0.0821792 |
| ITGA6 | integrin, alpha 6 | 0.081494 |
| TRIM2 | tripartite motif containing 2 | 0.0798251 |
| HSP90B1 | heat shock protein 90kDa beta (Grp94), member 1 | 0.070522 |
| ANXA2 | annexin A2 | 0.0694748 |
| SLC7A11 | solute carrier family 7 (anionic amino acid transporter light chain, xc- system), member 11 | 0.0679206 |
| EZR | ezrin | 0.0672291 |
| AKAP13 | A kinase (PRKA) anchor protein 13 | 0.0657195 |
| MDM2 | MDM2 proto-oncogene, E3 ubiquitin protein ligase | 0.0641837 |
| ARIH1 | ariadne RBR E3 ubiquitin protein ligase 1 | 0.0614133 |
| GAPDH | glyceraldehyde-3-phosphate dehydrogenase | 0.060804 |
| EEF2 | eukaryotic translation elongation factor 2 | 0.0601606 |
| FOXP1 | forkhead box P1 | 0.0574454 |
| ARHGAP26 | Rho GTPase activating protein 26 | 0.0572844 |
| P3H2 | prolyl 3-hydroxylase 2 | 0.057228 |
| PPP3CA | protein phosphatase 3, catalytic subunit, alpha isozyme | 0.056296 |
| TBC1D8 | TBC1 domain family, member 8 (with GRAM domain) | 0.0557566 |
| SHROOM3 | shroom family member 3 | 0.0555802 |
| RAD51B | RAD51 paralog B | 0.054961 |
| ACTG1 | actin gamma 1 | 0.0539632 |
| TBL1XR1 | transducin (beta)-like 1 X-linked receptor 1 | 0.0531861 |
| RIMKLB | ribosomal modification protein rimK-like family member B | 0.0527274 |
| TNRC18 | trinucleotide repeat containing 18 | 0.0519228 |
| GOLGA4 | golgin A4 | 0.0509562 |
| KMT2C | lysine (K)-specific methyltransferase 2C | 0.0491345 |
| MPRIP | myosin phosphatase Rho interacting protein | 0.0481355 |
| CDC42BPA | CDC42 binding protein kinase alpha (DMPK-like) | 0.0480504 |
| CUX1 | cut-like homeobox 1 | 0.0477057 |
| RPS2 | ribosomal protein S2 | 0.0475884 |
| UBE2H | ubiquitin-conjugating enzyme E2H | 0.0464459 |
| LMO7 | LIM domain 7 | 0.0460747 |
| ETNK1 | ethanolamine kinase 1 | 0.0459471 |
| CEMIP | cell migration inducing protein, hyaluronan binding | 0.0459003 |
| SRRM2 | serine/arginine repetitive matrix 2 | 0.0450908 |
| CTBP2 | C-terminal binding protein 2 | 0.0450341 |
| ANKRD11 | ankyrin repeat domain 11 | 0.0442559 |
| PKP2 | plakophilin 2 | 0.0433634 |
| DSPP | dentin sialophosphoprotein | 0.0427231 |
| CYSTM1 | cysteine-rich transmembrane module containing 1 | 0.0418331 |
| MAML2 | mastermind-like 2 (Drosophila) | 0.0417917 |
| TAF1D | TATA box binding protein (TBP)-associated factor, RNA polymerase I, D, 41kDa | 0.0417702 |
| MYO1E | myosin IE | 0.0412131 |
| B4GALNT3 | beta-1,4-N-acetyl-galactosaminyl transferase 3 | 0.0409609 |
| ANKRD17 | ankyrin repeat domain 17 | 0.0407736 |
| KIF5B | kinesin family member 5B | 0.040511 |
| RAP1B | RAP1B, member of RAS oncogene family | 0.0405072 |
| DSCAM | Down syndrome cell adhesion molecule | 0.0403358 |
| HNRNPA1 | heterogeneous nuclear ribonucleoprotein A1 | 0.0394948 |
| TLN2 | talin 2 | 0.0393039 |
| VCL | vinculin | 0.0392287 |
| PLAC8 | placenta-specific 8 | 0.0388889 |
| POTEF | POTE ankyrin domain family, member F | 0.0387957 |
| RPL3 | ribosomal protein L3 | 0.0386352 |
| PCDHB16 | protocadherin beta 16 | 0.0383759 |
| MED13L | mediator complex subunit 13-like | 0.0382554 |
| RPL13A | ribosomal protein L13a | 0.0378833 |
| TCF12 | transcription factor 12 | 0.0377648 |
| FOXO1 | forkhead box O1 | 0.0377422 |
| NPM1 | nucleophosmin (nucleolar phosphoprotein B23, numatrin) | 0.0373288 |
| RPS6 | ribosomal protein S6 | 0.0371101 |
| HSP90AB1 | heat shock protein 90kDa alpha (cytosolic), class B member 1 | 0.0370369 |
| GARS1 | glycyl-tRNA synthetase 1 | 0.037026 |
| DOCK5 | dedicator of cytokinesis 5 | 0.0368474 |
| AGAP1 | ArfGAP with GTPase domain, ankyrin repeat and PH domain 1 | 0.0365874 |
| FGD4 | FYVE, RhoGEF and PH domain containing 4 | 0.0364967 |
| NOS1AP | nitric oxide synthase 1 (neuronal) adaptor protein | 0.0364965 |
| MYO1D | myosin ID | 0.0364232 |
| HSPD1 | heat shock 60kDa protein 1 (chaperonin) | 0.0362945 |
| IARS1 | isoleucyl-tRNA synthetase 1 | 0.0361774 |
| RNF213 | ring finger protein 213 | 0.0360435 |
| IGF2BP2 | insulin-like growth factor 2 mRNA binding protein 2 | 0.0354693 |
| LPP | LIM domain containing preferred translocation partner in lipoma | 0.0352542 |
| PPFIBP1 | PTPRF interacting protein, binding protein 1 (liprin beta 1) | 0.0351417 |
| MBNL1 | muscleblind-like splicing regulator 1 | 0.035053 |
| ZCCHC7 | zinc finger, CCHC domain containing 7 | 0.0348321 |
| SQSTM1 | sequestosome 1 | 0.0347381 |
| OXSR1 | oxidative stress responsive 1 | 0.0346886 |
| SLTM | SAFB-like, transcription modulator | 0.034383 |
| SETD5 | SET domain containing 5 | 0.034343 |
| ESYT2 | extended synaptotagmin-like protein 2 | 0.0339616 |
| LAMA4 | laminin, alpha 4 | 0.0338691 |
| ACTN4 | actinin, alpha 4 | 0.0336291 |
| SPTBN1 | spectrin, beta, non-erythrocytic 1 | 0.0335395 |
| AHCYL2 | adenosylhomocysteinase-like 2 | 0.0334575 |
| PSME4 | proteasome (prosome, macropain) activator subunit 4 | 0.0333669 |
| ZC3HAV1 | zinc finger CCCH-type, antiviral 1 | 0.0331991 |
| EIF3A | eukaryotic translation initiation factor 3, subunit A | 0.0331763 |
| GMDS | GDP-mannose 4,6-dehydratase | 0.0330535 |
| CTNNA1 | catenin (cadherin-associated protein), alpha 1, 102kDa | 0.033017 |
| GFPT1 | glutamine--fructose-6-phosphate transaminase 1 | 0.0329265 |
| Symbol | Name | Standardized Value |
|---|---|---|
| RPLP1 | ribosomal protein, large, P1 | -0.0856173 |
| TMSB10 | thymosin beta 10 | -0.0682447 |
| TPT1 | tumor protein, translationally-controlled 1 | -0.0616723 |
| RPL35A | ribosomal protein L35a | -0.0488868 |
| RPL31 | ribosomal protein L31 | -0.0459537 |
| IL1RAPL1 | interleukin 1 receptor accessory protein-like 1 | -0.0453752 |
| RPS19 | ribosomal protein S19 | -0.0417587 |
| RPS23 | ribosomal protein S23 | -0.0338863 |
| RPL34 | ribosomal protein L34 | -0.0319773 |
| RPS24 | ribosomal protein S24 | -0.0286271 |
| RPL32 | ribosomal protein L32 | -0.0263873 |
| RPS5 | ribosomal protein S5 | -0.0251989 |
| HLA-B | major histocompatibility complex, class I, B | -0.0239568 |
| RPLP2 | ribosomal protein, large, P2 | -0.0237103 |
| FRMD5 | FERM domain containing 5 | -0.0223321 |
| ITGA2 | integrin, alpha 2 (CD49B, alpha 2 subunit of VLA-2 receptor) | -0.0222768 |
| RPL38 | ribosomal protein L38 | -0.0217426 |
| F3 | coagulation factor III (thromboplastin, tissue factor) | -0.0200973 |
| ERO1A | endoplasmic reticulum oxidoreductase 1 alpha | -0.0199631 |
| FTL | ferritin, light polypeptide | -0.0169389 |
| SERPINB1 | serpin peptidase inhibitor, clade B (ovalbumin), member 1 | -0.0169248 |
| CEACAM5 | carcinoembryonic antigen-related cell adhesion molecule 5 | -0.0165103 |
| DNAJA1 | DnaJ (Hsp40) homolog, subfamily A, member 1 | -0.0161763 |
| RPS17 | ribosomal protein S17 | -0.0160555 |
| HPGD | hydroxyprostaglandin dehydrogenase 15-(NAD) | -0.0158533 |
| HSP90AA1 | heat shock protein 90kDa alpha (cytosolic), class A member 1 | -0.0156707 |
| RPL9 | ribosomal protein L9 | -0.0150039 |
| PHLDA1 | pleckstrin homology-like domain, family A, member 1 | -0.0143408 |
| IER3 | immediate early response 3 | -0.0139292 |
| TPM4 | tropomyosin 4 | -0.0131303 |
| CALM1 | calmodulin 1 (phosphorylase kinase, delta) | -0.0129336 |
| NPSR1 | neuropeptide S receptor 1 | -0.0126694 |
| RPL36A | ribosomal protein L36a | -0.0126251 |
| UBA52 | ubiquitin A-52 residue ribosomal protein fusion product 1 | -0.0124115 |
| RPL4 | ribosomal protein L4 | -0.0124049 |
| UQCRQ | ubiquinol-cytochrome c reductase, complex III subunit VII, 9.5kDa | -0.0123443 |
| RPS15 | ribosomal protein S15 | -0.0121367 |
| IFI6 | interferon, alpha-inducible protein 6 | -0.0119039 |
| RPS13 | ribosomal protein S13 | -0.0116973 |
| RPS21 | ribosomal protein S21 | -0.0114593 |
| CCT4 | chaperonin containing TCP1, subunit 4 (delta) | -0.0114273 |
| INHBA | inhibin, beta A | -0.0113738 |
| RPS11 | ribosomal protein S11 | -0.0107183 |
| PTPRR | protein tyrosine phosphatase, receptor type, R | -0.0103016 |
| RPL37A | ribosomal protein L37a | -0.0102692 |
| ISG15 | ISG15 ubiquitin-like modifier | -0.0102042 |
| RPS29 | ribosomal protein S29 | -0.0101038 |
| TSPAN8 | tetraspanin 8 | -0.00993353 |
| PNRC1 | proline-rich nuclear receptor coactivator 1 | -0.00977115 |
| CCNH | cyclin H | -0.00973604 |
| RPL36AL | ribosomal protein L36a-like | -0.00972081 |
| INTS6 | integrator complex subunit 6 | -0.00970543 |
| RPL35 | ribosomal protein L35 | -0.00943807 |
| RPS6KA5 | ribosomal protein S6 kinase, 90kDa, polypeptide 5 | -0.00922728 |
| APOL1 | apolipoprotein L, 1 | -0.00876316 |
| S100P | S100 calcium binding protein P | -0.00874849 |
| S100A11 | S100 calcium binding protein A11 | -0.00859934 |
| DSG2 | desmoglein 2 | -0.00857462 |
| DSC3 | desmocollin 3 | -0.00854954 |
| DCBLD2 | discoidin, CUB and LCCL domain containing 2 | -0.0084918 |
| RPL39 | ribosomal protein L39 | -0.00837056 |
| EEF1D | eukaryotic translation elongation factor 1 delta (guanine nucleotide exchange protein) | -0.00819154 |
| CEACAM6 | carcinoembryonic antigen-related cell adhesion molecule 6 (non-specific cross reacting antigen) | -0.00810326 |
| NDRG1 | N-myc downstream regulated 1 | -0.00800019 |
| RPS27 | ribosomal protein S27 | -0.00793968 |
| GLCCI1 | glucocorticoid induced 1 | -0.00793515 |
| BMP4 | bone morphogenetic protein 4 | -0.00790296 |
| ABHD3 | abhydrolase domain containing 3 | -0.00777282 |
| CD63 | CD63 molecule | -0.00774215 |
| NDUFA4 | NDUFA4, mitochondrial complex associated | -0.00771751 |
| LRRC23 | leucine rich repeat containing 23 | -0.00770659 |
| RPS8 | ribosomal protein S8 | -0.00768241 |
| RPS10 | ribosomal protein S10 | -0.0075905 |
| RPS25 | ribosomal protein S25 | -0.00758377 |
| SAMD9 | sterile alpha motif domain containing 9 | -0.00756952 |
| COX5A | cytochrome c oxidase subunit Va | -0.00756759 |
| IGFBP3 | insulin-like growth factor binding protein 3 | -0.00754269 |
| HSPH1 | heat shock 105kDa/110kDa protein 1 | -0.00750715 |
| RPS4X | ribosomal protein S4, X-linked | -0.00741825 |
| NPR2 | natriuretic peptide receptor 2 | -0.00736313 |
| RPL19 | ribosomal protein L19 | -0.00723445 |
| MYL6 | myosin, light chain 6, alkali, smooth muscle and non-muscle | -0.00719101 |
| AGR2 | anterior gradient 2 | -0.00718547 |
| SLC5A3 | solute carrier family 5 (sodium/myo-inositol cotransporter), member 3 | -0.0071354 |
| ARL4C | ADP-ribosylation factor-like 4C | -0.00708588 |
| MYDGF | myeloid-derived growth factor | -0.00688132 |
| BMAL2 | basic helix-loop-helix ARNT like 2 | -0.00686747 |
| NR2F2 | nuclear receptor subfamily 2, group F, member 2 | -0.00685817 |
| PLIN3 | perilipin 3 | -0.00685049 |
| SELENOK | selenoprotein K | -0.00681038 |
| NUDT4 | nudix (nucleoside diphosphate linked moiety X)-type motif 4 | -0.0068031 |
| SH3BGRL3 | SH3 domain binding glutamate-rich protein like 3 | -0.00680048 |
| RPL5 | ribosomal protein L5 | -0.00668319 |
| RPL7 | ribosomal protein L7 | -0.00653202 |
| NFKBIZ | nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor, zeta | -0.0065271 |
| RPL23 | ribosomal protein L23 | -0.00650639 |
| RESF1 | retroelement silencing factor 1 | -0.00648913 |
| UQCRH | ubiquinol-cytochrome c reductase hinge protein | -0.0064724 |
| DDX1 | DEAD (Asp-Glu-Ala-Asp) box helicase 1 | -0.00646636 |
| DKK1 | dickkopf WNT signaling pathway inhibitor 1 | -0.00635895 |
