| Dataset | Tahoe Therapeutics Tahoe 100M Perturbation Atlas |
| Category | transcriptomics |
| Type | cell type |
| Description | Everolimus perturbation in KATO III cell line (Tahoe Therapeutics) |
| Similar Terms | |
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200 genes differentially expressed following the Everolimus_KATO III drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| HSP90AA1 | heat shock protein 90kDa alpha (cytosolic), class A member 1 | 0.243674 |
| CEACAM5 | carcinoembryonic antigen-related cell adhesion molecule 5 | 0.142747 |
| LMO7 | LIM domain 7 | 0.0931953 |
| CTNNB1 | catenin (cadherin-associated protein), beta 1, 88kDa | 0.09038 |
| HYOU1 | hypoxia up-regulated 1 | 0.0827158 |
| HSP90AB1 | heat shock protein 90kDa alpha (cytosolic), class B member 1 | 0.0787104 |
| TMC5 | transmembrane channel-like 5 | 0.0737568 |
| SPTBN1 | spectrin, beta, non-erythrocytic 1 | 0.071677 |
| ANXA1 | annexin A1 | 0.0700471 |
| MBNL1 | muscleblind-like splicing regulator 1 | 0.069036 |
| MBNL2 | muscleblind-like splicing regulator 2 | 0.0637501 |
| LCN2 | lipocalin 2 | 0.0630483 |
| MAML2 | mastermind-like 2 (Drosophila) | 0.0622069 |
| ITGA6 | integrin, alpha 6 | 0.06192 |
| FNDC3B | fibronectin type III domain containing 3B | 0.0603269 |
| NFAT5 | nuclear factor of activated T-cells 5, tonicity-responsive | 0.0589437 |
| ASPH | aspartate beta-hydroxylase | 0.0552575 |
| PTPRK | protein tyrosine phosphatase, receptor type, K | 0.0549338 |
| ATXN1 | ataxin 1 | 0.0530984 |
| IFI6 | interferon, alpha-inducible protein 6 | 0.0510826 |
| APLP2 | amyloid beta (A4) precursor-like protein 2 | 0.0488593 |
| ENO1 | enolase 1, (alpha) | 0.0467741 |
| BAIAP2L1 | BAI1-associated protein 2-like 1 | 0.04639 |
| ATF5 | activating transcription factor 5 | 0.0457757 |
| MYO1E | myosin IE | 0.0451661 |
| IFI27 | interferon, alpha-inducible protein 27 | 0.0451292 |
| FRMD5 | FERM domain containing 5 | 0.0445242 |
| ZSWIM6 | zinc finger, SWIM-type containing 6 | 0.043246 |
| HKDC1 | hexokinase domain containing 1 | 0.041674 |
| RPS12 | ribosomal protein S12 | 0.0415739 |
| GULP1 | GULP, engulfment adaptor PTB domain containing 1 | 0.0413619 |
| AKAP13 | A kinase (PRKA) anchor protein 13 | 0.0404031 |
| PDIA3 | protein disulfide isomerase family A, member 3 | 0.0401998 |
| SEPTIN9 | septin 9 | 0.0399875 |
| KLHL29 | kelch-like family member 29 | 0.039655 |
| RNF213 | ring finger protein 213 | 0.0395217 |
| ITGA2 | integrin, alpha 2 (CD49B, alpha 2 subunit of VLA-2 receptor) | 0.0392276 |
| EHBP1 | EH domain binding protein 1 | 0.039105 |
| LOC102724023 | ES1 protein homolog, mitochondrial | 0.0388084 |
| IMMP2L | IMP2 inner mitochondrial membrane peptidase-like (S. cerevisiae) | 0.0387436 |
| SLC2A1 | solute carrier family 2 (facilitated glucose transporter), member 1 | 0.0387257 |
| SYNE2 | spectrin repeat containing, nuclear envelope 2 | 0.0386154 |
| AHR | aryl hydrocarbon receptor | 0.038584 |
| PPP1R15A | protein phosphatase 1, regulatory subunit 15A | 0.0381862 |
| DOCK5 | dedicator of cytokinesis 5 | 0.0376227 |
| ATP1B1 | ATPase, Na+/K+ transporting, beta 1 polypeptide | 0.0372799 |
| FAM135A | family with sequence similarity 135, member A | 0.0371376 |
| CDK6 | cyclin-dependent kinase 6 | 0.0369817 |
| RPS7 | ribosomal protein S7 | 0.0369582 |
| IL1RAP | interleukin 1 receptor accessory protein | 0.036928 |
| FTH1 | ferritin, heavy polypeptide 1 | 0.0368883 |
| GDA | guanine deaminase | 0.0367478 |
| PTPN12 | protein tyrosine phosphatase, non-receptor type 12 | 0.0362758 |
| SLTM | SAFB-like, transcription modulator | 0.036029 |
| LPP | LIM domain containing preferred translocation partner in lipoma | 0.0354318 |
| BACE2 | beta-site APP-cleaving enzyme 2 | 0.0352912 |
| UBE2H | ubiquitin-conjugating enzyme E2H | 0.0350793 |
| PCSK5 | proprotein convertase subtilisin/kexin type 5 | 0.0343956 |
| EFNA5 | ephrin-A5 | 0.0342494 |
| ARHGAP29 | Rho GTPase activating protein 29 | 0.033421 |
| CMIP | c-Maf inducing protein | 0.0333595 |
| EEPD1 | endonuclease/exonuclease/phosphatase family domain containing 1 | 0.033072 |
| ATP11A | ATPase, class VI, type 11A | 0.0330026 |
| RASEF | RAS and EF-hand domain containing | 0.0328004 |
| VMP1 | vacuole membrane protein 1 | 0.0325521 |
| NCEH1 | neutral cholesterol ester hydrolase 1 | 0.0323626 |
| PKM | pyruvate kinase, muscle | 0.0320175 |
| SET | SET nuclear proto-oncogene | 0.0315954 |
| ALCAM | activated leukocyte cell adhesion molecule | 0.0312628 |
| INTS6 | integrator complex subunit 6 | 0.0308673 |
| RPS3 | ribosomal protein S3 | 0.0308351 |
| HSPA8 | heat shock 70kDa protein 8 | 0.0306667 |
| IGF2BP2 | insulin-like growth factor 2 mRNA binding protein 2 | 0.030615 |
| NEDD4L | neural precursor cell expressed, developmentally down-regulated 4-like, E3 ubiquitin protein ligase | 0.0303527 |
| SLCO1B3 | solute carrier organic anion transporter family, member 1B3 | 0.0302319 |
| LURAP1L | leucine rich adaptor protein 1-like | 0.0296126 |
| PRAG1 | PEAK1 related, kinase-activating pseudokinase 1 | 0.029561 |
| YAP1 | Yes-associated protein 1 | 0.029464 |
| AKAP9 | A kinase (PRKA) anchor protein 9 | 0.0294085 |
| VEGFA | vascular endothelial growth factor A | 0.0294064 |
| RUNX1 | runt-related transcription factor 1 | 0.0291683 |
| PDLIM5 | PDZ and LIM domain 5 | 0.0286202 |
| ERRFI1 | ERBB receptor feedback inhibitor 1 | 0.0285773 |
| CATSPERB | catsper channel auxiliary subunit beta | 0.028544 |
| YWHAZ | tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, zeta | 0.0283084 |
| CDK13 | cyclin-dependent kinase 13 | 0.0282658 |
| AREG | amphiregulin | 0.0280816 |
| MYADM | myeloid-associated differentiation marker | 0.0279633 |
| ASAP2 | ArfGAP with SH3 domain, ankyrin repeat and PH domain 2 | 0.0279073 |
| EZR | ezrin | 0.0279071 |
| WWOX | WW domain containing oxidoreductase | 0.0279068 |
| CUX1 | cut-like homeobox 1 | 0.0279031 |
| DSPP | dentin sialophosphoprotein | 0.0275533 |
| EIF2AK2 | eukaryotic translation initiation factor 2-alpha kinase 2 | 0.0275245 |
| ANXA3 | annexin A3 | 0.0273732 |
| ANP32B | acidic (leucine-rich) nuclear phosphoprotein 32 family, member B | 0.0272882 |
| POF1B | premature ovarian failure, 1B | 0.0270223 |
| TMTC2 | transmembrane and tetratricopeptide repeat containing 2 | 0.026763 |
| AGR3 | anterior gradient 3 | 0.0266053 |
| SIK3 | SIK family kinase 3 | 0.0264104 |
| Symbol | Name | Standardized Value |
|---|---|---|
| GAPDH | glyceraldehyde-3-phosphate dehydrogenase | -0.2113 |
| NPSR1 | neuropeptide S receptor 1 | -0.177813 |
| FGFR2 | fibroblast growth factor receptor 2 | -0.17625 |
| EIF1 | eukaryotic translation initiation factor 1 | -0.130556 |
| RPL35A | ribosomal protein L35a | -0.123749 |
| HSPA5 | heat shock 70kDa protein 5 (glucose-regulated protein, 78kDa) | -0.0925733 |
| H1-0 | H1.0 linker histone | -0.0915017 |
| AGR2 | anterior gradient 2 | -0.0911879 |
| ACTG1 | actin gamma 1 | -0.0774772 |
| HSD17B12 | hydroxysteroid (17-beta) dehydrogenase 12 | -0.0754954 |
| SCD | stearoyl-CoA desaturase (delta-9-desaturase) | -0.0749215 |
| S100A10 | S100 calcium binding protein A10 | -0.0642606 |
| KRT8 | keratin 8, type II | -0.0624136 |
| AHNAK | AHNAK nucleoprotein | -0.0597133 |
| PPDPF | pancreatic progenitor cell differentiation and proliferation factor | -0.0564424 |
| TMSB10 | thymosin beta 10 | -0.055669 |
| PPIB | peptidylprolyl isomerase B (cyclophilin B) | -0.0524435 |
| RPS6 | ribosomal protein S6 | -0.0523849 |
| INSIG1 | insulin induced gene 1 | -0.0505349 |
| ANLN | anillin, actin binding protein | -0.0503702 |
| PABPC1 | poly(A) binding protein, cytoplasmic 1 | -0.0484505 |
| CEACAM6 | carcinoembryonic antigen-related cell adhesion molecule 6 (non-specific cross reacting antigen) | -0.0484188 |
| CANX | calnexin | -0.048293 |
| ACSS2 | acyl-CoA synthetase short-chain family member 2 | -0.0472952 |
| LOC112694756 | uncharaterized LOC112694756 | -0.0472621 |
| RBM39 | RNA binding motif protein 39 | -0.0446005 |
| TPT1 | tumor protein, translationally-controlled 1 | -0.0438763 |
| UBC | ubiquitin C | -0.0430726 |
| SREBF2 | sterol regulatory element binding transcription factor 2 | -0.0427061 |
| RPL34 | ribosomal protein L34 | -0.0426965 |
| PDIA4 | protein disulfide isomerase family A, member 4 | -0.0414754 |
| S100A6 | S100 calcium binding protein A6 | -0.0412114 |
| PTMA | prothymosin, alpha | -0.0409205 |
| PRSS3 | protease, serine, 3 | -0.0398031 |
| RPS19 | ribosomal protein S19 | -0.0396795 |
| HMGA1 | high mobility group AT-hook 1 | -0.0390789 |
| DEK | DEK proto-oncogene | -0.0390355 |
| POTEF | POTE ankyrin domain family, member F | -0.0388081 |
| FDFT1 | farnesyl-diphosphate farnesyltransferase 1 | -0.0387424 |
| RPS21 | ribosomal protein S21 | -0.0383259 |
| KRT7 | keratin 7, type II | -0.0382288 |
| NDRG1 | N-myc downstream regulated 1 | -0.0381332 |
| GPX2 | glutathione peroxidase 2 | -0.0373888 |
| RPS11 | ribosomal protein S11 | -0.0373032 |
| ACACA | acetyl-CoA carboxylase alpha | -0.0371273 |
| RRBP1 | ribosome binding protein 1 | -0.0369288 |
| ASNS | asparagine synthetase (glutamine-hydrolyzing) | -0.0365945 |
| WDR45B | WD repeat domain 45B | -0.0362353 |
| RBCK1 | RanBP-type and C3HC4-type zinc finger containing 1 | -0.0353016 |
| RPL8 | ribosomal protein L8 | -0.035109 |
| PGK1 | phosphoglycerate kinase 1 | -0.0336115 |
| SAMD12 | sterile alpha motif domain containing 12 | -0.0334015 |
| TM4SF1 | transmembrane 4 L six family member 1 | -0.0333362 |
| TAX1BP1 | Tax1 (human T-cell leukemia virus type I) binding protein 1 | -0.0333247 |
| CHCHD2 | coiled-coil-helix-coiled-coil-helix domain containing 2 | -0.0332891 |
| RPL11 | ribosomal protein L11 | -0.0331712 |
| FASN | fatty acid synthase | -0.0320507 |
| RPLP1 | ribosomal protein, large, P1 | -0.0317979 |
| CLDN7 | claudin 7 | -0.031689 |
| LYZ | lysozyme | -0.0315734 |
| KDM3A | lysine (K)-specific demethylase 3A | -0.0315001 |
| ACTN4 | actinin, alpha 4 | -0.0313395 |
| RPL23 | ribosomal protein L23 | -0.0311127 |
| LMAN1 | lectin, mannose-binding, 1 | -0.0305657 |
| CD2AP | CD2-associated protein | -0.0302964 |
| MDK | midkine (neurite growth-promoting factor 2) | -0.0302558 |
| HMGCS1 | 3-hydroxy-3-methylglutaryl-CoA synthase 1 (soluble) | -0.0297633 |
| TMPRSS4 | transmembrane protease, serine 4 | -0.0297594 |
| IRF1 | interferon regulatory factor 1 | -0.0296358 |
| EMP1 | epithelial membrane protein 1 | -0.0292161 |
| MAP1LC3B | microtubule-associated protein 1 light chain 3 beta | -0.0291291 |
| ACSL3 | acyl-CoA synthetase long-chain family member 3 | -0.0283367 |
| TRIM31 | tripartite motif containing 31 | -0.0281793 |
| ATP5F1B | ATP synthase F1 subunit beta | -0.0280555 |
| P4HB | prolyl 4-hydroxylase, beta polypeptide | -0.0279639 |
| ARF1 | ADP-ribosylation factor 1 | -0.0279284 |
| ACSL1 | acyl-CoA synthetase long-chain family member 1 | -0.0272291 |
| HLA-C | major histocompatibility complex, class I, C | -0.0267967 |
| CEP95 | centrosomal protein 95kDa | -0.0266694 |
| ARFGEF2 | ADP-ribosylation factor guanine nucleotide-exchange factor 2 (brefeldin A-inhibited) | -0.0266206 |
| RPS29 | ribosomal protein S29 | -0.0264564 |
| KRT18 | keratin 18, type I | -0.0262658 |
| RAB1A | RAB1A, member RAS oncogene family | -0.0260564 |
| TMSB4X | thymosin beta 4, X-linked | -0.0259842 |
| TMBIM1 | transmembrane BAX inhibitor motif containing 1 | -0.0250075 |
| RPL32 | ribosomal protein L32 | -0.0249374 |
| FDPS | farnesyl diphosphate synthase | -0.024937 |
| CEMIP | cell migration inducing protein, hyaluronan binding | -0.0249169 |
| MYL12B | myosin, light chain 12B, regulatory | -0.0245166 |
| NCOR1 | nuclear receptor corepressor 1 | -0.0237685 |
| ACSL4 | acyl-CoA synthetase long-chain family member 4 | -0.0237134 |
| RPS23 | ribosomal protein S23 | -0.0235764 |
| IER3 | immediate early response 3 | -0.0233016 |
| IDI1 | isopentenyl-diphosphate delta isomerase 1 | -0.0230154 |
| PRRC2B | proline-rich coiled-coil 2B | -0.0229537 |
| KRT17 | keratin 17, type I | -0.0229405 |
| WASF2 | WAS protein family, member 2 | -0.0229072 |
| SELENOK | selenoprotein K | -0.0226475 |
| TSPAN3 | tetraspanin 3 | -0.0226012 |
| ARPC2 | actin related protein 2/3 complex, subunit 2, 34kDa | -0.0225925 |
