| Dataset | Tahoe Therapeutics Tahoe 100M Perturbation Atlas |
| Category | transcriptomics |
| Type | cell type |
| Description | Everolimus perturbation in COLO 205 cell line (Tahoe Therapeutics) |
| Similar Terms | |
| Downloads & Tools |
200 genes differentially expressed following the Everolimus_COLO 205 drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| NFAT5 | nuclear factor of activated T-cells 5, tonicity-responsive | 0.148835 |
| B2M | beta-2-microglobulin | 0.140297 |
| LCN2 | lipocalin 2 | 0.115974 |
| HKDC1 | hexokinase domain containing 1 | 0.0938679 |
| IFI6 | interferon, alpha-inducible protein 6 | 0.092287 |
| SLC12A2 | solute carrier family 12 (sodium/potassium/chloride transporter), member 2 | 0.0884271 |
| ANXA2 | annexin A2 | 0.086561 |
| MACC1 | metastasis associated in colon cancer 1 | 0.0861803 |
| INTS6 | integrator complex subunit 6 | 0.0783074 |
| MYO1E | myosin IE | 0.0769075 |
| HSP90AA1 | heat shock protein 90kDa alpha (cytosolic), class A member 1 | 0.0746901 |
| SIPA1L2 | signal-induced proliferation-associated 1 like 2 | 0.0746761 |
| ERN1 | endoplasmic reticulum to nucleus signaling 1 | 0.0732907 |
| SPTBN1 | spectrin, beta, non-erythrocytic 1 | 0.0728435 |
| FTH1 | ferritin, heavy polypeptide 1 | 0.0726136 |
| SYNE2 | spectrin repeat containing, nuclear envelope 2 | 0.0717992 |
| SQSTM1 | sequestosome 1 | 0.0700427 |
| LMO7 | LIM domain 7 | 0.0688682 |
| SERINC5 | serine incorporator 5 | 0.0675312 |
| TMC5 | transmembrane channel-like 5 | 0.0670794 |
| CTNNB1 | catenin (cadherin-associated protein), beta 1, 88kDa | 0.0613464 |
| LRCH1 | leucine-rich repeats and calponin homology (CH) domain containing 1 | 0.0609647 |
| EXT1 | exostosin glycosyltransferase 1 | 0.0604972 |
| HS2ST1 | heparan sulfate 2-O-sulfotransferase 1 | 0.0593449 |
| MAN1A1 | mannosidase, alpha, class 1A, member 1 | 0.0591501 |
| GCLC | glutamate-cysteine ligase, catalytic subunit | 0.0586836 |
| ARIH1 | ariadne RBR E3 ubiquitin protein ligase 1 | 0.0575437 |
| LIMA1 | LIM domain and actin binding 1 | 0.0560651 |
| B4GALT5 | UDP-Gal:betaGlcNAc beta 1,4- galactosyltransferase, polypeptide 5 | 0.0544934 |
| ENO1 | enolase 1, (alpha) | 0.0538509 |
| MAP7 | microtubule-associated protein 7 | 0.053814 |
| EPS8 | epidermal growth factor receptor pathway substrate 8 | 0.0534424 |
| HLA-A | major histocompatibility complex, class I, A | 0.053211 |
| RNASEH2A | ribonuclease H2, subunit A | 0.0529364 |
| FNDC3B | fibronectin type III domain containing 3B | 0.0527463 |
| ATP1B1 | ATPase, Na+/K+ transporting, beta 1 polypeptide | 0.0506489 |
| ELOF1 | elongation factor 1 homolog (S. cerevisiae) | 0.050406 |
| IFI27 | interferon, alpha-inducible protein 27 | 0.0500297 |
| YWHAZ | tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, zeta | 0.0490454 |
| PDZD8 | PDZ domain containing 8 | 0.048569 |
| CATSPERB | catsper channel auxiliary subunit beta | 0.0473441 |
| ZNF292 | zinc finger protein 292 | 0.0470057 |
| CXCL8 | chemokine (C-X-C motif) ligand 8 | 0.0464737 |
| SNTB1 | syntrophin, beta 1 (dystrophin-associated protein A1, 59kDa, basic component 1) | 0.0448996 |
| AKAP13 | A kinase (PRKA) anchor protein 13 | 0.0445867 |
| C6ORF132 | chromosome 6 open reading frame 132 | 0.0442101 |
| EREG | epiregulin | 0.0440909 |
| SMAD3 | SMAD family member 3 | 0.042462 |
| FNDC3A | fibronectin type III domain containing 3A | 0.0423581 |
| BAIAP2L1 | BAI1-associated protein 2-like 1 | 0.0422027 |
| KYNU | kynureninase | 0.0417923 |
| NFKBIZ | nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor, zeta | 0.0408546 |
| LURAP1L | leucine rich adaptor protein 1-like | 0.0406578 |
| ARHGAP5 | Rho GTPase activating protein 5 | 0.0387233 |
| FTL | ferritin, light polypeptide | 0.0386646 |
| RPS8 | ribosomal protein S8 | 0.0375236 |
| TJP1 | tight junction protein 1 | 0.0370233 |
| YAP1 | Yes-associated protein 1 | 0.0366549 |
| KLF6 | Kruppel-like factor 6 | 0.0356452 |
| TNFAIP3 | tumor necrosis factor, alpha-induced protein 3 | 0.035562 |
| FHIT | fragile histidine triad | 0.0351748 |
| PHACTR4 | phosphatase and actin regulator 4 | 0.0345583 |
| ZBTB43 | zinc finger and BTB domain containing 43 | 0.0345565 |
| DENND4C | DENN/MADD domain containing 4C | 0.0344791 |
| SHB | Src homology 2 domain containing adaptor protein B | 0.0342144 |
| PUM1 | pumilio RNA-binding family member 1 | 0.0341471 |
| FZR1 | fizzy/cell division cycle 20 related 1 (Drosophila) | 0.0340373 |
| DUSP16 | dual specificity phosphatase 16 | 0.0337067 |
| ITGA2 | integrin, alpha 2 (CD49B, alpha 2 subunit of VLA-2 receptor) | 0.0335269 |
| DIP2B | DIP2 disco-interacting protein 2 homolog B (Drosophila) | 0.0332808 |
| FOS | FBJ murine osteosarcoma viral oncogene homolog | 0.031786 |
| RPS12 | ribosomal protein S12 | 0.0314495 |
| GPBP1 | GC-rich promoter binding protein 1 | 0.0314294 |
| TNFRSF21 | tumor necrosis factor receptor superfamily, member 21 | 0.031075 |
| ETV6 | ets variant 6 | 0.030984 |
| FOSB | FBJ murine osteosarcoma viral oncogene homolog B | 0.0309208 |
| EML4 | echinoderm microtubule associated protein like 4 | 0.030894 |
| UBE2H | ubiquitin-conjugating enzyme E2H | 0.0304499 |
| RC3H1 | ring finger and CCCH-type domains 1 | 0.0301421 |
| USP54 | ubiquitin specific peptidase 54 | 0.0301076 |
| MEIS2 | Meis homeobox 2 | 0.0300503 |
| XDH | xanthine dehydrogenase | 0.0297195 |
| MT2A | metallothionein 2A | 0.0295715 |
| TNFRSF10B | tumor necrosis factor receptor superfamily, member 10b | 0.029416 |
| LPP | LIM domain containing preferred translocation partner in lipoma | 0.0294155 |
| NEBL | nebulette | 0.0291043 |
| AFF4 | AF4/FMR2 family, member 4 | 0.0289866 |
| SGK1 | serum/glucocorticoid regulated kinase 1 | 0.0288537 |
| TBL1XR1 | transducin (beta)-like 1 X-linked receptor 1 | 0.0287101 |
| SAMD9 | sterile alpha motif domain containing 9 | 0.0284291 |
| NCOA7 | nuclear receptor coactivator 7 | 0.0284041 |
| PLIN2 | perilipin 2 | 0.0283075 |
| LLGL2 | lethal giant larvae homolog 2 (Drosophila) | 0.0279512 |
| ZFP36L1 | ZFP36 ring finger protein-like 1 | 0.0278472 |
| CEMIP | cell migration inducing protein, hyaluronan binding | 0.0276772 |
| BAZ1A | bromodomain adjacent to zinc finger domain, 1A | 0.0274236 |
| TRIM2 | tripartite motif containing 2 | 0.0274154 |
| UBAP1 | ubiquitin associated protein 1 | 0.0272574 |
| TOX3 | TOX high mobility group box family member 3 | 0.0268604 |
| ANXA1 | annexin A1 | 0.0268335 |
| Symbol | Name | Standardized Value |
|---|---|---|
| UBC | ubiquitin C | -0.149735 |
| NDRG1 | N-myc downstream regulated 1 | -0.129286 |
| P4HB | prolyl 4-hydroxylase, beta polypeptide | -0.12528 |
| LYZ | lysozyme | -0.0988428 |
| GAPDH | glyceraldehyde-3-phosphate dehydrogenase | -0.0987345 |
| PTMA | prothymosin, alpha | -0.0904997 |
| HLA-B | major histocompatibility complex, class I, B | -0.0824026 |
| HSP90B1 | heat shock protein 90kDa beta (Grp94), member 1 | -0.0716129 |
| HSPA5 | heat shock 70kDa protein 5 (glucose-regulated protein, 78kDa) | -0.0698678 |
| IGFBP3 | insulin-like growth factor binding protein 3 | -0.0684067 |
| EIF1 | eukaryotic translation initiation factor 1 | -0.0653813 |
| TM4SF1 | transmembrane 4 L six family member 1 | -0.0623901 |
| AHNAK | AHNAK nucleoprotein | -0.0594615 |
| NPSR1 | neuropeptide S receptor 1 | -0.0593177 |
| RPL35A | ribosomal protein L35a | -0.05766 |
| RBM39 | RNA binding motif protein 39 | -0.0576344 |
| ACTG1 | actin gamma 1 | -0.0569847 |
| TNS4 | tensin 4 | -0.0549944 |
| PABPC1 | poly(A) binding protein, cytoplasmic 1 | -0.0493676 |
| ZMYND8 | zinc finger, MYND-type containing 8 | -0.0493149 |
| ARHGAP26 | Rho GTPase activating protein 26 | -0.0490707 |
| GMDS | GDP-mannose 4,6-dehydratase | -0.0452726 |
| SCD | stearoyl-CoA desaturase (delta-9-desaturase) | -0.0439495 |
| ATP11A | ATPase, class VI, type 11A | -0.0414787 |
| TMSB10 | thymosin beta 10 | -0.0411309 |
| UFM1 | ubiquitin-fold modifier 1 | -0.0397473 |
| POU2F2 | POU class 2 homeobox 2 | -0.0395497 |
| BTBD9 | BTB (POZ) domain containing 9 | -0.0392317 |
| MBNL2 | muscleblind-like splicing regulator 2 | -0.039153 |
| ACBD3 | acyl-CoA binding domain containing 3 | -0.0380029 |
| XAF1 | XIAP associated factor 1 | -0.0376983 |
| HLA-C | major histocompatibility complex, class I, C | -0.0373229 |
| TOP2A | topoisomerase (DNA) II alpha 170kDa | -0.0368088 |
| PDIA4 | protein disulfide isomerase family A, member 4 | -0.0366245 |
| EGR1 | early growth response 1 | -0.0351283 |
| AGAP1 | ArfGAP with GTPase domain, ankyrin repeat and PH domain 1 | -0.0345936 |
| DDX60 | DEAD (Asp-Glu-Ala-Asp) box polypeptide 60 | -0.0344868 |
| TBC1D22A | TBC1 domain family, member 22A | -0.0344475 |
| MUC13 | mucin 13, cell surface associated | -0.0336059 |
| DIAPH3 | diaphanous-related formin 3 | -0.0331593 |
| DDX5 | DEAD (Asp-Glu-Ala-Asp) box helicase 5 | -0.0327914 |
| EZR | ezrin | -0.0317628 |
| GOLGB1 | golgin B1 | -0.031756 |
| POLR2A | polymerase (RNA) II (DNA directed) polypeptide A, 220kDa | -0.0317129 |
| SREBF2 | sterol regulatory element binding transcription factor 2 | -0.0311875 |
| RFC3 | replication factor C (activator 1) 3, 38kDa | -0.0308703 |
| DDX17 | DEAD (Asp-Glu-Ala-Asp) box helicase 17 | -0.0307201 |
| CANX | calnexin | -0.0305287 |
| RBCK1 | RanBP-type and C3HC4-type zinc finger containing 1 | -0.0298628 |
| EGLN3 | egl-9 family hypoxia-inducible factor 3 | -0.0297968 |
| H1-0 | H1.0 linker histone | -0.0295449 |
| DDX60L | DEAD (Asp-Glu-Ala-Asp) box polypeptide 60-like | -0.0291119 |
| SMC4 | structural maintenance of chromosomes 4 | -0.0285325 |
| IRF1 | interferon regulatory factor 1 | -0.0284512 |
| S100A10 | S100 calcium binding protein A10 | -0.0281712 |
| EIF4A1 | eukaryotic translation initiation factor 4A1 | -0.0279522 |
| RPS6 | ribosomal protein S6 | -0.0275367 |
| LOC102724023 | ES1 protein homolog, mitochondrial | -0.0274963 |
| MPHOSPH8 | M-phase phosphoprotein 8 | -0.0274448 |
| MYH9 | myosin, heavy chain 9, non-muscle | -0.027343 |
| CALR | calreticulin | -0.0268557 |
| CDK12 | cyclin-dependent kinase 12 | -0.0266071 |
| ACSL3 | acyl-CoA synthetase long-chain family member 3 | -0.0260662 |
| AP2B1 | adaptor-related protein complex 2, beta 1 subunit | -0.0257439 |
| KLHL24 | kelch-like family member 24 | -0.0256918 |
| KDM3B | lysine (K)-specific demethylase 3B | -0.0252739 |
| TMPRSS4 | transmembrane protease, serine 4 | -0.024939 |
| HDAC4 | histone deacetylase 4 | -0.0249299 |
| PDE4D | phosphodiesterase 4D, cAMP-specific | -0.0246759 |
| RPL34 | ribosomal protein L34 | -0.0246389 |
| ATXN1 | ataxin 1 | -0.0243439 |
| AP3B1 | adaptor-related protein complex 3, beta 1 subunit | -0.024321 |
| DSCAML1 | Down syndrome cell adhesion molecule like 1 | -0.0241672 |
| VIM | vimentin | -0.0239731 |
| DNAJC3 | DnaJ (Hsp40) homolog, subfamily C, member 3 | -0.0239208 |
| IGF1R | insulin-like growth factor 1 receptor | -0.0238897 |
| PCK1 | phosphoenolpyruvate carboxykinase 1 (soluble) | -0.0236914 |
| PLSCR2 | phospholipid scramblase 2 | -0.0235501 |
| PDIA6 | protein disulfide isomerase family A, member 6 | -0.023395 |
| ASH1L | ash1 (absent, small, or homeotic)-like (Drosophila) | -0.0232525 |
| COPB1 | coatomer protein complex, subunit beta 1 | -0.0232226 |
| PPIB | peptidylprolyl isomerase B (cyclophilin B) | -0.0230761 |
| HNRNPA1 | heterogeneous nuclear ribonucleoprotein A1 | -0.0228051 |
| RPS19 | ribosomal protein S19 | -0.0226565 |
| LOC112694756 | uncharaterized LOC112694756 | -0.0224628 |
| PRSS22 | protease, serine, 22 | -0.0223194 |
| UGP2 | UDP-glucose pyrophosphorylase 2 | -0.0222258 |
| RPS29 | ribosomal protein S29 | -0.0219507 |
| OGA | O-GlcNAcase | -0.0217532 |
| SETX | senataxin | -0.0215857 |
| DEK | DEK proto-oncogene | -0.0215494 |
| SEC16A | SEC16 homolog A (S. cerevisiae) | -0.0215247 |
| TIPARP | TCDD-inducible poly(ADP-ribose) polymerase | -0.0214284 |
| ZNF638 | zinc finger protein 638 | -0.0214109 |
| CTNNA1 | catenin (cadherin-associated protein), alpha 1, 102kDa | -0.0213652 |
| GRIN2B | glutamate receptor, ionotropic, N-methyl D-aspartate 2B | -0.0212877 |
| SRP54 | signal recognition particle 54kDa | -0.0212864 |
| ATAD2 | ATPase family, AAA domain containing 2 | -0.0212825 |
| MKI67 | marker of proliferation Ki-67 | -0.0212719 |
| CALU | calumenin | -0.0210813 |
