| Dataset | Tahoe Therapeutics Tahoe 100M Perturbation Atlas |
| Category | transcriptomics |
| Type | cell type |
| Description | Esmolol (hydrochloride) perturbation in NCI-H661 cell line (Tahoe Therapeutics) |
| Similar Terms | |
| Downloads & Tools |
200 genes differentially expressed following the Esmolol (hydrochloride)_NCI-H661 drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| COL5A2 | collagen, type V, alpha 2 | 0.157375 |
| PCLO | piccolo presynaptic cytomatrix protein | 0.0886322 |
| MKI67 | marker of proliferation Ki-67 | 0.077801 |
| ZNF292 | zinc finger protein 292 | 0.0758244 |
| TENM3 | teneurin transmembrane protein 3 | 0.0739738 |
| UACA | uveal autoantigen with coiled-coil domains and ankyrin repeats | 0.0726609 |
| PEG10 | paternally expressed 10 | 0.0593315 |
| METAP2 | methionyl aminopeptidase 2 | 0.0551904 |
| PDGFC | platelet derived growth factor C | 0.0533521 |
| HSP90AB1 | heat shock protein 90kDa alpha (cytosolic), class B member 1 | 0.0521356 |
| DST | dystonin | 0.0447036 |
| PABPC1 | poly(A) binding protein, cytoplasmic 1 | 0.0443341 |
| CABLES1 | Cdk5 and Abl enzyme substrate 1 | 0.0440212 |
| CENPF | centromere protein F, 350/400kDa | 0.0435867 |
| ZNF608 | zinc finger protein 608 | 0.0430477 |
| CENPE | centromere protein E, 312kDa | 0.040919 |
| ZFAND3 | zinc finger, AN1-type domain 3 | 0.0405767 |
| CDH10 | cadherin 10, type 2 (T2-cadherin) | 0.0395551 |
| DOCK5 | dedicator of cytokinesis 5 | 0.0394958 |
| H1-0 | H1.0 linker histone | 0.039078 |
| ARHGAP15 | Rho GTPase activating protein 15 | 0.0380035 |
| G2E3 | G2/M-phase specific E3 ubiquitin protein ligase | 0.0364257 |
| SHROOM3 | shroom family member 3 | 0.0359489 |
| SORBS2 | sorbin and SH3 domain containing 2 | 0.035812 |
| CDH6 | cadherin 6, type 2, K-cadherin (fetal kidney) | 0.0357883 |
| GPC3 | glypican 3 | 0.0355328 |
| UTRN | utrophin | 0.0350365 |
| SYT1 | synaptotagmin I | 0.0343146 |
| AKAP9 | A kinase (PRKA) anchor protein 9 | 0.034227 |
| ADGRV1 | adhesion G protein-coupled receptor V1 | 0.0337535 |
| PRR16 | proline rich 16 | 0.0335634 |
| SEMA3C | sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3C | 0.0314011 |
| TOP2A | topoisomerase (DNA) II alpha 170kDa | 0.0306571 |
| ANKRD33B | ankyrin repeat domain 33B | 0.0300539 |
| CKAP2 | cytoskeleton associated protein 2 | 0.0293864 |
| RALGAPA1 | Ral GTPase activating protein, alpha subunit 1 (catalytic) | 0.0293784 |
| PRKDC | protein kinase, DNA-activated, catalytic polypeptide | 0.0289019 |
| DDAH1 | dimethylarginine dimethylaminohydrolase 1 | 0.0286659 |
| ANKRD12 | ankyrin repeat domain 12 | 0.0277421 |
| SOX5 | SRY (sex determining region Y)-box 5 | 0.0276961 |
| PRRC2A | proline-rich coiled-coil 2A | 0.0276244 |
| SMC4 | structural maintenance of chromosomes 4 | 0.0262438 |
| ATP5F1B | ATP synthase F1 subunit beta | 0.0252927 |
| PPP3CA | protein phosphatase 3, catalytic subunit, alpha isozyme | 0.0252685 |
| FIGN | fidgetin | 0.0252363 |
| SGO2 | shugoshin 2 | 0.025207 |
| TRPS1 | trichorhinophalangeal syndrome I | 0.0246979 |
| SET | SET nuclear proto-oncogene | 0.0240179 |
| CDH19 | cadherin 19, type 2 | 0.0239311 |
| VAPA | VAMP (vesicle-associated membrane protein)-associated protein A, 33kDa | 0.0237263 |
| HCN1 | hyperpolarization activated cyclic nucleotide gated potassium channel 1 | 0.0236548 |
| USP3 | ubiquitin specific peptidase 3 | 0.0236348 |
| SUPT5H | suppressor of Ty 5 homolog (S. cerevisiae) | 0.0234956 |
| PGPEP1L | pyroglutamyl-peptidase I-like | 0.0233744 |
| PPFIBP1 | PTPRF interacting protein, binding protein 1 (liprin beta 1) | 0.0233499 |
| DLGAP5 | discs, large (Drosophila) homolog-associated protein 5 | 0.0232895 |
| RAD21 | RAD21 homolog (S. pombe) | 0.0231632 |
| SP3 | Sp3 transcription factor | 0.0231598 |
| ZC3H12B | zinc finger CCCH-type containing 12B | 0.0230887 |
| NCKAP1 | NCK-associated protein 1 | 0.0229488 |
| POLR2B | polymerase (RNA) II (DNA directed) polypeptide B, 140kDa | 0.0225324 |
| DPYD | dihydropyrimidine dehydrogenase | 0.0218779 |
| BLTP1 | bridge-like lipid transfer protein family member 1 | 0.0218079 |
| IQGAP1 | IQ motif containing GTPase activating protein 1 | 0.0217298 |
| KIF1B | kinesin family member 1B | 0.0215555 |
| MIER1 | mesoderm induction early response 1, transcriptional regulator | 0.0214171 |
| SRRM2 | serine/arginine repetitive matrix 2 | 0.0211459 |
| PLEKHG1 | pleckstrin homology domain containing, family G (with RhoGef domain) member 1 | 0.0209441 |
| FLNA | filamin A, alpha | 0.0208202 |
| RPL3 | ribosomal protein L3 | 0.0201676 |
| CCNA2 | cyclin A2 | 0.0201521 |
| CKAP5 | cytoskeleton associated protein 5 | 0.0201355 |
| MKLN1 | muskelin 1, intracellular mediator containing kelch motifs | 0.0200265 |
| PRPF8 | pre-mRNA processing factor 8 | 0.0198973 |
| RAD23B | RAD23 homolog B (S. cerevisiae) | 0.0197891 |
| DYNC2H1 | dynein, cytoplasmic 2, heavy chain 1 | 0.019747 |
| SMARCA1 | SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily a, member 1 | 0.0197346 |
| MPG | N-methylpurine-DNA glycosylase | 0.0197236 |
| LRMDA | leucine rich melanocyte differentiation associated | 0.019709 |
| RNF13 | ring finger protein 13 | 0.0196811 |
| KIF5B | kinesin family member 5B | 0.0196384 |
| HP1BP3 | heterochromatin protein 1, binding protein 3 | 0.0195622 |
| RUNX1T1 | runt-related transcription factor 1; translocated to, 1 (cyclin D-related) | 0.0195551 |
| CSDE1 | cold shock domain containing E1, RNA-binding | 0.0195214 |
| PROS1 | protein S (alpha) | 0.0195 |
| TAB2 | TGF-beta activated kinase 1/MAP3K7 binding protein 2 | 0.0194533 |
| KIF4A | kinesin family member 4A | 0.0193305 |
| CRISPLD1 | cysteine-rich secretory protein LCCL domain containing 1 | 0.0193272 |
| FOXP2 | forkhead box P2 | 0.0193265 |
| CDC50A | cell division cycle 50 P4-ATPase accessory subunit A | 0.019319 |
| MIS18BP1 | MIS18 binding protein 1 | 0.0192167 |
| PCDH18 | protocadherin 18 | 0.0189993 |
| AURKA | aurora kinase A | 0.0189825 |
| KLF7 | Kruppel-like factor 7 (ubiquitous) | 0.0189236 |
| TCEA1 | transcription elongation factor A (SII), 1 | 0.0187623 |
| PNISR | PNN-interacting serine/arginine-rich protein | 0.0185938 |
| DAG1 | dystroglycan 1 (dystrophin-associated glycoprotein 1) | 0.018564 |
| ALDH1A1 | aldehyde dehydrogenase 1 family, member A1 | 0.0185398 |
| PAPOLA | poly(A) polymerase alpha | 0.018449 |
| CPSF6 | cleavage and polyadenylation specific factor 6, 68kDa | 0.0182983 |
| Symbol | Name | Standardized Value |
|---|---|---|
| HSPA5 | heat shock 70kDa protein 5 (glucose-regulated protein, 78kDa) | -0.105696 |
| TMSB10 | thymosin beta 10 | -0.0807544 |
| PTMA | prothymosin, alpha | -0.0641255 |
| RPS6 | ribosomal protein S6 | -0.0484587 |
| IMMP2L | IMP2 inner mitochondrial membrane peptidase-like (S. cerevisiae) | -0.0458949 |
| COL3A1 | collagen, type III, alpha 1 | -0.0437608 |
| TPT1 | tumor protein, translationally-controlled 1 | -0.0431084 |
| RPS8 | ribosomal protein S8 | -0.0427929 |
| RPL23 | ribosomal protein L23 | -0.0408226 |
| RPS16 | ribosomal protein S16 | -0.0398257 |
| WSB1 | WD repeat and SOCS box containing 1 | -0.0390278 |
| RPL35A | ribosomal protein L35a | -0.0389258 |
| ZC3HAV1 | zinc finger CCCH-type, antiviral 1 | -0.0386426 |
| MDK | midkine (neurite growth-promoting factor 2) | -0.0383455 |
| COL1A2 | collagen, type I, alpha 2 | -0.0379822 |
| MARCKS | myristoylated alanine-rich protein kinase C substrate | -0.0370607 |
| COL11A1 | collagen, type XI, alpha 1 | -0.0362003 |
| HDAC9 | histone deacetylase 9 | -0.0353809 |
| GAPDH | glyceraldehyde-3-phosphate dehydrogenase | -0.0351592 |
| IRF2BP2 | interferon regulatory factor 2 binding protein 2 | -0.0346614 |
| PCDH9 | protocadherin 9 | -0.0322255 |
| RPS13 | ribosomal protein S13 | -0.0321347 |
| RPL37A | ribosomal protein L37a | -0.0318752 |
| UPP1 | uridine phosphorylase 1 | -0.0313925 |
| RPS21 | ribosomal protein S21 | -0.0313069 |
| RAB1A | RAB1A, member RAS oncogene family | -0.0312901 |
| ADGRL2 | adhesion G protein-coupled receptor L2 | -0.0302078 |
| SFRP4 | secreted frizzled-related protein 4 | -0.0300142 |
| DYRK1A | dual-specificity tyrosine-(Y)-phosphorylation regulated kinase 1A | -0.0297249 |
| CADM2 | cell adhesion molecule 2 | -0.0296749 |
| P4HA1 | prolyl 4-hydroxylase, alpha polypeptide I | -0.0295882 |
| TTC28 | tetratricopeptide repeat domain 28 | -0.0291582 |
| ISG15 | ISG15 ubiquitin-like modifier | -0.0291223 |
| HSPD1 | heat shock 60kDa protein 1 (chaperonin) | -0.0287424 |
| KDM3A | lysine (K)-specific demethylase 3A | -0.0281031 |
| CALR | calreticulin | -0.0278001 |
| RPLP2 | ribosomal protein, large, P2 | -0.0274931 |
| NRG1 | neuregulin 1 | -0.0271012 |
| SMG1 | SMG1 phosphatidylinositol 3-kinase-related kinase | -0.0267948 |
| RPS19 | ribosomal protein S19 | -0.026622 |
| SREBF2 | sterol regulatory element binding transcription factor 2 | -0.0265233 |
| NHSL1 | NHS-like 1 | -0.0264005 |
| SOX2 | SRY (sex determining region Y)-box 2 | -0.0263493 |
| CTNNA3 | catenin (cadherin-associated protein), alpha 3 | -0.0262475 |
| FUS | FUS RNA binding protein | -0.0253907 |
| ERO1A | endoplasmic reticulum oxidoreductase 1 alpha | -0.0250203 |
| HSP90B1 | heat shock protein 90kDa beta (Grp94), member 1 | -0.0247141 |
| RPL34 | ribosomal protein L34 | -0.0245235 |
| SRPK2 | SRSF protein kinase 2 | -0.024465 |
| STAG2 | stromal antigen 2 | -0.0244315 |
| CHD1 | chromodomain helicase DNA binding protein 1 | -0.0243631 |
| FNDC3B | fibronectin type III domain containing 3B | -0.0242109 |
| BMPR2 | bone morphogenetic protein receptor, type II (serine/threonine kinase) | -0.0238002 |
| SPAG9 | sperm associated antigen 9 | -0.0233672 |
| VIM | vimentin | -0.0233002 |
| RPL31 | ribosomal protein L31 | -0.0231744 |
| ESYT2 | extended synaptotagmin-like protein 2 | -0.0227783 |
| PARD3B | par-3 family cell polarity regulator beta | -0.0227646 |
| RPL36 | ribosomal protein L36 | -0.022387 |
| RPL7A | ribosomal protein L7a | -0.0222266 |
| UBE3C | ubiquitin protein ligase E3C | -0.022157 |
| RSF1 | remodeling and spacing factor 1 | -0.0216968 |
| PTGES3 | prostaglandin E synthase 3 (cytosolic) | -0.0214724 |
| UBE2K | ubiquitin-conjugating enzyme E2K | -0.0210927 |
| NDRG1 | N-myc downstream regulated 1 | -0.0210834 |
| RPL32 | ribosomal protein L32 | -0.0209223 |
| MYL12B | myosin, light chain 12B, regulatory | -0.0209049 |
| HS6ST2 | heparan sulfate 6-O-sulfotransferase 2 | -0.0208804 |
| RPS25 | ribosomal protein S25 | -0.0203932 |
| ACTG1 | actin gamma 1 | -0.0203813 |
| ROBO1 | roundabout, axon guidance receptor, homolog 1 (Drosophila) | -0.0203472 |
| CDH4 | cadherin 4, type 1, R-cadherin (retinal) | -0.02033 |
| B4GALT5 | UDP-Gal:betaGlcNAc beta 1,4- galactosyltransferase, polypeptide 5 | -0.0199904 |
| TFPI2 | tissue factor pathway inhibitor 2 | -0.0198751 |
| RPS27A | ribosomal protein S27a | -0.0198531 |
| MYO10 | myosin X | -0.0196521 |
| CAMTA1 | calmodulin binding transcription activator 1 | -0.0196185 |
| APOE | apolipoprotein E | -0.0195766 |
| TFRC | transferrin receptor | -0.019174 |
| FTL | ferritin, light polypeptide | -0.019173 |
| RPL36A | ribosomal protein L36a | -0.0191167 |
| ZCCHC7 | zinc finger, CCHC domain containing 7 | -0.0190654 |
| NXN | nucleoredoxin | -0.0190282 |
| CAP1 | CAP, adenylate cyclase-associated protein 1 (yeast) | -0.0188613 |
| RSL1D1 | ribosomal L1 domain containing 1 | -0.0187415 |
| SSH2 | slingshot protein phosphatase 2 | -0.0186213 |
| CHD7 | chromodomain helicase DNA binding protein 7 | -0.0186151 |
| KDM2A | lysine (K)-specific demethylase 2A | -0.0184512 |
| NAV3 | neuron navigator 3 | -0.0184033 |
| DDIT4 | DNA-damage-inducible transcript 4 | -0.0183492 |
| IGF2BP2 | insulin-like growth factor 2 mRNA binding protein 2 | -0.0183319 |
| TARS1 | threonyl-tRNA synthetase 1 | -0.0182201 |
| HNRNPR | heterogeneous nuclear ribonucleoprotein R | -0.0182124 |
| ZFP36L1 | ZFP36 ring finger protein-like 1 | -0.0181829 |
| TMEM135 | transmembrane protein 135 | -0.0181708 |
| NOP58 | NOP58 ribonucleoprotein | -0.0181104 |
| ATXN2 | ataxin 2 | -0.0179684 |
| PA2G4 | proliferation-associated 2G4, 38kDa | -0.0177091 |
| RPS11 | ribosomal protein S11 | -0.0176783 |
| ATP9A | ATPase, class II, type 9A | -0.017634 |
