| Dataset | Tahoe Therapeutics Tahoe 100M Perturbation Atlas |
| Category | transcriptomics |
| Type | cell type |
| Description | Everolimus perturbation in A-172 cell line (Tahoe Therapeutics) |
| Similar Terms | |
| Downloads & Tools |
200 genes differentially expressed following the Everolimus_A-172 drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| DCBLD2 | discoidin, CUB and LCCL domain containing 2 | 0.203956 |
| HSP90AB1 | heat shock protein 90kDa alpha (cytosolic), class B member 1 | 0.161327 |
| TRIO | trio Rho guanine nucleotide exchange factor | 0.142108 |
| HSP90AA1 | heat shock protein 90kDa alpha (cytosolic), class A member 1 | 0.122296 |
| SPTBN1 | spectrin, beta, non-erythrocytic 1 | 0.101537 |
| LDHA | lactate dehydrogenase A | 0.100649 |
| PLOD2 | procollagen-lysine, 2-oxoglutarate 5-dioxygenase 2 | 0.0927491 |
| KCNMA1 | potassium channel, calcium activated large conductance subfamily M alpha, member 1 | 0.0906486 |
| STAT1 | signal transducer and activator of transcription 1, 91kDa | 0.090481 |
| ENO1 | enolase 1, (alpha) | 0.0773492 |
| MAP1B | microtubule-associated protein 1B | 0.0753481 |
| HDAC9 | histone deacetylase 9 | 0.0705307 |
| RHOBTB3 | Rho-related BTB domain containing 3 | 0.06789 |
| EFNA5 | ephrin-A5 | 0.0675264 |
| CDH13 | cadherin 13 | 0.0655669 |
| CD44 | CD44 molecule (Indian blood group) | 0.0637157 |
| FLNA | filamin A, alpha | 0.0622179 |
| VIM | vimentin | 0.0621562 |
| ITGA2 | integrin, alpha 2 (CD49B, alpha 2 subunit of VLA-2 receptor) | 0.0615038 |
| PRELID2 | PRELI domain containing 2 | 0.0609471 |
| SAMD9 | sterile alpha motif domain containing 9 | 0.0590706 |
| SP100 | SP100 nuclear antigen | 0.0569935 |
| CALM1 | calmodulin 1 (phosphorylase kinase, delta) | 0.0569152 |
| ABL2 | ABL proto-oncogene 2, non-receptor tyrosine kinase | 0.0559714 |
| PKM | pyruvate kinase, muscle | 0.0545011 |
| PDIA3 | protein disulfide isomerase family A, member 3 | 0.0537408 |
| ALCAM | activated leukocyte cell adhesion molecule | 0.0535729 |
| RUNX1 | runt-related transcription factor 1 | 0.0530229 |
| ITGA3 | integrin, alpha 3 (antigen CD49C, alpha 3 subunit of VLA-3 receptor) | 0.051365 |
| DST | dystonin | 0.0501572 |
| PTPN14 | protein tyrosine phosphatase, non-receptor type 14 | 0.0488741 |
| HIVEP2 | human immunodeficiency virus type I enhancer binding protein 2 | 0.0487883 |
| PALM2AKAP2 | PALM2 and AKAP2 fusion | 0.0481629 |
| ANXA2 | annexin A2 | 0.0477964 |
| MT2A | metallothionein 2A | 0.0449537 |
| EGFR | epidermal growth factor receptor | 0.0443341 |
| KLF6 | Kruppel-like factor 6 | 0.0439355 |
| NAV2 | neuron navigator 2 | 0.0430592 |
| PBX3 | pre-B-cell leukemia homeobox 3 | 0.0426567 |
| BACE2 | beta-site APP-cleaving enzyme 2 | 0.0424911 |
| TPM3 | tropomyosin 3 | 0.0423522 |
| CACNA2D3 | calcium channel, voltage-dependent, alpha 2/delta subunit 3 | 0.0416696 |
| GBE1 | glucan (1,4-alpha-), branching enzyme 1 | 0.0410701 |
| LRRFIP1 | leucine rich repeat (in FLII) interacting protein 1 | 0.0404749 |
| EIF4G2 | eukaryotic translation initiation factor 4 gamma, 2 | 0.0400815 |
| SON | SON DNA binding protein | 0.0386232 |
| CDK6 | cyclin-dependent kinase 6 | 0.0379275 |
| CAPN2 | calpain 2, (m/II) large subunit | 0.0376929 |
| RPS3 | ribosomal protein S3 | 0.0374344 |
| MKI67 | marker of proliferation Ki-67 | 0.0374096 |
| SRRM2 | serine/arginine repetitive matrix 2 | 0.0371399 |
| ANKRD11 | ankyrin repeat domain 11 | 0.0366718 |
| YWHAZ | tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, zeta | 0.0363928 |
| NFE2L1 | nuclear factor, erythroid 2-like 1 | 0.0362692 |
| CENPF | centromere protein F, 350/400kDa | 0.0357465 |
| ARL6IP1 | ADP-ribosylation factor-like 6 interacting protein 1 | 0.0353745 |
| BNIP3L | BCL2/adenovirus E1B 19kDa interacting protein 3-like | 0.0351212 |
| PPP1R12A | protein phosphatase 1, regulatory subunit 12A | 0.0349008 |
| ANKIB1 | ankyrin repeat and IBR domain containing 1 | 0.0341788 |
| ASAP2 | ArfGAP with SH3 domain, ankyrin repeat and PH domain 2 | 0.0340258 |
| IFI6 | interferon, alpha-inducible protein 6 | 0.0336891 |
| CALR | calreticulin | 0.0336699 |
| HYOU1 | hypoxia up-regulated 1 | 0.033563 |
| MB21D2 | Mab-21 domain containing 2 | 0.0330982 |
| CSTB | cystatin B (stefin B) | 0.0330476 |
| ERBIN | erbb2 interacting protein | 0.0328596 |
| PRPF40A | PRP40 pre-mRNA processing factor 40 homolog A (S. cerevisiae) | 0.0322894 |
| BHLHE40 | basic helix-loop-helix family, member e40 | 0.0319565 |
| DOCK5 | dedicator of cytokinesis 5 | 0.0316758 |
| L1CAM | L1 cell adhesion molecule | 0.0316384 |
| SET | SET nuclear proto-oncogene | 0.0312308 |
| MBNL1 | muscleblind-like splicing regulator 1 | 0.0311526 |
| SQSTM1 | sequestosome 1 | 0.0310986 |
| HSP90B1 | heat shock protein 90kDa beta (Grp94), member 1 | 0.0303397 |
| PRRC2C | proline-rich coiled-coil 2C | 0.0303307 |
| SEPTIN7 | septin 7 | 0.0301061 |
| FAM107B | family with sequence similarity 107, member B | 0.0299155 |
| HERC4 | HECT and RLD domain containing E3 ubiquitin protein ligase 4 | 0.0298542 |
| BZW1 | basic leucine zipper and W2 domains 1 | 0.0297302 |
| CEP350 | centrosomal protein 350kDa | 0.0294859 |
| AGAP1 | ArfGAP with GTPase domain, ankyrin repeat and PH domain 1 | 0.0294858 |
| PRKCE | protein kinase C, epsilon | 0.0293111 |
| TPM4 | tropomyosin 4 | 0.0291419 |
| IGFBP7 | insulin-like growth factor binding protein 7 | 0.029018 |
| DCLK2 | doublecortin-like kinase 2 | 0.0288892 |
| ZMIZ1 | zinc finger, MIZ-type containing 1 | 0.028592 |
| BSG | basigin (Ok blood group) | 0.0283265 |
| RPS12 | ribosomal protein S12 | 0.0281337 |
| LOX | lysyl oxidase | 0.0280569 |
| HS3ST3A1 | heparan sulfate (glucosamine) 3-O-sulfotransferase 3A1 | 0.0279782 |
| SEPTIN2 | septin 2 | 0.0278321 |
| SEPTIN9 | septin 9 | 0.0278166 |
| SMC4 | structural maintenance of chromosomes 4 | 0.0278155 |
| EIF2AK2 | eukaryotic translation initiation factor 2-alpha kinase 2 | 0.0276513 |
| DSPP | dentin sialophosphoprotein | 0.0270814 |
| PITPNC1 | phosphatidylinositol transfer protein, cytoplasmic 1 | 0.0268552 |
| NAP1L1 | nucleosome assembly protein 1-like 1 | 0.0267217 |
| HIVEP3 | human immunodeficiency virus type I enhancer binding protein 3 | 0.0267182 |
| UBAP1 | ubiquitin associated protein 1 | 0.0264992 |
| CDC42EP3 | CDC42 effector protein (Rho GTPase binding) 3 | 0.0264034 |
| Symbol | Name | Standardized Value |
|---|---|---|
| IGFBP3 | insulin-like growth factor binding protein 3 | -0.375929 |
| GAPDH | glyceraldehyde-3-phosphate dehydrogenase | -0.147356 |
| SERPINE1 | serpin peptidase inhibitor, clade E (nexin, plasminogen activator inhibitor type 1), member 1 | -0.134793 |
| UBC | ubiquitin C | -0.100564 |
| FBN1 | fibrillin 1 | -0.0989159 |
| NDRG1 | N-myc downstream regulated 1 | -0.0987921 |
| ABI3BP | ABI family, member 3 (NESH) binding protein | -0.0866745 |
| IFIT2 | interferon-induced protein with tetratricopeptide repeats 2 | -0.0781545 |
| TMSB10 | thymosin beta 10 | -0.0756479 |
| LOXL2 | lysyl oxidase-like 2 | -0.0753212 |
| DIRAS3 | DIRAS family, GTP-binding RAS-like 3 | -0.0673469 |
| COL1A2 | collagen, type I, alpha 2 | -0.0666404 |
| SERPINE2 | serpin peptidase inhibitor, clade E (nexin, plasminogen activator inhibitor type 1), member 2 | -0.063202 |
| ADAMTS6 | ADAM metallopeptidase with thrombospondin type 1 motif, 6 | -0.0621811 |
| MARCKS | myristoylated alanine-rich protein kinase C substrate | -0.0620973 |
| HLA-B | major histocompatibility complex, class I, B | -0.0603638 |
| SPARC | secreted protein, acidic, cysteine-rich (osteonectin) | -0.0588834 |
| SOD2 | superoxide dismutase 2, mitochondrial | -0.0586348 |
| COL8A1 | collagen, type VIII, alpha 1 | -0.0542342 |
| SEMA5A | sema domain, seven thrombospondin repeats (type 1 and type 1-like), transmembrane domain (TM) and short cytoplasmic domain, (semaphorin) 5A | -0.0532364 |
| ACTG1 | actin gamma 1 | -0.0520327 |
| SCD | stearoyl-CoA desaturase (delta-9-desaturase) | -0.04958 |
| MT1X | metallothionein 1X | -0.0491679 |
| RPL35A | ribosomal protein L35a | -0.049122 |
| PLAT | plasminogen activator, tissue | -0.0478563 |
| AHNAK | AHNAK nucleoprotein | -0.0456598 |
| CD99 | CD99 molecule | -0.0452757 |
| S100A10 | S100 calcium binding protein A10 | -0.0452627 |
| ABCA1 | ATP-binding cassette, sub-family A (ABC1), member 1 | -0.0451401 |
| ZFP36L1 | ZFP36 ring finger protein-like 1 | -0.0438733 |
| EIF1 | eukaryotic translation initiation factor 1 | -0.0432098 |
| ZC3HAV1 | zinc finger CCCH-type, antiviral 1 | -0.0426395 |
| TM4SF1 | transmembrane 4 L six family member 1 | -0.0413635 |
| INSIG1 | insulin induced gene 1 | -0.0381609 |
| TNS3 | tensin 3 | -0.0353885 |
| JAZF1 | JAZF zinc finger 1 | -0.0352525 |
| SORBS2 | sorbin and SH3 domain containing 2 | -0.0327844 |
| CCND1 | cyclin D1 | -0.0325066 |
| HSPA5 | heat shock 70kDa protein 5 (glucose-regulated protein, 78kDa) | -0.0324977 |
| SPAG9 | sperm associated antigen 9 | -0.0309876 |
| OPTN | optineurin | -0.0307386 |
| TUBB | tubulin, beta class I | -0.0301271 |
| COL5A2 | collagen, type V, alpha 2 | -0.029873 |
| KDM3A | lysine (K)-specific demethylase 3A | -0.0295292 |
| TPT1 | tumor protein, translationally-controlled 1 | -0.0287207 |
| MRPS6 | mitochondrial ribosomal protein S6 | -0.0278484 |
| TPM1 | tropomyosin 1 (alpha) | -0.0278065 |
| TAPBP | TAP binding protein (tapasin) | -0.0274115 |
| SLC38A1 | solute carrier family 38, member 1 | -0.0267955 |
| LY6E | lymphocyte antigen 6 complex, locus E | -0.026721 |
| P4HA2 | prolyl 4-hydroxylase, alpha polypeptide II | -0.0267201 |
| HSPA9 | heat shock 70kDa protein 9 (mortalin) | -0.0265944 |
| FN1 | fibronectin 1 | -0.0265203 |
| ACBD3 | acyl-CoA binding domain containing 3 | -0.0263584 |
| DPYSL3 | dihydropyrimidinase-like 3 | -0.0258798 |
| IFIT3 | interferon-induced protein with tetratricopeptide repeats 3 | -0.0258728 |
| WTAP | Wilms tumor 1 associated protein | -0.0258201 |
| PPIB | peptidylprolyl isomerase B (cyclophilin B) | -0.02567 |
| NT5C2 | 5'-nucleotidase, cytosolic II | -0.0255405 |
| LMAN1 | lectin, mannose-binding, 1 | -0.0254425 |
| ADM | adrenomedullin | -0.0250861 |
| RNF168 | ring finger protein 168, E3 ubiquitin protein ligase | -0.0249803 |
| MAP3K2 | mitogen-activated protein kinase kinase kinase 2 | -0.0246596 |
| COL6A1 | collagen, type VI, alpha 1 | -0.0245721 |
| AUTS2 | autism susceptibility candidate 2 | -0.0244139 |
| SEC31A | SEC31 homolog A (S. cerevisiae) | -0.0243437 |
| CD63 | CD63 molecule | -0.0242453 |
| COL1A1 | collagen, type I, alpha 1 | -0.0241227 |
| CDK12 | cyclin-dependent kinase 12 | -0.0232935 |
| PABPC1 | poly(A) binding protein, cytoplasmic 1 | -0.0230696 |
| PTMA | prothymosin, alpha | -0.0230396 |
| IER3 | immediate early response 3 | -0.022773 |
| FGF13 | fibroblast growth factor 13 | -0.0226355 |
| COL3A1 | collagen, type III, alpha 1 | -0.0223315 |
| EIF4A2 | eukaryotic translation initiation factor 4A2 | -0.0222764 |
| TMEM158 | transmembrane protein 158 (gene/pseudogene) | -0.0220494 |
| TENT5A | terminal nucleotidyltransferase 5A | -0.0218305 |
| RHOQ | ras homolog family member Q | -0.0218002 |
| IL7R | interleukin 7 receptor | -0.0216304 |
| EPAS1 | endothelial PAS domain protein 1 | -0.0213727 |
| POLR2A | polymerase (RNA) II (DNA directed) polypeptide A, 220kDa | -0.020889 |
| IFIH1 | interferon induced with helicase C domain 1 | -0.0207249 |
| MSI2 | musashi RNA-binding protein 2 | -0.0205379 |
| GGNBP2 | gametogenetin binding protein 2 | -0.0204465 |
| COPB1 | coatomer protein complex, subunit beta 1 | -0.0203863 |
| CD55 | CD55 molecule, decay accelerating factor for complement (Cromer blood group) | -0.0203626 |
| DDX60 | DEAD (Asp-Glu-Ala-Asp) box polypeptide 60 | -0.0202601 |
| SUCNR1 | succinate receptor 1 | -0.019816 |
| PEA15 | phosphoprotein enriched in astrocytes 15 | -0.0197468 |
| SLC5A3 | solute carrier family 5 (sodium/myo-inositol cotransporter), member 3 | -0.0196848 |
| TMSB4X | thymosin beta 4, X-linked | -0.0192777 |
| RPS6KC1 | ribosomal protein S6 kinase, 52kDa, polypeptide 1 | -0.0192776 |
| RPL34 | ribosomal protein L34 | -0.0191691 |
| MYL12B | myosin, light chain 12B, regulatory | -0.0190755 |
| FLT1 | fms-related tyrosine kinase 1 | -0.0186314 |
| NAMPT | nicotinamide phosphoribosyltransferase | -0.0185805 |
| TFG | TRK-fused gene | -0.0185014 |
| RPS11 | ribosomal protein S11 | -0.0184495 |
| CCL5 | chemokine (C-C motif) ligand 5 | -0.0183467 |
| PRRX1 | paired related homeobox 1 | -0.0182625 |
