| Dataset | Tahoe Therapeutics Tahoe 100M Perturbation Atlas |
| Category | transcriptomics |
| Type | cell type |
| Description | Esmolol (hydrochloride) perturbation in SW 1271 cell line (Tahoe Therapeutics) |
| Similar Terms | |
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200 genes differentially expressed following the Esmolol (hydrochloride)_SW 1271 drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| FNDC3B | fibronectin type III domain containing 3B | 0.182733 |
| GAPDH | glyceraldehyde-3-phosphate dehydrogenase | 0.175694 |
| LDHA | lactate dehydrogenase A | 0.0934615 |
| UACA | uveal autoantigen with coiled-coil domains and ankyrin repeats | 0.0773018 |
| DST | dystonin | 0.0661239 |
| CD44 | CD44 molecule (Indian blood group) | 0.0649089 |
| SMAD3 | SMAD family member 3 | 0.0608851 |
| LOC112694756 | uncharaterized LOC112694756 | 0.0586528 |
| PALM2AKAP2 | PALM2 and AKAP2 fusion | 0.0579264 |
| ZC3HAV1 | zinc finger CCCH-type, antiviral 1 | 0.057534 |
| RAD51B | RAD51 paralog B | 0.0574731 |
| PHLDB2 | pleckstrin homology-like domain, family B, member 2 | 0.0569967 |
| DNER | delta/notch-like EGF repeat containing | 0.0569813 |
| BASP1 | brain abundant, membrane attached signal protein 1 | 0.0562767 |
| NEDD4 | neural precursor cell expressed, developmentally down-regulated 4, E3 ubiquitin protein ligase | 0.0556237 |
| FTH1 | ferritin, heavy polypeptide 1 | 0.0554597 |
| TRIO | trio Rho guanine nucleotide exchange factor | 0.0542959 |
| AKAP13 | A kinase (PRKA) anchor protein 13 | 0.0497719 |
| ANKRD28 | ankyrin repeat domain 28 | 0.0491281 |
| ZSWIM6 | zinc finger, SWIM-type containing 6 | 0.0489286 |
| ZBTB20 | zinc finger and BTB domain containing 20 | 0.0484581 |
| PLOD2 | procollagen-lysine, 2-oxoglutarate 5-dioxygenase 2 | 0.0481526 |
| MACF1 | microtubule-actin crosslinking factor 1 | 0.0481143 |
| ABL1 | ABL proto-oncogene 1, non-receptor tyrosine kinase | 0.0464923 |
| PRKCA | protein kinase C, alpha | 0.0456872 |
| CRIM1 | cysteine rich transmembrane BMP regulator 1 (chordin-like) | 0.0450766 |
| IGFBP3 | insulin-like growth factor binding protein 3 | 0.0448008 |
| DSCAM | Down syndrome cell adhesion molecule | 0.0443772 |
| FMN1 | formin 1 | 0.0441546 |
| PITPNC1 | phosphatidylinositol transfer protein, cytoplasmic 1 | 0.0439392 |
| TAS2R14 | taste receptor, type 2, member 14 | 0.0438359 |
| NALCN | sodium leak channel, non selective | 0.0436984 |
| FMNL2 | formin-like 2 | 0.0433501 |
| UBE2E2 | ubiquitin-conjugating enzyme E2E 2 | 0.0432178 |
| RB1 | retinoblastoma 1 | 0.0430367 |
| FLNB | filamin B, beta | 0.0427062 |
| SH3KBP1 | SH3-domain kinase binding protein 1 | 0.0420525 |
| TM4SF1 | transmembrane 4 L six family member 1 | 0.0419096 |
| KIF5B | kinesin family member 5B | 0.0406936 |
| NAV2 | neuron navigator 2 | 0.0405258 |
| CD55 | CD55 molecule, decay accelerating factor for complement (Cromer blood group) | 0.0399682 |
| YBX3 | Y box binding protein 3 | 0.0397052 |
| PARD3 | par-3 family cell polarity regulator | 0.0396463 |
| PHF3 | PHD finger protein 3 | 0.0394823 |
| MYO9B | myosin IXB | 0.0384819 |
| ATXN1 | ataxin 1 | 0.0380282 |
| ASAP1 | ArfGAP with SH3 domain, ankyrin repeat and PH domain 1 | 0.0377098 |
| HMGA2 | high mobility group AT-hook 2 | 0.0376237 |
| SMURF2 | SMAD specific E3 ubiquitin protein ligase 2 | 0.0370037 |
| KCNMA1 | potassium channel, calcium activated large conductance subfamily M alpha, member 1 | 0.0367568 |
| MAP1B | microtubule-associated protein 1B | 0.0365984 |
| TRPC4AP | transient receptor potential cation channel, subfamily C, member 4 associated protein | 0.0365413 |
| CCDC88A | coiled-coil domain containing 88A | 0.0359825 |
| RALY | RALY heterogeneous nuclear ribonucleoprotein | 0.0356162 |
| JMJD1C | jumonji domain containing 1C | 0.035598 |
| ARHGEF12 | Rho guanine nucleotide exchange factor (GEF) 12 | 0.0355736 |
| ACTG1 | actin gamma 1 | 0.0355524 |
| N4BP2L2 | NEDD4 binding protein 2-like 2 | 0.0354786 |
| PYGL | phosphorylase, glycogen, liver | 0.0353985 |
| ITGB5 | integrin, beta 5 | 0.0350131 |
| SEPTIN9 | septin 9 | 0.0349862 |
| BHLHE40 | basic helix-loop-helix family, member e40 | 0.0346555 |
| ARID1B | AT rich interactive domain 1B (SWI1-like) | 0.0346102 |
| SEMA3C | sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3C | 0.0341765 |
| ABL2 | ABL proto-oncogene 2, non-receptor tyrosine kinase | 0.0339145 |
| SMYD3 | SET and MYND domain containing 3 | 0.0336692 |
| MBNL1 | muscleblind-like splicing regulator 1 | 0.0329383 |
| ACTN1 | actinin, alpha 1 | 0.0327342 |
| DPYD | dihydropyrimidine dehydrogenase | 0.0324731 |
| EHMT1 | euchromatic histone-lysine N-methyltransferase 1 | 0.032457 |
| CLIP1 | CAP-GLY domain containing linker protein 1 | 0.0320257 |
| PCNX4 | pecanex 4 | 0.031959 |
| SLC38A2 | solute carrier family 38, member 2 | 0.03185 |
| ENO1 | enolase 1, (alpha) | 0.031529 |
| RAB7A | RAB7A, member RAS oncogene family | 0.0314749 |
| NCEH1 | neutral cholesterol ester hydrolase 1 | 0.031373 |
| THSD4 | thrombospondin, type I, domain containing 4 | 0.0309935 |
| SDC4 | syndecan 4 | 0.0309335 |
| SDCCAG8 | serologically defined colon cancer antigen 8 | 0.0308999 |
| LPP | LIM domain containing preferred translocation partner in lipoma | 0.0305655 |
| PTK2 | protein tyrosine kinase 2 | 0.03041 |
| MSN | moesin | 0.030179 |
| AKT3 | v-akt murine thymoma viral oncogene homolog 3 | 0.0298306 |
| PACS1 | phosphofurin acidic cluster sorting protein 1 | 0.0298223 |
| KMT2E | lysine (K)-specific methyltransferase 2E | 0.0296991 |
| INTS6 | integrator complex subunit 6 | 0.0296078 |
| EGR1 | early growth response 1 | 0.0295394 |
| GPC6 | glypican 6 | 0.0291417 |
| BICD1 | bicaudal D homolog 1 (Drosophila) | 0.0291232 |
| GNB1 | guanine nucleotide binding protein (G protein), beta polypeptide 1 | 0.0289948 |
| IGF2BP3 | insulin-like growth factor 2 mRNA binding protein 3 | 0.0289109 |
| CAPRIN2 | caprin family member 2 | 0.0288757 |
| ATP13A3 | ATPase type 13A3 | 0.0288181 |
| ATM | ATM serine/threonine kinase | 0.0286848 |
| NCOR1 | nuclear receptor corepressor 1 | 0.0286212 |
| IQGAP1 | IQ motif containing GTPase activating protein 1 | 0.02848 |
| TTC17 | tetratricopeptide repeat domain 17 | 0.0282542 |
| SETD5 | SET domain containing 5 | 0.0281148 |
| SEMA4B | sema domain, immunoglobulin domain (Ig), transmembrane domain (TM) and short cytoplasmic domain, (semaphorin) 4B | 0.0280402 |
| STARD13 | StAR-related lipid transfer (START) domain containing 13 | 0.0280078 |
| Symbol | Name | Standardized Value |
|---|---|---|
| TMSB10 | thymosin beta 10 | -0.0888391 |
| NAMPT | nicotinamide phosphoribosyltransferase | -0.0665239 |
| HSP90AA1 | heat shock protein 90kDa alpha (cytosolic), class A member 1 | -0.0542498 |
| RPLP1 | ribosomal protein, large, P1 | -0.0449476 |
| ZNF292 | zinc finger protein 292 | -0.0430088 |
| PKM | pyruvate kinase, muscle | -0.0422392 |
| GPRC5A | G protein-coupled receptor, class C, group 5, member A | -0.0403394 |
| RPL7 | ribosomal protein L7 | -0.0369404 |
| IPO7 | importin 7 | -0.0359361 |
| SREK1 | splicing regulatory glutamine/lysine-rich protein 1 | -0.0355114 |
| PTMA | prothymosin, alpha | -0.0349239 |
| NPM1 | nucleophosmin (nucleolar phosphoprotein B23, numatrin) | -0.0349173 |
| COLEC11 | collectin sub-family member 11 | -0.0341966 |
| TAF15 | TAF15 RNA polymerase II, TATA box binding protein (TBP)-associated factor, 68kDa | -0.0322868 |
| RPS17 | ribosomal protein S17 | -0.0320532 |
| RPL32 | ribosomal protein L32 | -0.0318865 |
| XPO1 | exportin 1 | -0.0310338 |
| EIF2S2 | eukaryotic translation initiation factor 2, subunit 2 beta, 38kDa | -0.0307793 |
| DIAPH3 | diaphanous-related formin 3 | -0.0307743 |
| TUBA1B | tubulin, alpha 1b | -0.0307533 |
| PJA2 | praja ring finger 2, E3 ubiquitin protein ligase | -0.0307437 |
| NUCKS1 | nuclear casein kinase and cyclin-dependent kinase substrate 1 | -0.0306727 |
| TXNRD1 | thioredoxin reductase 1 | -0.0302382 |
| SLC25A36 | solute carrier family 25 (pyrimidine nucleotide carrier), member 36 | -0.0299017 |
| HSPA9 | heat shock 70kDa protein 9 (mortalin) | -0.0298714 |
| HNRNPA2B1 | heterogeneous nuclear ribonucleoprotein A2/B1 | -0.0296149 |
| RSRC2 | arginine/serine-rich coiled-coil 2 | -0.0294856 |
| S100A9 | S100 calcium binding protein A9 | -0.0281983 |
| RPS23 | ribosomal protein S23 | -0.028008 |
| SLC2A3 | solute carrier family 2 (facilitated glucose transporter), member 3 | -0.0279635 |
| RPL4 | ribosomal protein L4 | -0.027768 |
| HELZ | helicase with zinc finger | -0.0273674 |
| WDR36 | WD repeat domain 36 | -0.0271061 |
| RPL37A | ribosomal protein L37a | -0.0270861 |
| RPL36AL | ribosomal protein L36a-like | -0.0270138 |
| TOMM20 | translocase of outer mitochondrial membrane 20 homolog (yeast) | -0.0263301 |
| PRR11 | proline rich 11 | -0.0262023 |
| FXR1 | fragile X mental retardation, autosomal homolog 1 | -0.0259054 |
| CEP295 | centrosomal protein 295kDa | -0.0259012 |
| CALR | calreticulin | -0.0257925 |
| FUS | FUS RNA binding protein | -0.0257622 |
| DCAF6 | DDB1 and CUL4 associated factor 6 | -0.0255064 |
| RPS29 | ribosomal protein S29 | -0.025289 |
| SERF2 | small EDRK-rich factor 2 | -0.024817 |
| LDHB | lactate dehydrogenase B | -0.0248016 |
| HBP1 | HMG-box transcription factor 1 | -0.024567 |
| PREPL | prolyl endopeptidase-like | -0.0243689 |
| SEC61A1 | Sec61 alpha 1 subunit (S. cerevisiae) | -0.0243666 |
| RPS13 | ribosomal protein S13 | -0.0241571 |
| RPS10 | ribosomal protein S10 | -0.0240432 |
| RPL23 | ribosomal protein L23 | -0.0240159 |
| HSPD1 | heat shock 60kDa protein 1 (chaperonin) | -0.0239813 |
| ADAM17 | ADAM metallopeptidase domain 17 | -0.0238642 |
| HSPA5 | heat shock 70kDa protein 5 (glucose-regulated protein, 78kDa) | -0.0237071 |
| EPC1 | enhancer of polycomb homolog 1 (Drosophila) | -0.0235236 |
| UBC | ubiquitin C | -0.0233614 |
| STAU1 | staufen double-stranded RNA binding protein 1 | -0.0233525 |
| RPL27A | ribosomal protein L27a | -0.0233326 |
| ITGA6 | integrin, alpha 6 | -0.0230384 |
| GPR107 | G protein-coupled receptor 107 | -0.022861 |
| PAIP2 | poly(A) binding protein interacting protein 2 | -0.0228432 |
| TAOK1 | TAO kinase 1 | -0.0227453 |
| PSMB7 | proteasome (prosome, macropain) subunit, beta type, 7 | -0.0226377 |
| PPP2CA | protein phosphatase 2, catalytic subunit, alpha isozyme | -0.0225345 |
| ABCF1 | ATP-binding cassette, sub-family F (GCN20), member 1 | -0.0223334 |
| SRSF11 | serine/arginine-rich splicing factor 11 | -0.02226 |
| RPL5 | ribosomal protein L5 | -0.022205 |
| YAP1 | Yes-associated protein 1 | -0.0221755 |
| HERC4 | HECT and RLD domain containing E3 ubiquitin protein ligase 4 | -0.0219674 |
| TRIP12 | thyroid hormone receptor interactor 12 | -0.0219373 |
| FANCI | Fanconi anemia, complementation group I | -0.0219293 |
| SSB | Sjogren syndrome antigen B (autoantigen La) | -0.0218748 |
| CALM2 | calmodulin 2 (phosphorylase kinase, delta) | -0.0218221 |
| RPL31 | ribosomal protein L31 | -0.0217412 |
| CLTC | clathrin, heavy chain (Hc) | -0.0216694 |
| IPO5 | importin 5 | -0.0215168 |
| PDS5B | PDS5 cohesin associated factor B | -0.0214451 |
| CENPF | centromere protein F, 350/400kDa | -0.0213859 |
| TAF7 | TAF7 RNA polymerase II, TATA box binding protein (TBP)-associated factor, 55kDa | -0.0213596 |
| MSANTD3 | Myb/SANT-like DNA-binding domain containing 3 | -0.0211681 |
| STRN3 | striatin, calmodulin binding protein 3 | -0.0210302 |
| MTPN | myotrophin | -0.0209023 |
| CCT5 | chaperonin containing TCP1, subunit 5 (epsilon) | -0.0208701 |
| MNAT1 | MNAT CDK-activating kinase assembly factor 1 | -0.0205239 |
| TOM1L1 | target of myb1 (chicken)-like 1 | -0.0204415 |
| HDAC2 | histone deacetylase 2 | -0.0203569 |
| FTL | ferritin, light polypeptide | -0.020242 |
| KRTAP11-1 | keratin associated protein 11-1 | -0.0202356 |
| PDGFA | platelet-derived growth factor alpha polypeptide | -0.0200237 |
| RPL34 | ribosomal protein L34 | -0.019713 |
| EIF2AK2 | eukaryotic translation initiation factor 2-alpha kinase 2 | -0.0195382 |
| SOD2 | superoxide dismutase 2, mitochondrial | -0.0194871 |
| ARPC2 | actin related protein 2/3 complex, subunit 2, 34kDa | -0.019437 |
| ATAD1 | ATPase family, AAA domain containing 1 | -0.0194315 |
| HNRNPA3 | heterogeneous nuclear ribonucleoprotein A3 | -0.0193782 |
| ZBTB35 | zinc finger and BTB domain containing 35 | -0.0193366 |
| RLIM | ring finger protein, LIM domain interacting | -0.0193282 |
| NSD2 | nuclear receptor binding SET domain protein 2 | -0.019319 |
| ANXA5 | annexin A5 | -0.0192862 |
| SPRED2 | sprouty-related, EVH1 domain containing 2 | -0.019268 |
