| Dataset | Tahoe Therapeutics Tahoe 100M Perturbation Atlas |
| Category | transcriptomics |
| Type | cell type |
| Description | Esmolol (hydrochloride) perturbation in SW480 cell line (Tahoe Therapeutics) |
| Similar Terms | |
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200 genes differentially expressed following the Esmolol (hydrochloride)_SW480 drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| NKD1 | naked cuticle homolog 1 (Drosophila) | 0.424168 |
| MAML2 | mastermind-like 2 (Drosophila) | 0.113143 |
| NAV2 | neuron navigator 2 | 0.105583 |
| SLC2A1 | solute carrier family 2 (facilitated glucose transporter), member 1 | 0.102544 |
| TNS3 | tensin 3 | 0.0857951 |
| RUNX1 | runt-related transcription factor 1 | 0.0852717 |
| GAPDH | glyceraldehyde-3-phosphate dehydrogenase | 0.0815146 |
| PPFIBP1 | PTPRF interacting protein, binding protein 1 (liprin beta 1) | 0.0808661 |
| PDE4D | phosphodiesterase 4D, cAMP-specific | 0.0781654 |
| ACTN4 | actinin, alpha 4 | 0.077723 |
| CDH13 | cadherin 13 | 0.0756257 |
| NFAT5 | nuclear factor of activated T-cells 5, tonicity-responsive | 0.0754085 |
| SPATA13 | spermatogenesis associated 13 | 0.0742534 |
| ENO1 | enolase 1, (alpha) | 0.0738274 |
| ROBO2 | roundabout, axon guidance receptor, homolog 2 (Drosophila) | 0.0734369 |
| SYT1 | synaptotagmin I | 0.0716605 |
| HSP90AA1 | heat shock protein 90kDa alpha (cytosolic), class A member 1 | 0.0709173 |
| ACTG1 | actin gamma 1 | 0.0704784 |
| LOC102724023 | ES1 protein homolog, mitochondrial | 0.0679301 |
| WWOX | WW domain containing oxidoreductase | 0.0665991 |
| SNTB1 | syntrophin, beta 1 (dystrophin-associated protein A1, 59kDa, basic component 1) | 0.0664266 |
| IMMP2L | IMP2 inner mitochondrial membrane peptidase-like (S. cerevisiae) | 0.0650819 |
| KRT18 | keratin 18, type I | 0.0643844 |
| BCL2L1 | BCL2-like 1 | 0.0626694 |
| MYCBP2 | MYC binding protein 2, E3 ubiquitin protein ligase | 0.0617205 |
| RAD51B | RAD51 paralog B | 0.0606048 |
| PABPC1 | poly(A) binding protein, cytoplasmic 1 | 0.0600446 |
| PTPN14 | protein tyrosine phosphatase, non-receptor type 14 | 0.0573453 |
| EGR1 | early growth response 1 | 0.0568584 |
| RPS6 | ribosomal protein S6 | 0.0567176 |
| MYH9 | myosin, heavy chain 9, non-muscle | 0.0553042 |
| VCL | vinculin | 0.0551067 |
| HDAC4 | histone deacetylase 4 | 0.0543238 |
| DST | dystonin | 0.0536797 |
| ITPR2 | inositol 1,4,5-trisphosphate receptor, type 2 | 0.0507664 |
| POLR2A | polymerase (RNA) II (DNA directed) polypeptide A, 220kDa | 0.0506225 |
| FYN | FYN proto-oncogene, Src family tyrosine kinase | 0.0504649 |
| SLC1A5 | solute carrier family 1 (neutral amino acid transporter), member 5 | 0.0492461 |
| EZR | ezrin | 0.0489031 |
| ATXN1 | ataxin 1 | 0.0485228 |
| PGK1 | phosphoglycerate kinase 1 | 0.0478687 |
| MSI2 | musashi RNA-binding protein 2 | 0.0477245 |
| CDK6 | cyclin-dependent kinase 6 | 0.0474321 |
| ROBO1 | roundabout, axon guidance receptor, homolog 1 (Drosophila) | 0.0470148 |
| ACTN1 | actinin, alpha 1 | 0.0462391 |
| KRT8 | keratin 8, type II | 0.0460507 |
| AOPEP | aminopeptidase O (putative) | 0.0459595 |
| CEMIP | cell migration inducing protein, hyaluronan binding | 0.0451798 |
| MTCL1 | microtubule crosslinking factor 1 | 0.0445983 |
| SEMA3A | sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3A | 0.0444574 |
| SEPTIN9 | septin 9 | 0.0443425 |
| ETNK1 | ethanolamine kinase 1 | 0.0443356 |
| DSPP | dentin sialophosphoprotein | 0.0439698 |
| YAP1 | Yes-associated protein 1 | 0.0434522 |
| CTDSPL | CTD (carboxy-terminal domain, RNA polymerase II, polypeptide A) small phosphatase-like | 0.0433217 |
| HNRNPA2B1 | heterogeneous nuclear ribonucleoprotein A2/B1 | 0.0431276 |
| POTEF | POTE ankyrin domain family, member F | 0.0430655 |
| OXR1 | oxidation resistance 1 | 0.042983 |
| SKAP1 | src kinase associated phosphoprotein 1 | 0.0427193 |
| CTNNB1 | catenin (cadherin-associated protein), beta 1, 88kDa | 0.0425388 |
| MGAT5 | mannosyl (alpha-1,6-)-glycoprotein beta-1,6-N-acetyl-glucosaminyltransferase | 0.042128 |
| LDHA | lactate dehydrogenase A | 0.0418701 |
| CEMIP2 | cell migration inducing hyaluronidase 2 | 0.0415734 |
| YWHAE | tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, epsilon | 0.0414388 |
| NEBL | nebulette | 0.0413652 |
| SMYD3 | SET and MYND domain containing 3 | 0.0408301 |
| ANKRD17 | ankyrin repeat domain 17 | 0.0402396 |
| PROX1 | prospero homeobox 1 | 0.0401317 |
| PRAG1 | PEAK1 related, kinase-activating pseudokinase 1 | 0.040068 |
| RERE | arginine-glutamic acid dipeptide (RE) repeats | 0.0397607 |
| PTPRN2 | protein tyrosine phosphatase, receptor type, N polypeptide 2 | 0.039367 |
| NCEH1 | neutral cholesterol ester hydrolase 1 | 0.0392787 |
| EEF2 | eukaryotic translation elongation factor 2 | 0.0392704 |
| ANXA2 | annexin A2 | 0.0391349 |
| HSPD1 | heat shock 60kDa protein 1 (chaperonin) | 0.0389659 |
| VMP1 | vacuole membrane protein 1 | 0.0388347 |
| EXOC4 | exocyst complex component 4 | 0.0386024 |
| CD46 | CD46 molecule, complement regulatory protein | 0.0384868 |
| HNRNPA1 | heterogeneous nuclear ribonucleoprotein A1 | 0.0384153 |
| ZNRF3 | zinc and ring finger 3 | 0.0383269 |
| GMDS | GDP-mannose 4,6-dehydratase | 0.038187 |
| APP | amyloid beta (A4) precursor protein | 0.038012 |
| ADGRL2 | adhesion G protein-coupled receptor L2 | 0.0374585 |
| ARGLU1 | arginine and glutamate rich 1 | 0.0372236 |
| LPP | LIM domain containing preferred translocation partner in lipoma | 0.0370218 |
| DCBLD2 | discoidin, CUB and LCCL domain containing 2 | 0.0365921 |
| KIZ | kizuna centrosomal protein | 0.0362225 |
| CDKAL1 | CDK5 regulatory subunit associated protein 1-like 1 | 0.0346296 |
| SRRM2 | serine/arginine repetitive matrix 2 | 0.0343452 |
| PCBP2 | poly(rC) binding protein 2 | 0.0341143 |
| SLC38A2 | solute carrier family 38, member 2 | 0.0336845 |
| MACF1 | microtubule-actin crosslinking factor 1 | 0.0335796 |
| H1-0 | H1.0 linker histone | 0.0332944 |
| IGF1R | insulin-like growth factor 1 receptor | 0.0332825 |
| HUWE1 | HECT, UBA and WWE domain containing 1, E3 ubiquitin protein ligase | 0.0332127 |
| ADNP | activity-dependent neuroprotector homeobox | 0.0330989 |
| APBB2 | amyloid beta (A4) precursor protein-binding, family B, member 2 | 0.0327839 |
| BPTF | bromodomain PHD finger transcription factor | 0.0327364 |
| SMURF2 | SMAD specific E3 ubiquitin protein ligase 2 | 0.0324041 |
| TMEM163 | transmembrane protein 163 | 0.0320952 |
| Symbol | Name | Standardized Value |
|---|---|---|
| SLC2A3 | solute carrier family 2 (facilitated glucose transporter), member 3 | -0.0350134 |
| AKAP12 | A kinase (PRKA) anchor protein 12 | -0.0258803 |
| NDRG1 | N-myc downstream regulated 1 | -0.0217254 |
| ESYT2 | extended synaptotagmin-like protein 2 | -0.0190944 |
| HSPA5 | heat shock 70kDa protein 5 (glucose-regulated protein, 78kDa) | -0.0170545 |
| KDM3A | lysine (K)-specific demethylase 3A | -0.0163877 |
| RPS24 | ribosomal protein S24 | -0.0144402 |
| GOLGA4 | golgin A4 | -0.0131646 |
| SLC5A3 | solute carrier family 5 (sodium/myo-inositol cotransporter), member 3 | -0.0129361 |
| ERO1A | endoplasmic reticulum oxidoreductase 1 alpha | -0.0119098 |
| HSPH1 | heat shock 105kDa/110kDa protein 1 | -0.011326 |
| RIOK3 | RIO kinase 3 | -0.0111787 |
| MORF4L2 | mortality factor 4 like 2 | -0.011012 |
| COPB2 | coatomer protein complex, subunit beta 2 (beta prime) | -0.0100274 |
| ITGA2 | integrin, alpha 2 (CD49B, alpha 2 subunit of VLA-2 receptor) | -0.0097911 |
| ARRDC3 | arrestin domain containing 3 | -0.00949701 |
| PNRC1 | proline-rich nuclear receptor coactivator 1 | -0.00915322 |
| EMP1 | epithelial membrane protein 1 | -0.00898615 |
| INSIG2 | insulin induced gene 2 | -0.00889518 |
| SPAG9 | sperm associated antigen 9 | -0.00881324 |
| GOLT1B | golgi transport 1B | -0.00870832 |
| ABHD3 | abhydrolase domain containing 3 | -0.00860511 |
| RNMT | RNA (guanine-7-) methyltransferase | -0.00849418 |
| NPM1 | nucleophosmin (nucleolar phosphoprotein B23, numatrin) | -0.00839729 |
| NAMPT | nicotinamide phosphoribosyltransferase | -0.00813989 |
| EIF1 | eukaryotic translation initiation factor 1 | -0.00813738 |
| AHNAK | AHNAK nucleoprotein | -0.00813408 |
| RPL31 | ribosomal protein L31 | -0.0078539 |
| RPL38 | ribosomal protein L38 | -0.00744222 |
| CALM2 | calmodulin 2 (phosphorylase kinase, delta) | -0.0074268 |
| H1-4 | H1.4 linker histone, cluster member | -0.00729856 |
| OGA | O-GlcNAcase | -0.00729429 |
| ANO1 | anoctamin 1, calcium activated chloride channel | -0.00727601 |
| PJA2 | praja ring finger 2, E3 ubiquitin protein ligase | -0.00720229 |
| RNF168 | ring finger protein 168, E3 ubiquitin protein ligase | -0.0071952 |
| TMCO3 | transmembrane and coiled-coil domains 3 | -0.00711525 |
| SERINC3 | serine incorporator 3 | -0.00701785 |
| FTL | ferritin, light polypeptide | -0.00697304 |
| RECQL | RecQ helicase-like | -0.00691193 |
| TBC1D4 | TBC1 domain family, member 4 | -0.00688155 |
| MAP3K2 | mitogen-activated protein kinase kinase kinase 2 | -0.00685886 |
| EIF4A2 | eukaryotic translation initiation factor 4A2 | -0.0066044 |
| TNFRSF10D | tumor necrosis factor receptor superfamily, member 10d, decoy with truncated death domain | -0.00652341 |
| GPRC5A | G protein-coupled receptor, class C, group 5, member A | -0.00651132 |
| FYTTD1 | forty-two-three domain containing 1 | -0.00649749 |
| GULP1 | GULP, engulfment adaptor PTB domain containing 1 | -0.00647995 |
| DDX3X | DEAD (Asp-Glu-Ala-Asp) box helicase 3, X-linked | -0.00647487 |
| ANLN | anillin, actin binding protein | -0.00633884 |
| MARK3 | MAP/microtubule affinity-regulating kinase 3 | -0.00633855 |
| DDIT4 | DNA-damage-inducible transcript 4 | -0.00630823 |
| SLC25A36 | solute carrier family 25 (pyrimidine nucleotide carrier), member 36 | -0.0061619 |
| IGF2 | insulin-like growth factor 2 | -0.00606477 |
| GMCL1 | germ cell-less, spermatogenesis associated 1 | -0.00590232 |
| RAB5A | RAB5A, member RAS oncogene family | -0.00589752 |
| ERRFI1 | ERBB receptor feedback inhibitor 1 | -0.00585274 |
| FNBP1 | formin binding protein 1 | -0.00580806 |
| TAC4 | tachykinin 4 (hemokinin) | -0.00574616 |
| SUCO | SUN domain containing ossification factor | -0.00568117 |
| COG5 | component of oligomeric golgi complex 5 | -0.00567687 |
| MXI1 | MAX interactor 1, dimerization protein | -0.00565654 |
| SLC31A1 | solute carrier family 31 (copper transporter), member 1 | -0.00562949 |
| SERINC1 | serine incorporator 1 | -0.00556999 |
| RYBP | RING1 and YY1 binding protein | -0.00550922 |
| UPP1 | uridine phosphorylase 1 | -0.00550447 |
| GAN | gigaxonin | -0.0054864 |
| ZNF706 | zinc finger protein 706 | -0.0054753 |
| PLAUR | plasminogen activator, urokinase receptor | -0.00545415 |
| GTF2B | general transcription factor IIB | -0.00544947 |
| RPL6 | ribosomal protein L6 | -0.00536121 |
| TXNRD1 | thioredoxin reductase 1 | -0.00535167 |
| KLF5 | Kruppel-like factor 5 (intestinal) | -0.00530462 |
| RPL14 | ribosomal protein L14 | -0.00529888 |
| SELENOK | selenoprotein K | -0.00528842 |
| CD44 | CD44 molecule (Indian blood group) | -0.00519349 |
| TMSB10 | thymosin beta 10 | -0.00518928 |
| PARK7 | parkinson protein 7 | -0.00516286 |
| ZNF654 | zinc finger protein 654 | -0.00514797 |
| UBXN7 | UBX domain protein 7 | -0.00512912 |
| CACNB4 | calcium channel, voltage-dependent, beta 4 subunit | -0.00511077 |
| RPL41 | ribosomal protein L41 | -0.00507394 |
| P4HA1 | prolyl 4-hydroxylase, alpha polypeptide I | -0.00507136 |
| SAMD8 | sterile alpha motif domain containing 8 | -0.00503261 |
| GABARAPL2 | GABA(A) receptor-associated protein-like 2 | -0.00502339 |
| TAF15 | TAF15 RNA polymerase II, TATA box binding protein (TBP)-associated factor, 68kDa | -0.004998 |
| AP3S1 | adaptor-related protein complex 3, sigma 1 subunit | -0.00499615 |
| SPDYA | speedy/RINGO cell cycle regulator family member A | -0.00497067 |
| SPTY2D1 | SPT2, Suppressor of Ty, domain containing 1 (S. cerevisiae) | -0.00492412 |
| DNAJC3 | DnaJ (Hsp40) homolog, subfamily C, member 3 | -0.00484434 |
| ACBD3 | acyl-CoA binding domain containing 3 | -0.00476805 |
| OPTN | optineurin | -0.00466056 |
| FAM199X | family with sequence similarity 199, X-linked | -0.00466004 |
| FUT11 | fucosyltransferase 11 (alpha (1,3) fucosyltransferase) | -0.00458544 |
| HMGCS1 | 3-hydroxy-3-methylglutaryl-CoA synthase 1 (soluble) | -0.00458101 |
| GOLPH3L | golgi phosphoprotein 3-like | -0.00456894 |
| ATP1B3 | ATPase, Na+/K+ transporting, beta 3 polypeptide | -0.00455156 |
| DNAJA1 | DnaJ (Hsp40) homolog, subfamily A, member 1 | -0.00453758 |
| ARHGEF4 | Rho guanine nucleotide exchange factor (GEF) 4 | -0.00445035 |
| BNIP3L | BCL2/adenovirus E1B 19kDa interacting protein 3-like | -0.00444575 |
| WASF2 | WAS protein family, member 2 | -0.00439593 |
| ZNF92 | zinc finger protein 92 | -0.0043863 |
