| Dataset | Tahoe Therapeutics Tahoe 100M Perturbation Atlas |
| Category | transcriptomics |
| Type | cell type |
| Description | Esmolol (hydrochloride) perturbation in RKO cell line (Tahoe Therapeutics) |
| Similar Terms | |
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200 genes differentially expressed following the Esmolol (hydrochloride)_RKO drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| PABPC1 | poly(A) binding protein, cytoplasmic 1 | 0.19886 |
| POTEF | POTE ankyrin domain family, member F | 0.116208 |
| SRRM2 | serine/arginine repetitive matrix 2 | 0.10419 |
| SERPINE1 | serpin peptidase inhibitor, clade E (nexin, plasminogen activator inhibitor type 1), member 1 | 0.102633 |
| FLNB | filamin B, beta | 0.102348 |
| MCL1 | myeloid cell leukemia 1 | 0.101986 |
| ACTG1 | actin gamma 1 | 0.0903917 |
| EEF2 | eukaryotic translation elongation factor 2 | 0.0875852 |
| ENO1 | enolase 1, (alpha) | 0.0869901 |
| GAPDH | glyceraldehyde-3-phosphate dehydrogenase | 0.0866423 |
| NAV2 | neuron navigator 2 | 0.0813815 |
| P4HB | prolyl 4-hydroxylase, beta polypeptide | 0.0759884 |
| RPL3 | ribosomal protein L3 | 0.0709537 |
| GBE1 | glucan (1,4-alpha-), branching enzyme 1 | 0.0676821 |
| UAP1 | UDP-N-acetylglucosamine pyrophosphorylase 1 | 0.0676223 |
| HSP90AA1 | heat shock protein 90kDa alpha (cytosolic), class A member 1 | 0.0673109 |
| EXT1 | exostosin glycosyltransferase 1 | 0.0662427 |
| HSP90AB1 | heat shock protein 90kDa alpha (cytosolic), class B member 1 | 0.065811 |
| RAD51B | RAD51 paralog B | 0.0616615 |
| APLP2 | amyloid beta (A4) precursor-like protein 2 | 0.0611195 |
| JMJD1C | jumonji domain containing 1C | 0.0588039 |
| IMMP2L | IMP2 inner mitochondrial membrane peptidase-like (S. cerevisiae) | 0.058586 |
| ABL2 | ABL proto-oncogene 2, non-receptor tyrosine kinase | 0.0583904 |
| PHC2 | polyhomeotic homolog 2 (Drosophila) | 0.0583903 |
| PBX3 | pre-B-cell leukemia homeobox 3 | 0.0569597 |
| ASPH | aspartate beta-hydroxylase | 0.0566817 |
| NAV3 | neuron navigator 3 | 0.0561396 |
| KTN1 | kinectin 1 (kinesin receptor) | 0.0560138 |
| PHLDA1 | pleckstrin homology-like domain, family A, member 1 | 0.0559182 |
| SHC1 | SHC (Src homology 2 domain containing) transforming protein 1 | 0.054801 |
| ANKRD17 | ankyrin repeat domain 17 | 0.0522589 |
| NDRG1 | N-myc downstream regulated 1 | 0.0517667 |
| DGKI | diacylglycerol kinase, iota | 0.050955 |
| CD68 | CD68 molecule | 0.0502612 |
| LPP | LIM domain containing preferred translocation partner in lipoma | 0.0491797 |
| ASAP1 | ArfGAP with SH3 domain, ankyrin repeat and PH domain 1 | 0.0485206 |
| PSME4 | proteasome (prosome, macropain) activator subunit 4 | 0.0481393 |
| SHANK1 | SH3 and multiple ankyrin repeat domains 1 | 0.0459502 |
| EEF1G | eukaryotic translation elongation factor 1 gamma | 0.0450353 |
| MAPKAP1 | mitogen-activated protein kinase associated protein 1 | 0.0448631 |
| LOC112694756 | uncharaterized LOC112694756 | 0.0447954 |
| TTR | transthyretin | 0.044249 |
| AKAP9 | A kinase (PRKA) anchor protein 9 | 0.0440968 |
| HMGA1 | high mobility group AT-hook 1 | 0.0426201 |
| APP | amyloid beta (A4) precursor protein | 0.0417095 |
| SPTAN1 | spectrin, alpha, non-erythrocytic 1 | 0.0413224 |
| FRMD6 | FERM domain containing 6 | 0.0408575 |
| ITPR3 | inositol 1,4,5-trisphosphate receptor, type 3 | 0.0407724 |
| MMAB | methylmalonic aciduria (cobalamin deficiency) cblB type | 0.0405608 |
| MYH9 | myosin, heavy chain 9, non-muscle | 0.0401156 |
| CAPRIN2 | caprin family member 2 | 0.0399351 |
| FOSL1 | FOS-like antigen 1 | 0.0396069 |
| LDHA | lactate dehydrogenase A | 0.0395679 |
| ZFP36L1 | ZFP36 ring finger protein-like 1 | 0.0393584 |
| GLRX | glutaredoxin (thioltransferase) | 0.0393074 |
| PTPN1 | protein tyrosine phosphatase, non-receptor type 1 | 0.0392948 |
| RBPJ | recombination signal binding protein for immunoglobulin kappa J region | 0.0391871 |
| PCBP2 | poly(rC) binding protein 2 | 0.0388553 |
| MACF1 | microtubule-actin crosslinking factor 1 | 0.0387979 |
| EGR1 | early growth response 1 | 0.0384533 |
| UBA6 | ubiquitin-like modifier activating enzyme 6 | 0.0383114 |
| PDIA3 | protein disulfide isomerase family A, member 3 | 0.0380765 |
| SMTN | smoothelin | 0.0370386 |
| CRIM1 | cysteine rich transmembrane BMP regulator 1 (chordin-like) | 0.0370044 |
| MAST4 | microtubule associated serine/threonine kinase family member 4 | 0.0368202 |
| EXOC4 | exocyst complex component 4 | 0.0365458 |
| ARHGAP22 | Rho GTPase activating protein 22 | 0.0362092 |
| ENO2 | enolase 2 (gamma, neuronal) | 0.0356797 |
| PRRC2C | proline-rich coiled-coil 2C | 0.0356301 |
| STC1 | stanniocalcin 1 | 0.0354501 |
| FAM120A | family with sequence similarity 120A | 0.0353759 |
| BRD2 | bromodomain containing 2 | 0.0349862 |
| HSPA9 | heat shock 70kDa protein 9 (mortalin) | 0.0346242 |
| KMT2E | lysine (K)-specific methyltransferase 2E | 0.0346051 |
| CORO1C | coronin, actin binding protein, 1C | 0.0343112 |
| AXL | AXL receptor tyrosine kinase | 0.0342726 |
| FHIT | fragile histidine triad | 0.0337845 |
| FRMD4A | FERM domain containing 4A | 0.0337689 |
| SLC38A2 | solute carrier family 38, member 2 | 0.033668 |
| MCTP1 | multiple C2 domains, transmembrane 1 | 0.0335008 |
| BRD4 | bromodomain containing 4 | 0.0329973 |
| ELL2 | elongation factor, RNA polymerase II, 2 | 0.0329743 |
| GOLGA4 | golgin A4 | 0.0322591 |
| PPP3CA | protein phosphatase 3, catalytic subunit, alpha isozyme | 0.0322064 |
| PDIA6 | protein disulfide isomerase family A, member 6 | 0.0321156 |
| VPS13B | vacuolar protein sorting 13 homolog B (yeast) | 0.032072 |
| RPS6 | ribosomal protein S6 | 0.0320184 |
| COL27A1 | collagen, type XXVII, alpha 1 | 0.0318087 |
| EFL1 | elongation factor like GTPase 1 | 0.0316191 |
| PKM | pyruvate kinase, muscle | 0.0314908 |
| ZNF438 | zinc finger protein 438 | 0.0314848 |
| ANO6 | anoctamin 6 | 0.0314483 |
| CALD1 | caldesmon 1 | 0.0313176 |
| MYCBP2 | MYC binding protein 2, E3 ubiquitin protein ligase | 0.0312826 |
| EIF2AK2 | eukaryotic translation initiation factor 2-alpha kinase 2 | 0.0312755 |
| EIF4G1 | eukaryotic translation initiation factor 4 gamma, 1 | 0.0312692 |
| SET | SET nuclear proto-oncogene | 0.0309513 |
| FLNA | filamin A, alpha | 0.030944 |
| WDR43 | WD repeat domain 43 | 0.030904 |
| PGK1 | phosphoglycerate kinase 1 | 0.0305536 |
| Symbol | Name | Standardized Value |
|---|---|---|
| HSPA5 | heat shock 70kDa protein 5 (glucose-regulated protein, 78kDa) | -0.200102 |
| RPLP1 | ribosomal protein, large, P1 | -0.054927 |
| RPS24 | ribosomal protein S24 | -0.0509314 |
| RPL35A | ribosomal protein L35a | -0.0498759 |
| TPT1 | tumor protein, translationally-controlled 1 | -0.0465543 |
| KDM3A | lysine (K)-specific demethylase 3A | -0.0408233 |
| RPL12 | ribosomal protein L12 | -0.0374903 |
| NAP1L1 | nucleosome assembly protein 1-like 1 | -0.0359735 |
| RPS27A | ribosomal protein S27a | -0.0314805 |
| RAD21 | RAD21 homolog (S. pombe) | -0.0311931 |
| RPL4 | ribosomal protein L4 | -0.0304388 |
| RPL38 | ribosomal protein L38 | -0.0282789 |
| HNRNPU | heterogeneous nuclear ribonucleoprotein U (scaffold attachment factor A) | -0.0280203 |
| CAP1 | CAP, adenylate cyclase-associated protein 1 (yeast) | -0.0277837 |
| RPL34 | ribosomal protein L34 | -0.0275905 |
| TXNRD1 | thioredoxin reductase 1 | -0.0274108 |
| RPL32 | ribosomal protein L32 | -0.0269658 |
| PTMA | prothymosin, alpha | -0.0263546 |
| RPL6 | ribosomal protein L6 | -0.0252876 |
| RPL7 | ribosomal protein L7 | -0.0251983 |
| RPL31 | ribosomal protein L31 | -0.0246036 |
| MATR3 | matrin 3 | -0.0245445 |
| SSR3 | signal sequence receptor, gamma (translocon-associated protein gamma) | -0.0242247 |
| EIF3E | eukaryotic translation initiation factor 3, subunit E | -0.0241516 |
| ARL6IP1 | ADP-ribosylation factor-like 6 interacting protein 1 | -0.0226571 |
| SLC25A36 | solute carrier family 25 (pyrimidine nucleotide carrier), member 36 | -0.0226373 |
| ACSL4 | acyl-CoA synthetase long-chain family member 4 | -0.0223748 |
| NIPBL | Nipped-B homolog (Drosophila) | -0.0222425 |
| TMSB10 | thymosin beta 10 | -0.0219615 |
| SENP5 | SUMO1/sentrin specific peptidase 5 | -0.0217137 |
| RRBP1 | ribosome binding protein 1 | -0.0212512 |
| SF3B2 | splicing factor 3b, subunit 2, 145kDa | -0.0208894 |
| ARF1 | ADP-ribosylation factor 1 | -0.0207452 |
| HNRNPAB | heterogeneous nuclear ribonucleoprotein A/B | -0.0205633 |
| MON2 | MON2 homolog (S. cerevisiae) | -0.0202605 |
| NPM1 | nucleophosmin (nucleolar phosphoprotein B23, numatrin) | -0.0202108 |
| CAMTA1 | calmodulin binding transcription activator 1 | -0.020065 |
| RPS20 | ribosomal protein S20 | -0.0200205 |
| SCLT1 | sodium channel and clathrin linker 1 | -0.0196484 |
| DDX3X | DEAD (Asp-Glu-Ala-Asp) box helicase 3, X-linked | -0.0196429 |
| RPL36A | ribosomal protein L36a | -0.0196332 |
| CD63 | CD63 molecule | -0.0195086 |
| PPP2CA | protein phosphatase 2, catalytic subunit, alpha isozyme | -0.0194644 |
| TBCA | tubulin folding cofactor A | -0.01885 |
| RSL1D1 | ribosomal L1 domain containing 1 | -0.0187218 |
| RPS25 | ribosomal protein S25 | -0.0186721 |
| DLC1 | DLC1 Rho GTPase activating protein | -0.0180022 |
| GARS1 | glycyl-tRNA synthetase 1 | -0.0179891 |
| RNF168 | ring finger protein 168, E3 ubiquitin protein ligase | -0.0175745 |
| HNRNPH1 | heterogeneous nuclear ribonucleoprotein H1 (H) | -0.0175224 |
| VDAC1 | voltage-dependent anion channel 1 | -0.0172389 |
| RHEB | Ras homolog enriched in brain | -0.0169069 |
| MARCHF6 | membrane associated ring-CH-type finger 6 | -0.0168803 |
| RPL41 | ribosomal protein L41 | -0.0168689 |
| RPLP2 | ribosomal protein, large, P2 | -0.0167867 |
| SBF2 | SET binding factor 2 | -0.0167264 |
| SRP72 | signal recognition particle 72kDa | -0.0165399 |
| RPL36AL | ribosomal protein L36a-like | -0.0164664 |
| RPS29 | ribosomal protein S29 | -0.0164479 |
| RPL14 | ribosomal protein L14 | -0.0163528 |
| CCDC47 | coiled-coil domain containing 47 | -0.01616 |
| AP3B1 | adaptor-related protein complex 3, beta 1 subunit | -0.0160915 |
| PSMB7 | proteasome (prosome, macropain) subunit, beta type, 7 | -0.0160877 |
| GNL3 | guanine nucleotide binding protein-like 3 (nucleolar) | -0.0160716 |
| STAU1 | staufen double-stranded RNA binding protein 1 | -0.0160496 |
| G2E3 | G2/M-phase specific E3 ubiquitin protein ligase | -0.0159305 |
| ARFGEF2 | ADP-ribosylation factor guanine nucleotide-exchange factor 2 (brefeldin A-inhibited) | -0.0155205 |
| EIF1 | eukaryotic translation initiation factor 1 | -0.0154078 |
| WDR45B | WD repeat domain 45B | -0.0153613 |
| NPR2 | natriuretic peptide receptor 2 | -0.0153171 |
| PPP2R2A | protein phosphatase 2, regulatory subunit B, alpha | -0.0153011 |
| EDF1 | endothelial differentiation-related factor 1 | -0.0152674 |
| PPP6R3 | protein phosphatase 6, regulatory subunit 3 | -0.0152433 |
| ARPC2 | actin related protein 2/3 complex, subunit 2, 34kDa | -0.0150088 |
| ZNF544 | zinc finger protein 544 | -0.0148546 |
| RPL37A | ribosomal protein L37a | -0.014854 |
| TPTEP2-CSNK1E | TPTEP2-CSNK1E readthrough | -0.0147448 |
| MYSM1 | Myb-like, SWIRM and MPN domains 1 | -0.0146949 |
| S100A2 | S100 calcium binding protein A2 | -0.0145939 |
| PARK7 | parkinson protein 7 | -0.0145276 |
| STARD7 | StAR-related lipid transfer (START) domain containing 7 | -0.0145221 |
| CHCHD2 | coiled-coil-helix-coiled-coil-helix domain containing 2 | -0.0145062 |
| EEF1D | eukaryotic translation elongation factor 1 delta (guanine nucleotide exchange protein) | -0.0144853 |
| RPS21 | ribosomal protein S21 | -0.014459 |
| ANKRD11 | ankyrin repeat domain 11 | -0.0141872 |
| TARS1 | threonyl-tRNA synthetase 1 | -0.0138328 |
| HMGB2 | high mobility group box 2 | -0.0137879 |
| LARP4B | La ribonucleoprotein domain family, member 4B | -0.0137524 |
| STK4 | serine/threonine kinase 4 | -0.0136072 |
| RPS15A | ribosomal protein S15a | -0.0135891 |
| CDK12 | cyclin-dependent kinase 12 | -0.0133908 |
| SELENOK | selenoprotein K | -0.0133354 |
| MT2A | metallothionein 2A | -0.0133284 |
| SAFB2 | scaffold attachment factor B2 | -0.0130887 |
| RLF | rearranged L-myc fusion | -0.0130886 |
| C2CD2 | C2 calcium-dependent domain containing 2 | -0.0130728 |
| MRPL13 | mitochondrial ribosomal protein L13 | -0.0130367 |
| RPL27A | ribosomal protein L27a | -0.0128604 |
| MEAF6 | MYST/Esa1-associated factor 6 | -0.0128134 |
| TEX10 | testis expressed 10 | -0.0124871 |
