| Dataset | Tahoe Therapeutics Tahoe 100M Perturbation Atlas |
| Category | transcriptomics |
| Type | cell type |
| Description | Esmolol (hydrochloride) perturbation in SNU-423 cell line (Tahoe Therapeutics) |
| Similar Terms | |
| Downloads & Tools |
200 genes differentially expressed following the Esmolol (hydrochloride)_SNU-423 drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| FN1 | fibronectin 1 | 0.241987 |
| FTH1 | ferritin, heavy polypeptide 1 | 0.143961 |
| GLIS3 | GLIS family zinc finger 3 | 0.115163 |
| FNDC3B | fibronectin type III domain containing 3B | 0.107722 |
| COL6A3 | collagen, type VI, alpha 3 | 0.107492 |
| PDE10A | phosphodiesterase 10A | 0.106141 |
| FRMD4A | FERM domain containing 4A | 0.104206 |
| VCL | vinculin | 0.0912585 |
| AKAP12 | A kinase (PRKA) anchor protein 12 | 0.0909645 |
| BICC1 | BicC family RNA binding protein 1 | 0.0886521 |
| C3 | complement component 3 | 0.0885116 |
| VCAN | versican | 0.0885042 |
| VEGFA | vascular endothelial growth factor A | 0.0834583 |
| CD44 | CD44 molecule (Indian blood group) | 0.0805698 |
| MYH9 | myosin, heavy chain 9, non-muscle | 0.0798674 |
| SMAD3 | SMAD family member 3 | 0.0795499 |
| TANC2 | tetratricopeptide repeat, ankyrin repeat and coiled-coil containing 2 | 0.0790601 |
| IQCJ-SCHIP1 | IQCJ-SCHIP1 readthrough | 0.0788374 |
| SFTPA2 | surfactant protein A2 | 0.0726307 |
| TGFBI | transforming growth factor, beta-induced, 68kDa | 0.0720308 |
| TRIO | trio Rho guanine nucleotide exchange factor | 0.0697168 |
| HLA-A | major histocompatibility complex, class I, A | 0.0690122 |
| GRIN2A | glutamate receptor, ionotropic, N-methyl D-aspartate 2A | 0.0682062 |
| HDAC9 | histone deacetylase 9 | 0.0679201 |
| AGAP1 | ArfGAP with GTPase domain, ankyrin repeat and PH domain 1 | 0.0666939 |
| EDIL3 | EGF-like repeats and discoidin I-like domains 3 | 0.0654022 |
| TNS3 | tensin 3 | 0.0639606 |
| MAGI2 | membrane associated guanylate kinase, WW and PDZ domain containing 2 | 0.0633081 |
| LRRFIP1 | leucine rich repeat (in FLII) interacting protein 1 | 0.0630807 |
| EXT1 | exostosin glycosyltransferase 1 | 0.0623161 |
| DST | dystonin | 0.0611707 |
| ATXN1 | ataxin 1 | 0.0611278 |
| ITGA3 | integrin, alpha 3 (antigen CD49C, alpha 3 subunit of VLA-3 receptor) | 0.0591237 |
| NDRG1 | N-myc downstream regulated 1 | 0.058976 |
| GAPDH | glyceraldehyde-3-phosphate dehydrogenase | 0.0585346 |
| IMMP2L | IMP2 inner mitochondrial membrane peptidase-like (S. cerevisiae) | 0.0571007 |
| DCBLD2 | discoidin, CUB and LCCL domain containing 2 | 0.0568548 |
| MSN | moesin | 0.0558375 |
| BNIP3 | BCL2/adenovirus E1B 19kDa interacting protein 3 | 0.0549061 |
| SPARC | secreted protein, acidic, cysteine-rich (osteonectin) | 0.0548722 |
| IGFBP3 | insulin-like growth factor binding protein 3 | 0.0544837 |
| RNF213 | ring finger protein 213 | 0.0536104 |
| ABCA1 | ATP-binding cassette, sub-family A (ABC1), member 1 | 0.0522602 |
| FLNB | filamin B, beta | 0.0520699 |
| KCNMA1 | potassium channel, calcium activated large conductance subfamily M alpha, member 1 | 0.0520676 |
| NHS | Nance-Horan syndrome (congenital cataracts and dental anomalies) | 0.0487769 |
| EGR1 | early growth response 1 | 0.0476555 |
| TENT5A | terminal nucleotidyltransferase 5A | 0.0472186 |
| DSCAM | Down syndrome cell adhesion molecule | 0.0450532 |
| NR3C1 | nuclear receptor subfamily 3, group C, member 1 (glucocorticoid receptor) | 0.044886 |
| HLA-B | major histocompatibility complex, class I, B | 0.044588 |
| NAV1 | neuron navigator 1 | 0.0444241 |
| KYNU | kynureninase | 0.0442442 |
| SLC38A2 | solute carrier family 38, member 2 | 0.0436294 |
| LDHA | lactate dehydrogenase A | 0.0434472 |
| APLP2 | amyloid beta (A4) precursor-like protein 2 | 0.0432983 |
| HIVEP2 | human immunodeficiency virus type I enhancer binding protein 2 | 0.0430011 |
| NABP1 | nucleic acid binding protein 1 | 0.0424149 |
| GBE1 | glucan (1,4-alpha-), branching enzyme 1 | 0.04208 |
| EPAS1 | endothelial PAS domain protein 1 | 0.0420629 |
| SEPTIN9 | septin 9 | 0.0420477 |
| LOX | lysyl oxidase | 0.0420268 |
| ZMIZ1 | zinc finger, MIZ-type containing 1 | 0.0419977 |
| RBMS3 | RNA binding motif, single stranded interacting protein 3 | 0.0408016 |
| JMJD1C | jumonji domain containing 1C | 0.0407814 |
| ZSWIM6 | zinc finger, SWIM-type containing 6 | 0.0402579 |
| VMP1 | vacuole membrane protein 1 | 0.0400703 |
| ZMYND8 | zinc finger, MYND-type containing 8 | 0.0397424 |
| PPARD | peroxisome proliferator-activated receptor delta | 0.0395299 |
| ZHX2 | zinc fingers and homeoboxes 2 | 0.0385262 |
| COL6A2 | collagen, type VI, alpha 2 | 0.0383222 |
| P4HB | prolyl 4-hydroxylase, beta polypeptide | 0.0380265 |
| SDK1 | sidekick cell adhesion molecule 1 | 0.037922 |
| RPS2 | ribosomal protein S2 | 0.037453 |
| MYOF | myoferlin | 0.0360313 |
| SRRM2 | serine/arginine repetitive matrix 2 | 0.0350807 |
| EGFR | epidermal growth factor receptor | 0.0350379 |
| PALM2AKAP2 | PALM2 and AKAP2 fusion | 0.0347813 |
| RAD51B | RAD51 paralog B | 0.0334501 |
| COL5A1 | collagen, type V, alpha 1 | 0.0333804 |
| ARFGEF3 | ARFGEF family member 3 | 0.0333749 |
| STC2 | stanniocalcin 2 | 0.0333169 |
| LOXL2 | lysyl oxidase-like 2 | 0.0326159 |
| RPS6 | ribosomal protein S6 | 0.0322798 |
| LPP | LIM domain containing preferred translocation partner in lipoma | 0.0320649 |
| PAPPA | pregnancy-associated plasma protein A, pappalysin 1 | 0.0318503 |
| ADAM12 | ADAM metallopeptidase domain 12 | 0.031754 |
| ZBTB20 | zinc finger and BTB domain containing 20 | 0.0314021 |
| SPTBN1 | spectrin, beta, non-erythrocytic 1 | 0.0312506 |
| PLOD2 | procollagen-lysine, 2-oxoglutarate 5-dioxygenase 2 | 0.0309954 |
| HMGA2 | high mobility group AT-hook 2 | 0.0309851 |
| ITPR3 | inositol 1,4,5-trisphosphate receptor, type 3 | 0.030535 |
| TFPI | tissue factor pathway inhibitor (lipoprotein-associated coagulation inhibitor) | 0.0301366 |
| ETS1 | v-ets avian erythroblastosis virus E26 oncogene homolog 1 | 0.0299827 |
| LOC112694756 | uncharaterized LOC112694756 | 0.0299365 |
| BRD2 | bromodomain containing 2 | 0.029773 |
| MAML2 | mastermind-like 2 (Drosophila) | 0.0296685 |
| SHB | Src homology 2 domain containing adaptor protein B | 0.0295523 |
| CITED2 | Cbp/p300-interacting transactivator, with Glu/Asp-rich carboxy-terminal domain, 2 | 0.0295484 |
| GOLGB1 | golgin B1 | 0.0293779 |
| Symbol | Name | Standardized Value |
|---|---|---|
| TMSB10 | thymosin beta 10 | -0.0994217 |
| IER3 | immediate early response 3 | -0.0735182 |
| HSPA5 | heat shock 70kDa protein 5 (glucose-regulated protein, 78kDa) | -0.0716855 |
| RPS24 | ribosomal protein S24 | -0.0705751 |
| VIM | vimentin | -0.0644856 |
| PTMA | prothymosin, alpha | -0.061508 |
| FTL | ferritin, light polypeptide | -0.0528408 |
| NPM1 | nucleophosmin (nucleolar phosphoprotein B23, numatrin) | -0.0463748 |
| TOP2A | topoisomerase (DNA) II alpha 170kDa | -0.037924 |
| KDM3A | lysine (K)-specific demethylase 3A | -0.0356893 |
| RPS27A | ribosomal protein S27a | -0.0352454 |
| TKT | transketolase | -0.0348142 |
| RPL35A | ribosomal protein L35a | -0.0341568 |
| RPL23 | ribosomal protein L23 | -0.0337077 |
| PNRC1 | proline-rich nuclear receptor coactivator 1 | -0.0328091 |
| MATR3 | matrin 3 | -0.0317273 |
| CALM2 | calmodulin 2 (phosphorylase kinase, delta) | -0.0315594 |
| HNRNPU | heterogeneous nuclear ribonucleoprotein U (scaffold attachment factor A) | -0.0315401 |
| RPLP1 | ribosomal protein, large, P1 | -0.0305361 |
| ANLN | anillin, actin binding protein | -0.0291912 |
| ITGB1 | integrin, beta 1 (fibronectin receptor, beta polypeptide, antigen CD29 includes MDF2, MSK12) | -0.0290273 |
| NAP1L1 | nucleosome assembly protein 1-like 1 | -0.0289773 |
| UBC | ubiquitin C | -0.0263791 |
| ERO1A | endoplasmic reticulum oxidoreductase 1 alpha | -0.026291 |
| AHNAK | AHNAK nucleoprotein | -0.0261124 |
| TPT1 | tumor protein, translationally-controlled 1 | -0.0248328 |
| TXNRD1 | thioredoxin reductase 1 | -0.0246575 |
| TFG | TRK-fused gene | -0.0239188 |
| ARL6IP1 | ADP-ribosylation factor-like 6 interacting protein 1 | -0.0238724 |
| KIF4A | kinesin family member 4A | -0.0232123 |
| NUCKS1 | nuclear casein kinase and cyclin-dependent kinase substrate 1 | -0.0227507 |
| TMEM123 | transmembrane protein 123 | -0.0226872 |
| RPS23 | ribosomal protein S23 | -0.0225703 |
| HNRNPH1 | heterogeneous nuclear ribonucleoprotein H1 (H) | -0.022291 |
| SF3B2 | splicing factor 3b, subunit 2, 145kDa | -0.0214417 |
| ACSL3 | acyl-CoA synthetase long-chain family member 3 | -0.0213742 |
| YWHAZ | tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, zeta | -0.0213202 |
| RPL32 | ribosomal protein L32 | -0.0212644 |
| CENPF | centromere protein F, 350/400kDa | -0.0208352 |
| MARCHF6 | membrane associated ring-CH-type finger 6 | -0.0207371 |
| RPL31 | ribosomal protein L31 | -0.020613 |
| SLC25A36 | solute carrier family 25 (pyrimidine nucleotide carrier), member 36 | -0.0206085 |
| HNRNPA2B1 | heterogeneous nuclear ribonucleoprotein A2/B1 | -0.0204354 |
| HSPA9 | heat shock 70kDa protein 9 (mortalin) | -0.0200595 |
| SRGN | serglycin | -0.0199861 |
| MKI67 | marker of proliferation Ki-67 | -0.0196067 |
| RBM39 | RNA binding motif protein 39 | -0.0193192 |
| AP3B1 | adaptor-related protein complex 3, beta 1 subunit | -0.0193113 |
| ARFGEF2 | ADP-ribosylation factor guanine nucleotide-exchange factor 2 (brefeldin A-inhibited) | -0.0193075 |
| GARS1 | glycyl-tRNA synthetase 1 | -0.0190796 |
| WTAP | Wilms tumor 1 associated protein | -0.0189965 |
| TPX2 | TPX2, microtubule-associated | -0.0189353 |
| PRKDC | protein kinase, DNA-activated, catalytic polypeptide | -0.0188883 |
| HSP90AA1 | heat shock protein 90kDa alpha (cytosolic), class A member 1 | -0.0187848 |
| VPS26A | vacuolar protein sorting 26 homolog A (S. pombe) | -0.0186798 |
| RPLP2 | ribosomal protein, large, P2 | -0.0183779 |
| ANXA2 | annexin A2 | -0.0180826 |
| NT5C2 | 5'-nucleotidase, cytosolic II | -0.0180352 |
| MAP3K2 | mitogen-activated protein kinase kinase kinase 2 | -0.017646 |
| RPL4 | ribosomal protein L4 | -0.017624 |
| HIF1A | hypoxia inducible factor 1, alpha subunit (basic helix-loop-helix transcription factor) | -0.017527 |
| FXR1 | fragile X mental retardation, autosomal homolog 1 | -0.0174866 |
| LCORL | ligand dependent nuclear receptor corepressor-like | -0.0173229 |
| PJA2 | praja ring finger 2, E3 ubiquitin protein ligase | -0.0172629 |
| EPS8 | epidermal growth factor receptor pathway substrate 8 | -0.0172228 |
| TM4SF1 | transmembrane 4 L six family member 1 | -0.0168896 |
| CALR | calreticulin | -0.0168091 |
| SPAG9 | sperm associated antigen 9 | -0.0167966 |
| RPL14 | ribosomal protein L14 | -0.016726 |
| CALM1 | calmodulin 1 (phosphorylase kinase, delta) | -0.0164952 |
| CCT8 | chaperonin containing TCP1, subunit 8 (theta) | -0.0164226 |
| USP3 | ubiquitin specific peptidase 3 | -0.0164218 |
| HMGB2 | high mobility group box 2 | -0.0163461 |
| DEK | DEK proto-oncogene | -0.0163318 |
| RPL34 | ribosomal protein L34 | -0.0162769 |
| FMR1 | fragile X mental retardation 1 | -0.0161623 |
| NPR2 | natriuretic peptide receptor 2 | -0.0161459 |
| RPS5 | ribosomal protein S5 | -0.0160256 |
| YWHAB | tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, beta | -0.0159088 |
| SEPTIN7 | septin 7 | -0.0156702 |
| G3BP1 | GTPase activating protein (SH3 domain) binding protein 1 | -0.0156665 |
| PRR11 | proline rich 11 | -0.0156178 |
| ZFAND3 | zinc finger, AN1-type domain 3 | -0.0155571 |
| SMG1 | SMG1 phosphatidylinositol 3-kinase-related kinase | -0.0155569 |
| MT2A | metallothionein 2A | -0.0155067 |
| COPB2 | coatomer protein complex, subunit beta 2 (beta prime) | -0.0151295 |
| OLA1 | Obg-like ATPase 1 | -0.0150452 |
| HSP90B1 | heat shock protein 90kDa beta (Grp94), member 1 | -0.0149695 |
| CKAP2 | cytoskeleton associated protein 2 | -0.0149195 |
| RPLP0 | ribosomal protein, large, P0 | -0.0147041 |
| QKI | QKI, KH domain containing, RNA binding | -0.0147017 |
| UVRAG | UV radiation resistance associated | -0.0146766 |
| SEC11A | SEC11 homolog A (S. cerevisiae) | -0.0145662 |
| CKAP5 | cytoskeleton associated protein 5 | -0.0145207 |
| CCT6A | chaperonin containing TCP1, subunit 6A (zeta 1) | -0.0145136 |
| PSMD14 | proteasome (prosome, macropain) 26S subunit, non-ATPase, 14 | -0.0145094 |
| PDPK1 | 3-phosphoinositide dependent protein kinase 1 | -0.0142811 |
| ZNF207 | zinc finger protein 207 | -0.0140251 |
| HSPD1 | heat shock 60kDa protein 1 (chaperonin) | -0.0139325 |
| PKM | pyruvate kinase, muscle | -0.0138901 |
