Etodolac Gene Set

Dataset CTD Gene-Chemical Interactions
Category physical interactions
Type chemical
Description A monocarboxylic acid that is acetic acid in which one of the methyl hydrogens is substituted by a 1,8-diethyl-1,3,4,9-tetrahydropyrano[3,4-b]indol-1-yl moiety. A preferential inhibitor of cyclo-oxygenase 2 and non-steroidal anti-inflammatory, it is used for the treatment of rheumatoid arthritis and osteoarthritis, and for the alleviation of postoperative pain. Administered as the racemate, only the (S)-enantiomer is active. (Chemical Entities of Biological Interest Ontology, CHEBI_4909)
External Link http://ctdbase.org/detail.go?type=chem&acc=D017308
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Genes

19 genes/proteins interacting with the chemical Etodolac from the curated CTD Gene-Chemical Interactions dataset.

Symbol Name
BCL2 B-cell CLL/lymphoma 2
BIRC2 baculoviral IAP repeat containing 2
BIRC5 baculoviral IAP repeat containing 5
CASP3 caspase 3, apoptosis-related cysteine peptidase
CASP7 caspase 7, apoptosis-related cysteine peptidase
CASP9 caspase 9, apoptosis-related cysteine peptidase
CD44 CD44 molecule (Indian blood group)
CXCR4 chemokine (C-X-C motif) receptor 4
CYP1A2 cytochrome P450, family 1, subfamily A, polypeptide 2
ITGA4 integrin, alpha 4 (antigen CD49D, alpha 4 subunit of VLA-4 receptor)
ITGAL integrin, alpha L (antigen CD11A (p180), lymphocyte function-associated antigen 1; alpha polypeptide)
ITGB1 integrin, beta 1 (fibronectin receptor, beta polypeptide, antigen CD29 includes MDF2, MSK12)
PTGS1 prostaglandin-endoperoxide synthase 1 (prostaglandin G/H synthase and cyclooxygenase)
PTGS2 prostaglandin-endoperoxide synthase 2 (prostaglandin G/H synthase and cyclooxygenase)
RXRA retinoid X receptor, alpha
UGT1A10 UDP glucuronosyltransferase 1 family, polypeptide A10
UGT1A3 UDP glucuronosyltransferase 1 family, polypeptide A3
UGT1A9 UDP glucuronosyltransferase 1 family, polypeptide A9
UGT2B7 UDP glucuronosyltransferase 2 family, polypeptide B7