Ethambutol Gene Set

Dataset CTD Gene-Chemical Interactions
Category physical interactions
Type chemical
Description An ethylenediamine derivative that is ethane-1,2-diamine in which one hydrogen attached to each of the nitrogens is sutstituted by a 1-hydroxybutan-2-yl group (S,S-configuration). It is a bacteriostatic antimycobacterial drug, effective against Mycobacterium tuberculosis and some other mycobacteria. It is used (as the dihydrochloride salt) in combination with other antituberculous drugs in the treatment of pulmonary and extrapulmonary tuberculosis; resistant strains of M. tuberculosis are readily produced if ethambutol is used alone. (Chemical Entities of Biological Interest Ontology, CHEBI_4877)
External Link http://ctdbase.org/detail.go?type=chem&acc=D004977
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Genes

10 genes/proteins interacting with the chemical Ethambutol from the curated CTD Gene-Chemical Interactions dataset.

Symbol Name
CCL5 chemokine (C-C motif) ligand 5
CTSD cathepsin D
CYP1A2 cytochrome P450, family 1, subfamily A, polypeptide 2
CYP2C19 cytochrome P450, family 2, subfamily C, polypeptide 19
CYP2D6 cytochrome P450, family 2, subfamily D, polypeptide 6
CYP2E1 cytochrome P450, family 2, subfamily E, polypeptide 1
IL10 interleukin 10
IL6 interleukin 6
LAMP2 lysosomal-associated membrane protein 2
LEP leptin