| Dataset | Tahoe Therapeutics Tahoe 100M Perturbation Atlas |
| Category | transcriptomics |
| Type | cell type |
| Description | Everolimus perturbation in CHP-212 cell line (Tahoe Therapeutics) |
| Similar Terms | |
| Downloads & Tools |
200 genes differentially expressed following the Everolimus_CHP-212 drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| VCL | vinculin | 0.121734 |
| AKAP12 | A kinase (PRKA) anchor protein 12 | 0.120531 |
| HSP90AB1 | heat shock protein 90kDa alpha (cytosolic), class B member 1 | 0.0914376 |
| PDE3A | phosphodiesterase 3A, cGMP-inhibited | 0.0880319 |
| LGR5 | leucine-rich repeat containing G protein-coupled receptor 5 | 0.0870515 |
| NFAT5 | nuclear factor of activated T-cells 5, tonicity-responsive | 0.080127 |
| AKAP9 | A kinase (PRKA) anchor protein 9 | 0.0733338 |
| TPST1 | tyrosylprotein sulfotransferase 1 | 0.0685349 |
| RPS12 | ribosomal protein S12 | 0.0662623 |
| PLPP1 | phospholipid phosphatase 1 | 0.0563903 |
| ENO1 | enolase 1, (alpha) | 0.0560318 |
| PSD3 | pleckstrin and Sec7 domain containing 3 | 0.0558462 |
| ZSWIM6 | zinc finger, SWIM-type containing 6 | 0.0510136 |
| ARID5B | AT rich interactive domain 5B (MRF1-like) | 0.0503331 |
| SYT1 | synaptotagmin I | 0.0500314 |
| GLCCI1 | glucocorticoid induced 1 | 0.0497684 |
| RNASEH2A | ribonuclease H2, subunit A | 0.0497429 |
| TLE4 | transducin-like enhancer of split 4 | 0.048744 |
| CD55 | CD55 molecule, decay accelerating factor for complement (Cromer blood group) | 0.0482706 |
| TIMP3 | TIMP metallopeptidase inhibitor 3 | 0.0467137 |
| ADAMTS9 | ADAM metallopeptidase with thrombospondin type 1 motif, 9 | 0.0458899 |
| RPS3 | ribosomal protein S3 | 0.0455462 |
| SQSTM1 | sequestosome 1 | 0.0455291 |
| STK38L | serine/threonine kinase 38 like | 0.0448744 |
| RPL17-C18ORF32 | RPL17-C18orf32 readthrough | 0.0434261 |
| PLOD2 | procollagen-lysine, 2-oxoglutarate 5-dioxygenase 2 | 0.0432029 |
| CTNNB1 | catenin (cadherin-associated protein), beta 1, 88kDa | 0.0431972 |
| NPAS2 | neuronal PAS domain protein 2 | 0.0429758 |
| BPTF | bromodomain PHD finger transcription factor | 0.0428223 |
| SLITRK6 | SLIT and NTRK-like family, member 6 | 0.0417341 |
| PTPRD | protein tyrosine phosphatase, receptor type, D | 0.0413102 |
| SRRM2 | serine/arginine repetitive matrix 2 | 0.0412803 |
| TCF7L2 | transcription factor 7-like 2 (T-cell specific, HMG-box) | 0.0405858 |
| FAM107B | family with sequence similarity 107, member B | 0.0401048 |
| HOMER1 | homer scaffolding protein 1 | 0.0396926 |
| HSPD1 | heat shock 60kDa protein 1 (chaperonin) | 0.0396619 |
| SIK2 | salt-inducible kinase 2 | 0.0394101 |
| MMP2 | matrix metallopeptidase 2 | 0.0392712 |
| MAN1A1 | mannosidase, alpha, class 1A, member 1 | 0.0390721 |
| ARIH1 | ariadne RBR E3 ubiquitin protein ligase 1 | 0.0389876 |
| SFTPA2 | surfactant protein A2 | 0.0386272 |
| RUNX1T1 | runt-related transcription factor 1; translocated to, 1 (cyclin D-related) | 0.0378295 |
| LIMA1 | LIM domain and actin binding 1 | 0.0375777 |
| ZC3HAV1 | zinc finger CCCH-type, antiviral 1 | 0.0374246 |
| MCL1 | myeloid cell leukemia 1 | 0.0364951 |
| EGR1 | early growth response 1 | 0.0364823 |
| PTEN | phosphatase and tensin homolog | 0.0363086 |
| HSP90AA1 | heat shock protein 90kDa alpha (cytosolic), class A member 1 | 0.0360291 |
| RPL37A | ribosomal protein L37a | 0.035473 |
| NR4A3 | nuclear receptor subfamily 4, group A, member 3 | 0.0348258 |
| MYCN | v-myc avian myelocytomatosis viral oncogene neuroblastoma derived homolog | 0.0339406 |
| ZMIZ1 | zinc finger, MIZ-type containing 1 | 0.0338976 |
| GBE1 | glucan (1,4-alpha-), branching enzyme 1 | 0.0336001 |
| TPM4 | tropomyosin 4 | 0.0332861 |
| MYO1E | myosin IE | 0.0331389 |
| PITPNC1 | phosphatidylinositol transfer protein, cytoplasmic 1 | 0.0331034 |
| CEMIP | cell migration inducing protein, hyaluronan binding | 0.032973 |
| MYH9 | myosin, heavy chain 9, non-muscle | 0.0327066 |
| PTPRK | protein tyrosine phosphatase, receptor type, K | 0.0325753 |
| PLCB1 | phospholipase C, beta 1 (phosphoinositide-specific) | 0.0325626 |
| TBX2 | T-box 2 | 0.0322533 |
| INTS6 | integrator complex subunit 6 | 0.0321975 |
| NPM1 | nucleophosmin (nucleolar phosphoprotein B23, numatrin) | 0.0321066 |
| DISP1 | dispatched homolog 1 (Drosophila) | 0.0320997 |
| RPL23 | ribosomal protein L23 | 0.0308434 |
| STAT3 | signal transducer and activator of transcription 3 (acute-phase response factor) | 0.0305999 |
| RPS2 | ribosomal protein S2 | 0.0301356 |
| NFE2L1 | nuclear factor, erythroid 2-like 1 | 0.0299868 |
| GPATCH8 | G patch domain containing 8 | 0.0299547 |
| PTPRE | protein tyrosine phosphatase, receptor type, E | 0.0299184 |
| NCAM2 | neural cell adhesion molecule 2 | 0.0298039 |
| MBNL1 | muscleblind-like splicing regulator 1 | 0.029682 |
| BICD1 | bicaudal D homolog 1 (Drosophila) | 0.0293433 |
| FHL2 | four and a half LIM domains 2 | 0.0292015 |
| ANGPTL4 | angiopoietin-like 4 | 0.0290661 |
| STAT1 | signal transducer and activator of transcription 1, 91kDa | 0.0289394 |
| CEMIP2 | cell migration inducing hyaluronidase 2 | 0.0287779 |
| CSNK1A1 | casein kinase 1, alpha 1 | 0.0281402 |
| DGKH | diacylglycerol kinase, eta | 0.0280481 |
| LDHA | lactate dehydrogenase A | 0.027724 |
| PELO | pelota homolog (Drosophila) | 0.0276973 |
| DUSP10 | dual specificity phosphatase 10 | 0.027586 |
| C6ORF62 | chromosome 6 open reading frame 62 | 0.0272279 |
| TMTC2 | transmembrane and tetratricopeptide repeat containing 2 | 0.0271692 |
| GPATCH2L | G patch domain containing 2-like | 0.0271063 |
| RPL7 | ribosomal protein L7 | 0.027055 |
| ITPRID2 | ITPR interacting domain containing 2 | 0.0270263 |
| VMP1 | vacuole membrane protein 1 | 0.0270083 |
| SCAPER | S-phase cyclin A-associated protein in the ER | 0.0269652 |
| KLHL13 | kelch-like family member 13 | 0.0267668 |
| HSPA8 | heat shock 70kDa protein 8 | 0.0267026 |
| LRRC23 | leucine rich repeat containing 23 | 0.0266227 |
| ANKS1A | ankyrin repeat and sterile alpha motif domain containing 1A | 0.0264957 |
| ACTN1 | actinin, alpha 1 | 0.0260402 |
| RPL27 | ribosomal protein L27 | 0.025991 |
| RPL12 | ribosomal protein L12 | 0.0258539 |
| ARB2A | ARB2 cotranscriptional regulator A | 0.0257799 |
| HPCAL1 | hippocalcin-like 1 | 0.0256928 |
| RIGI | RNA sensor RIG-I | 0.0254203 |
| PCDH17 | protocadherin 17 | 0.025412 |
| Symbol | Name | Standardized Value |
|---|---|---|
| GAPDH | glyceraldehyde-3-phosphate dehydrogenase | -0.191978 |
| COL1A1 | collagen, type I, alpha 1 | -0.129222 |
| RPL35A | ribosomal protein L35a | -0.102622 |
| NRG1 | neuregulin 1 | -0.0998497 |
| HSPA5 | heat shock 70kDa protein 5 (glucose-regulated protein, 78kDa) | -0.0897792 |
| HSP90B1 | heat shock protein 90kDa beta (Grp94), member 1 | -0.0842539 |
| FAM13A | family with sequence similarity 13, member A | -0.0733635 |
| NUCKS1 | nuclear casein kinase and cyclin-dependent kinase substrate 1 | -0.0729041 |
| UBR5 | ubiquitin protein ligase E3 component n-recognin 5 | -0.072611 |
| KDM3A | lysine (K)-specific demethylase 3A | -0.0703808 |
| NALF1 | NALCN channel auxiliary factor 1 | -0.0670225 |
| TOP2A | topoisomerase (DNA) II alpha 170kDa | -0.0656043 |
| PTMA | prothymosin, alpha | -0.0632385 |
| HELZ | helicase with zinc finger | -0.0605494 |
| HNRNPA2B1 | heterogeneous nuclear ribonucleoprotein A2/B1 | -0.0559654 |
| PABPC1 | poly(A) binding protein, cytoplasmic 1 | -0.0534228 |
| SETD5 | SET domain containing 5 | -0.0501484 |
| ACTG1 | actin gamma 1 | -0.0496579 |
| RBM39 | RNA binding motif protein 39 | -0.0491273 |
| NAMPT | nicotinamide phosphoribosyltransferase | -0.048453 |
| GNAS | GNAS complex locus | -0.047451 |
| KDM5B | lysine (K)-specific demethylase 5B | -0.0467023 |
| ADGRG6 | adhesion G protein-coupled receptor G6 | -0.0465843 |
| SMARCC1 | SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily c, member 1 | -0.0464752 |
| EIF1 | eukaryotic translation initiation factor 1 | -0.0453923 |
| CDH13 | cadherin 13 | -0.044609 |
| IGF2 | insulin-like growth factor 2 | -0.0445358 |
| HAND2 | heart and neural crest derivatives expressed 2 | -0.0441293 |
| AKT3 | v-akt murine thymoma viral oncogene homolog 3 | -0.0436697 |
| HIF1A | hypoxia inducible factor 1, alpha subunit (basic helix-loop-helix transcription factor) | -0.0430278 |
| OGA | O-GlcNAcase | -0.0424045 |
| LMNA | lamin A/C | -0.0418506 |
| MTHFD1L | methylenetetrahydrofolate dehydrogenase (NADP+ dependent) 1-like | -0.0408521 |
| COL3A1 | collagen, type III, alpha 1 | -0.0406019 |
| DCAF7 | DDB1 and CUL4 associated factor 7 | -0.0405764 |
| CDH2 | cadherin 2, type 1, N-cadherin (neuronal) | -0.040151 |
| VDAC1 | voltage-dependent anion channel 1 | -0.0400597 |
| C1ORF21 | chromosome 1 open reading frame 21 | -0.0400094 |
| NPEPPS | aminopeptidase puromycin sensitive | -0.0397822 |
| ARID1B | AT rich interactive domain 1B (SWI1-like) | -0.0381484 |
| RPS24 | ribosomal protein S24 | -0.0381091 |
| ZBTB20 | zinc finger and BTB domain containing 20 | -0.0376047 |
| SCD | stearoyl-CoA desaturase (delta-9-desaturase) | -0.0373433 |
| ROBO2 | roundabout, axon guidance receptor, homolog 2 (Drosophila) | -0.0367649 |
| QKI | QKI, KH domain containing, RNA binding | -0.0356333 |
| CCND1 | cyclin D1 | -0.0355618 |
| RBMX | RNA binding motif protein, X-linked | -0.0354024 |
| LCORL | ligand dependent nuclear receptor corepressor-like | -0.0352251 |
| RPL34 | ribosomal protein L34 | -0.0352001 |
| NF1 | neurofibromin 1 | -0.0348408 |
| SMURF2 | SMAD specific E3 ubiquitin protein ligase 2 | -0.0343867 |
| P4HB | prolyl 4-hydroxylase, beta polypeptide | -0.0336891 |
| DTNA | dystrobrevin, alpha | -0.0334754 |
| BMPR2 | bone morphogenetic protein receptor, type II (serine/threonine kinase) | -0.0334347 |
| PTK2 | protein tyrosine kinase 2 | -0.0330432 |
| TOMM20 | translocase of outer mitochondrial membrane 20 homolog (yeast) | -0.032947 |
| LUC7L3 | LUC7-like 3 (S. cerevisiae) | -0.0326977 |
| PPM1D | protein phosphatase, Mg2+/Mn2+ dependent, 1D | -0.032387 |
| WSB1 | WD repeat and SOCS box containing 1 | -0.0319365 |
| ACBD6 | acyl-CoA binding domain containing 6 | -0.0318263 |
| DDX17 | DEAD (Asp-Glu-Ala-Asp) box helicase 17 | -0.0315956 |
| ZNF609 | zinc finger protein 609 | -0.031417 |
| DDX5 | DEAD (Asp-Glu-Ala-Asp) box helicase 5 | -0.031125 |
| CDC27 | cell division cycle 27 | -0.0309246 |
| SLC38A2 | solute carrier family 38, member 2 | -0.030914 |
| PCDH9 | protocadherin 9 | -0.0304923 |
| PRR11 | proline rich 11 | -0.0304773 |
| WDR45B | WD repeat domain 45B | -0.0304235 |
| P4HA1 | prolyl 4-hydroxylase, alpha polypeptide I | -0.0303667 |
| GARS1 | glycyl-tRNA synthetase 1 | -0.0303116 |
| KMT2C | lysine (K)-specific methyltransferase 2C | -0.0302116 |
| UBC | ubiquitin C | -0.0301067 |
| KHDRBS1 | KH domain containing, RNA binding, signal transduction associated 1 | -0.0299409 |
| CENPE | centromere protein E, 312kDa | -0.0299149 |
| RBPJ | recombination signal binding protein for immunoglobulin kappa J region | -0.0298867 |
| DHX9 | DEAH (Asp-Glu-Ala-His) box helicase 9 | -0.0296534 |
| DLG1 | discs, large homolog 1 (Drosophila) | -0.0293005 |
| IL1RAPL1 | interleukin 1 receptor accessory protein-like 1 | -0.0292635 |
| ACBD3 | acyl-CoA binding domain containing 3 | -0.0289575 |
| SPAG9 | sperm associated antigen 9 | -0.0287751 |
| PUM2 | pumilio RNA-binding family member 2 | -0.0287093 |
| MAP4 | microtubule-associated protein 4 | -0.0285863 |
| CPED1 | cadherin-like and PC-esterase domain containing 1 | -0.0282163 |
| ASTN2 | astrotactin 2 | -0.0281124 |
| PACS1 | phosphofurin acidic cluster sorting protein 1 | -0.0280535 |
| DEK | DEK proto-oncogene | -0.0278666 |
| USP3 | ubiquitin specific peptidase 3 | -0.0278449 |
| SRP54 | signal recognition particle 54kDa | -0.0277673 |
| DYRK1A | dual-specificity tyrosine-(Y)-phosphorylation regulated kinase 1A | -0.0277379 |
| MAP3K2 | mitogen-activated protein kinase kinase kinase 2 | -0.027626 |
| ARF4 | ADP-ribosylation factor 4 | -0.0276236 |
| SNX9 | sorting nexin 9 | -0.0273753 |
| GSK3B | glycogen synthase kinase 3 beta | -0.0273524 |
| BIRC2 | baculoviral IAP repeat containing 2 | -0.027331 |
| PPP2CA | protein phosphatase 2, catalytic subunit, alpha isozyme | -0.0271561 |
| FAM162A | family with sequence similarity 162, member A | -0.0271422 |
| SPPL3 | signal peptide peptidase like 3 | -0.0271155 |
| PARD3 | par-3 family cell polarity regulator | -0.0270274 |
| RPS6KC1 | ribosomal protein S6 kinase, 52kDa, polypeptide 1 | -0.0269972 |
| RIOK3 | RIO kinase 3 | -0.0269077 |
