Etoposide Gene Set

Dataset CTD Gene-Chemical Interactions
Category physical interactions
Type chemical
Description A furonaphthodioxole that has formula C29H32O13. (Chemical Entities of Biological Interest Ontology, CHEBI_4911)
External Link http://ctdbase.org/detail.go?type=chem&acc=D005047
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Genes

303 genes/proteins interacting with the chemical Etoposide from the curated CTD Gene-Chemical Interactions dataset.

Symbol Name
ABCB1 ATP-binding cassette, sub-family B (MDR/TAP), member 1
ABCC1 ATP-binding cassette, sub-family C (CFTR/MRP), member 1
ABCC2 ATP-binding cassette, sub-family C (CFTR/MRP), member 2
ABCC3 ATP-binding cassette, sub-family C (CFTR/MRP), member 3
ACADM acyl-CoA dehydrogenase, C-4 to C-12 straight chain
ACSL3 acyl-CoA synthetase long-chain family member 3
AHCYL1 adenosylhomocysteinase-like 1
AKAP12 A kinase (PRKA) anchor protein 12
AKT1 v-akt murine thymoma viral oncogene homolog 1
ALAD aminolevulinate dehydratase
ALDH3A1 aldehyde dehydrogenase 3 family, member A1
ALDOC aldolase C, fructose-bisphosphate
ALPP alkaline phosphatase, placental
ALPPL2 alkaline phosphatase, placental-like 2
ANKRD28 ankyrin repeat domain 28
APEX1 APEX nuclease (multifunctional DNA repair enzyme) 1
APOBEC3C apolipoprotein B mRNA editing enzyme, catalytic polypeptide-like 3C
AR androgen receptor
AREG amphiregulin
ARL6IP5 ADP-ribosylation factor-like 6 interacting protein 5
ASAH1 N-acylsphingosine amidohydrolase (acid ceramidase) 1
ATF2 activating transcription factor 2
ATM ATM serine/threonine kinase
ATP1A1 ATPase, Na+/K+ transporting, alpha 1 polypeptide
ATP6V0A4 ATPase, H+ transporting, lysosomal V0 subunit a4
ATP7A ATPase, Cu++ transporting, alpha polypeptide
ATR ATR serine/threonine kinase
AVPI1 arginine vasopressin-induced 1
BACE2 beta-site APP-cleaving enzyme 2
BAG2 BCL2-associated athanogene 2
BAK1 BCL2-antagonist/killer 1
BAMBI BMP and activin membrane-bound inhibitor
BAX BCL2-associated X protein
BBC3 BCL2 binding component 3
BCL2 B-cell CLL/lymphoma 2
BCL2L1 BCL2-like 1
BID BH3 interacting domain death agonist
BIK BCL2-interacting killer (apoptosis-inducing)
BIN1 bridging integrator 1
BIN3 bridging integrator 3
BIRC2 baculoviral IAP repeat containing 2
BIRC3 baculoviral IAP repeat containing 3
BIRC5 baculoviral IAP repeat containing 5
BIRC7 baculoviral IAP repeat containing 7
BRCA1 breast cancer 1, early onset
C4ORF19 chromosome 4 open reading frame 19
C5ORF22 chromosome 5 open reading frame 22
C7ORF49 chromosome 7 open reading frame 49
CADPS2 Ca++-dependent secretion activator 2
CALCA calcitonin-related polypeptide alpha
CASP3 caspase 3, apoptosis-related cysteine peptidase
CASP7 caspase 7, apoptosis-related cysteine peptidase
CASP8 caspase 8, apoptosis-related cysteine peptidase
CASP9 caspase 9, apoptosis-related cysteine peptidase
CAT catalase
CCL3 chemokine (C-C motif) ligand 3
CCNA2 cyclin A2
CCNB1 cyclin B1
CD274 CD274 molecule
CD40LG CD40 ligand
CD44 CD44 molecule (Indian blood group)
CD55 CD55 molecule, decay accelerating factor for complement (Cromer blood group)
CD59 CD59 molecule, complement regulatory protein
CDK2 cyclin-dependent kinase 2
CDKN1A cyclin-dependent kinase inhibitor 1A (p21, Cip1)
CDKN1B cyclin-dependent kinase inhibitor 1B (p27, Kip1)
CEBPA CCAAT/enhancer binding protein (C/EBP), alpha
CFLAR CASP8 and FADD-like apoptosis regulator
CHEK1 checkpoint kinase 1
CHEK2 checkpoint kinase 2
CIAPIN1 cytokine induced apoptosis inhibitor 1
CKMT1B creatine kinase, mitochondrial 1B
COL15A1 collagen, type XV, alpha 1
COL9A3 collagen, type IX, alpha 3
CPS1 carbamoyl-phosphate synthase 1, mitochondrial
CREB1 cAMP responsive element binding protein 1
CREM cAMP responsive element modulator
CSGALNACT1 chondroitin sulfate N-acetylgalactosaminyltransferase 1
CST1 cystatin SN
CTH cystathionine gamma-lyase
CTNNB1 catenin (cadherin-associated protein), beta 1, 88kDa
CXCL12 chemokine (C-X-C motif) ligand 12
CXCL8 chemokine (C-X-C motif) ligand 8
CYCS cytochrome c, somatic
CYP3A4 cytochrome P450, family 3, subfamily A, polypeptide 4
CYP3A5 cytochrome P450, family 3, subfamily A, polypeptide 5
DAB2 Dab, mitogen-responsive phosphoprotein, homolog 2 (Drosophila)
DBN1 drebrin 1
DCT dopachrome tautomerase
DDIT4 DNA-damage-inducible transcript 4
DKK3 dickkopf WNT signaling pathway inhibitor 3
DMD dystrophin
DNMT1 DNA (cytosine-5-)-methyltransferase 1
DNMT3B DNA (cytosine-5-)-methyltransferase 3 beta
DPP7 dipeptidyl-peptidase 7
DUSP2 dual specificity phosphatase 2
DUSP4 dual specificity phosphatase 4
E2F1 E2F transcription factor 1
EGF epidermal growth factor
EGFL8 EGF-like-domain, multiple 8
EGFR epidermal growth factor receptor
EMP2 epithelial membrane protein 2
EN2 engrailed homeobox 2
EP300 E1A binding protein p300
EPB41L3 erythrocyte membrane protein band 4.1-like 3
EPO erythropoietin
ERBB2 erb-b2 receptor tyrosine kinase 2
ERBB3 erb-b2 receptor tyrosine kinase 3
ERVFRD-1 endogenous retrovirus group FRD, member 1
ESR2 estrogen receptor 2 (ER beta)
ESRP1 epithelial splicing regulatory protein 1
ETV6 ets variant 6
F2R coagulation factor II (thrombin) receptor
FAM129A family with sequence similarity 129, member A
FAM171A1 family with sequence similarity 171, member A1
FAM46A family with sequence similarity 46, member A
FAS Fas cell surface death receptor
FBL fibrillarin
FDFT1 farnesyl-diphosphate farnesyltransferase 1
FGF2 fibroblast growth factor 2 (basic)
FHL1 four and a half LIM domains 1
FOS FBJ murine osteosarcoma viral oncogene homolog
FOXF2 forkhead box F2
FOXO1 forkhead box O1
FOXO3 forkhead box O3
FUT8 fucosyltransferase 8 (alpha (1,6) fucosyltransferase)
FYN FYN proto-oncogene, Src family tyrosine kinase
GADD45A growth arrest and DNA-damage-inducible, alpha
GCLC glutamate-cysteine ligase, catalytic subunit
GCLM glutamate-cysteine ligase, modifier subunit
GDF15 growth differentiation factor 15
GJA1 gap junction protein, alpha 1, 43kDa
GPM6B glycoprotein M6B
GPR37 G protein-coupled receptor 37 (endothelin receptor type B-like)
GPSM2 G-protein signaling modulator 2
GSK3B glycogen synthase kinase 3 beta
GSTM1 glutathione S-transferase mu 1
GSTM4 glutathione S-transferase mu 4
GSTP1 glutathione S-transferase pi 1
GSTT2 glutathione S-transferase theta 2 (gene/pseudogene)
H2AFX H2A histone family, member X
HDAC4 histone deacetylase 4
HEPH hephaestin
HIPK2 homeodomain interacting protein kinase 2
HMG20B high mobility group 20B
HMGA2 high mobility group AT-hook 2
HOXA5 homeobox A5
HSPA2 heat shock 70kDa protein 2
HTATIP2 HIV-1 Tat interactive protein 2, 30kDa
HTR4 5-hydroxytryptamine (serotonin) receptor 4, G protein-coupled
IFITM1 interferon induced transmembrane protein 1
IGF1R insulin-like growth factor 1 receptor
IGFBP7 insulin-like growth factor binding protein 7
IKBKB inhibitor of kappa light polypeptide gene enhancer in B-cells, kinase beta
IL4 interleukin 4
IL6 interleukin 6
INSIG1 insulin induced gene 1
IRS2 insulin receptor substrate 2
ISG20 interferon stimulated exonuclease gene 20kDa
ITGB3 integrin, beta 3 (platelet glycoprotein IIIa, antigen CD61)
ITPR1 inositol 1,4,5-trisphosphate receptor, type 1
KCNAB2 potassium channel, voltage gated subfamily A regulatory beta subunit 2
KEAP1 kelch-like ECH-associated protein 1
KMT2A lysine (K)-specific methyltransferase 2A
KYNU kynureninase
LANCL1 LanC lantibiotic synthetase component C-like 1 (bacterial)
LCN2 lipocalin 2
LGALS3 lectin, galactoside-binding, soluble, 3
LIMCH1 LIM and calponin homology domains 1
LIPA lipase A, lysosomal acid, cholesterol esterase
LY6E lymphocyte antigen 6 complex, locus E
MACF1 microtubule-actin crosslinking factor 1
MAGEA12 melanoma antigen family A12
MAGEA6 melanoma antigen family A6
MAGEC1 melanoma antigen family C1
MAP7 microtubule-associated protein 7
MAPK1 mitogen-activated protein kinase 1
MAPK12 mitogen-activated protein kinase 12
MAPK3 mitogen-activated protein kinase 3
MAPKAPK2 mitogen-activated protein kinase-activated protein kinase 2
MATN2 matrilin 2
MBP myelin basic protein
MCL1 myeloid cell leukemia 1
MDFIC MyoD family inhibitor domain containing
MDM2 MDM2 proto-oncogene, E3 ubiquitin protein ligase
MLANA melan-A
MLLT11 myeloid/lymphoid or mixed-lineage leukemia (trithorax homolog, Drosophila); translocated to, 11
MMP1 matrix metallopeptidase 1
MOCOS molybdenum cofactor sulfurase
MPO myeloperoxidase
MTUS1 microtubule associated tumor suppressor 1
MXI1 MAX interactor 1, dimerization protein
MYC v-myc avian myelocytomatosis viral oncogene homolog
MYCN v-myc avian myelocytomatosis viral oncogene neuroblastoma derived homolog
NAP1L1 nucleosome assembly protein 1-like 1
NEDD9 neural precursor cell expressed, developmentally down-regulated 9
NFKBIA nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor, alpha
NMT2 N-myristoyltransferase 2
NQO1 NAD(P)H dehydrogenase, quinone 1
NR1I2 nuclear receptor subfamily 1, group I, member 2
NRIP1 nuclear receptor interacting protein 1
NUPR1 nuclear protein, transcriptional regulator, 1
OCA2 oculocutaneous albinism II
PARP1 poly (ADP-ribose) polymerase 1
PBK PDZ binding kinase
PDE4B phosphodiesterase 4B, cAMP-specific
PDGFC platelet derived growth factor C
PHGDH phosphoglycerate dehydrogenase
PIP5K1B phosphatidylinositol-4-phosphate 5-kinase, type I, beta
PLP1 proteolipid protein 1
PMEL premelanosome protein
PMP2 peripheral myelin protein 2
PMP22 peripheral myelin protein 22
POMZP3 POM121 and ZP3 fusion
PPM1D protein phosphatase, Mg2+/Mn2+ dependent, 1D
PPP1R13L protein phosphatase 1, regulatory subunit 13 like
PRKCD protein kinase C, delta
PRKCZ protein kinase C, zeta
PRKDC protein kinase, DNA-activated, catalytic polypeptide
PRNP prion protein
PTEN phosphatase and tensin homolog
RAB17 RAB17, member RAS oncogene family
RAB20 RAB20, member RAS oncogene family
RAD52 RAD52 homolog (S. cerevisiae)
RAD54L RAD54-like (S. cerevisiae)
RASIP1 Ras interacting protein 1
RB1 retinoblastoma 1
RBM17 RNA binding motif protein 17
RCAN1 regulator of calcineurin 1
RELA v-rel avian reticuloendotheliosis viral oncogene homolog A
ROBO1 roundabout, axon guidance receptor, homolog 1 (Drosophila)
ROPN1 rhophilin associated tail protein 1
RPL6 ribosomal protein L6
RPS27L ribosomal protein S27-like
RUNX1 runt-related transcription factor 1
RUNX3 runt-related transcription factor 3
S100P S100 calcium binding protein P
SLC16A6 solute carrier family 16, member 6
SLC22A18 solute carrier family 22, member 18
SLC27A3 solute carrier family 27 (fatty acid transporter), member 3
SLC7A5 solute carrier family 7 (amino acid transporter light chain, L system), member 5
SMAD2 SMAD family member 2
SMPDL3A sphingomyelin phosphodiesterase, acid-like 3A
SOD2 superoxide dismutase 2, mitochondrial
SORBS1 sorbin and SH3 domain containing 1
SORBS2 sorbin and SH3 domain containing 2
SORT1 sortilin 1
SOX10 SRY (sex determining region Y)-box 10
SP1 Sp1 transcription factor
SPP1 secreted phosphoprotein 1
SPTSSA serine palmitoyltransferase, small subunit A
ST3GAL5 ST3 beta-galactoside alpha-2,3-sialyltransferase 5
ST6GALNAC2 ST6 (alpha-N-acetyl-neuraminyl-2,3-beta-galactosyl-1,3)-N-acetylgalactosaminide alpha-2,6-sialyltransferase 2
ST7 suppression of tumorigenicity 7
STAT1 signal transducer and activator of transcription 1, 91kDa
TBPL1 TBP-like 1
TCFL5 transcription factor-like 5 (basic helix-loop-helix)
TDRD3 tudor domain containing 3
TFAP2A transcription factor AP-2 alpha (activating enhancer binding protein 2 alpha)
TFF3 trefoil factor 3 (intestinal)
TFPI tissue factor pathway inhibitor (lipoprotein-associated coagulation inhibitor)
TFPI2 tissue factor pathway inhibitor 2
TGDS TDP-glucose 4,6-dehydratase
TMC6 transmembrane channel-like 6
TMEM47 transmembrane protein 47
TMEM97 transmembrane protein 97
TMSB4X thymosin beta 4, X-linked
TNFRSF1A tumor necrosis factor receptor superfamily, member 1A
TNKS tankyrase, TRF1-interacting ankyrin-related ADP-ribose polymerase
TOP2A topoisomerase (DNA) II alpha 170kDa
TOP2B topoisomerase (DNA) II beta 180kDa
TP53 tumor protein p53
TP73 tumor protein p73
TPI1 triosephosphate isomerase 1
TPP2 tripeptidyl peptidase II
TPT1 tumor protein, translationally-controlled 1
TRAF2 TNF receptor-associated factor 2
TRIB2 tribbles pseudokinase 2
TRIM2 tripartite motif containing 2
TXN2 thioredoxin 2
TXNIP thioredoxin interacting protein
TYMS thymidylate synthetase
TYRP1 tyrosinase-related protein 1
UBL3 ubiquitin-like 3
UGT1A1 UDP glucuronosyltransferase 1 family, polypeptide A1
UGT1A3 UDP glucuronosyltransferase 1 family, polypeptide A3
UGT1A8 UDP glucuronosyltransferase 1 family, polypeptide A8
VCAM1 vascular cell adhesion molecule 1
VCAN versican
VDAC1 voltage-dependent anion channel 1
VDR vitamin D (1,25- dihydroxyvitamin D3) receptor
WIF1 WNT inhibitory factor 1
WIPI1 WD repeat domain, phosphoinositide interacting 1
WNT3A wingless-type MMTV integration site family, member 3A
WRN Werner syndrome, RecQ helicase-like
XAF1 XIAP associated factor 1
XRCC2 X-ray repair complementing defective repair in Chinese hamster cells 2
XRCC3 X-ray repair complementing defective repair in Chinese hamster cells 3
XRCC4 X-ray repair complementing defective repair in Chinese hamster cells 4
XRCC5 X-ray repair complementing defective repair in Chinese hamster cells 5 (double-strand-break rejoining)
ZDHHC11 zinc finger, DHHC-type containing 11
ZNF32 zinc finger protein 32
ZNRD1 zinc ribbon domain containing 1