| Dataset | Tahoe Therapeutics Tahoe 100M Perturbation Atlas |
| Category | transcriptomics |
| Type | cell type |
| Description | Esmolol (hydrochloride) perturbation in SW48 cell line (Tahoe Therapeutics) |
| Similar Terms | |
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200 genes differentially expressed following the Esmolol (hydrochloride)_SW48 drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| SLC2A1 | solute carrier family 2 (facilitated glucose transporter), member 1 | 0.168138 |
| EGR1 | early growth response 1 | 0.141444 |
| HSP90AA1 | heat shock protein 90kDa alpha (cytosolic), class A member 1 | 0.105813 |
| EGFR | epidermal growth factor receptor | 0.100817 |
| HSPA8 | heat shock 70kDa protein 8 | 0.0952249 |
| ATXN1 | ataxin 1 | 0.0867507 |
| ACTG1 | actin gamma 1 | 0.0862622 |
| RCOR1 | REST corepressor 1 | 0.0834915 |
| AREG | amphiregulin | 0.077166 |
| LAMA4 | laminin, alpha 4 | 0.0749161 |
| RPL3 | ribosomal protein L3 | 0.0712867 |
| FHL2 | four and a half LIM domains 2 | 0.0702921 |
| RPS2 | ribosomal protein S2 | 0.0693155 |
| PHLDA1 | pleckstrin homology-like domain, family A, member 1 | 0.0633202 |
| FAT1 | FAT atypical cadherin 1 | 0.061418 |
| RPS6 | ribosomal protein S6 | 0.0602897 |
| SRRM2 | serine/arginine repetitive matrix 2 | 0.0594424 |
| MPRIP | myosin phosphatase Rho interacting protein | 0.0552054 |
| CCSER1 | coiled-coil serine-rich protein 1 | 0.0548967 |
| EEF2 | eukaryotic translation elongation factor 2 | 0.0526093 |
| NR4A1 | nuclear receptor subfamily 4, group A, member 1 | 0.0520973 |
| P4HB | prolyl 4-hydroxylase, beta polypeptide | 0.0500141 |
| NCEH1 | neutral cholesterol ester hydrolase 1 | 0.0498879 |
| ITGA2 | integrin, alpha 2 (CD49B, alpha 2 subunit of VLA-2 receptor) | 0.0492187 |
| GAPDH | glyceraldehyde-3-phosphate dehydrogenase | 0.048972 |
| SEPTIN9 | septin 9 | 0.0485487 |
| NR4A2 | nuclear receptor subfamily 4, group A, member 2 | 0.0457445 |
| SGMS2 | sphingomyelin synthase 2 | 0.0452835 |
| MACF1 | microtubule-actin crosslinking factor 1 | 0.0451273 |
| YAP1 | Yes-associated protein 1 | 0.0449428 |
| ZSWIM6 | zinc finger, SWIM-type containing 6 | 0.0445101 |
| CPOX | coproporphyrinogen oxidase | 0.0443497 |
| NTSR1 | neurotensin receptor 1 (high affinity) | 0.0438523 |
| SMAD3 | SMAD family member 3 | 0.0435631 |
| CTSB | cathepsin B | 0.0434439 |
| CLIP2 | CAP-GLY domain containing linker protein 2 | 0.0427373 |
| ZFP36L1 | ZFP36 ring finger protein-like 1 | 0.0422913 |
| SYNE2 | spectrin repeat containing, nuclear envelope 2 | 0.0422108 |
| HMGA2 | high mobility group AT-hook 2 | 0.0421335 |
| OSBPL10 | oxysterol binding protein-like 10 | 0.0417253 |
| MGAT5 | mannosyl (alpha-1,6-)-glycoprotein beta-1,6-N-acetyl-glucosaminyltransferase | 0.0414921 |
| AKAP13 | A kinase (PRKA) anchor protein 13 | 0.0413508 |
| LOC112694756 | uncharaterized LOC112694756 | 0.0410792 |
| POTEF | POTE ankyrin domain family, member F | 0.0409871 |
| ACTN4 | actinin, alpha 4 | 0.0408363 |
| EZR | ezrin | 0.0407515 |
| EPHA2 | EPH receptor A2 | 0.0406064 |
| SGPP2 | sphingosine-1-phosphate phosphatase 2 | 0.0405615 |
| DOCK5 | dedicator of cytokinesis 5 | 0.0404776 |
| NUP50 | nucleoporin 50kDa | 0.0399853 |
| VMP1 | vacuole membrane protein 1 | 0.0399662 |
| GBE1 | glucan (1,4-alpha-), branching enzyme 1 | 0.03879 |
| SIPA1L1 | signal-induced proliferation-associated 1 like 1 | 0.0387489 |
| RPS12 | ribosomal protein S12 | 0.0386902 |
| ZHX2 | zinc fingers and homeoboxes 2 | 0.0384564 |
| EFNB2 | ephrin-B2 | 0.0381117 |
| POLR2A | polymerase (RNA) II (DNA directed) polypeptide A, 220kDa | 0.0380477 |
| HIVEP2 | human immunodeficiency virus type I enhancer binding protein 2 | 0.0379553 |
| BRD2 | bromodomain containing 2 | 0.037075 |
| RABGEF1 | RAB guanine nucleotide exchange factor (GEF) 1 | 0.0370691 |
| ZNRF3 | zinc and ring finger 3 | 0.0369745 |
| BCL2L1 | BCL2-like 1 | 0.0355312 |
| FLNA | filamin A, alpha | 0.0353272 |
| NAALADL2 | N-acetylated alpha-linked acidic dipeptidase-like 2 | 0.0349894 |
| MIDEAS | mitotic deacetylase associated SANT domain protein | 0.0349719 |
| APLP2 | amyloid beta (A4) precursor-like protein 2 | 0.0347623 |
| EEF1A1 | eukaryotic translation elongation factor 1 alpha 1 | 0.0346595 |
| SLC12A2 | solute carrier family 12 (sodium/potassium/chloride transporter), member 2 | 0.0344548 |
| SORL1 | sortilin-related receptor, L(DLR class) A repeats containing | 0.0344483 |
| EIF4B | eukaryotic translation initiation factor 4B | 0.0339262 |
| HILPDA | hypoxia inducible lipid droplet-associated | 0.0338965 |
| MCL1 | myeloid cell leukemia 1 | 0.0335265 |
| PABPC1 | poly(A) binding protein, cytoplasmic 1 | 0.0330052 |
| MYH9 | myosin, heavy chain 9, non-muscle | 0.0329568 |
| RPS8 | ribosomal protein S8 | 0.032892 |
| VCL | vinculin | 0.032741 |
| RAD51B | RAD51 paralog B | 0.032664 |
| KITLG | KIT ligand | 0.0325689 |
| LOC102724023 | ES1 protein homolog, mitochondrial | 0.0324838 |
| TGFBR2 | transforming growth factor, beta receptor II (70/80kDa) | 0.0320551 |
| HSP90AB1 | heat shock protein 90kDa alpha (cytosolic), class B member 1 | 0.031687 |
| GATAD2A | GATA zinc finger domain containing 2A | 0.0316526 |
| ANXA2 | annexin A2 | 0.0314359 |
| DSCAM | Down syndrome cell adhesion molecule | 0.0313743 |
| SEMA3B | sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3B | 0.0307329 |
| AXIN2 | axin 2 | 0.0306277 |
| TNS3 | tensin 3 | 0.030439 |
| FOS | FBJ murine osteosarcoma viral oncogene homolog | 0.0301138 |
| BIRC3 | baculoviral IAP repeat containing 3 | 0.0292473 |
| FAM120A | family with sequence similarity 120A | 0.0289595 |
| PCBP2 | poly(rC) binding protein 2 | 0.0288429 |
| SAMD4A | sterile alpha motif domain containing 4A | 0.0282912 |
| TSC22D2 | TSC22 domain family, member 2 | 0.0279343 |
| ANKRD17 | ankyrin repeat domain 17 | 0.0277969 |
| ARIH1 | ariadne RBR E3 ubiquitin protein ligase 1 | 0.0275742 |
| MPP2 | membrane protein, palmitoylated 2 (MAGUK p55 subfamily member 2) | 0.0268425 |
| FTH1 | ferritin, heavy polypeptide 1 | 0.0266457 |
| NR4A3 | nuclear receptor subfamily 4, group A, member 3 | 0.0266163 |
| RPL27 | ribosomal protein L27 | 0.0266084 |
| SPATA13 | spermatogenesis associated 13 | 0.0263351 |
| Symbol | Name | Standardized Value |
|---|---|---|
| CD55 | CD55 molecule, decay accelerating factor for complement (Cromer blood group) | -0.141457 |
| TMSB10 | thymosin beta 10 | -0.133931 |
| HSPA5 | heat shock 70kDa protein 5 (glucose-regulated protein, 78kDa) | -0.113122 |
| FERMT1 | fermitin family member 1 | -0.112645 |
| PTMA | prothymosin, alpha | -0.111182 |
| RPS24 | ribosomal protein S24 | -0.0992773 |
| CD36 | CD36 molecule (thrombospondin receptor) | -0.0767908 |
| SERINC5 | serine incorporator 5 | -0.06805 |
| HDAC2 | histone deacetylase 2 | -0.0633634 |
| OXR1 | oxidation resistance 1 | -0.0569363 |
| TXNRD1 | thioredoxin reductase 1 | -0.0508375 |
| LMO7 | LIM domain 7 | -0.0503803 |
| RPL32 | ribosomal protein L32 | -0.0485136 |
| RPLP1 | ribosomal protein, large, P1 | -0.0463138 |
| NEK7 | NIMA-related kinase 7 | -0.0422026 |
| SCD | stearoyl-CoA desaturase (delta-9-desaturase) | -0.0413111 |
| MTAP | methylthioadenosine phosphorylase | -0.0408335 |
| RPL35A | ribosomal protein L35a | -0.0402569 |
| AOPEP | aminopeptidase O (putative) | -0.039531 |
| LRP8 | low density lipoprotein receptor-related protein 8, apolipoprotein e receptor | -0.0389506 |
| IER3 | immediate early response 3 | -0.0387576 |
| UBE3C | ubiquitin protein ligase E3C | -0.0386144 |
| CLTC | clathrin, heavy chain (Hc) | -0.0383232 |
| THOC2 | THO complex 2 | -0.0371176 |
| MARK3 | MAP/microtubule affinity-regulating kinase 3 | -0.0346288 |
| HPGD | hydroxyprostaglandin dehydrogenase 15-(NAD) | -0.033461 |
| HNRNPH1 | heterogeneous nuclear ribonucleoprotein H1 (H) | -0.0333844 |
| OSBPL3 | oxysterol binding protein-like 3 | -0.0329405 |
| NPEPPS | aminopeptidase puromycin sensitive | -0.0329114 |
| GOLGA4 | golgin A4 | -0.0327301 |
| BIRC6 | baculoviral IAP repeat containing 6 | -0.032485 |
| NEMF | nuclear export mediator factor | -0.0322996 |
| CALM2 | calmodulin 2 (phosphorylase kinase, delta) | -0.0315223 |
| PALS2 | protein associated with LIN7 2, MAGUK p55 family member | -0.031442 |
| PAN3 | PAN3 poly(A) specific ribonuclease subunit | -0.0312439 |
| HNRNPU | heterogeneous nuclear ribonucleoprotein U (scaffold attachment factor A) | -0.0304198 |
| KLF5 | Kruppel-like factor 5 (intestinal) | -0.0300243 |
| RBM25 | RNA binding motif protein 25 | -0.0296049 |
| ANAPC5 | anaphase promoting complex subunit 5 | -0.0295474 |
| FRAS1 | Fraser extracellular matrix complex subunit 1 | -0.028526 |
| MARCHF6 | membrane associated ring-CH-type finger 6 | -0.0284331 |
| DSG2 | desmoglein 2 | -0.0282711 |
| CCND1 | cyclin D1 | -0.0280905 |
| AVL9 | AVL9 homolog (S. cerevisiase) | -0.0279853 |
| ANLN | anillin, actin binding protein | -0.0277251 |
| MATR3 | matrin 3 | -0.0274753 |
| KRT18 | keratin 18, type I | -0.0268496 |
| HSP90B1 | heat shock protein 90kDa beta (Grp94), member 1 | -0.0265327 |
| TOMM20 | translocase of outer mitochondrial membrane 20 homolog (yeast) | -0.0261318 |
| RPL31 | ribosomal protein L31 | -0.0259302 |
| KLF3 | Kruppel-like factor 3 (basic) | -0.0257777 |
| RPL34 | ribosomal protein L34 | -0.0253122 |
| TBL1XR1 | transducin (beta)-like 1 X-linked receptor 1 | -0.0248479 |
| HIBADH | 3-hydroxyisobutyrate dehydrogenase | -0.024445 |
| LMAN1 | lectin, mannose-binding, 1 | -0.0242726 |
| NAP1L1 | nucleosome assembly protein 1-like 1 | -0.0238879 |
| PERP | PERP, TP53 apoptosis effector | -0.0237228 |
| RSL1D1 | ribosomal L1 domain containing 1 | -0.0233835 |
| CLASP2 | cytoplasmic linker associated protein 2 | -0.023284 |
| TMOD3 | tropomodulin 3 (ubiquitous) | -0.0228707 |
| RPL4 | ribosomal protein L4 | -0.0227517 |
| RRBP1 | ribosome binding protein 1 | -0.0225822 |
| IPO5 | importin 5 | -0.0225561 |
| CTDSPL | CTD (carboxy-terminal domain, RNA polymerase II, polypeptide A) small phosphatase-like | -0.0222739 |
| LAMC2 | laminin, gamma 2 | -0.0220523 |
| ANXA1 | annexin A1 | -0.0219325 |
| SRGAP1 | SLIT-ROBO Rho GTPase activating protein 1 | -0.0218777 |
| TKT | transketolase | -0.0218547 |
| SERPINB1 | serpin peptidase inhibitor, clade B (ovalbumin), member 1 | -0.0217132 |
| ATXN10 | ataxin 10 | -0.0215402 |
| COG5 | component of oligomeric golgi complex 5 | -0.0212372 |
| KRT8 | keratin 8, type II | -0.0209768 |
| ARF1 | ADP-ribosylation factor 1 | -0.0209285 |
| UBE2K | ubiquitin-conjugating enzyme E2K | -0.0208457 |
| VDAC1 | voltage-dependent anion channel 1 | -0.0208154 |
| CCT4 | chaperonin containing TCP1, subunit 4 (delta) | -0.0206992 |
| LRPPRC | leucine-rich pentatricopeptide repeat containing | -0.020689 |
| TNPO1 | transportin 1 | -0.0205591 |
| HSD17B12 | hydroxysteroid (17-beta) dehydrogenase 12 | -0.0204632 |
| PTPN11 | protein tyrosine phosphatase, non-receptor type 11 | -0.0204066 |
| COPB2 | coatomer protein complex, subunit beta 2 (beta prime) | -0.0203983 |
| DNAJC2 | DnaJ (Hsp40) homolog, subfamily C, member 2 | -0.0203659 |
| SLC25A36 | solute carrier family 25 (pyrimidine nucleotide carrier), member 36 | -0.020365 |
| PGK1 | phosphoglycerate kinase 1 | -0.0202194 |
| EIF3E | eukaryotic translation initiation factor 3, subunit E | -0.0202057 |
| NIPSNAP2 | nipsnap homolog 2 | -0.0201699 |
| GARS1 | glycyl-tRNA synthetase 1 | -0.0200718 |
| KPNB1 | karyopherin (importin) beta 1 | -0.0199239 |
| FAM3C | family with sequence similarity 3, member C | -0.0199081 |
| TDRD3 | tudor domain containing 3 | -0.0197619 |
| NFXL1 | nuclear transcription factor, X-box binding-like 1 | -0.0196713 |
| KDM3A | lysine (K)-specific demethylase 3A | -0.0192173 |
| GTF2I | general transcription factor IIi | -0.0191824 |
| EIF1 | eukaryotic translation initiation factor 1 | -0.0190646 |
| TFRC | transferrin receptor | -0.0189335 |
| ST13 | suppression of tumorigenicity 13 (colon carcinoma) (Hsp70 interacting protein) | -0.0189117 |
| PPFIBP1 | PTPRF interacting protein, binding protein 1 (liprin beta 1) | -0.0188904 |
| MYO6 | myosin VI | -0.0187832 |
| OGA | O-GlcNAcase | -0.0187719 |
| ARPP19 | cAMP-regulated phosphoprotein, 19kDa | -0.0186323 |
