| Dataset | Tahoe Therapeutics Tahoe 100M Perturbation Atlas |
| Category | transcriptomics |
| Type | cell type |
| Description | Everolimus perturbation in Hs 766T cell line (Tahoe Therapeutics) |
| Similar Terms | |
| Downloads & Tools |
200 genes differentially expressed following the Everolimus_Hs 766T drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| HSP90AA1 | heat shock protein 90kDa alpha (cytosolic), class A member 1 | 0.117743 |
| MBNL1 | muscleblind-like splicing regulator 1 | 0.116944 |
| NFATC2 | nuclear factor of activated T-cells, cytoplasmic, calcineurin-dependent 2 | 0.10496 |
| LMO7 | LIM domain 7 | 0.0991374 |
| FTH1 | ferritin, heavy polypeptide 1 | 0.0963532 |
| LRRFIP1 | leucine rich repeat (in FLII) interacting protein 1 | 0.0881437 |
| B2M | beta-2-microglobulin | 0.0821835 |
| HSP90AB1 | heat shock protein 90kDa alpha (cytosolic), class B member 1 | 0.0808128 |
| MYOF | myoferlin | 0.0806532 |
| DOK5 | docking protein 5 | 0.0804273 |
| LDHA | lactate dehydrogenase A | 0.0772408 |
| RPS12 | ribosomal protein S12 | 0.0737372 |
| CD44 | CD44 molecule (Indian blood group) | 0.0731247 |
| MTSS1 | metastasis suppressor 1 | 0.0704313 |
| CLU | clusterin | 0.0685771 |
| ENO1 | enolase 1, (alpha) | 0.066247 |
| MT2A | metallothionein 2A | 0.0644727 |
| ESYT2 | extended synaptotagmin-like protein 2 | 0.0633686 |
| MBNL2 | muscleblind-like splicing regulator 2 | 0.0632874 |
| IFIT3 | interferon-induced protein with tetratricopeptide repeats 3 | 0.0607957 |
| FNDC3B | fibronectin type III domain containing 3B | 0.0599617 |
| RPS8 | ribosomal protein S8 | 0.0583423 |
| IFITM1 | interferon induced transmembrane protein 1 | 0.0566521 |
| TXNIP | thioredoxin interacting protein | 0.0556797 |
| HIVEP2 | human immunodeficiency virus type I enhancer binding protein 2 | 0.0548903 |
| IFI44L | interferon-induced protein 44-like | 0.054422 |
| KTN1 | kinectin 1 (kinesin receptor) | 0.0535163 |
| MSN | moesin | 0.0532842 |
| SAMD9 | sterile alpha motif domain containing 9 | 0.0520419 |
| NFAT5 | nuclear factor of activated T-cells 5, tonicity-responsive | 0.049607 |
| BNIP3L | BCL2/adenovirus E1B 19kDa interacting protein 3-like | 0.0481138 |
| IFIT2 | interferon-induced protein with tetratricopeptide repeats 2 | 0.0480943 |
| SIK3 | SIK family kinase 3 | 0.0480404 |
| PDLIM5 | PDZ and LIM domain 5 | 0.0479426 |
| MEF2A | myocyte enhancer factor 2A | 0.0471911 |
| EIF2AK2 | eukaryotic translation initiation factor 2-alpha kinase 2 | 0.0465379 |
| RACK1 | receptor for activated C kinase 1 | 0.0451876 |
| TGM2 | transglutaminase 2 | 0.0446 |
| CAMK2D | calcium/calmodulin-dependent protein kinase II delta | 0.0439225 |
| SEPTIN9 | septin 9 | 0.0438147 |
| PICALM | phosphatidylinositol binding clathrin assembly protein | 0.0435307 |
| ZSWIM6 | zinc finger, SWIM-type containing 6 | 0.0435265 |
| KMT2E | lysine (K)-specific methyltransferase 2E | 0.0430017 |
| MT1E | metallothionein 1E | 0.0429507 |
| EXT1 | exostosin glycosyltransferase 1 | 0.0429154 |
| IFITM3 | interferon induced transmembrane protein 3 | 0.0421917 |
| CSNK1A1 | casein kinase 1, alpha 1 | 0.0421784 |
| ARHGAP21 | Rho GTPase activating protein 21 | 0.0407918 |
| RPL21 | ribosomal protein L21 | 0.0406304 |
| PDE4D | phosphodiesterase 4D, cAMP-specific | 0.0395373 |
| DIAPH1 | diaphanous-related formin 1 | 0.0394181 |
| RFX2 | regulatory factor X, 2 (influences HLA class II expression) | 0.0390898 |
| ECE1 | endothelin converting enzyme 1 | 0.038726 |
| ARIH1 | ariadne RBR E3 ubiquitin protein ligase 1 | 0.0386941 |
| DHX34 | DEAH (Asp-Glu-Ala-His) box polypeptide 34 | 0.0381244 |
| ATP2B4 | ATPase, Ca++ transporting, plasma membrane 4 | 0.0379624 |
| SRRM2 | serine/arginine repetitive matrix 2 | 0.037426 |
| HLA-E | major histocompatibility complex, class I, E | 0.0367559 |
| APLP2 | amyloid beta (A4) precursor-like protein 2 | 0.036427 |
| ANKRD28 | ankyrin repeat domain 28 | 0.0359147 |
| IFI27 | interferon, alpha-inducible protein 27 | 0.0357851 |
| IFI6 | interferon, alpha-inducible protein 6 | 0.0356908 |
| AKAP9 | A kinase (PRKA) anchor protein 9 | 0.0353583 |
| STAT1 | signal transducer and activator of transcription 1, 91kDa | 0.0352035 |
| RPL17-C18ORF32 | RPL17-C18orf32 readthrough | 0.035196 |
| RPS2 | ribosomal protein S2 | 0.0350297 |
| EIF4G2 | eukaryotic translation initiation factor 4 gamma, 2 | 0.03468 |
| NRIP1 | nuclear receptor interacting protein 1 | 0.0345729 |
| RNASEH2A | ribonuclease H2, subunit A | 0.0344687 |
| CNTNAP3 | contactin associated protein-like 3 | 0.0342152 |
| RPS6 | ribosomal protein S6 | 0.0339582 |
| SMAD3 | SMAD family member 3 | 0.0337705 |
| SYNE2 | spectrin repeat containing, nuclear envelope 2 | 0.0331622 |
| DNAJA1 | DnaJ (Hsp40) homolog, subfamily A, member 1 | 0.0328842 |
| RPL37 | ribosomal protein L37 | 0.032837 |
| RPS17 | ribosomal protein S17 | 0.0325734 |
| NECTIN1 | nectin cell adhesion molecule 1 | 0.0316504 |
| ANKRD12 | ankyrin repeat domain 12 | 0.0316479 |
| RPS6KA3 | ribosomal protein S6 kinase, 90kDa, polypeptide 3 | 0.0313122 |
| MYADM | myeloid-associated differentiation marker | 0.0312572 |
| SLC2A1 | solute carrier family 2 (facilitated glucose transporter), member 1 | 0.0311708 |
| EFNA5 | ephrin-A5 | 0.0307497 |
| JMJD1C | jumonji domain containing 1C | 0.0307416 |
| PELI2 | pellino E3 ubiquitin protein ligase family member 2 | 0.0306389 |
| FTL | ferritin, light polypeptide | 0.0304984 |
| CDKN2A | cyclin-dependent kinase inhibitor 2A | 0.0304653 |
| ANO6 | anoctamin 6 | 0.0299758 |
| ANXA1 | annexin A1 | 0.0298873 |
| PALM2AKAP2 | PALM2 and AKAP2 fusion | 0.0293356 |
| AKAP13 | A kinase (PRKA) anchor protein 13 | 0.0290867 |
| SLK | STE20-like kinase | 0.0290371 |
| SET | SET nuclear proto-oncogene | 0.0290226 |
| RPLP2 | ribosomal protein, large, P2 | 0.0286932 |
| RASAL2 | RAS protein activator like 2 | 0.0285588 |
| FOXP1 | forkhead box P1 | 0.0281882 |
| PITPNB | phosphatidylinositol transfer protein, beta | 0.0278281 |
| LUZP1 | leucine zipper protein 1 | 0.0278212 |
| RPL23 | ribosomal protein L23 | 0.0274895 |
| RPS3 | ribosomal protein S3 | 0.027298 |
| ITGA2 | integrin, alpha 2 (CD49B, alpha 2 subunit of VLA-2 receptor) | 0.026961 |
| Symbol | Name | Standardized Value |
|---|---|---|
| AHNAK | AHNAK nucleoprotein | -0.187458 |
| TIMP3 | TIMP metallopeptidase inhibitor 3 | -0.165325 |
| FLNB | filamin B, beta | -0.163005 |
| HSPA5 | heat shock 70kDa protein 5 (glucose-regulated protein, 78kDa) | -0.129786 |
| NAMPT | nicotinamide phosphoribosyltransferase | -0.0812228 |
| HSP90B1 | heat shock protein 90kDa beta (Grp94), member 1 | -0.0756338 |
| SULF1 | sulfatase 1 | -0.0749778 |
| H1-0 | H1.0 linker histone | -0.0747028 |
| DPYD | dihydropyrimidine dehydrogenase | -0.0742467 |
| PTMA | prothymosin, alpha | -0.0677709 |
| EMP1 | epithelial membrane protein 1 | -0.0669421 |
| PHLDB2 | pleckstrin homology-like domain, family B, member 2 | -0.0657291 |
| CANX | calnexin | -0.0640486 |
| RBM39 | RNA binding motif protein 39 | -0.0631362 |
| IL1RAPL1 | interleukin 1 receptor accessory protein-like 1 | -0.0608165 |
| KCNMA1 | potassium channel, calcium activated large conductance subfamily M alpha, member 1 | -0.0600098 |
| CD55 | CD55 molecule, decay accelerating factor for complement (Cromer blood group) | -0.0581861 |
| TMSB4X | thymosin beta 4, X-linked | -0.0581382 |
| ARFGEF2 | ADP-ribosylation factor guanine nucleotide-exchange factor 2 (brefeldin A-inhibited) | -0.0534598 |
| GAPDH | glyceraldehyde-3-phosphate dehydrogenase | -0.0509518 |
| S100A10 | S100 calcium binding protein A10 | -0.0486493 |
| CUL4B | cullin 4B | -0.0483816 |
| PGK1 | phosphoglycerate kinase 1 | -0.0468684 |
| ANLN | anillin, actin binding protein | -0.0463053 |
| DDX17 | DEAD (Asp-Glu-Ala-Asp) box helicase 17 | -0.0456972 |
| ADAMTS6 | ADAM metallopeptidase with thrombospondin type 1 motif, 6 | -0.0442785 |
| RPS21 | ribosomal protein S21 | -0.0425232 |
| DDX60L | DEAD (Asp-Glu-Ala-Asp) box polypeptide 60-like | -0.0411643 |
| TPT1 | tumor protein, translationally-controlled 1 | -0.039936 |
| ANO1 | anoctamin 1, calcium activated chloride channel | -0.0398294 |
| GRB10 | growth factor receptor-bound protein 10 | -0.0396373 |
| RAI14 | retinoic acid induced 14 | -0.0387321 |
| SCD | stearoyl-CoA desaturase (delta-9-desaturase) | -0.0376731 |
| ANKRD11 | ankyrin repeat domain 11 | -0.0365696 |
| AP3B1 | adaptor-related protein complex 3, beta 1 subunit | -0.0361207 |
| KDM3A | lysine (K)-specific demethylase 3A | -0.0352844 |
| DLG1 | discs, large homolog 1 (Drosophila) | -0.0345532 |
| VDAC1 | voltage-dependent anion channel 1 | -0.0339571 |
| ERO1A | endoplasmic reticulum oxidoreductase 1 alpha | -0.0338469 |
| IARS1 | isoleucyl-tRNA synthetase 1 | -0.0337923 |
| SRGAP1 | SLIT-ROBO Rho GTPase activating protein 1 | -0.032695 |
| HIVEP3 | human immunodeficiency virus type I enhancer binding protein 3 | -0.0322046 |
| ZEB1 | zinc finger E-box binding homeobox 1 | -0.0320237 |
| TM4SF1 | transmembrane 4 L six family member 1 | -0.0318881 |
| PODXL | podocalyxin-like | -0.0318654 |
| CAPZA1 | capping protein (actin filament) muscle Z-line, alpha 1 | -0.0318114 |
| HYCC2 | hyccin PI4KA lipid kinase complex subunit 2 | -0.0317499 |
| FUT8 | fucosyltransferase 8 (alpha (1,6) fucosyltransferase) | -0.0317238 |
| SPAG9 | sperm associated antigen 9 | -0.0316267 |
| NAV2 | neuron navigator 2 | -0.0314319 |
| UFM1 | ubiquitin-fold modifier 1 | -0.0313352 |
| NF1 | neurofibromin 1 | -0.0309862 |
| HSD17B2 | hydroxysteroid (17-beta) dehydrogenase 2 | -0.0308462 |
| FSTL1 | follistatin-like 1 | -0.0308147 |
| TNS3 | tensin 3 | -0.030708 |
| OGA | O-GlcNAcase | -0.0307036 |
| LMAN1 | lectin, mannose-binding, 1 | -0.0307013 |
| NUCKS1 | nuclear casein kinase and cyclin-dependent kinase substrate 1 | -0.0304804 |
| ARF4 | ADP-ribosylation factor 4 | -0.0301257 |
| CALU | calumenin | -0.0300678 |
| IER3 | immediate early response 3 | -0.0299252 |
| MBOAT2 | membrane bound O-acyltransferase domain containing 2 | -0.0298478 |
| FSCN1 | fascin actin-bundling protein 1 | -0.0295859 |
| PJA2 | praja ring finger 2, E3 ubiquitin protein ligase | -0.0293616 |
| NPEPPS | aminopeptidase puromycin sensitive | -0.0293242 |
| SERPINE1 | serpin peptidase inhibitor, clade E (nexin, plasminogen activator inhibitor type 1), member 1 | -0.0293229 |
| KDM5B | lysine (K)-specific demethylase 5B | -0.0292635 |
| SEC31A | SEC31 homolog A (S. cerevisiae) | -0.029127 |
| MAP4K4 | mitogen-activated protein kinase kinase kinase kinase 4 | -0.0287885 |
| NRCAM | neuronal cell adhesion molecule | -0.0285073 |
| SBF2 | SET binding factor 2 | -0.0284433 |
| RRBP1 | ribosome binding protein 1 | -0.0282145 |
| ARPC5 | actin related protein 2/3 complex, subunit 5, 16kDa | -0.0280837 |
| HLA-B | major histocompatibility complex, class I, B | -0.028069 |
| CALM2 | calmodulin 2 (phosphorylase kinase, delta) | -0.0280169 |
| SF3B2 | splicing factor 3b, subunit 2, 145kDa | -0.0279806 |
| UBC | ubiquitin C | -0.0278774 |
| WSB1 | WD repeat and SOCS box containing 1 | -0.027829 |
| ABI3BP | ABI family, member 3 (NESH) binding protein | -0.0277272 |
| THSD4 | thrombospondin, type I, domain containing 4 | -0.0275711 |
| SDCBP | syndecan binding protein (syntenin) | -0.0273795 |
| TMEM263 | transmembrane protein 263 | -0.0273278 |
| SEMA4B | sema domain, immunoglobulin domain (Ig), transmembrane domain (TM) and short cytoplasmic domain, (semaphorin) 4B | -0.0272195 |
| ADAMTS16 | ADAM metallopeptidase with thrombospondin type 1 motif, 16 | -0.0269461 |
| COL17A1 | collagen, type XVII, alpha 1 | -0.0260111 |
| EXOC6B | exocyst complex component 6B | -0.0258395 |
| GARS1 | glycyl-tRNA synthetase 1 | -0.0256416 |
| CEP170 | centrosomal protein 170kDa | -0.0255608 |
| ZMYND8 | zinc finger, MYND-type containing 8 | -0.0254226 |
| DDX60 | DEAD (Asp-Glu-Ala-Asp) box polypeptide 60 | -0.0249888 |
| RICTOR | RPTOR independent companion of MTOR, complex 2 | -0.0247713 |
| MT1X | metallothionein 1X | -0.0247647 |
| RSL1D1 | ribosomal L1 domain containing 1 | -0.0246114 |
| COL4A5 | collagen, type IV, alpha 5 | -0.0244403 |
| RAB1A | RAB1A, member RAS oncogene family | -0.0239418 |
| FOSL1 | FOS-like antigen 1 | -0.0234562 |
| EPB41L1 | erythrocyte membrane protein band 4.1-like 1 | -0.0233578 |
| CAVIN1 | caveolae associated protein 1 | -0.0232105 |
| LAMC2 | laminin, gamma 2 | -0.0229648 |
| ACTG1 | actin gamma 1 | -0.0227424 |
